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DocumentClinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.02
Location: Arquivo PCA - Pasta 3/2000
Title:
Clinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study
Publication year: 2004
URL:
http://www.sciencedirect.com/science/article/pii/S1525505003003950
Contents: http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=160&SID=V1leIhH4ysTdNpr3OrX&page=1&doc=1
Abstract/Results: ABSTRACT:
We investigated the effect of galvanic skin response (GSR) biofeedback training on seizure frequency in patients with treatment-resistant epilepsy. Eighteen patients with drug-refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n=10) or to a sham control biofeedback group (n=8). Biofeedback training significantly reduced seizure frequency in the active biofeedback group (P=0.017), but not the control group (P>0.10). This was manifest as a significant between-group difference in seizure reduction (P=0.01). Furthermore, there was a correlation between degree of improvement in biofeedback performance and reduction of seizure frequency (?=0.736, P=0.001), confirming that the effect of biofeedback treatment was related to physiological change. Our findings highlight the potential therapeutic value of GSR biofeedback in reducing seizure frequency in patients with drug-resistant epilepsy.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Fenwick, P., Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Goldstein, L., Fenwick, P., & Trimble, M. R. (2004). Clinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study. Epilepsy & Behaviour, 5(2), 216-223. https://doi.org/10.1016/j.yebeh.2003.12.003
2-year Impact Factor: 1.630|2004
Times cited: 77|2024-02-05
Indexed document: Yes
Quartile: Q2
Keywords: Galvanic skin response (GSR) / Biofeedback / Randomized controlled study / Drug refractory epilepsy / Seizure reduction

Clinical efficacy of biofeedback treatment on reducing seizures in adult epilepsy: a preliminary randomized controlled study

Clinical efficacy of biofeedback treatment on reducing seizures in adult epilepsy: a preliminary randomized controlled study
DocumentActivity inventromedial prefrontal cortex covaries with sympathetic skin conductance level (SCL): a physiological account of a "default mode" of brain function2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.04
Location: Arquivo PCA - Pasta 3/2000
Title:
Activity inventromedial prefrontal cortex covaries with sympathetic skin conductance level (SCL): a physiological account of a "default mode" of brain function
Publication year: 2004
URL:
http://www.sciencedirect.com/science/article/pii/S1053811904000540
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=15&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
We examined neural activity related to modulation of skin conductance level (SCL), an index of sympathetic tone, using functional magnetic resonance imaging (fMRI) while subjects performed biofeedback arousal and relaxation tasks. Neural activity within the ventromedial prefrontal cortex (VMPFC) and the orbitofrontal cortex (OFC) covaried with skin conductance level (SCL), irrespective of task. Activity within striate and extrastriate cortices, anterior cingulate and insular cortices, thalamus, hypothalamus and lateral regions of prefrontal cortex reflected the rate of change in electrodermal activity, highlighting areas supporting transient skin conductance responses (SCRs). Successful performance of either biofeedback task (where SCL changed in the intended direction) was associated with enhanced activity in mid-OFC. The findings point to a dissociation between neural systems controlling basal sympathetic tone (SCL) and transient skin conductance responses (SCRs). The level of activity in VMPFC has been related to a default mode of brain function and our findings provide a physiological account of this state, indicating that activity within VMPFC and OFC reflects a dynamic between exteroceptive and interoceptive deployment of attention.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D., Featherstone, E., Trimble, M. R., Dolan, R. J.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Critchley, H. D., Featherstone, E., Trimble, M. R., & Dolan, R. J. (2004). Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level: a physiological account of a "default mode" of brain function. NeuroImage, 22(1), 243-251. https://doi.org/10.1016/j.neuroimage.2004.01.019
2-year Impact Factor: 4.869|2004
Times cited: 320|2024-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Skin conductance / Functional magnetic resonance imaging (fMRI) / Biofeedback
DocumentInfluence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.05
Location: Arquivo PCA - Pasta 3/2000
Title:
Influence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy
Publication year: 2004
URL:
http://www.google.pt/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&cad=rja&ved=0CDAQFjAA&url=http%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fdownload%3Fdoi%3D10.1.1.124.795%26rep%3Drep1%26type%3Dpdf&ei=tEjNUcjKIfSR7Aab1oBg&usg=AFQjCNHjj37kSx3p2CPlzuuH7h6K96Xs-w&sig2=PbDr5s-sOh4IwUUKET5uUw&bvm=bv.48572450,d.ZWU
Abstract/Results: ABSTRACT:
Negative amplitude shifts of cortical potential are related to seizure activity in epilepsy. Regulation of the cortical potential with biofeedback has been successfully used to reduce the frequency of some patients’ seizures. Although such behavioural treatments are increasingly popular as an alternative to pharmacotherapy, there has been no investigation of the mechanisms that might bridge the behavioural index of peripheral autonomic activity and the central regulation of arousal. Galvanic Skin Response (GSR) is a sensitive measurement of autonomic arousal and physiological state which reflects one’s behaviour. Thus we investigated the effect of peripheral autonomic modulation on cortical arousal with the future intention of using GSR biofeedback as a therapeutic treatment for epilepsy. The cortical negative potential was induced using the paradigm called Contingent Negative Variation (CNV) and measured in different physiological states. A high skin resistance state (reflecting a state of relaxation) and a low skin resistance state (reflecting a state of arousal), were engendered by two opposing procedures of GSR biofeedback. The CNV negative potential, acting as an index of cortical excitation, was significantly greater in amplitude at high levels of skin resistance (relaxed state) than at low levels of skin resistance (aroused state). Our results suggest an inverse relationship between a peripheral measure of autonomic arousal and an index of cortical arousal, the CNV. Moreover, we demonstrate modulation of this arousal-related potential by a behavioural intervention, indicating a potential therapeutic use of arousal biofeedback using GSR in the management of treatment-resistant epilepsy.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Critchley, H. D., Fenwick, P.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Goldstein, L., Critchley, H. D., & Fenwick, P. (2004). Influence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy. Epilepsy Research, 58(2-3), 185-193. https://doi.org/10.1016/j.eplepsyres.2004.02.004
2-year Impact Factor: 2.897|2004
Times cited: 39|2024-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Contingent negative variation (CNV) / Galvanic Skin Response (GSR) / Biofeedback

Influence of sympathetic autonomic arousal on contingent negative variation: implications for a therapeutic behavioural intervention in epilepsy

Influence of sympathetic autonomic arousal on contingent negative variation: implications for a therapeutic behavioural intervention in epilepsy
DocumentChanges in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.06
Location: Arquivo PCA - Pasta 3/2000
Title:
Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy
Publication year: 2009
URL:
http://www.psychosomaticmedicine.org/content/71/1/84.full.pdf
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=19&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
OBJECTIVES:
To examine the immediate and sustained effects of volitional sympathetic modulation, using galvanic skin response (GSR) biofeedback training on cortical excitability in patients with drug-resistant epilepsy.
METHODS:
Ten patients undertook 12 sessions of GSR biofeedback training over 1 month, during which they were trained to increase sympathetic arousal, using GSR biofeedback. Contingent negative variation (CNV) (a slow cortical potential reflecting cortical arousal and excitability) and the related post imperative negative variation (PINV) were quantified before and after biofeedback treatment.
RESULTS:
A significant reduction in CNV amplitude was observed in both the short-term (within the first session, after 10 minutes of GSR biofeedback) and long-term (sustained after 12 training sessions). Specifically, the change in baseline CNV amplitude after the 12 training sessions correlated with a percentage reduction in seizure frequency. Furthermore, changes in baseline amplitude of the PINV also correlated with seizure reduction.
CONCLUSIONS:
Our findings demonstrate that behavioral enhancement of peripheral sympathetic tone (GSR) is associated with modulation of indices of cortical excitability. Moreover, GSR biofeedback training over repeated sessions was associated with a chronic baseline reduction in slow cortical potentials and concurrent therapeutic improvement.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D., Rothwell, J. C., Duncan, J. S., Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Critchley, H. D., Rothwell, J. C., Duncan, J. S., & Trimble, M. R. (2009). Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy. Psychosomatic Medicine, 71(1), 84-92. https://doi.org/10.1097/PSY.0b013e31818f667c
2-year Impact Factor: 4.236|2009
Times cited: 26|2024-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Biofeedback / Galvanic skin response (GSR) / Contingent negative variation (CNV) / Slow cortical potentials / Post imperative negative / Epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy
DocumentNovel application of electrodermal biofeedback to neurological disorder: therapeutic and neural mechanisms2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.08
Location: Arquivo PCA - Pasta 3/2000
Title:
Novel application of electrodermal biofeedback to neurological disorder: therapeutic and neural mechanisms
Publication year: 2007
Accessibility:
Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D.
Document type:
Book chapter
Number of reproductions:
1
Reference:
Nagai, Y., & Critchley, H. D. (2007). Novel therapeutic application of Galvanic Skin Response (GSR) biofeedback to a neurological disorder: Mechanisms underlying biofeedback in epilepsy management. In H. L. Puckhaber(Ed.), New research in biofeedback (pp. 1-31). New York, NY: Nova Publisher.
Indexed document: No
Keywords: Psychophysiology / Neurological disorder / Biofeedback
DocumentFinal report - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-163
Location: Arquivo PCA - Pasta 7/2004
Title:
163 - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects
Duration: 2005-01 - 2006-04
Researcher(s):
Martijn Arns, Wytze van der Zwaag, Erica Heesen, Rien Breteler
Institution(s): Brain Resource Company B.V., Nijmegen (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report (2 copies)
Article
Master's thesis
Language: eng
Author:
Arns, M.
Secondary author(s):
Van der Zwaag, W., Heesen, E., Breteler, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning

Reference code: PT/FB/BL-2004-163.01
Location: Arquivo PCA - Pasta 7/2004
Title:
Final report - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects
Publication year: 2006
URL:
http://www.bial.com/imagem/Bolsa16304_03122012.pdf
Abstract/Results: RESULTS:
The results show that GSR biofeedback, as compared to SCP Neurofeedback, is easier to learn which confirms the findings from Nagai et al. (2004). Furthermore, SCP-trained subjects show the biggest SCP differentiation as compared to GSR-trained people and GSRtrained people show the biggest GSR differentiation as compared to the SCP trained, which confirms that the primary learning effect can be found in the modality being trained; e.g. if subjects are trained on their SCP, then the differentiation of the SCP is also biggest and increases with training time. No clear differentiation effects were found for the ‘other’ modality suggesting that training on GSR does not directly affect or modulate SCP’s and vice versa as measured with this differentiation method.
No consistent differences were found in the pre- and post QEEG’s for both groups. This is in agreement with the study from Kotchouby et al. (1999) who also failed to report consistent changes in the QEEG after SCP Neurofeedback.
The individual correlation analysis revealed no correlations for the GSR Biofeedback group. However, for the SCP feedback group significant correlations were found for both the positivity and negativity conditions. The significant correlations seem to suggest that successful SCP trials are associated with increased arousal. These correlations are probably not related to a functional relation between SCP regulation and GSR regulation – which was the hypothesis to be investigated in this study. In such a case SCP positivity would be related to increased arousal, whereas SCP negativity would be related to decreased arousal or vice versa. Our results suggest increased GSR arousal being related to both training conditions, suggesting a non-specific arousal effect related to degree of success.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Arns, M.
Secondary author(s):
Heesen, E., Spronk, D., Kleinnijenhuis, M., Van Luijtelaar, G.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Cognition / Biofeedback / Neurofeedback

Final report - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects

Final report - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects
DocumentHigh performance REG array with simultaneous Read-Out - Exploration of a new REG design, involving self-selective amplification and EEG triggered read-out for PK studies2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-074
Location: Arquivo PCA - Pasta 11/2004
Title:
074 - High performance REG array with simultaneous read-out: Exploration of a new REF design, involving self-selective amplification and EEG triggered read-out for PK studies
Duration: 2005-01 - 2007-07
Researcher(s):
Harald Walach, Tilmann Faul, Matthias Braeunig
Institution(s): Institute for Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg (Germany)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report (English and German version)
1 Conference proceedings
1 Poster
Language: eng / ger
Author:
Walach, H.
Secondary author(s):
Faul, T., Braeunig, M.
Number of reproductions:
2
Keywords:
Parapsychology / Assessment tools / Psychokinesis (PK)

Reference code: PT/FB/BL-2004-074.04
Location: Arquivo PCA - Pasta 11/2004
Title:
High performance REG array with simultaneous Read-Out - Exploration of a new REG design, involving self-selective amplification and EEG triggered read-out for PK studies
Publication year: 2006
URL:
http://www.bial.com/imagem/1178809516livroactas.pdf
Abstract/Results: ABSTRACT:
OBJECTIVES:
Construction of a physical random event generator (REG) with fast parallel processing based on FPGA
technology, achieving local coupling with the environment through an explicit trigger-feedback loop. To deliberately influence the outcome of random bit generation by means of internal and external trigger signals, while still maintaining the null-hypothesis. We will argue in favor for systemic closure as the key to unify the views of influence and data selection theories.
METHODS:
Electronic transistor noise is amplified and digitized, oscillating randomly between two states, a frequency divider assures exact 50% unbiased duty cycle at a mean frequency about 1.3 MHz. Comparison of three triggering modes: Internal triggers drawn from the output bit sequence itself, external EEG modulated triggers, and fixed frequency triggers. Sampling is realized in 4-5 channels at a mean frequency about 1 kHz for trials of 200 bit samples drawn in parallel from the stream, hits and transitions are counted. Acoustic feedback is given by ascending and descending tones based on the cumulative deviation score, while a participant is asked to keep an intention of increasing, or lowering the tones.
RESULTS:
15 human subjects participated in experiments each comprising 13 sets of combinations of trigger modes and intention conditions. Each set generated 1.2 MBits of data in 4 channels. Autocorrelation is less than 1%. Control runs satisfy the normality condition imposed to maintain the null-hypothesis. Larger deviations
were observed in sets where participants were allowed a new method of partially inverting the meaning of hits and misses (M-switch), indicating a pre-cognitive factor present.
CONCLUSION:
It seems that significant hit rates can be achieved by operationally closing a system made of an entropy source and a conscious observer, suggesting that the triggered REG is more sensitive to local interaction with the environment than more conventional setups. The main ingredient is an explicit trigger-feedback loop that
involves a participant who attributes meaning to a sequence of events.
Accessibility: Document exist in file (poster)
Copyright/Reproduction:
By permission
Language:
eng
Notes:
Abstract and respective poster in attachment
Author: Walach, H.
Secondary author(s):
Faul, T., Bösch, H., Braeunig, M.
Document type:
Conference abstract
Number of reproductions:
2
Reference:
Walach, H., Faul, T., Bösch, H., & Braeunig, M. (2006). High performance REG array with simultaneous Read-
Out - Exploration of a new REG design, involving self-selective amplification and EEG triggered read-out for PK studies. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 6th Symposium of Fundação Bial (pp. 269-270). Porto: Fundação Bial.
Indexed document: No
Keywords: Triggered REG / Meaning / Biofeedback / Operational closure / Parapsychology

Abstract

Abstract

Poster

Poster
DocumentRefining the methodology of alpha electroencephalographic biofeedback and exploring its effect on cognition and mood2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-045
Location: Arquivo PCA - Pasta 10/2008
Title:
045 - Refining the methodology of alpha electroencephalographic biofeedback and exploring its effect on cognition and mood
Duration: 2009-02 - 2012-04
Researcher(s):
David Vernon, Soren Andersen, Neil Rutterford, Marcia Pasqualini, Olga Bazanova
Institution(s): Dept. of Applied Social Sciences, Canterbury Christ Church University (UK), University of East Anglia Norwich (UK), Dept. of Psychology, Avila University, Kansas City (USA), Siberian Branch of the Russian Medical Academy, State Institute for Molecular Biology and Biophysics, Nonvosibirsk (Russia)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Article
Language: eng
Author:
Vernon, D.
Secondary author(s):
Andersen, S., Rutterford, N., Pasqualini, M., Bazanova, O.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning

Reference code: PT/FB/BL-2008-045.05
Location: Arquivo PCA - Pasta 10/2008
Title:
Refining the methodology of alpha electroencephalographic biofeedback and exploring its effect on cognition and mood
Publication year: 2012
URL:
http://www.bial.com/imagem/Bial%20Sonhos%20Miolo_Total%20Bolsas.pdf
Abstract/Results: ABSTRACT:
Objectives: EEG biofeedback has been used to help train individuals to learn to consciously control
certain aspects of their brainwave activity. However, a number of methodological questions
remain concerning the nature of such training which limits our understanding of the process and
the possible effectiveness of the technique. Hence the aim of this project was to examine more
closely the nature of such training by using distinct reward thresholds, incorporating an equal
contact mock feedback control group and performing follow-up measures to examine the possible
long-term effects.
Methods: Using a standard pre/post intervention design we recruited 96 participants from four
institutions (CCCU, RAMS, UEA and AU). Participants initially completed a range of cognitive
(Conceptual Span Task; Mental Rotation Task, Alternative Uses Task) and mood measures (Profile
Of Mood States, STAI, BIS/BAS). They were then randomly allocated to either a real or mock
feedback condition utilising either a fixed low, medium, high or non-fixed variable reward
threshold. All participants then completed 10 training sessions, approximately twice per week,
with the aim to increase the amplitude of their alpha (8-12Hz) EEG rhythm. On completion of the
training participants again completed the cognitive and mood measures, and again at follow-up
after a delay of approx 4 wks.
Results: Initial analyses showed no evidence of a clear change in the EEG for those completing the
biofeedback training. In addition, the differential reward thresholds had no effect on changes in
EEG. A more fine tuned analysis, focusing on the effects of each institution, found that the
biofeedback training enhanced the peak frequency, width and power in the individual upper alpha
range (10-12Hz) but only for those with a low resting baseline frequency (<10Hz) and only in the
Russian (RAMS) sample.
Conclusions: It would seem clear that the training paradigm adopted here was not effective in
eliciting clear changes in the EEG.
Discussion: The project was less successful than anticipated in identifying potential methodological
factors that could positively influence learning. Nevertheless, the pattern of findings not only
provides a reasonable indication of what does not work but also highlights possible avenues for
further exploration. For instance, the motivation level of the individual, identifying a possible
distinction between responders and learners and using resting peak alpha levels as a marker for
change.
Accessibility: Document does not exist in file
Language:
eng
Author:
Vernon, D.
Secondary author(s):
Andersen, S., Rutterford, N., Pasqualini, M., Bazanova, O.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Vernon, D., Andersen, S., Rutterford, N., Pasqualini, M., & Bazanova, O. (2012). Refining the methodology of alpha electroencephalographic biofeedback and exploring its effect on cognition and mood. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 9th Symposium of Fundação Bial (pp. 22-23/63). Porto: Fundação Bial.
Indexed document: No
Keywords: Alpha / Electroencephalography / Biofeedback / Neurofeedback

Novo ficheiro

Novo ficheiro
DocumentLong-term effects of electrodermal biofeedback training on seizure control in patients with drug-resistant epilepsy: Two case reports2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.11
Location: Arquivo PCA - Pasta 3/2000
Title:
Long-term effects of electrodermal biofeedback training on seizure control in patients with drug-resistant epilepsy: Two case reports
Publication year: 2014
URL:
http://www.epires-journal.com/article/S0920-1211(13)00258-1/abstract
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=25&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
We report data from two patients, followed over 3 years after electrodermal biofeedback treatment. Patients were trained three times each week for four weeks to increase their sympathetic arousal using electrodermal biofeedback. This treatment was directed at enabling the patients to change their psychophysiological state as a countermeasure to prevent seizures. Both patients voluntarily kept a record of seizure frequency over the year preceding the treatment and continued to record their seizures for up to 3 years after the termination of biofeedback treatment. Both patients showed a marked reduction in seizure frequency (54.9% and 59.8%) during the month of biofeedback treatment. This improvement was maintained over the subsequent years. We highlight the therapeutic potential of biofeedback interventions that enable patients to volitionally control their state of physiological arousal in the management of drug-resistant epilepsy.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Nagai, Y., & Trimble, M. R. (2014). Long-term effects of electrodermal biofeedback training on seizure control in patients with drug-resistant epilepsy: Two case reports. Epilepsy Research, 108(1), 149-152. https://doi.org/10.1016/j.eplepsyres.2013.10.004
2-year Impact Factor: 2.015|2014
Times cited: 16|2024-02-02
Indexed document: Yes
Quartile: Q3
Keywords: Biofeedback / Electrodermal activity (EDA) / Drug resistant epilepsy
DocumentBiofeedback and epilepsy2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.12
Location: Arquivo PCA - Pasta 3/2000
Title:
Biofeedback and epilepsy
Publication year: 2011
URL:
http://link.springer.com/article/10.1007%2Fs11910-011-0201-3
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=27&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
Biofeedback is a noninvasive behavioral treatment that enables a patient to gain volitional control over a physiological process. As a treatment for epilepsy, biofeedback interventions were explored from as early as the 1970s, concentrating on sensory motor rhythm (SMR) as a neurophysiologic parameter. Whereas SMR biofeedback aims to modulate frequency components of the electroencephalography (EEG), slow cortical potential (SCP) biofeedback (which was introduced in the 1990s) focuses on the regulation of the amplitude of cortical potential changes (DC shift). In its application to epilepsy, biofeedback using galvanic skin response (GSR), an electrodermal measure of sympathetic activity, is a relatively new cost-effective methodology. The present article first reviews biofeedback using SMR and SCP, for which efficacy and neural mechanisms are relatively well characterized. Then recent data regarding promising applications of GSR biofeedback will be introduced and discussed in detail.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y. (2011). Biofeedback and epilepsy. Current Neurology and Neuroscience Reports, 11(4), 443-450. https://doi.org/10.1007/s11910-011-0201-3
2-year Impact Factor: 3.455|2011
Times cited: 20|2024-02-01
Indexed document: Yes
Quartile: Q1
Keywords: Biofeedback / Volitional control / Sensory motor rhythm (SMR) / Slow cortical potentials (SCPs) / Galvanic skin response (GSR)
DocumentSkin conductance feedback meditation: Evaluation of a novel physiology-assisted meditation style2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-402
Location: BF-GMS
Title:
402 - Skin Conductance Feedback Meditation (SCFM) - Exploring the role of skin conductance in meditative practice
Duration: 2016-03
Researcher(s):
Thilo Hinterberger
Institution(s): Department of Psychosomatic Medicine, Clinic of the University of Regensburg (Germany)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Language: eng
Notes:
This project is still in progress
Author: Hinterberger, T.
Number of reproductions:
3
Keywords:
Meditation / Mindfulness / Skin Conductance / Feedback / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2014-402.02
Location: BF-GMS
Title:
Skin conductance feedback meditation: Evaluation of a novel physiology-assisted meditation style
Publication year: 2018
URL:
https://www.karger.com/Article/Abstract/489342
Abstract/Results: ABSTRACT:
BACKGROUND:
Mindfulness meditation (MM) can be regarded as a practice for calming the mind while the focus on their breathing can help meditators maintain a state of mindful presence. We have developed and evaluated an alternative method for reaching conscious states of pure being without the aid of a focus of attention.
MATERIALS AND METHODS:
Skin conductance feedback was provided in real-time during meditation sessions (SCFM) and the practicability of this novel approach was evaluated. Thirty participants, 15 meditation experts and 15 non-meditators, attended six sessions of meditation in three days. Four SCFM and two ordinary MM sessions were conducted. Each session was evaluated with physiological measures and a feedback questionnaire assessing subjective changes in body-related, emotional, and mental self-perception.
RESULTS:
On average, 78.3% of the participants felt more integrated and connected, 84.2% perceived themselves as more calm and balanced, and 50% felt vitalized after SCFM sessions, while only 5% or less felt more agitated or depressed after the sessions. SCFM was not significantly different from MM. The positive effect of SCFM correlated positively with mindfulness self-ratings.
CONCLUSIONS:
The study demonstrates that SCFM is a viable method for performing a satisfying and consciousness-expanding meditation session.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Hinterberger, T.
Secondary author(s):
Baierlein, F., Breitenbach, N.
Document type:
Article
Number of reproductions:
3
Percentiles:
7
Reference:
Hinterberger, T., Baierlein, F., & Breitenbach, N. (2018). Skin conductance feedback meditation: Evaluation of a novel physiology-assisted meditation style. Complementary Medicine Research, 25(5), 313-320. https://doi.org/10.1159/000489342
2-year Impact Factor: 0.805|2018
Times cited: 3|2024-02-09
Indexed document: Yes
Quartile: Q4
Keywords: Biofeedback / Mindfulness / Meditation / Skin conductance
DocumentFinal report - Skin Conductance Feedback Meditation (SCFM) - Exploring the role of skin conductance in meditative practice2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-402
Location: BF-GMS
Title:
402 - Skin Conductance Feedback Meditation (SCFM) - Exploring the role of skin conductance in meditative practice
Duration: 2016-03
Researcher(s):
Thilo Hinterberger
Institution(s): Department of Psychosomatic Medicine, Clinic of the University of Regensburg (Germany)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Language: eng
Notes:
This project is still in progress
Author: Hinterberger, T.
Number of reproductions:
3
Keywords:
Meditation / Mindfulness / Skin Conductance / Feedback / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2014-402.01
Location: BF-GMS
Title:
Final report - Skin Conductance Feedback Meditation (SCFM) - Exploring the role of skin conductance in meditative practice
Publication year: 2018
URL:
https://www.bial.com/imagem/Grant_40214.pdf
Abstract/Results: ABSTRACT:
In ordinary mindfulness meditation (MM) the focus on the breathing should help meditators maintaining a state of mindful presence. A pure state of open monitoring should not have such a focus of attention. In order to bring meditators back to the state of presence in open monitoring an externally triggered reminder would be helpful. Feedback of skin conductance (SC) related to mental distractions with emotional content could serve as such a reminder. We provided SC in real-time during meditation sessions and evaluated the practicability of this novel approach.
Thirty participants, 15 meditators and 15 non-meditators, attended six sessions of meditation in three days. Four sessions were conducted as SC feedback meditation (SCFM) sessions and two sessions as ordinary MM. Each was evaluated with physiological measures and a feedback questionnaire assessing subjective changes in body sensation, emotional condition, and mental state.
The 14 feedback items could be merged into the dimensions expansiveness and contentedness. At average, 68.3% of the participants felt more expanded and over 80% were more contented after SCFM sessions while only 3.3% felt more limited and discontented after the sessions. This result was not significantly different from MM. SCFM sessions were tested to be non-inferior to mindfulness meditations. There were no significant differences in the number of SC reactions between meditators and non-meditators and also not between MM and SCFM.
Despite finding only few significant differences in psychological and physiological measures between MM and SCFM, both methods seem to be comparably good in their effects on meditators with the advantage of SCFM that no focus of attention is required during meditation.
Accessibility: Document exists in file
Language:
eng
Author:
Hinterberger, T.
Secondary author(s):
Tamm, T., Baierlein, F., Lederer-Lug, I., Breitenbach, N.
Document type:
Final report
Number of reproductions:
3
Reference:
Hinterberger, T., Tamm, T., Baierlein, F., Lederer-Lug, I., & Breitenbach, N. (2018). Final report - Skin Conductance Feedback Meditation (SCFM) - Exploring the role of skin conductance in meditative practice.
Indexed document: No
Keywords: Mindfulness / Meditation / Skin Conductance / Biofeedback

Final report - Skin Conductance Feedback Meditation (SCFM) - Exploring the role of skin conductance in meditative practice

Final report - Skin Conductance Feedback Meditation (SCFM) - Exploring the role of skin conductance in meditative practice
DocumentGalvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-180
Location: Arquivo PCA - Pasta 20/2008
Title:
180 - Emotional influences on psychophysiological indices of focused attention and response anticipation in social anxiety: A combined neuroimaging and electroencephalographic study
Duration: 2009-10 - 2014-07
Researcher(s):
Yoko Nagai, Hugo Critchley, Marcus Gray
Institution(s): Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D. , Gray, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Biopsychological problems / Mental health / Anxiety disorders / Cognitive processes / Attention / Brain structure and function

Reference code: PT/FB/BL-2008-180.02
Location: Arquivo PCA - Pasta 20/2008
Title:
Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis
Publication year: 2019
URL:
https://www.frontiersin.org/articles/10.3389/fneur.2019.00377/full
Abstract/Results: ABSTRACT:
Objectives: Dynamic changes in psychophysiological arousal are directly expressed in the sympathetic innervation of the skin. This activity can be measured as tonic and phasic fluctuations in electrodermal activity [Galvanic Skin Response (GSR)/skin conductance]. Biofeedback training can enable an individual to gain voluntary control over this autonomic response and its central correlates. Theoretically, control of psychophysiological arousal may be harnessed as a therapy for epilepsy, to mitigate pre-ictal states. Evidence is accumulating for the clinical efficacy of GSR biofeedback training in the management of drug resistant epilepsy. In this review, we analyse current evidence of efficacy with GSR biofeedback and evaluate the methodology of each study.
Method: We searched published literature pertaining to interventional studies of GSR biofeedback for epilepsy, through MEDLINE and Cochrane databases (1950-2018). Using percentage seizure reduction as an indicator of therapeutic efficacy induced by GSR biofeedback, we used meta-analytic methods to summarize extant findings. We also compare and contrast study design with relevance to the interpretation of outcomes.
Results: Out of 21 articles retrieved for GSR/EDA/Skin conductance biofeedback, four studies were identified as interventional trials, involving 99 patients with drug-resistant epilepsy in total. Three of these studies included a control group and a positive therapeutic effect of biofeedback was reported in each of these. The difference in seizure frequency percentage (Biofeedback-Control) was between -54.4 and -74.0% with an overall weighted mean difference of -64.3% (95% CI: -85.4 to -43.2%). The response rates (proportion of patients manifesting > 50% reduction in seizure frequency) varied from 45 to 66% across studies.
Significance: This timely evaluation highlights the potential value of GSR biofeedback therapy, and informs the optimal study design of larger scale studies that are now required to more definitively establish the utility of this non-invasive, non-pharmacological interventional approach for drug-resistant epilepsy.
Accessibility: Document exists in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Jones, C. I., Sen, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
5
Reference:
Nagai, Y., Jones, C. I., & Sen, A. (2019). Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis. Frontiers in Neurology, 10: 377. https://doi.org/10.3389/fneur.2019.00377
2-year Impact Factor: 2.889|2019
Times cited: 27|2024-02-12
Indexed document: Yes
Quartile: Q2
Keywords: Epilepsy / Biofeedback / Galvanic skin response / Skin conductance / Electrodermal activity / Autonomic activity / Behavioral therapy

Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis

Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis
DocumentModulation of autonomic activity in neurological conditions: Epilepsy and Tourette Syndrome2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-180
Location: Arquivo PCA - Pasta 20/2008
Title:
180 - Emotional influences on psychophysiological indices of focused attention and response anticipation in social anxiety: A combined neuroimaging and electroencephalographic study
Duration: 2009-10 - 2014-07
Researcher(s):
Yoko Nagai, Hugo Critchley, Marcus Gray
Institution(s): Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D. , Gray, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Biopsychological problems / Mental health / Anxiety disorders / Cognitive processes / Attention / Brain structure and function

Reference code: PT/FB/BL-2008-180.03
Location: Arquivo PCA - Pasta 20/2008
Title:
Modulation of autonomic activity in neurological conditions: Epilepsy and Tourette Syndrome
Publication year: 2015
URL:
https://www.frontiersin.org/articles/10.3389/fnins.2015.00278/full
Abstract/Results: ABSTRACT:
This manuscript considers the central but neglected role of the autonomic nervous system in the expression and control of seizures in epilepsy (small) and tics in burette Syndrome (TS). In epilepsy, consideration of autonomic involvement is typically confined to differential diagnoses (e.g., syncope), or in relation to Sudden Unexpected Death in Epilepsy (SUDEP). Investigation is more limited in burette Syndrome. The role of the autonomic nervous system in the generation and prevention of epileptic seizures is largely overlooked. Emotional stimuli such as anxiety and stress are potent causes of seizures and tic activity in epilepsy and TS, respectively. This manuscript will describe a possible neural mechanism by which afferent autonomic projections linked to cognition and behavior influence central thalamo-cortical regulation, which appears to be an important means for controlling both seizure and tic activity. It also summarizes the link between the integrity of the default mode network and autonomic regulation in patients with epilepsy as well as the link between impaired motor control and autonomic regulation in patients with TS. Two neurological conditions; epilepsy and TS were chosen, as seizures and tics represent parameters that can be easily measured to investigate influences of autonomic functions. The FDA biofeedback approach is anticipated to gain a strong position within the next generation of treatment for epilepsy, as a non-invasive technique with minimal side effects. This approach also takes advantage of the current practical opportunity to utilize growing digital health technology.
Accessibility: Document exists in file
Language:
eng
Author:
Nagai, Y.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Nagai, Y. (2015). Modulation of autonomic activity in neurological conditions: Epilepsy and Tourette Syndrome. Frontiers in Neuroscience, 9: 278. https://doi.org/10.3389/fnins.2015.00278
2-year Impact Factor: 3.398|2015
Times cited: 13|2024-02-07
Indexed document: Yes
Quartile: Q2
Keywords: Biofeedback / Electrodermal activity / Sympathetic activity / Behavioral control / Epilepsy / burette Syndrome

Modulation of autonomic activity in neurological conditions: Epilepsy and Tourette Syndrome

Modulation of autonomic activity in neurological conditions: Epilepsy and Tourette Syndrome
File308 - Altered states of viscereality: Augmenting breathwork with bio-responsive virtual reality2023-09

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-308
Location: BF-GMS
Title:
308 - Altered states of viscereality: Augmenting breathwork with bio-responsive virtual reality
Duration: 2023-09
Researcher(s):
Bigna Lenggenhager, Oliver Deussen, George Fejer, Isabella Pasqualini
Institution(s): Department of Psychology, University of Konstanz (Germany)
Contents: Contents:
Application form
Correspondence
Language: eng
Author:
Lenggenhager, B.
Secondary author(s):
Deussen, O., Fejer, G., Pasqualini, I.
Number of reproductions:
3
Keywords:
Breathwork / Virtual reality / Biofeedback / Respiration / Psychophysiology and Parapsychology