Reference code: | PT/FB/BL-2008-146.11 |
Location: | Arquivo PCA - Pasta 13/2008
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Title:
| Clinical correlates of cortical auditory evoked potentials in preterm newborns
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Publication year: | 2011
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URL:
| http://www.researchgate.net/publication/236851474_Poster_sessions_S131-132_P25.5_Clinical_correlates_of_cortical_auditory_evoked_potentials_in_preterm_newborns
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Abstract/Results: | ABSTRACT:
Background - Cortical auditory evoked potentials (CAEPs) may serve as an early index of developmental problems in the
auditory cortex.
Aim - To determine the effects of neonatal risk factors on maturational changes of CAEPs components.
Methods: Auditory processing was investigated before discharge in forty-two NICU admitted premature infants (mean
gestational age-GA 30 weeks, range 23-34). Recordings consisted of the average of 150 responses to 1000 Hz pure tones (inter-stimulus interval 1250 1850 ms) recorded at frontocentral locations. CAEP components were correlated with GA, gender, bronco-pulmonary dysplasia (BPD), retinopathy of prematurity (ROP), intra-ventricular haemorrhage (IVH),
intrauterine growth restriction (IUGR), resuscitation at birth, patent ductus arteriosus (PDA), infections, use of antenatal
steroids.
Results - CAEP components were significantly correlated with GA (p = 0.001), BPD (p = .002), ROP (p = .02), IVH (p = .019)
and resuscitation (p = .045); moreover ROP and BPD were significantly higher in infants born at GA< 29 weeks and the
occurrence of ROP or BPD was the only significant finding in a multivariate analysis.
Conclusions - Cortical auditory processing appears to be influenced by neonatal clinical data associated with fetal
inflammatory response, complicating extremely preterm birth. These findings points to the importance of early risk factors on brain development.
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Accessibility: | Document exists in file
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Copyright/Reproduction:
| By permission
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Language:
| eng
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Author:
| Suppiej, A.
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Secondary author(s):
| Cainelli, E., Cappellari, A., Scarabel, E., Zanardo, V., Bisiacchi, P.
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Document type:
| Conference abstract
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Number of reproductions:
| 1
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Reference:
| Suppiej, A., Cainelli, E., Cappellari, A., Scarabel, E., Zanardo, V., & Bisiacchi, P. (2011). In Proceeding of the 9th Congress of the European Paediatric Neurology Society EPNS (S132-S134). Cavtat-Dubrovnik, Croatia.
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Indexed document: | No
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Keywords: | Preterm infants / Auditory system / Brain development
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