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DE:"Auditory evoked potentials (AEPs)"
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DocumentDifferential effects of frequency adaptation and sequential predictability on auditory evoked potentials2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.05
Location: Arquivo PCA - Pasta 2/2010
Title:
Differential effects of frequency adaptation and sequential predictability on auditory evoked potentials
Publication year: 2011
URL:
http://www.frontiersin.org/10.3389/conf.fnhum.2011.207.00350/event_abstract
Abstract/Results: ABSTRACT:
Auditory processing can be modulated by the stimulation context, as for instance seen in a suppression of electrical brain activity in response to repeated and predictable sounds. To determine whether context effects relying on repetition-related frequency adaptation or on more complex forms of predictability share similar processing stages, we recorded human auditory evoked potentials (AEPs) in the range of the middle- and long-latency response (MLR, LLR) in a paradigm isolating the effects of stimulus probability and stimulus predictability. The same tone was presented in different contexts: either a) taking the role of a frequent tone (p = 0.8), or being presented in a block of five equi-probable tones of different frequencies, which occurred b) in a regular descending pattern, or c) in random order (serving as a control condition). Increased stimulus probability was associated with an attenuated Nb component (41-47ms) of the MLR and with a reduced early phase of N1 (80-100ms) of the LLR with the specific pattern of results indicating cross-frequency adaptation to be narrower at the level of the Nb compared to N1. Predictable, but rare, stimuli were associated with a slow wave starting before tone onset and an amplitude reduction of the Pa component (31-37ms) of the MLR and the later portion of N1 (120-150ms) of the LLR. The findings suggest that repeated input is filtered by probability-dependent frequency adaptation at different processing stages. Modulations of the AEP related to stimulus predictability suggest that the auditory system encodes regular sequential patterns and suppresses responses to predictable stimuli. Importantly, the neural processes showing probability-related adaptation can be dissociated from those sensitive to sequential predictability.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Grimm, S.
Secondary author(s):
Escera, C.
Document type:
Abstract
Number of reproductions:
1
Reference:
Grimm, S., & Escera, C. (2011). Differential effects of frequency adaptation and sequential predictability on auditory evoked potentials. Frontiers in Human Neuroscience. Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI). https://doi.org/10.3389/conf.fnhum.2011.207.00350
Indexed document: Yes
Keywords: Auditory evoked potentials (AEPs) / Perception
DocumentEarly automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.07
Location: Arquivo PCA - Pasta 2/2010
Title:
Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response
Publication year: 2011
URL:
http://www.cogneurosociety.org/wordpress/wp-content/themes/CNStheme/downloads/CNS2011_Program.pdf
Abstract/Results: ABSTRACT:
The violation of a regular sound pattern by irregular or novel stimuli is reflected in the mismatch negativity, a component of the human auditory evoked potential (AEP), with a latency of 100-250 ms and main sources in the auditory cortices. Evidence for auditory novelty detection however has also been reported at much shorter latencies (15 ?– 30 ms after stimulus onset) as revealed by single- and multiunit recordings in the auditory cortex and midbrain of animals. In this study, we aimed at finding traces of fast auditory novelty detection in the human AEP during a passive intensity oddball paradigm. An oddball condition using click stimuli (standard stimulus = 50 dB SL; deviant stimulus [14%] = 40 dB SL), a reversed oddball condition (standard stimulus = 40 dB SL; deviant stimulus [14%] = 50 dB SL) and a control condition (random presentation of 7 stimuli with different intensities ranging from 10-70 dB SL, 14 % probability each) were applied. The EEG was recorded from 7 scalp electrodes and the data was analyzed in the ranges of the auditory brainstem response, the middle-latency response, and the long-latency response. In the middle-latency range, deviants elicited a significantly more negative response than standards of the same intensity
at the descending slope of the Na component (21-27 ms after stimulus onset). This outcome suggests that the human auditory novelty detection system comprises fast processes which are taking place at latencies similar to those found in single- and multiunit recordings in animals.
Accessibility: Document does not exist in file
Language:
eng
Author:
Althen, H.
Secondary author(s):
Grimm, S., Slabu, L., Escera, C.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Althen, H., Grimm, S., Slabu, L., & Escera, C. (2011). Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response. In Abstract book of the Cognitive Neuroscience Society - 2011 Annual Meeting (pp. 35-36). San Francisco, CA.
Indexed document: No
Keywords: Mismatch negativity (MMN) / Auditory evoked potentials (AEPs) / Auditory novelty detection

Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response

Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response
DocumentRapid detection of changes in sound source location as revealed by human auditory evoked potentials2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.08
Location: Arquivo PCA - Pasta 2/2010
Title:
Rapid detection of changes in sound source location as revealed by human auditory evoked potentials
Publication year: 2011
URL:
http://www.cogneurosociety.org/wordpress/wp-content/themes/CNStheme/downloads/CNS2011_Program.pdf
Abstract/Results: ABSTRACT:
The rapid discrimination of sound source locations is crucial in order to group the auditory input and to selectively attend to specific sound sources. The detection of changes in sound location has been related to the mismatch negativity (MMN), an auditory evoked potential (AEP) occurring at 100-250 ms after change onset. However, animal recordings suggest much faster neural responses to contextually new or deviant stimuli and recent studies have observed early indices of human auditory deviance detection for spectral changes in the middle-latency response (MLR) of the AEP. The present study investigates the processing of sound location changes by measuring the MLR during an oddball paradigm in 20 human subjects. The auditory sequences were comprised of clicks presented via loudspeakers in oddball blocks (80 % standards: 30^(0); 20 % deviants: 60^(0)), reversed oddball blocks (standards: 60^(0); deviants: 30^(0)), and control blocks (randomly from -60^(0), - 30^(0), 0^(0), 30^(0), 60^(0)). Oddball blocks were presented both in the left and right hemifield. Clicks presented at deviant locations elicited a larger Na component of the MLR peaking at 17-23 ms compared to clicks presented at the same site when it served as the standard or control location. Whereas the Na component itself was not lateralized, the deviancerelated increase in Na amplitude showed a significant dominance over the hemisphere contralateral to the side of stimulation. This indicates that the discrimination of rare spatial changes initiates very quickly, at about 20 ms after sound onset, reflected by an enhanced activity dominantly in contralateral auditory cortex regions.
Accessibility: Document does not exist in file
Language:
eng
Author:
Grimm, S.
Secondary author(s):
Althen, H., Recasens, M., Escera, C.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Grimm, S., Althen, H., Recasens, M., & Escera, C. (2011). Rapid detection of changes in sound source location as revealed by human auditory evoked potentials. In Abstract book of the Cognitive Neuroscience Society - 2011 Annual Meeting (p. 21). San Francisco, CA.
Indexed document: No
Keywords: Mismatch negativity (MMN) / Auditory evoked potentials (AEPs) / Deviant sounds

Rapid detection of changes in sound source location as revealed by human auditory evoked potentials

Rapid detection of changes in sound source location as revealed by human auditory evoked potentials