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Evidence for enduring deficits after the resolution of visuo-spatial neglect

2013

BIAL Foundation Archive
- BIAL Grants
  - 2010 Grants
    - 155 - Memory for personal experience and the parietal cortex
      - Evidence for enduring deficits after the resolution of visuo-spatial neglect

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2010
Location:	Arquivo PCA - Pastas 1 a 23
Title:	2010 Grants
Start date:	2011-01

Reference code:	PT/FB/BL-2010-155
Location:	Arquivo PCA - Pasta 21/2010
Title:	155 - Memory for personal experience and the parietal cortex
Duration:	2011-06 - 2015-09
Researcher(s):	Charlotte Russell, Paresh Malhotra, Adrian Williams
Institution(s):	Centre for Cognition and Neuroimaging, Department of Psychology, Brunel University, Uxbridge (UK)
Contents:	Contents: Bursary agreement Application form Correspondence Financial report and expenditure documents Progress report Final report
Language:	eng
Author:	Russell, C.
Secondary author(s):	Malhotra, P., Williams, A.
Number of reproductions:	1
Keywords:	Psychophysiology / Cognitive processes / Memory / Brain structure and function

Reference code:	PT/FB/BL-2010-155.03
Location:	Arquivo PCA - Pasta 21/2010
Title:	Evidence for enduring deficits after the resolution of visuo-spatial neglect
Publication year:	2013
URL:	http://www.esn2013.org/program/symposia/symposium-20-compensatory-mechanisms-in-visual-neglect/
Abstract/Results:	ABSTRACT: Neglect frequently resolves spontaneously-however many patients continue to suffer from a number of important and frequently overlooked deficits. These residual deficits involve a number of critical functions associated with parietal cortex: attention; remapping of spatial information across saccades; spatial aspects of long-term memory. First, patients with resolved neglect appear to suffer from a pathological loss of attention capacity. We have shown this by modulating the difficulty of a task at fixation and assessing the impact of this manipulation on perception across the visual field. Patients with right parietal lesions – but without neglect - are impaired in detecting contralesional stimuli only when central task difficulty is high. Further, this impairment extends temporally leading to a spatiotemporal ‘attentional blink’ in which patients are unable to detect contralesional stimuli for a lag of up to 500 ms (Russell et al, 2004; Russell et al, 2012). Second, after neglect has resolved a considerable number of patients continue to suffer from constructional apraxia, such that they are unable to copy drawings or 3D constructions. We have assessed spatial remapping across saccades in these individuals and have shown a specific impairment in remapping location information, as compared to pattern information (Russell et al, 2010). Recently, in recovered neglect patients with right parietal damage we have assessed whether deficits in spatial representation can be revealed in tests of long-term memory. This has proved to be the case as, despite having no memory deficits in standard neuropsychological tests, when examined with a paradigm designed to examine personal spatial perspective within episodic memory, patients with right parietal damage are greatly impaired. The results of these three lines of research will be discussed in relation to enduring dysfunction following right parietal damage, and how this might relate to the neglect syndrome itself.
Accessibility:	Document does not exist in file
Language:	eng
Author:	Russell, C.
Document type:	Online abstract
Number of reproductions:	1
Reference:	Russell, C. (2013, September). Evidence for enduring deficits after the resolution of visuo-spatial neglect. In M. Bonato & P. Bartolomeo (Chair), Compensatory mechanisms in visual neglect. Symposium conducted at the 4th meeting of the European Societies of Neuropsychology, Berlin, Germany. Abstract retrieved from http://www.esn2013.org/program/symposia/symposium-20-compensatory-mechanisms-in-visual-neglect/
Indexed document:	No
Keywords:	Neglect / Parietal cortex / Attention / Spatial representation / Episodic memory / Spatial remapping