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BIAL Foundation
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DE:"Brain functional architecture"
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DocumentBrain network profiling defines functionally specialized cortical networks2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-195
Location: BF-GMS
Title:
195 - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
Duration: 2017-04 - 2019-10
Researcher(s):
Sjoerd Ebisch, Mauro Gianni Perrucci
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Ebisch, S.
Secondary author(s):
Perrucci, M. G.
Number of reproductions:
1
Keywords:
Intrinsic self / Extrinsic self / Brain network interactions / Neuroimaging / Psychophysiology

Reference code: PT/FB/BL-2016-195.02
Location: BF-GMS
Title:
Brain network profiling defines functionally specialized cortical networks
Publication year: 2018
URL:
https://onlinelibrary.wiley.com/doi/abs/10.1002/hbm.24315
Abstract/Results: ABSTRACT:
Neuroimaging research made rapid advances in the study of the functional architecture of the brain during the past decade. Many proposals endorsed the relevance of large-scale brain networks, defined as ensembles of brain regions that exhibit highly correlated signal fluctuations. However, analysis methods need further elaboration to define the functional and anatomical extent of specialized subsystems within classical networks with a high reliability. We present a novel approach to characterize and examine the functional proprieties of brain networks. This approach, labeled as brain network profiling (BNP), considers similarities in task-evoked activity and resting-state functional connectivity across biologically relevant brain subregions. To combine task-driven activity and functional connectivity features, principal components were extracted separately for task-related beta values and resting-state functional connectivity z-values (data available from the Human Connectome Project), from 360 brain parcels. Multiple clustering procedures were employed to assess if different clustering methods (Gaussian mixtures; k-means) and/or data structures (task and rest data; only rest data) led to improvements in the replication of the brain architecture. The results indicated that combining information from resting-state functional connectivity and task-evoked activity and using Gaussian mixtures models for clustering produces more reliable results (99% replication across data sets). Moreover, the findings revealed a high-resolution partition of the cerebral cortex in 16 networks with unique functional connectivity and/or task-evoked activity profiles. BNP potentially offers new approaches to advance the investigation of the brain functional architecture.
Accessibility: Document does not exist in file
Language:
eng
Author:
Di Plinio, S.
Secondary author(s):
Ebisch, S.
Document type:
Article
Number of reproductions:
1
Percentiles:
57.77|0.55
Reference:
Di Plinio, S., & Ebisch, S. (2018). Brain network profiling defines functionally specialized cortical networks. Human Brain Mapping, 39(12), 4689-4706. https://doi.org/10.1002/hbm.24315
2-year Impact Factor: 4.554|2018
Times cited: 15|2026-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Gaussian mixture model / Brain functional architecture / Clustering / Parallel analysis / Principal component analysis / Resting-state fMRI / task fMRI