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DocumentIndependent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-096
Location: Arquivo PCA - Pasta 6/2002
Title:
096 - Face processing in 3-day-olds: an electrophysiological approach
Duration: 2003-01 - 2005-02
Researcher(s):
Olivier Pascalis, de Haan Michelle, Saachi Reza
Institution(s): Department of Psychology, The University of Sheffield (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Article
Language: eng
Author:
Pascalis, O.
Secondary author(s):
Haan, M., Saatchi, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Brain structure and function

Reference code: PT/FB/BL-2002-096.03
Location: Arquivo PCA - Pasta 6/2002
Title:
Independent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism
Publication year: 2009
URL:
http://www.sciencedirect.com/science/article/pii/S000632230800886X
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=294&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
BACKGROUND:
Individuals with autistic spectrum disorder (ASD) experience atypical visual perception, yet the etiology of this remains unknown. The aim of this study was to investigate the neural correlates of visual perception in individuals with and without ASD by carrying out a detailed analysis of the dynamic brain processes elicited by perception of a simple visual stimulus.
METHODS:
We investigated perception in 20 individuals with ASD and 20 control subjects with electroencephalography (EEG). Visual evoked potentials elicited by Gabor patches of varying spatial frequency and stimulus-induced changes in a- and ?-frequency bands of independent components were compared in those with and without ASD.
RESULTS:
By decomposing the EEG data into independent components, we identified several processes that contributed to the average event related potential recorded at the scalp. Differences between the ASD and control groups were found only in some of these processes. Specifically, in those components that were in or near the striate or extrastriate cortex, stimulus spatial frequency exerted a smaller effect on induced increases in a- and ?-band power, and time to peak a-band power was reduced, in the participants with ASD. Induced a-band power of components that were in or near the cingulate gyrus was increased in the participants with ASD, and the components that were in or near the parietal cortex did not differ between the two groups.
CONCLUSION:
Atypical processing is evident in individuals with ASD during perception of simple visual stimuli. The implications of these data for existing theories of atypical perception in ASD are discussed.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Milne, E.
Secondary author(s):
Scope, A., Pascalis, O., Buckley, D., Makeig, S.
Document type:
Article
Number of reproductions:
1
Reference:
Milne, E., Scope, A., Pascalis, O., Buckley, D., & Makeig, S. (2009). Independent Component Analysis Reveals Atypical Electroencephalographic Activity During Visual Perception in Individuals with Autism. Biological Psychiatry, 65(1), 22-30. https://doi.org/10.1016/j.biopsych.2008.07.017
2-year Impact Factor: 8.926|2009
Times cited: 105|2025-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Alpha power / Autism / Cingulate Gyrus / Gamma power / Perception / Spatial frequency / Visual cortex

Novo ficheiro

Novo ficheiro
DocumentIndependent component analysis reveals atypical EEG activity during visual perception in individuals with autism2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-047
Location: Arquivo PCA - Pasta 3/2004
Title:
047 - A combined psychophysiological and electrophysiological approach to investigate low-level visual perception in autism
Duration: 2005-06 - 2006-10
Researcher(s):
Olivier Pascalis, Elizabeth Milne, David Buckley, Laurence Vigon
Institution(s): Department of Psychology, The University of Sheffield (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Poster
1 Article
Journal Cahiers de Psychologie Cognitive/ Current Psychology of Cognition
Language: eng
Author:
Pascalis, O.
Secondary author(s):
Milne, E., Buckley, D., Vigon, L.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Biopsychological problems / Childhood and adolescent disorders / Autism spectrum disorder (ASD) / Cognitive processes / Perception

Reference code: PT/FB/BL-2004-047.02
Location: Arquivo PCA - Pasta 3/2004
Title:
Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism
Publication year: 2009
URL:
http://www.biologicalpsychiatryjournal.com/article/S0006-3223(08)00886-X/abstract
Abstract/Results: ABSTRACT:
BACKGROUND:
Individuals with autistic spectrum disorder (ASD) experience atypical visual perception, yet the etiology of this remains unknown. The aim of this study was to investigate the neural correlates of visual perception in individuals with and without ASD by carrying out a detailed analysis of the dynamic brain processes elicited by perception of a simple visual stimulus.
METHODS:
We investigated perception in 20 individuals with ASD and 20 control subjects with electroencephalograph(EEG). Visual evoked potentials elicited by Gabor patches of varying spatial frequency and stimulus-induced changes in a- and ?-frequency bands of independent components were compared in those with and without ASD.
RESULTS:
By decomposing the EEG data into independent components, we identified several processes that contributed to the average event related potential recorded at the scalp. Differences between the ASD and control groups were found only in some of these processes. Specifically, in those components that were in or near the striate or extrastriate cortex, stimulus spatial frequency exerted a smaller effect on induced increases in a- and ?-band power, and time to peak a-band power was reduced, in the participants with ASD. Induced a-band power of components that were in or near the cingulate gyrus was increased in the participants with ASD, and the components that were in or near the parietal cortex did not differ between the two groups.
CONCLUSIONS:
Atypical processing is evident in individuals with ASD during perception of simple visual stimuli. The implications of these data for existing theories of atypical perception in ASD are discussed.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Milne, E.
Secondary author(s):
Scope, A., Pascalis, O., Buckley, D., Makeig, S.
Document type:
Article
Number of reproductions:
1
Reference:
Milne, E., Scope, A., Pascalis, O., Buckley, D., & Makeig, S. (2009). Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism. Biological Psychiatry, 65(1), 22-30. https://doi.org/10.1016/j.biopsych.2008.07.017
2-year Impact Factor: 8.926|2009
Times cited: 105|2025-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Alpha power / Autism / Cingulate gyrus / Gamma power / Perception / Spatial frequency / Visual cortex

Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism

Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism
DocumentInverted event-related potentials response to illusory contour in boys with autism2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-087
Location: Arquivo PCA - Pasta 9/2004
Title:
087 - Early neurophysiological correlates of autism: visual attention and EEG rhythms
Duration: 2005-01 - 2007-04
Researcher(s):
Stroganova Tatiana Alexandrovna, Elam Mikael, Orekhova Elena, Tsetlin Mariana Mihailovna, Morozov Alexei Alexandrovich
Institution(s): Moscow University for Psychology and Education, Faculty of Abnormal Psychology, Moscow (Russia)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
2 Articles
3 Unpublished document (1 poster and 2 articles submitted for publication)
Language: eng
Author:
Stroganova, T. A.
Secondary author(s):
Elam, M., Orekhova, E. V., Tsetlin, M. M., Morozov, A. A.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Childhood and adolescent disorders / Autism spectrum disorder (ASD)

Reference code: PT/FB/BL-2004-087.02
Location: Arquivo PCA - Pasta 9/2004
Title:
Inverted event-related potentials response to illusory contour in boys with autism
Publication year: 2007
URL:
http://www.academia.edu/1984981/Inverted_event-related_potentials_response_to_illusory_contour_in_boys_with_autism
Abstract/Results: ABSTRACT:
We examined the hypothesis of lower-level processing abnormalities related to perceptual grouping in boys with autism aged 3-6 years. We investigated event-related potentials response to visual elements that either formed perceptually coherent illusory contour or were arranged in a noncoherent way. The results showed that in healthy boys the illusory contour as compared with control stimulus elicited enhanced negativity of N1 peak (C effect), which has been previously found in adults. Autistic boys demonstrated the reliable inverted illusory contour effect, that is, more positive N1 amplitude to illusory contour. We hypothesized that boys with autism were sensitive to difference between illusory contour and control figures basing on collinearity processing mechanisms implemented in neural circuitry of primary visual cortex.
Accessibility: Document does not exist in file
Language:
eng
Author:
Stroganova, T. A.
Secondary author(s):
Orekhova, E. V., Prokofyev, A. O., Posikera, I. N., Morozov, A. A., Obukhov, Y. V., Morozov, V. A.
Document type:
Article
Number of reproductions:
1
Reference:
Stroganova, T. A., Orekhova, E. V., Prokofyev, A. O., Posikera, I. N., Morozov, A. A., Obukhov, Y. V., & Morozov, V. A. (2007). Inverted event-related potentials response to illusory contour in boys with autism. Neuroreport, 18 (9), 931-935. https://doi.org/10.1097/WNR.0b013e32811e151b
2-year Impact Factor: 2.163|2007
Times cited: 18|2025-02-04
Indexed document: Yes
Quartile: Q3
Keywords: Autism / Children / Event-related gestalt perception / Kanizsa square / Occipital cortex / Potentials
Document"EuroTheory of mind" and its neuronal correlates in forensically relevant disorders2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-054
Location: Arquivo PCA - Pasta 3/2008
Title:
054 - Brain activity during remote information access
Duration: 2009-10 - 2011-06
Researcher(s):
Jérôme Daltrozzo, Boris Kotchoubey, Ahmed A. Karim
Institution(s): Institute of Medical Psychology and Behavioral Neurobiology, Eberhard-Karls-University, Tübingen (Germany)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Articles
Language: eng
Author:
Daltrozzo, J.
Secondary author(s):
Kotchoubey, B., Karim, A. A.
Number of reproductions:
1
Keywords:
Psychophysiology / Out-of-body experience (OBE) / Brain structure and function / Sleep and dreams / Body awareness

Reference code: PT/FB/BL-2008-054.04
Location: Arquivo PCA - Pasta 3/2008
Title:
"EuroTheory of mind" and its neuronal correlates in forensically relevant disorders
Publication year: 2011
URL:
http://www.researchgate.net/publication/46289244_Theory_of_mind_and_its_neuronal_correlates_in_forensically_relevant_disorders
Abstract/Results: ABSTRACT:
Theory of mind (ToM), the ability to recognize mental states of others, and empathy are crucial cognitive-emotional processes for appropriate social interactions. Deficits in these processes can lead to maladjusted social behavior or even to aggressive or criminal behavior. ToM and empathy deficits have been found in different forensically relevant disorders, such as schizophrenia, pedophilia but especially in autism and psychopathy according to Hare. Most notably, autistic and psychopathic patients differ in their type of deficits and in their neuronal correlates. While autistic individuals lack the ability to take the perspective of others, psychopaths lack empathy. The aim of this article is to provide a better understanding of the pathophysiology of ToM and empathy deficits in forensically relevant disorders by reviewing and discussing the findings of neuroimaging and lesion studies and to highlight crucial implications for neuropsychotherapy according to Grawe.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
ger
Author:
Krippl, M.
Secondary author(s):
Karim, A. A.
Document type:
Article
Number of reproductions:
1
Reference:
Krippl, M., & Karim, A. A. (2011). "EuroTheory of mind" and its neuronal correlates in forensically relevant disorders. Nervenarzt, 82(7), 843-852. https://doi.org/10.1007/s00115-010-3073-x
2-year Impact Factor: 0.681|2011
Times cited: 14|2025-02-10
Indexed document: Yes
Quartile: Q4
Keywords: Theory of mind / Empathy / Autism / Schizophrenia / Neurology

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DocumentHigh motion coherence thresholds in children with autism2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/082
Location: Arquivo PCA - Pasta 3/2004
Title:
High motion coherence thresholds in children with autism
Publication year: 2002
Número de inventário:
M-0085
URL: http://www.ncbi.nlm.nih.gov/pubmed/11902604
Abstract/Results: ABSTRACT:
BACKGROUND: We assessed motion processing in a group of high functioning children with autism and a group of typically developing children, using a coherent motion detection task.
METHOD: Twenty-five children with autism (mean age 11 years, 8 months) and 22 typically developing children matched for non-verbal mental ability and chronological age were required to detect the direction of moving dots in a random dot kinematogram.
RESULTS: The group of children with autism showed significantly higher motion coherence thresholds than the typically developing children (i.e., they showed an impaired ability to detect coherent motion).
CONCLUSIONS: This finding suggests that some individuals with autism may show impairments in low-level visual processing--specifically in the magnocellular visual pathway. The findings are discussed in terms of implications for higher-level cognitive theories of autism, and the suggestion is made that more work needs to be carried out to further investigate low-level visual processing in autism.
Accessibility: Document does not exist in file
Language:
eng
Author:
Milne, E.
Secondary author(s):
Swettenham, J., Hansen, P., Campbell, R., Jeffries, H., Plaisted, K.
Document type:
Article
Reference:
Milne, E., Swettenham, J., Hansen, P., Campbell, R., Jeffries, H., & Plaisted, K. (2002). High motion coherence thresholds in children with autism. Journal of Child Psychology and Psychiatry, 43(2), 255-263.
Impact factor notes: Impact factor only available after 2007
Indexed document: Yes
Keywords: Children / Autism / Motion detection / Visual processing / Cognitive impairment

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DocumentNeural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-133
Location: Arquivo PCA - Pasta 9/2012
Title:
133 - The role of the core and extended face networks in visual perception and high level social cognition
Duration: 2013-11 - 2016-01
Researcher(s):
Miguel Castelo-Branco, Marco Simões, Carlos Amaral, Gregor Philipiak, José Rebola, João Castelhano
Institution(s): IBILI, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Simões, M., Amaral, C., Philipiak, G., Rebola, J., Castelhano, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Perception / Attention / Affective and social behavior / Social cognition / Brain structure and function

Reference code: PT/FB/BL-2012-133.08
Location: Arquivo PCA - Pasta 9/2012
Title:
Neural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized
Publication year: 2015
URL:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121970
Abstract/Results: ABSTRACT:
Classification of neural signals at the single-trial level and the study of their relevance in affective and cognitive neuroscience are still in their infancy. Here we investigated the neurophysiological correlates of conditions of increasing social scene complexity using 3D human models as targets of attention, which may also be important in autism research. Challenging single-trial statistical classification of EEG neural signals was attempted for detection of oddball stimuli with increasing social scene complexity. Stimuli had an oddball structure and were as follows: 1) flashed schematic eyes, 2) simple 3D faces flashed between averted and non-averted gaze (only eye position changing), 3) simple 3D faces flashed between averted and non-averted gaze (head and eye position changing), 4) animated avatar alternated its gaze direction to the left and to the right (head and eye position), 5) environment with 4 animated avatars all of which change gaze and one of which is the target of attention. We found a late (> 300 ms) neurophysiological oddball correlate for all conditions irrespective of their complexity as assessed by repeated measures ANOVA. We attempted single-trial detection of this signal with automatic classifiers and obtained a significant balanced accuracy classification of around 79%, which is noteworthy given the amount of scene complexity. Lateralization analysis showed a specific right lateralization only for more complex realistic social scenes. In sum, complex ecological animations with social content elicit neurophysiological events which can be characterized even at the single-trial level. These signals are right lateralized. These finding paves the way for neuroscientific studies in affective neuroscience based on complex social scenes, and given the detectability at the single trial level this suggests the feasibility of brain computer interfaces that can be applied to social cognition disorders such as autism.
Accessibility: Document exists in file
Language:
eng
Author:
Amaral, C.
Secondary author(s):
Simões, M., Castelo-Branco, M.
Document type:
Article
Number of reproductions:
1
Reference:
Amaral, C., Simões, M., & Castelo-Branco, M. (2015). Neural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized. PLoS ONE, 10(3): e0121970. https://doi.org/10.1371/journal.pone.0121970
2-year Impact Factor: 3.057|2015
Times cited: 13|2025-02-10
Indexed document: Yes
Quartile: Q1
Keywords: Autism / Social cognition / Vision

Neural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized

Neural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized
DocumentNeural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-132
Location: Arquivo PCA - Pasta 11/2012
Title:
132 - A direct test of the binding by synchrony hypothesis in humans: the neural correlates of coherent object perception
Duration: 2013-11 - 2016-01
Researcher(s):
Miguel Castelo-Branco, Maria Ribeiro, João Duarte, Gabriel Costa
Institution(s): IBILI, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress reports
Final report
Article
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Ribeiro, M., Duarte, J., Costa, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Perception / Brain structure and function

Reference code: PT/FB/BL-2012-132.08
Location: Arquivo PCA - Pasta 11/2012
Title:
Neural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized
Publication year: 2015
URL:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121970
Abstract/Results: ABSTRACT:
Classification of neural signals at the single-trial level and the study of their relevance in affective and cognitive neuroscience are still in their infancy. Here we investigated the neurophysiological correlates of conditions of increasing social scene complexity using 3D human models as targets of attention, which may also be important in autism research. Challenging single-trial statistical classification of EEG neural signals was attempted for detection of oddball stimuli with increasing social scene complexity. Stimuli had an oddball structure and were as follows: 1) flashed schematic eyes, 2) simple 3D faces flashed between averted and non-averted gaze (only eye position changing), 3) simple 3D faces flashed between averted and non-averted gaze (head and eye position changing), 4) animated avatar alternated its gaze direction to the left and to the right (head and eye position), 5) environment with 4 animated avatars all of which change gaze and one of which is the target of attention. We found a late (> 300 ms) neurophysiological oddball correlate for all conditions irrespective of their complexity as assessed by repeated measures ANOVA. We attempted single-trial detection of this signal with automatic classifiers and obtained a significant balanced accuracy classification of around 79%, which is noteworthy given the amount of scene complexity. Lateralization analysis showed a specific right lateralization only for more complex realistic social scenes. In sum, complex ecological animations with social content elicit neurophysiological events which can be characterized even at the single-trial level. These signals are right lateralized. These finding paves the way for neuroscientific studies in affective neuroscience based on complex social scenes, and given the detectability at the single trial level this suggests the feasibility of brain computer interfaces that can be applied to social cognition disorders such as autism.
Accessibility: Document does not exist in file
Language:
eng
Collection: ( ;
BL-2012-133.08)
Author: Amaral, C.
Secondary author(s):
Simões, M., Castelo-Branco, M.
Document type:
Article-d
Number of reproductions:
1
Reference:
Amaral, C., Simões, M., & Castelo-Branco, M. (2015). Neural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized. PLoS ONE, 10(3): e0121970. https://doi.org/10.1371/journal.pone.0121970
2-year Impact Factor: 3.057|2015
Times cited: 13|2025-02-10
Indexed document: Yes
Quartile: Q1
Keywords: Autism / Social cognition / Vision
DocumentAbnormal neuronal oscillations in ASD are specific to stimuli requiring holistic processing 2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-132
Location: Arquivo PCA - Pasta 11/2012
Title:
132 - A direct test of the binding by synchrony hypothesis in humans: the neural correlates of coherent object perception
Duration: 2013-11 - 2016-01
Researcher(s):
Miguel Castelo-Branco, Maria Ribeiro, João Duarte, Gabriel Costa
Institution(s): IBILI, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress reports
Final report
Article
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Ribeiro, M., Duarte, J., Costa, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Perception / Brain structure and function

Reference code: PT/FB/BL-2012-132.17
Location: Arquivo PCA - Pasta 11/2012
Title:
Abnormal neuronal oscillations in ASD are specific to stimuli requiring holistic processing
Publication year: 2017
URL:
https://ww5.aievolution.com/hbm1701/index.cfm?do=abs.viewAbs&abs=2167
Abstract/Results: ABSTRACT:
INTRODUCTION:
Autism spectrum disorder (ASD) subjects have impaired face recognition and emotional expression identification (Greimel et al. 2014). Some studies have revealed impaired gamma-band responses with reduced coherence for a broad range of perceptual and visuomotor tasks and in particular deficits in simple sensory and complex cognitive tasks requiring holistic processing (Richard 2012; Sun et al. 2012; Buard et al. 2013). Emerging evidence suggests that the deficits in ASD may be related to sensory integration problems and can be explained by abnormal neuronal oscillations (Peiker et al. 2015). We add to previous work by asking whether changes in gamma-band power and synchrony are either specific to stimuli requiring sensory integration or a more general deficit not only related to holistic processes.
METHODS:
We investigated the neural correlates of these phenomena by measuring EEG in high-functioning adults with ASD (n=9; age M=23.1 years; SD=7.04; Full scale IQ>70) and healthy controls (n=16; age M=23.4 years; SD=5.06), during a face decision task. Subjects had a two choice decision (is it a face? Yes or No). The task included a comprehensive set of photographic, schematic and Mooney (which can only be processed holistically) upright and inverted faces, and scrambled images. The 40 channel NuAmps system (Compumedics, Neuroscan) with a 1kHz sampling rate was used. Data were analyzed offline in the time-frequency domain (EEGLAB toolbox v13.6.5b) and a bootstrap approach was applied for statistical comparison of groups. In a subset (n=5) of ASD patients we also acquired Magnetic Resonance Neurospectroscopy (3T Siemens Trio) in a 3x3x3cm voxel located in the bilateral medial prefrontal cortex using MEGA-PRESS for quantification of gamma-aminobutyric acid (GABA) (inhibition) and glutamate (excitation). MRS data was quantified using LCModel software and in-house developed software was used for correction of metabolites concentration for the CSF content of the voxel. The spearman correlation was computed between metabolites concentration and power parameters.
RESULTS:
Behaviorally, ASD and healthy controls were performance matched. Time-frequency data analysis revealed a burst of activity around 200ms replicating previous EEG results with Mooney stimuli (Rodriguez et al. 1999). We found significant differences between groups for three main categories of frequency bands (p<0.001 with bootstrap 1000, 95%). ASD have increased power for the lower band 10-30Hz (Mooney faces upright and inverted faces conditions) but decreased power at 30-45Hz and 55-80Hz (Mooney faces upright and inverted) in comparison to controls. That increase in power was accompanied by a decrease in synchrony for the 10-30Hz band. Interestingly we found a positive correlation (r=0.829, p=0.042) between GABA/Glutamate ratio and power of ambiguous conditions at 30-45Hz in patients.
CONCLUSIONS
We found that abnormal oscillations are specific of conditions requiring holistic integration and thus may be a consequence of cortical E-I (excitation vs inhibition) imbalance and their impact on binding mechanisms and might ultimately constitute a new construct of a biomarker for ASD.
Accessibility: Document does not exist in file
Language:
eng
Author:
Castelhano, J.
Secondary author(s):
Tavares, P., Mouga, S., Pereira, A., Giomar, O., Castelo-Branco, M.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Castelhano, J., Tavares, P., Mouga, S., Pereira, A., Giomar, O., & Castelo-Branco, M. (2017, June). Abnormal neuronal oscillations in ASD are specific to stimuli requiring holistic processing. Poster presented at the 2017 Annual Meeting of the Human Brain Mapping, Vancouver, Canada. Abstract retrieved at https://ww5.aievolution.com/hbm1701/index.cfm?do=abs.viewAbs&abs=2167
Indexed document: No
Keywords: Autism / Electroencephalogram (EEG) / GABA
DocumentHow do hypothalamic nonapeptides shape youth’s sociality? A systematic review on oxytocin, vasopressin and human socio-emotional development2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-158
Location: Arquivo PCA - Pasta 28/2012
Title:
158 - Neuroendocrine underpinnings of social bonds to parents and peers in preschool children. Oxytocin and Cortisol on adopted children and non-adopted controls
Duration: 2013-09 - 2018-10
Researcher(s):
Nuno Manuel Correia Torres, Manuela Veríssimo, Antonio J. Santos, Jaak Panksepp, Lígia Monteiro, Leandra Marília Marques Coelho
Institution(s): Research Group on Developmental Psychology of UIPCDE (Unidade de Investigação em Psicologia Cognitiva, do Desenvolvimento e da Educação) of ISPA-IU, Lisboa (Portugal) and Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Neuroscience Program. Washington State University (USA)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
1 Article
Language: eng
Author:
Torres, N.
Secondary author(s):
Veríssimo, M., Santos, A., Panksepp, J., Monteiro, L., Coelho, L.
Number of reproductions:
1
Keywords:
Psychophysiology / Affective and social behavior / Attachment / Developmental psychology / Cognitive development / Psychosocial development / Psychoneuroimmunology / Endocrinology / Biopsychological problems / Mental health

Reference code: PT/FB/BL-2012-158.02
Location: Arquivo PCA - Pasta 28/2012
Title:
How do hypothalamic nonapeptides shape youth’s sociality? A systematic review on oxytocin, vasopressin and human socio-emotional development
Publication year: 2018
URL:
https://www.sciencedirect.com/science/article/pii/S0149763417308850?via%3Dihub
Abstract/Results: ABSTRACT:
The hypothalamic nonapeptides oxytocin and vasopressin are important modulators of socio-affective behaviours in a wide variety of animal species, including humans. Nevertheless, there is little research addressing their possible roles on socio-affective dimensions of human behaviour across development, during which considerable behavioural and physiological change occurs. Questions still remain about the extent to which findings from adults may directly apply to earlier phases of human development. In this article, we systematically summarize and discuss all existing studies investigating the developmental association of endogenous levels of hypothalamic neuropeptides oxytocin and vasopressin with human social behaviour or on its disruption in paediatric populations. Evidence is sparse insofar as there are still relatively few developmental studies and limited due to correlational research designs and unreliability of methods currently used for neuropeptide measurements in biological fluids. The findings to date generally converge with adult evidence, but also suggest that important differences between age stages may exist. Further studies focusing these differences may prove critical for informing drug development for socio-affective deficits in paediatric populations.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Torres, N.
Secondary author(s):
Martins, D., Santos, A. J., Prata, D., Veríssimo, M.
Document type:
Article
Number of reproductions:
1
Reference:
Torres, N., Martins, D., Santos, A. J., Prata, D., & Veríssimo, M. (2018). How do hypothalamic nonapeptides shape youth’s sociality? A systematic review on oxytocin, vasopressin and human socio-emotional development. Neuroscience & Biobehavioral Reviews, 90, 309-331. https://doi.org/10.1016/j.neubiorev.2018.05.004
2-year Impact Factor: 8.002|2018
Times cited: 33|2025-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Autism / Neurodevelopment disorders / Oxytocin / Paediatric populations / Social cognition / Vasopressin
DocumentA role for preparatory midfrontal theta in autism as revealed by a high executive load brain–computer interface reverse spelling task2025

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-306
Location: BF-GMS
Title:
306 - The neural circuitry underlying error monitoring during social cognition
Duration: 2019-10 - 2022-09
Researcher(s):
Teresa Sousa, Miguel Castelo-Branco, João Castelhano, Verónica Figueiredo, Andreia Pereira
Institution(s): Institute for Nuclear Sciences Applied to Health - ICNAS, University of Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Sousa, T.
Secondary author(s):
Castelo-Branco, M., Castelhano, J., Figueiredo, V., Pereira, A.
Number of reproductions:
1
Keywords:
Error metacognition / Social error monitoring / Cognitive control / Electroencephalogram (EEG) / Functional magnetic resonance imaging (fMRI) / Psychophysiology

Reference code: PT/FB/BL-2018-306.06
Location: BF-GMS
Title:
A role for preparatory midfrontal theta in autism as revealed by a high executive load brain–computer interface reverse spelling task
Publication year: 2025
URL:
https://doi.org/10.1038/s41598-025-00670-7
Abstract/Results: ABSTRACT:
Midfrontal theta oscillations have been linked to executive function, yet their role in autism - where this function is often compromised - remains unclear. We hypothesized that preparatory increases in theta power may help normalize performance in autism. To test this, we used a challenging interactive executive function task designed to impose a high working memory load and require constant error monitoring. An electroencephalogram (EEG)-based brain–computer interface (BCI) was used to maximize cognitive load and engagement. Neural activity from autistic and non-autistic adults was compared while participants were asked to mentally reverse pseudowords (engaging working memory) and write them using the BCI, which provided real-time performance feedback (maximizing error monitoring). The study focused on theta power modulation during the preparatory (pre-response) and feedback (post-response) periods but also explored the role of posterior alpha oscillations. Results showed similar task performance between groups, but distinct recruitment of brain resources, particularly during the preparatory period. The finding of an increased preparatory theta in autism favors the hypothesis of compensatory recruitment of cognitive control and attentional mechanisms to achieve accurate results.
Accessibility: Document exists in file
Language:
eng
Author:
Dias, C.
Secondary author(s):
Sousa, T., Cruz, A., Costa, D., Mouga, S., Castelhano, J., Pires, G., Castelo-Branco, M.
Document type:
Article
Number of reproductions:
1
Reference:
Dias, C., Sousa, T., Cruz, A., Costa, D., Mouga, S., Castelhano, J., Pires, G., & Castelo-Branco, M. (2025). A role for preparatory midfrontal theta in autism as revealed by a high executive load brain–computer interface reverse spelling task. Scientific Reports, 15, 16671. https://doi.org/10.1038/s41598-025-00670-7
2-year Impact Factor: 3.8|2023
Impact factor notes: Impact factor not available yet for 2025
Times cited: 0|2025-06-12
Indexed document: Yes
Quartile: Q1
Keywords: Autism / Executive function / Midfrontal theta / Error monitoring / EEG-based BCI

A role for preparatory midfrontal theta in autism as revealed by a high executive load brain–computer interface reverse spelling task

A role for preparatory midfrontal theta in autism as revealed by a high executive load brain–computer interface reverse spelling task