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DocumentStimulus dependent neural oscillatory patterns show reliable statistical identification of Autism Spectrum Disorder in a face perceptual decision task2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-373
Location: BF-GMS
Title:
373 - Multimodal Mapping of Visual Motion Perceptual Decision: Dissecting the Role of Different Motion Integration Areas in Visual Surface Reconstruction
Duration: 2016-02 - 2017-10
Researcher(s):
Miguel de Sá e Sousa de Castelo Branco, Gabriel Nascimento Ferreira da Costa, Gilberto Silva, João Valente Duarte, Ricardo Martins
Institution(s): ICNAS - Institute for Nuclear Sciences Applied to Health, Coimbra, Portugal; IBILI - Institute for Biomedical Imaging and Life Sciences, Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Author: Castelo-Branco, M.
Secondary author(s):
Costa, G., Silva, G., Duarte, J., Martins, R.
Number of reproductions:
1
Keywords:
Motion perception / Decision-making / Perceptual Ambiguity / Decision Models / Psychophysiology

Reference code: PT/FB/BL-2014-373.18
Location: BF-GMS
Title:
Stimulus dependent neural oscillatory patterns show reliable statistical identification of Autism Spectrum Disorder in a face perceptual decision task
Publication year: 2018
URL:
https://www.sciencedirect.com/science/article/pii/S1388245718300981
Abstract/Results: ABSTRACT:
OBJECTIVE
Electroencephalographic biomarkers have been widely investigated in autism, in the search for diagnostic, prognostic and therapeutic outcome measures. Here we took advantage of the information available in temporal oscillatory patterns evoked by simple perceptual decisions to investigate whether stimulus dependent oscillatory signatures can be used as potential biomarkers in Autism spectrum disorder (ASD).
METHODS
We studied an extensive set of stimuli (9 categories of faces) and performed data driven classification (Support vector machine, SVM) of ASD vs. Controls with features based on the EEG power responses. We carried out an extensive time-frequency and synchrony analysis of distinct face categories requiring different processing mechanisms in terms of non-holistic vs. holistic processing.
RESULTS
We found that the neuronal oscillatory responses of low gamma frequency band, locked to photographic and abstract two-tone (Mooney) face stimulus presentation are decreased in ASD vs. the control group. We also found decreased time-frequency (TF) responses in the beta band in ASD after 350ms, possibly related to motor preparation. On the other hand, synchrony in the 30-45Hz band showed a distinct spatial pattern in ASD. These power changes enabled accurate classification of ASD with an SVM approach. SVM accuracy was approximately 85%. ROC curves showed about 94% AUC (area under the curve). Combination of Mooney and Photographic face stimuli evoked features enabled a better separation between groups, reaching an AUC of 98.6%.
CONCLUSIONS
We identified a relative decrease in EEG responses to face stimuli in ASD in the beta (15-30Hz; >350ms) and gamma (30-45Hz; 55-80Hz; 50-350ms) frequency ranges. These can be used as input of a machine learning approach to separate between groups with high accuracy.
SIGNIFICANCE
Future studies can use EEG time-frequency patterns evoked by particular types of faces as a diagnostic biomarker and potentially as outcome measures in therapeutic trials.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Castelhano, J.
Secondary author(s):
Tavares, P., Mouga, S., Oliveira, G., Castelo-Branco, M.
Document type:
Article
Number of reproductions:
1
Reference:
Castelhano, J., Tavares, P., Mouga, S., Oliveira, G., & Castelo-Branco, M. (2018). Stimulus dependent neural oscillatory patterns show reliable statistical identification of Autism Spectrum Disorder in a face perceptual decision task. Clinical Neurophysiology, 129(5), 981-989. https://doi.org/10.1016/j.clinph.2018.01.072
2-year Impact Factor: 3.675|2018
Times cited: 13|2025-09-17
Indexed document: Yes
Quartile: Q2
Keywords: ASD / Gamma-band / Holistic processing / EEG / Biomarker / SVM classification
DocumentInteroception and mental health: A roadmap2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-128
Location: BF-GMS
Title:
128 - Autonomic nerve recordings applied as a novel psychophysiological tool for Consciousness Science
Duration: 2015-09 - 2021-11
Researcher(s):
Hugo Dyfrig Critchley, Peter Taggart, Yrsa Sverrisdottir
Institution(s): University of Sussex: Brighton and Sussex Medical School (UK); University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Articles
Language: eng
Author:
Critchley, H. D.
Secondary author(s):
Sverrisdottir, Y.
Number of reproductions:
1
Keywords:
Microneurography / Interoception / Predictive coding / Awareness / Psychophysiology

Reference code: PT/FB/BL-2014-128.02
Location: BF-GMS
Title:
Interoception and mental health: A roadmap
Publication year: 2017
URL:
https://www.sciencedirect.com/science/article/pii/S2451902217302343
Abstract/Results: ABSTRACT:
Interoception refers to the process by which the nervous system senses, interprets, and integrates signals originating from within the body, providing a moment-by-moment mapping of the body’s internal landscape across conscious and unconscious levels. Interoceptive signaling has been considered a component process of reflexes, urges, feelings, drives, adaptive responses, cognitive and emotional experiences, highlighting its contributions to the maintenance of homeostatic functioning, body regulation, and survival. Dysfunction of interoception is increasingly recognized as an important component of different mental health conditions including anxiety disorders, mood disorders, eating disorders, addictive disorders, somatic symptom disorders, and others. However, a number of conceptual and methodological challenges have made it difficult for interoceptive constructs to be broadly applied in mental health research and treatment settings. In November 2016, the Laureate Institute for Brain Research organized the first Interoception Summit, a gathering of interoception experts from around the world, with the goal of accelerating progress in understanding the role of interoception in mental health. The discussions at the meeting were organized around four themes: interoceptive assessment, interoceptive integration, interoceptive psychopathology, and the generation of a roadmap that could serve as a guide for future endeavors. This article presents an overview of the emerging consensus generated by the meeting.
Accessibility: Document exists in file
Language:
eng
Author:
Khalsa, S. S.
Secondary author(s):
Adolph, R., Cameron, O. G., Critchley, H. D., Davenport, P. W., Feinstein, J., Feusner, J. D., Garfinkel, S. N., Lane, R. D., Mehling, W. E., Meuret, A. E., Nemeroff, C. B., Oppenheimer, S., Petzschner, F. H., Pollatos, O., Rhudy, J. L., Schramm, L. P, Simmons, W. K., Stein, M. B., Stephan, K. E., Van Den Bergh, O., Van Diest, I., von Leupoldt, A., Paulus, M. P., the Interoception
Document type:
Article
Number of reproductions:
1
Reference:
Khalsa S.S., Adolphs R., Cameron O.G., Critchley H.D., Davenport P.W., .... the Interoception Summit 2016 participants (2018). Interoception and mental health: A roadmap. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 3(6), 501-513. https://doi.org/10.1016/j.bpsc.2017.12.004
2-year Impact Factor: 5.335|2019
Impact factor notes: Impact factor computed since 2019
Times cited: 652|2025-09-16
Indexed document: Yes
Quartile: Q1
Keywords: Interoception / Mental health / Biomarker / Research Domain Criteria (RDoC) / Computational psychiatry / Treatment

Interoception and mental health: A roadmap

Interoception and mental health: A roadmap
DocumentRobust EEG-based cross-site and cross-protocol classification of states of consciousness2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-34
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Robust EEG-based cross-site and cross-protocol classification of states of consciousness
Publication year: 2018
URL:
https://academic.oup.com/brain/article-abstract/141/11/3179/5114404?redirectedFrom=fulltext
Abstract/Results: ABSTRACT
Determining the state of consciousness in patients with disorders of consciousness is a challenging practical and theoretical problem. Recent findings suggest that multiple markers of brain activity extracted from the EEG may index the state of consciousness in the human brain. Furthermore, machine learning has been found to optimize their capacity to discriminate different states of consciousness in clinical practice. However, it is unknown how dependable these EEG markers are in the face of signal variability because of different EEG configurations, EEG protocols and subpopulations from different centres encountered in practice. In this study we analysed 327 recordings of patients with disorders of consciousness (148 unresponsive wakefulness syndrome and 179 minimally conscious state) and 66 healthy controls obtained in two independent research centres (Paris Pitié-Salpêtrière and Liège). We first show that a non-parametric classifier based on ensembles of decision trees provides robust out-of-sample performance on unseen data with a predictive area under the curve (AUC) of ~0.77 that was only marginally affected when using alternative EEG configurations (different numbers and positions of sensors, numbers of epochs, average AUC = 0.750 ± 0.014). In a second step, we observed that classifiers based on multiple as well as single EEG features generalize to recordings obtained from different patient cohorts, EEG protocols and different centres. However, the multivariate model always performed best with a predictive AUC of 0.73 for generalization from Paris 1 to Paris 2 datasets, and an AUC of 0.78 from Paris to Liège datasets. Using simulations, we subsequently demonstrate that multivariate pattern classification has a decisive performance advantage over univariate classification as the stability of EEG features decreases, as different EEG configurations are used for feature-extraction or as noise is added. Moreover, we show that the generalization performance from Paris to Liège remains stable even if up to 20% of the diagnostic labels are randomly flipped. Finally, consistent with recent literature, analysis of the learned decision rules of our classifier suggested that markers related to dynamic fluctuations in theta and alpha frequency bands carried independent information and were most influential. Our findings demonstrate that EEG markers of consciousness can be reliably, economically and automatically identified with machine learning in various clinical and acquisition contexts.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Engemann, D. A.
Secondary author(s):
Raimondo, F., King, J. R., Rohaut, B., Louppe, G., Faugeras, F., Annen, J., Cassol, H., Gosseries, O., Fernandez-Slezak, D., Laureys, S., Naccache, L., Dehaene, S., Sitt, J. D.
Document type:
Article
Number of reproductions:
3
Reference:
Engemann, D. A., Raimondo, F., King, J. R., Rohaut, B., Louppe, G., Faugeras, F., ... Sitt, J. D. (2018). Robust EEG-based cross-site and cross-protocol classification of states of consciousness. Brain, 141(11), 3179-3192. https://doi.org/10.1093/brain/awy251
2-year Impact Factor: 11.814|2018
Times cited: 195|2025-09-17
Indexed document: Yes
Quartile: Q1
Keywords: Electroencephalography / Disorders of consciousness / Biomarker / Machine learning / Diagnosis
DocumentComparing SPM12 and CAT12 segmentation pipelines: a brain tissue volume-based age and Alzheimer's disease study2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-292
Location: BF-GMS
Title:
292 - Oxytocin: On the psychophysiology of trust and cooperation
Duration: 2017-10 - 2023-11
Researcher(s):
Diana Prata, James Rilling, Manuel Lopes, Duarte Ferreira, Daniel Martins, Pedro Levy
Institution(s): FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências (Portugal); Emory University, Atlanta (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Prata, D.
Secondary author(s):
Rilling, J., Lopes, M., Ferreira, D. , Martins, D., Levy, P.
Number of reproductions:
1
Keywords:
Oxytocin / Mentalizing / Theory of mind / Dopamine / Psychophysiology

Reference code: PT/FB/BL-2016-292.02
Location: BF-GMS
Title:
Comparing SPM12 and CAT12 segmentation pipelines: a brain tissue volume-based age and Alzheimer's disease study
Publication year: 2020
URL:
https://www.sciencedirect.com/science/article/pii/S0165027019304224?via%3Dihub
Abstract/Results: ABSTRACT:
BACKGROUND:
Brain volumes have been used as research biomarkers both in health and in Alzheimer's disease(AD). In order to improve the comparability between studies and aid future analytical software platform choice in the research setting, here we compare two segmentation pipelines of structural brain magnetic resonance imaging(sMRI): the SPM12 toolbox, and a SPM12 add-on, the CAT12 toolbox.
METHODS:
We segmented 1.5T and 3T T1-weighted sMRI images (from the OASIS-brain database) using both pipelines and compared them in terms of their impact on: 1)the effect of age on the total grey matter(GM) and white matter(WM), and on the hippocampi GM volumes in a healthy sample(n?=?238); 2)the effect of AD diagnosis on the same volume measures; and 3)the accuracy of each volume measure detecting diagnosis (100 patients with AD and 78 age- and gender-matched healthy subjects).
RESULTS AND COMPARISON BETWEEN METHODS:
Our results demonstrated that: 1)volume estimates from SPM12 were highly correlated with the ones from CAT12, albeit absolute differences between pipelines were tissue specific; 2)the choice of pipeline modulated the effect of age on all volume measures and of diagnosis on hippocampi GM volumes computed from 3?T data; and 3)pipeline had no impact on the accuracy of any brain volume measure detecting AD diagnosis.
CONCLUSIONS:
Our findings indicate that other studies should take these pipeline effects on age and AD diagnosis, into account, for improved comparability in previous literature. Additionally, we encourage future studies to use CAT12 as this is a more advanced and computationally efficient brain segmentation tool.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Tavares, V.
Secondary author(s):
Prata, D., Ferreira, H. A.
Document type:
Article
Number of reproductions:
1
Reference:
Tavares, V., Prata, D., & Ferreira, H. A. (2020). Comparing SPM12 and CAT12 segmentation pipelines: a brain tissue volume-based age and Alzheimer's disease study. Journal of Neuroscience Methods, 334: 108565. https://doi.org/10.1016/j.jneumeth.2019.108565
2-year Impact Factor: 2.390|2020
Times cited: 39|2025-09-18
Indexed document: Yes
Quartile: Q3
Keywords: Brain tissue segmentation / SPM12 / CAT12 / Alzheimer’s disease diagnosis / Biomarker / Aging
DocumentCan the Neural Representation of Physical Pain Predict Empathy for Pain in Others?2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-125
Location: BF-GMS
Title:
125 - Distinct psychophysiological profiles associated with experiencing the pain of others
Duration: 2019-03 - 2024-03
Researcher(s):
Jamie Ward, Mengze Li
Institution(s): School of Psychology, University of Sussex (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progrees report
Final report
Articles
Language: eng
Author:
Ward, J.
Secondary author(s):
Li, M.
Number of reproductions:
1
Keywords:
Vicarious pain / Consciousness / Interoception / Unusual experiences / Psychophysiology

Reference code: PT/FB/BL-2018-125.02
Location: BF-GMS
Title:
Can the Neural Representation of Physical Pain Predict Empathy for Pain in Others?
Publication year: 2024
URL:
https://academic.oup.com/scan/advance-article/doi/10.1093/scan/nsae023/7628337
Abstract/Results: ABSTRACT:
The question of whether physical pain and vicarious pain have some shared neural substrates is unresolved. Recent research has argued that physical and vicarious pain are represented by dissociable multivariate brain patterns by creating biomarkers for physical pain (Neurologic Pain Signature, NPS) and vicarious pain (Vicarious Pain Signature, VPS) respectively. In the current research, the NPS and two versions of the VPS were applied to three fMRI datasets (one new, two published) relating to vicarious pain which focused on between-subject differences in vicarious pain (Datasets 1 and 3) and within-subject manipulations of perspective taking (Dataset 2). Results show that (1) NPS can distinguish brain responses to images of pain versus no-pain and to a greater extent in vicarious pain responders who report experiencing pain when observing pain, (2) neither version of the VPS mapped on to individual differences in vicarious pain and the two versions differed in their success in predicting vicarious pain overall. This study suggests that the NPS (created to detect physical pain) is, under some circumstances, sensitive to vicarious pain and there is significant variability in VPS measures (created to detect vicarious pain) to act as generalizable biomarkers of vicarious pain.
Accessibility: Document exists in file
Language:
eng
Author:
Li, M.
Secondary author(s):
Racey, C., Rae, C. L., Strawson, W., Critchley, H. D., Ward, J.
Document type:
Article
Number of reproductions:
1
Reference:
Li, M., Racey, C., Rae, C. L., Strawson, W., Critchley, H. D., & Ward, J. (2024). Can the Neural Representation of Physical Pain Predict Empathy for Pain in Others? Social Cognitive and Affective Neuroscience, 19(1), nsae023. https://doi.org/10.1093/scan/nsae023
2-year Impact Factor: 3.1|2024
Times cited: 4|2025-09-26
Indexed document: Yes
Quartile: Q1
Keywords: Pain / Empathy / Biomarker / fMRI / Individual differences

Can the Neural Representation of Physical Pain Predict Empathy for Pain in Others?

Can the Neural Representation of Physical Pain Predict Empathy for Pain in Others?