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DocumentPhysiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis2005

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1998
Location: Arquivo PCA - Pastas 1 a 11/1998
Title:
1998 Grants
Start date: 1999-01 - 2005-12
Dimension/support:
11 caixas de arquivo

Reference code: PT/FB/BL-1998-030
Location: Arquivo PCA - Pasta 9/1998
Title:
030 - Caracterização neurofisiológica e psicofisiológica de disfunções cerebrais utilizando estudos qEEG/ERP. Metodologia e aplicações
Duration: 1999-06 - 2004-04
Researcher(s):
António Martins da Silva, Denisa Maria Vasques Mendonça, João Manuel Carmona Ferreira Lopes, Maria Regina Pinto Brito Aguiar Andrade, João Eduardo Paiva Ramalheira, João Paulo Trigueiros Silva Cunha, Miguel Oliveira e Silva, Teresa Temudo, Óscar Gomes, Óscar Alves
Institution(s): Hospital Sto. António, Porto (Portugal)
Language: por
Author:
Martins da Silva, A.
Secondary author(s):
Mendonça, D., Lopes, J., Andrade, M., Ramalheira, J., Cunha, J., Silva, M. O., Temudo, T., Gomes, Ó., Alves, Ó.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Brain dysfunction

Reference code: PT/FB/BL-1998-030.02
Location: Arquivo PCA - Pasta 9/1998
Title:
Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis
Publication year: 2005
URL:
http://www.neurologia.es/sec/deAutor.php?auof=586&i=e#
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=125&SID=V1leIhH4ysTdNpr3OrX&page=1&doc=1
Accessibility: Document exists in file (Portuguese version)
Copyright/Reproduction:
By permission
Language:
spa
Author:
Vilhena, E.
Secondary author(s):
Paiva, I., Rodrigues, H., Martins da Silva, A., Mendonça, D.
Document type:
Article
Number of reproductions:
1
Reference:
Vilhena, E., Paiva, I., Rodrigues, H., Martins da Silva, A., & Mendonça, D. (2005). Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis. Revista de Neurologia, 41(10), 633-635.
2-year Impact Factor: 0.391|2005
Times cited: 0|2025-02-04
Indexed document: Yes
Quartile: Q4
Keywords: P300 / Brain function / Amplitude / Latency / Cognitive potentials / Evoked potentials / Analysis of variance with repeated measures

Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis

Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis
DocumentBrain coordination dynamics of the processing of self-referential stimuli2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-033
Location: Arquivo PCA - Pasta 15/2004
Title:
033 - Dynamic brain patterns in neocortical areas during interpersonal transactions
Duration: 2005-01 - 2008-07
Researcher(s):
Richard Wennberg, Jose Luis Perez Velazquez
Institution(s): Krembil Neuroscience Centre, Toronto Western Hospital and The Hospital for Sick Children, University of Toronto (Canada)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Wennberg, R.
Secondary author(s):
Perez Velazquez, J. L.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Pain / Emotion / Empathy

Reference code: PT/FB/BL-2004-033.03
Location: Arquivo PCA - Pasta 15/2004
Title:
Brain coordination dynamics of the processing of self-referential stimuli
Publication year: 2006
Accessibility:
Document does not exist in file
Language:
eng
Author:
Garcia Dominguez, L.
Secondary author(s):
Gaetz, W., Cheyne, D., Wennberg, R., Perez Velazquez, J. L.
Document type:
Abstract
Number of reproductions:
1
Reference:
Garcia Dominguez, L., Gaetz, W., Cheyne, D., Wennberg, R., & Perez Velazquez, J. L. (2006). Brain coordination dynamics of the processing of self-referential stimuli. NeuroImage, 31(Suppl 1), S119.
Indexed document: Yes
Keywords: Psychophysiology / Brain function
DocumentFinal report - Event-related potentials of temperament traits in ADHD and conduct disorder2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-119
Location: Arquivo PCA - Pasta 15/2004
Title:
119 - Event-related potentials of temperament traits in ADHD and conduct disorder
Duration: 2005-06 - 2007-11
Researcher(s):
Katya Rubia, Alexander Sumich, Philip Asherson, Eric Taylor
Institution(s): Dept. Child Adolescent Psychiatry,Institute of Psychiatry, London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Rubia, K.
Secondary author(s):
Sumich, A., Asherson, P., Taylor, E.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Childhood and adolescent disorders / Conduct disorder / Attention deficit hyperactivity disorder (ADHD) / Developmental psychology

Reference code: PT/FB/BL-2004-119.01
Location: Arquivo PCA - Pasta 15/2004
Title:
Final report - Event-related potentials of temperament traits in ADHD and conduct disorder
Publication year: 2007
URL:
http://www.bial.com/imagem/Bolsa11904_21022014.pdf
Abstract/Results: RESULTS:
The aim of this study was to understand brain function involved in symptoms and temperament traits of ADHD and conduct disorder. The project includes 80 adolescent boys into the study (30 healthy individuals, 30 boys with ADHD, 20 boys with conduct disorder). We also made use of an international database of 245 children and adolescents to investigate maturational changes in brain function.
A structured clinical interview was used to diagnose developmental problems including Attention Deficit and Hyperactivity Disorder (ADHD), oppositional defiant disorder (ODD) and Conduct Disorder (CD). A number of techniques were used to measure brain function including electroencephalography, event-related potentials and neuropsychology measures. Brain function assessment was performed using brain resource company techniques (www.brainresource.com). We also used several self and parent report instruments to measures symptoms and temperament traits, in particular we were interested in callous/unemotional traits, emotional intelligence, affective problems, pragmatic language impairment, hyperactivity, impulsivity, and aggression. Data from this project have been presented in poster and oral form at the Applied Neuroscience Conference, May 17-20, 2007. Two manuscripts have been submitted, to Developmental Neuropsychology and to The Journal of Child Psychology and Psychiatry. The first of these studies investigates sex differences in the ontogenetic development of N200 and P300 components of the event-related potential. The second observes
neurodevelopmental differences between healthy and behaviourally problematic adolescents, and investigates the relationship of involved mechanisms to clinical scores. Further publications from this dataset are in preparation.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Notes:
Annexes contain abstracts of five masters thesis
Author: Rubia, K.
Secondary author(s):
Sumich, A.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Brain function / Attention deficit hyperactivity disorder (ADHD) / Conduct disorder

Final report - Event-related potentials of temperament traits in ADHD and conduct disorder

Final report - Event-related potentials of temperament traits in ADHD and conduct disorder
DocumentFinal report - Attentional modulation in neural responses to faces2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-063
Location: Arquivo PCA - Pasta 22/2004
Title:
063 - Attentional modulation in neural responses to faces
Duration: 2005-02 - 2009-07
Researcher(s):
Jaime Iglesias Dorado
Institution(s): Universidad Autónoma de Madrid, Facultad de Psicologia (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
7 articles (5 published and 2 submitted)
Previous versions of papers submitted for publication, which were afterwards published
Language: spa / eng
Author:
Dorado, J. I.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Attention / Perception / Emotion / Brain structure and function

Reference code: PT/FB/BL-2004-063.01
Location: Arquivo PCA - Pasta 22/2004
Title:
Final report - Attentional modulation in neural responses to faces
Publication year: 2009
URL:
https://www.bial.com/imagem/Bolsa6304.pdf
Abstract/Results: RESULTS:
Event-related potentials analysed in consecutive studies led us to the following findings: a) the perception of fear from faces is gated by selective attention at early latencies, whereas only after 480 ms was the perception of disgust modulated by attention allocation; b) the order of presentation of external and internal facial features influence the integration of facial components into face gestalts, so that the external features may be especially relevant for initial object categorization while internal features would be more closely related to subsequent configural mechanisms; c) the verbal N400 wave was distinguished from its functional analogue during the processing of faces in a contextual preactivation task, which showed a predominantly occipital localization and differentiated neural generators; d) N400-like components elicited in a face-feature matching task revealed a larger and longer-lasting N400 effect with the prior presentation of internal features around 300-400 ms post-stimulus, involving a greater activation of frontal and left temporal brain areas; e) both explicit and implicit processing of famous faces resulted in an enhanced N250 whereas explicit processing was specifically associated with earlier N400 and P600, related to an increased activity within brain areas involved in identity processing around 250 and 450 ms; and f) the processing of familiar vs. unfamiliar faces in the face-feature matching task revealed that the so-called “internal features advantage” relies on the use of stored face-identity-related information around 300-600 ms, involving an incremented activity elicited by familiar stimuli in both posterior (ventral occipitotemporal) and more anterior (parahippocampal and orbitofrontal) brain regions.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Notes:
The final report contains in attachment articles published and/or submitted for publication
Author: Iglesias, J.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Perception / Attention / Emotion / Brain function
DocumentFinal report - Pronouns and degeneration: Differences in processes and brain locations involved in pronoun interpretation in prodromal Alzheimer's disease and in healthy ageing2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-035
Location: Arquivo PCA - Pasta 24/2004
Title:
035 - Pronouns and degeneration: Differences in processes and brain locations involved in pronoun interpretation in prodromal Alzheimer's disease and in healthy ageing
Duration: 2005-10 - 2010-09
Researcher(s):
José Augusto da Veiga Pinto de Gouveia, António Manuel Horta Branco, Horácio António de Jesus Firmino, José Augusto Simões Gonçalves Leitão, Maria Isabel Ferraz Festas
Institution(s): Núcleo de Estudos e Intervenção Cognitivo-Comportamental, Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: por
Author:
Gouveia, J. P.
Secondary author(s):
Branco, A., Firmino, H., Leitão, J., Festas, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Cognitive processes / Language / Biopsychological problems / Neurodegenerative disorders / Mild cognitive impairment (MCI) / Brain structure and function / Alzheimer's disease

Reference code: PT/FB/BL-2004-035.01
Location: Arquivo PCA - Pasta 24/2004
Title:
Final report - Pronouns and degeneration: Differences in processes and brain locations involved in pronoun interpretation in prodromal Alzheimer's disease and in healthy ageing
Publication year: 2010
URL:
http://www.bial.com/imagem/Bolsa35-04_03012014.pdf
Abstract/Results: RESULTS:
We used event related potentials (ERPs) and sLORETA to determine how the management of processing cost in pronoun interpretation is affected by age (young vs. elderly) and by the presence of a cue for pragmatic inferencing. The syntactic relation between an explicit pronoun and its antecedent was manipulated, yielding two types of sentences (Type 1: syntactic (cheap) or discourse (costly) processing routes available; violation of a conversational convention vs. Type 2: exclusive availability of the discourse route; conformity to conversational conventions). For the young adults a Late Positivity and selective activation of right BA9 and BA31 emerged in type 1 sentences, indexing the effort required to compute the pragmatic inference cued by the violation of a conversational convention (use of an explicit pronoun in type 1 sentences, where a null/silent would be more likely). This effect is absent in older participants, suggesting that, in their case, the processor fails to initially capture the oddity of the explicit pronoun, which is therefore conveniently processed at the cheaper syntactic level, but rendering the identity of its original form unavailable for later pragmatic inferential processing. Thus, older participants, unlike the young, recruit different processing routes for each sentence type, as demonstrated by an N400 and selective activation of right BA18 for type 2 sentences, in which only the discourse route is available. This N400 is absent in younger participants, since the clash between the expected null pronoun and the explicit one occurring in type 1 sentences leads the processor to shift resolution to the discourse level, where the unexpected form will remain accessible to the pragmatic module.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
por
Author:
Gouveia, J. P.
Secondary author(s):
Branco, A., Firmino, H., Leitão, J., Festas, M.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Alzheimer's disease / Aging / Language / Mild cognitive impairment (MCI) / Brain function

Final report - Pronouns and degeneration: Differences in processes and brain locations involved in pronoun interpretation in prodromal alzheimer's disease and in healthy ageing

Final report - Pronouns and degeneration: Differences in processes and brain locations involved in pronoun interpretation in prodromal alzheimer's disease and in healthy ageing
DocumentSex Differences in Brain Maturation as Measured Using Event-Related Potentials2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-119
Location: Arquivo PCA - Pasta 15/2004
Title:
119 - Event-related potentials of temperament traits in ADHD and conduct disorder
Duration: 2005-06 - 2007-11
Researcher(s):
Katya Rubia, Alexander Sumich, Philip Asherson, Eric Taylor
Institution(s): Dept. Child Adolescent Psychiatry,Institute of Psychiatry, London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Rubia, K.
Secondary author(s):
Sumich, A., Asherson, P., Taylor, E.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Childhood and adolescent disorders / Conduct disorder / Attention deficit hyperactivity disorder (ADHD) / Developmental psychology

Reference code: PT/FB/BL-2004-119.04
Location: Arquivo PCA - Pasta 15/2004
Title:
Sex Differences in Brain Maturation as Measured Using Event-Related Potentials
Publication year: 2012
URL:
http://www.tandfonline.com/doi/full/10.1080/87565641.2011.653461#.Umj5tl9dYdU
Abstract/Results: ABSTRACT:
Little is known about how sex influences functional brain maturation. The current study investigated sex differences in the maturation of event-related potential (ERP) amplitudes during an auditory oddball task (N = 170; age = 6–17 years). Performance improved with age. N200 amplitude declined with age: parietal sites showed earlier development than temporal and frontal locations. Girls showed greater bilateral frontal P300 amplitude development, approaching the higher values observed in boys during childhood. After controlling for age, right frontal P300 amplitude was associated with reaction time in girls. The findings demonstrate sex differences in ERP maturation in line with behavioral and neuroimaging studies.
Accessibility: Document does not exist in file
Language:
eng
Author:
Sumich, A.
Secondary author(s):
Sarkar, S., Hermens, D., Ibrahimovic, A., Taylor, A., Rubia, K.
Document type:
Article
Number of reproductions:
1
Reference:
Sumich, A., Sarkar, S., Hermens, D., Ibrahimovic, A., Taylor, A., & Rubia, K. (2012). Sex differences in brain maturation as measured using event-related potentials. Developmental Neuropsychology, 37(5), 415-433. https://doi.org/10.1080/87565641.2011.653461
2-year Impact Factor: 2.899|2012
Times cited: 21|2025-02-10
Indexed document: Yes
Quartile: Q2
Keywords: Sex effects / Brain function / Maturation / Neuroimaging studies / Event-related potential (ERP)
DocumentO cérebro analfabeto: A influência do conhecimento das regras da leitura e da escrita na função cerebral

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/043
Title: O cérebro analfabeto: A influência do conhecimento das regras da leitura e da escrita na função cerebral
Número de inventário: M-0044
Local: Porto
Publisher: Laboratórios Bial
Date: 2002
Pag., vols.: 198 p.
Illustration: il., graphs
Dimension/support: 24 cm
Accessibility: Document exists in archive
Copyright/Reproduction:
By permission
Language:
por
Notes:
Grande Prémio Bial de Medicina 2002
Edition: 1ª ed.
Collection: ( ; 28)
Author: Castro-Caldas, A.
Document type:
Book
Keywords:
Brain function / Brain activity / Language / Reading / Writing / Neuropsychology
DocumentEstimulação cerebral profunda: Do tratamento da doença de Parkinson a uma nova visão do funcionamento do cérebro

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/056
Title: Estimulação cerebral profunda: Do tratamento da doença de Parkinson a uma nova visão do funcionamento do cérebro
Número de inventário: M-0057
Local: Porto
Publisher: Laboratórios Bial
Date: 2011
Pag., vols.: 350 p.
Illustration: il., graphs
Dimension/support: 24 cm
Accessibility: Document exists in archive
Copyright/Reproduction:
By permission
Language:
por
Notes:
Prémio Bial 2010 - Menção Honrosa
Edition: 1ª ed.
Collection: (Bial ; 42)
Author: Vaz, R.
Secondary author(s):
Garrett, C., Massano, J., Rosas, M., Abreu, P., Fonseca, R., Sousa, C., Norton, A., Basto, M. A., Reis, C., Gago, M., Linhares, P., Rebelo, V., Vale, P., Oliveira, J. P., Ribeiro, I., Toste, T., Moreira, R., Chamadoira, C.
Document type:
Book
Keywords:
Parkinson's disease / Brain function / Deep brain stimulation / Neurosurgery
DocumentGeneral anesthesia: A probe to explore consciousness2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-43
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
General anesthesia: A probe to explore consciousness
Publication year: 2019
URL:
https://www.frontiersin.org/articles/10.3389/fnsys.2019.00036/full
Abstract/Results: ABSTRACT:
General anesthesia reversibly alters consciousness, without shutting down the brain globally. Depending on the anesthetic agent and dose, it may produce different consciousness states including a complete absence of subjective experience (unconsciousness), a conscious experience without perception of the environment (disconnected consciousness, like during dreaming), or episodes of oriented consciousness with awareness of the environment (connected consciousness). Each consciousness state may potentially be followed by explicit or implicit memories after the procedure. In this respect, anesthesia can be considered as a proxy to explore consciousness. During the recent years, progress in the exploration of brain function has allowed a better understanding of the neural correlates of consciousness, and of their alterations during anesthesia. Several changes in functional and effective between-region brain connectivity, consciousness network topology, and spatio-temporal dynamics of between-region interactions have been evidenced during anesthesia. Despite a set of effects that are common to many anesthetic agents, it is still uneasy to draw a comprehensive picture of the precise cascades during general anesthesia. Several questions remain unsolved, including the exact identification of the neural substrate of consciousness and its components, the detection of specific consciousness states in unresponsive patients and their associated memory processes, the processing of sensory information during anesthesia, the pharmacodynamic interactions between anesthetic agents, the direction-dependent hysteresis phenomenon during the transitions between consciousness states, the mechanisms of cognitive alterations that follow an anesthetic procedure, the identification of an eventual unitary mechanism of anesthesia-induced alteration of consciousness, the relationship between network effects and the biochemical or sleep-wake cycle targets of anesthetic agents, as well as the vast between-studies variations in dose and administration mode, leading to difficulties in between-studies comparisons. In this narrative review, we draw the picture of the current state of knowledge in anesthesia-induced unconsciousness, from insights gathered on propofol, halogenated vapors, ketamine, dexmedetomidine, benzodiazepines and xenon. We also describe how anesthesia can help understanding consciousness, we develop the above-mentioned unresolved questions, and propose tracks for future research.
Accessibility: Document exists in file
Language:
eng
Author:
Bonhomme, V.
Secondary author(s):
Staquet, C., Montupil, J., Defresne, A., Kirsch, M., Martial, C., Vanhaudenhuyse, A., Chatelle, C., Larroque, S. K., Raimondo, F., Demertzi, A., Bodart, O., Laureys, S., Gosseries, O.
Document type:
Article
Number of reproductions:
3
Reference:
Bonhomme, V., Staquet, C., Montupil, J., Defresne, A., Kirsch, M., Martial, C., ..., Gosseries, O. (2019). General anesthesia: A probe to explore consciousness. Frontiers in Systems Neuroscience, 13, 1662-5137. https://doi.org/10.3389/fnsys.2019.00036
2-year Impact Factor: 3.293|2019
Times cited: 58|2025-02-13
Indexed document: Yes
Quartile: Q2
Keywords: General anesthesia / Consciousness / Mechanisms / Brain function / Brain networks

General anesthesia: A probe to explore consciousness

General anesthesia: A probe to explore consciousness
DocumentThe nature of consciousness in anaesthesia2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-129
Location: BF-GMS
Title:
The nature of consciousness in anaesthesia
Publication year: 2023
URL:
https://doi.org/10.1016/j.bjao.2023.100224
Abstract/Results: ABSTRACT:
Neuroscientists agree on the value of locating the source of consciousness within the brain. Anaesthesiologists are no exception, and have their own operational definition of consciousness based on phenomenological observations during anaesthesia. The full functional correlates of consciousness are yet to be precisely identified, however rapidly evolving progress in this scientific domain has yielded several theories that attempt to model the generation of consciousness. They have received variable support from experimental observations, including those involving anaesthesia and its ability to reversibly modulate different aspects of consciousness. Aside from the interest in a better understanding of the mechanisms of consciousness, exploring the functional tenets of the phenomenological consciousness states of general anaesthesia has the potential to ultimately improve patient management. It could facilitate the design of specific monitoring devices and approaches, aiming at reliably detecting each of the possible states of consciousness during an anaesthetic procedure, including total absence of mental content (unconsciousness), and internal awareness (sensation of self and internal thoughts) with or without conscious perception of the environment (connected or disconnected consciousness, respectively). Indeed, it must be noted that unresponsiveness is not sufficient to infer absence of connectedness or even absence of consciousness. This narrative review presents the current knowledge in this field from a system-level, underlining the contribution of anaesthesia studies in supporting theories of consciousness, and proposing directions for future research.
Accessibility: Document exists in file
Language:
eng
Author:
Montupil, J.
Secondary author(s):
Cardone, P., Staquet, C., Bonhomme, A., Defresne, A., Martial, C., Alnagger, N. L. N., Gosseries, O., Bonhomme, V.
Document type:
Article
Number of reproductions:
3
Reference:
Montupil, J., Cardone, P., Staquet, C., Bonhomme, A., Defresne, A., Martial, C., Alnagger, N. L. N., Gosseries, O., & Bonhomme, V. (2023). The nature of consciousness in anaesthesia. BJA Open, 8, 100224. https://doi.org/10.1016/j.bjao.2023.100224
2-year Impact Factor: N/A
Times cited: N/A
Indexed document: Yes
Quartile: N/A
Keywords: Brain function / Consciousness / General anaesthesia / Mechanisms / Theories

The nature of consciousness in anaesthesia

The nature of consciousness in anaesthesia
DocumentRe-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-135
Location: BF-GMS
Title:
Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation
Publication year: 2024
URL:
https://doi.org/10.1371/journal.pcbi.1011350
Abstract/Results: ABSTRACT:
A fundamental challenge in neuroscience is accurately defining brain states and predicting how and where to perturb the brain to force a transition. Here, we investigated resting-state fMRI data of patients suffering from disorders of consciousness (DoC) after coma (minimally conscious and unresponsive wakefulness states) and healthy controls. We applied model-free and model-based approaches to help elucidate the underlying brain mechanisms of patients with DoC. The model-free approach allowed us to characterize brain states in DoC and healthy controls as a probabilistic metastable substate (PMS) space. The PMS of each group was defined by a repertoire of unique patterns (i.e., metastable substates) with different probabilities of occurrence. In the model-based approach, we adjusted the PMS of each DoC group to a causal whole-brain model. This allowed us to explore optimal strategies for promoting transitions by applying off-line in silico probing. Furthermore, this approach enabled us to evaluate the impact of local perturbations in terms of their global effects and sensitivity to stimulation, which is a model-based biomarker providing a deeper understanding of the mechanisms underlying DoC. Our results show that transitions were obtained in a synchronous protocol, in which the somatomotor network, thalamus, precuneus and insula were the most sensitive areas to perturbation. This motivates further work to continue understanding brain function and treatments of disorders of consciousness.
Accessibility: Document exists in file
Language:
eng
Author:
Dagnino, P. C.
Secondary author(s):
Escrichs, A., López-González, A., Gosseries, O., Annen, J., Sanz Perl, Y., Kringelbach, M. L., Laureys, S., Deco, G.
Document type:
Article
Number of reproductions:
3
Reference:
Dagnino, P. C., Escrichs, A., López-González, A., Gosseries, O., Annen, J., Sanz Perl, Y., Kringelbach, M. L., Laureys, S., & Deco, G. (2024). Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation. PLOS Computational Biology, 20(5), e1011350. https://doi.org/10.1371/journal.pcbi.1011350
2-year Impact Factor: 3.8|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 1|2025-02-19
Indexed document: Yes
Quartile: Q1
Keywords: Disorders of consciousness (DoC) / Coma / Probabilistic metastable substate (PMS) / Brain function

Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation

Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation