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File074 - Optogenetic circuit dissection of neural instructive signals for cerebellum-dependent learning2015-062018-10

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-074
Location: BF-GMS
Title:
074 - Optogenetic circuit dissection of neural instructive signals for cerebellum-dependent learning
Duration: 2015-06 - 2018-10
Researcher(s):
Dominique Leon Pritchett, Catarina Albergaria, Megan R. Carey
Institution(s): Champalimaud Centre for the Unknown, Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Author: Pritchett, D.
Secondary author(s):
Albergaria, C., Carey, M. R.
Number of reproductions:
1
Keywords:
Cerebellum / Optogenetics / Classical conditioning / Instructive signals / Psychophysiology

File495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly2015-072022-03

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

DocumentEnvironmental factors linked to depression vulnerability are associated with altered cerebellar resting-state synchronisation2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-262
Location: Arquivo PCA - Pasta 29/2012
Title:
262 - The neural basis of Magical Ideation: A multimodal imaging study in twin subjects
Duration: 2013-08 - 2019-07
Researcher(s):
Paolo Brambilla, Gioia Negri, Sara Piccin, Giuseppe Cabras, Corrado Fagnani
Institution(s): Universitá delgi Studi di Milano and Unit of Epidemiology of the Italian Institute of Health, Rome (Italy)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Articles
Language: eng
Author:
Brambilla, P.
Secondary author(s):
Negri, G., Piccin, S., Cabras, G., Fagnani, C.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Paranormal belief / Brain structure and function / Personality

Reference code: PT/FB/BL-2012-262.09
Location: Arquivo PCA - Pasta 29/2012
Title:
Environmental factors linked to depression vulnerability are associated with altered cerebellar resting-state synchronisation
Publication year: 2016
URL:
http://www.nature.com/articles/srep37384
Abstract/Results: ABSTRACT:
Hosting nearly eighty percent of all human neurons, the cerebellum is functionally connected to large regions of the brain. Accumulating data suggest that some cerebellar resting-state alterations may constitute a key candidate mechanism for depressive psychopathology. While there is some evidence linking cerebellar function and depression, two topics remain largely unexplored. First, the genetic or environmental roots of this putative association have not been elicited. Secondly, while different mathematical representations of resting-state fMRI patterns can embed diverse information of relevance for health and disease, many of them have not been studied in detail regarding the cerebellum and depression. Here, high-resolution fMRI scans were examined to estimate functional connectivity patterns across twenty-six cerebellar regions in a sample of 48 identical twins (24 pairs) informative for depression liability. A network-based statistic approach was employed to analyze cerebellar functional networks built using three methods: the conventional approach of filtered BOLD fMRI time-series, and two analytic components of this oscillatory activity (amplitude envelope and instantaneous phase). The findings indicate that some environmental factors may lead to depression vulnerability through alterations of the neural oscillatory activity of the cerebellum during resting-state. These effects may be observed particularly when exploring the amplitude envelope of fMRI oscillations.
Accessibility: Document exists in file
Language:
eng
Author:
Córdova-Palomera, A.
Secondary author(s):
Tornador, C., Falcón, C., Bargalló, N., Brambilla, P., Crespo-Facorro, B., Deco, G., Fañanás, L.
Document type:
Article
Number of reproductions:
3
Reference:
Córdova-Palomera, A., Tornador, C., Falcón, C., Bargalló, N., Brambilla, P., Crespo-Facorro, B., Deco, G., & Fañanás, L. (2016). Environmental factors linked to depression vulnerability are associated with altered cerebellar resting-state synchronisation. Scientific Reports, 6, Article number: 37384. https://doi.org/10.1038/srep37384
2-year Impact Factor: 4.259|2016
Times cited: 19|2025-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Twins / Depression / Cerebellum / Functional magnetic resonance imaging (fMRI)

Environmental factors linked to depression vulnerability are associated with altered cerebellar resting-state synchronisation

Environmental factors linked to depression vulnerability are associated with altered cerebellar resting-state synchronisation

DocumentThe role of the cerebellum in adaptation: ALE meta-analyses on sensory feedback error2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-238
Location: BF-GMS
Title:
238 - When prediction errs: Examining the brain dynamics of altered saliency in self-voice perception
Duration: 2017-03 - 2020-01
Researcher(s):
Ana Pinheiro, Sonja Kotz, Michael Schwartze
Institution(s): Faculdade de Psicologia da Universidade de Lisboa (Portugal); Faculty of Psychology and Neuroscience, University of Maastricht (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Pinheiro, A. P.
Secondary author(s):
Kotz, S., Schwartz, M.
Number of reproductions:
1
Keywords:
Self-voice / Prediction / Saliency / Electroencephalogram (EEG) / Psychophysiology

Reference code: PT/FB/BL-2016-238.04
Location: BF-GMS
Title:
The role of the cerebellum in adaptation: ALE meta-analyses on sensory feedback error
Publication year: 2019
URL:
https://onlinelibrary.wiley.com/doi/full/10.1002/hbm.24681
Abstract/Results: ABSTRACT:
It is widely accepted that unexpected sensory consequences of self-action engage the cerebellum. However, we currently lack consensus on where in the cerebellum, we find fine-grained differentiation to unexpected sensory feedback. This may result from methodological diversity in task-based human neuroimaging studies that experimentally alter the quality of self-generated sensory feedback. We gathered existing studies that manipulated sensory feedback using a variety of methodological approaches and performed activation likelihood estimation (ALE) meta-analyses. Only half of these studies reported cerebellar activation with considerable variation in spatial location. Consequently, ALE analyses did not reveal significantly increased likelihood of activation in the cerebellum despite the broad scientific consensus of the cerebellum's involvement. In light of the high degree of methodological variability in published studies, we tested for statistical dependence between methodological factors that varied across the published studies. Experiments that elicited an adaptive response to continuously altered sensory feedback more frequently reported activation in the cerebellum than those experiments that did not induce adaptation. These findings may explain the surprisingly low rate of significant cerebellar activation across brain imaging studies investigating unexpected sensory feedback. Furthermore, limitations of functional magnetic resonance imaging to probe the cerebellum could play a role as climbing fiber activity associated with feedback error processing may not be captured by it. We provide methodological recommendations that may guide future studies.
Accessibility: Document exists in file
Language:
eng
Author:
Johnson, J. F.
Secondary author(s):
Belyk, M., Schwartze, M., Pinheiro, A. P., Kotz, S. A.
Document type:
Article
Number of reproductions:
1
Percentiles:
5
Reference:
Johnson, J. F., Belyk, M., Schwartze, M., Pinheiro, A. P., & Kotz, S. A. (2019). The role of the cerebellum in adaptation: ALE meta-analyses on sensory feedback error. Human Brain Mapping, 40(13), 3966-3981. https://doi.org/10.1002/hbm.24681
2-year Impact Factor: 4.421|2019
Times cited: 22|2024-02-12
Indexed document: Yes
Quartile: Q1
Keywords: Cerebellum / fMRI / Forward model / Meta-analysis / Prediction / Sensory feedback

The role of the cerebellum in adaptation: ALE meta-analyses on sensory feedback error

The role of the cerebellum in adaptation: ALE meta-analyses on sensory feedback error

DocumentMicroglia-mediated remodelling of the cerebellar circuit2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-264
Location: BF-GMS
Title:
264 - The influence of maternal bonding in neuroimmune synaptic sculpting
Duration: 2017-01 - 2020-09
Researcher(s):
Ana Luísa Cardoso, João Peça, Joana Guedes, Ana Silvestre Cardoso, Ana Viegas, Elisabete Ferreiro
Institution(s): Center for Neuroscience and Cell Biology, University of Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Cardoso, A. L.
Secondary author(s):
Peça, J., Guedes, J., Cardoso, A. S., Viegas, A. , Ferreiro, E.
Number of reproductions:
1
Keywords:
Maternal bonding / Pre-frontal cortex / Synaptic pruning / Neuroimmunity / Psychophysiology

Reference code: PT/FB/BL-2016-264.05
Location: BF-GMS
Title:
Microglia-mediated remodelling of the cerebellar circuit
Publication year: 2019
URL:
http://hdl.handle.net/10316/87855
Abstract/Results: ABSTRACT:
Despite great advances in neuroscience research, knowledge on the mechanisms behind the origin of neuropsychiatric disorders, as well as possible therapies, are still lacking. Recently, the neuroimmune system has been studied in the context of these diseases, with emphasis given to microglia, due to their role in brain development. Microglia are known to regulate the pool of neuronal precursors and aid in neuronal circuit formation, as well as having a role in brain homeostasis in adulthood. Microglia constantly scan the brain for potential threats, undergoing immune activation in response to varied stimuli, then triggering inflammatory processes. In the context of neuropsychiatric diseases, activated microglia have been found in the brain of patients. Moreover, microglia dysfunction in critical periods of brain maturation has been hypothesized to contribute to circuitry alterations underlying these disorders.Microglia are heterogenous throughout different brain regions. Due to particularities of microglia in the cerebellum, including an enhanced clearance phenotype and activation priming, and the involvement of this brain region in regulating motor and social behaviors, the main goal of this thesis was to understand if challenging microglia function in critical periods of cerebellar maturation contributes to circuitry and behavioral alterations. In this work, it was showed that the maturation of cerebellar microglia is heavily hindered by IL-4, a Th2 anti-inflammatory cytokine considered as neuroprotective in neurodegeneration. IL-4 injection in mice not only affected microglia morphology, density and distribution in the cerebellum, but also induced alterations in Purkinje cell connectivity, ultimately leading to long-lasting behavioral abnormalities, such as motor coordination deficits, enhanced mobility and altered sociability. This work highlights the vulnerability of cerebellar maturation to environmental stimuli during the second postnatal week.
Accessibility: Document does not exist in file
Language:
eng
Author:
Ferreira, P.
Document type:
Master's thesis
Number of reproductions:
1
Reference:
Ferreira, P. (2019). Microglia-mediated remodelling of the cerebellar circuit. (Master's thesis in Cellular and Molecular Biology, Faculdade de Ciências e Tecnologia da Universidade de Coimbra, Portugal). Retrieved from http://hdl.handle.net/10316/87855
Indexed document: No
Keywords: Microglia / Cerebellum / Development / Immune activation / Neuropsychiatric disorders

DocumentDistribution and relative abundance of S100 proteins in the brain of the APP23 Alzheimer's Disease model mice2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-343
Location: BF-GMS
Title:
343 - Proteotoxic insults and synaptic dysfunction in the aging brain
Duration: 2015-06 - 2019-01
Researcher(s):
Cláudio Emanuel Moreira Gomes, Andreas Martin Grabrucker, Joana Margarida Lopes da Silva Cristóvão, Sónia Cristina Alves Dickson Leal Solano
Institution(s): FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências (Portugal); Neurocenter of Ulm University (Germany)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Author: Gomes, C.
Secondary author(s):
Grabrucker, A., Cristóvão, J., Solano, S.
Number of reproductions:
1
Keywords:
Protein homeostasis / Brain biometals / Neuroinflammation / Synaptic Biochemistry / Psychophysiology

Reference code: PT/FB/BL-2014-343.14
Location: BF-GMS
Title:
Distribution and relative abundance of S100 proteins in the brain of the APP23 Alzheimer's Disease model mice
Publication year: 2019
URL:
https://www.frontiersin.org/articles/10.3389/fnins.2019.00640/full
Abstract/Results: ABSTRACT:
Increasing evidence links proteins of the S100 family to the pathogenesis of Alzheimer's disease (AD). S100 proteins are EF-hand calcium-binding proteins with intra- and extracellular functions related to regulation of proliferation, differentiation, apoptosis, and trace metal homeostasis, and are important modulators of inflammatory responses. For example, S100A6, S100A8, and S100B expression levels were found increased in inflammatory diseases, but also neurodegenerative disorders, and S100A8/A9 complexes may provide a mechanistic link between amyloid-beta (A beta) plaque formation and neuroinflammation. On the other hand, S100B, a proinflammatory protein that is chronically up-regulated in AD and whose elevation precedes plaque formation, was recently shown to suppress A beta aggregation. Here, we report expression of S100A6 and S100B in astrocytes and less so in neurons, and low level of expression of S100A8 in both neurons and glial cells in vitro. In vivo, S100A8 expression is almost absent in the brain of aged wildtype mice, while S100A6 and S100B are expressed in all brain regions and most prominently in the cortex and cerebellum. S100B seems to be enriched in Purkinje cells of the cerebellum. In contrast, in the brain of APP23 mice, a mouse model for Alzheimer's disease, S100B, S100A6, and S100A8 show co-localization with A beta plaques, compatible with astrocyte activation, and the expression level of S100A8 is increased in neural cells. While S100A6 and S100B are enriched in the periphery of plaques where less fibrillar is found, S100A8 is more intense within the center of the inclusion. In vitro assays show that, similarly to S100B, S100A6, and S100A8 also delay A beta aggregation suggesting a regulatory action over protein aggregation. We posit that elevated expression levels and overlapping spatial distribution of brain S100 proteins and plaques translates functional relationships between these inflammatory mediators and AD pathophysiology processes that uncover important molecular mechanisms linking the aggregation and neuroinflammation cascades.
Accessibility: Document exists in file
Language:
eng
Author:
Hagmeyer, S.
Secondary author(s):
Romão, M. A., Cristóvão, J. S., Vilella, A., Zoli, M., Gomes, C. M., Grabrucker, A. M.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Hagmeyer, S., Romão, M. A., Cristóvão, J. S., Vilella, A., Zoli, M., Gomes, C. M., & Grabrucker, A. M. (2019). Distribution and relative abundance of S100 proteins in the brain of the APP23 Alzheimer's disease model mice. Frontiers in Neuroscience, 13: 640. https://doi.org/10.3389/fnins.2019.00640
2-year Impact Factor: 3.707|2019
Times cited: 24|2024-02-12
Indexed document: Yes
Quartile: Q2
Keywords: S100A8 / S100A6 / S100B / Amyloid beta / Cerebellum / Aggregates / Zinc

Distribution and relative abundance of S100 proteins in the brain of the APP23 Alzheimer's Disease model mice

Distribution and relative abundance of S100 proteins in the brain of the APP23 Alzheimer's Disease model mice

DocumentMicroglia-dependent remodeling of neuronal circuits2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-266
Location: BF-GMS
Title:
266 - Early life stress and social hierarchies: The role of cortico-striatal circuits
Duration: 2017-01 - 2021-01
Researcher(s):
João Peça, Joana Guedes, Ana Luísa Cardoso, Mohammed Hussien, Lara Franco, Mário Carvalho
Institution(s): Center for Neuroscience and Cell Biology, University of Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Peça, J.
Secondary author(s):
Guedes, J., Cardoso, A. L., Hussien, M., Franco, L., Carvalho, M.
Number of reproductions:
1
Keywords:
Animal behavior / Social hierarchy / Stress / Optogenetics / Psychophysiology

Reference code: PT/FB/BL-2016-266.10
Location: BF-GMS
Title:
Microglia-dependent remodeling of neuronal circuits
Publication year: 2022
URL:
https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.15689
Abstract/Results: Abstract
Microglia are tissue-resident macrophages responsible for the surveillance, neuronal support, and immune defense of the brain parenchyma. Recently, the role played by microglia in the formation and function of neuronal circuits has garnered substantial attention. During development, microglia have been shown to engulf neuronal precursors and participate in pruning mechanisms while, in the mature brain, they influence synaptic signaling, provide trophic support and shape synaptic plasticity. Recently, studies have unveiled different microglial characteristics associated with specific brain regions. This emerging view suggests that the maturation and function of distinct neuronal circuits may be potentially associated with the molecular identity microglia adopts across the brain. Here, we review and summarize the known role of these cells in the thalamus, hippocampus, cortex, and cerebellum. We focus on in vivo studies to highlight the characteristics of microglia that may be important in the remodeling of these neuronal circuits and in relation to neurodevelopmental and neuropsychiatric disorders.
Accessibility: Document exists in file
Language:
eng
Author:
Guedes, J. R.
Secondary author(s):
Ferreira, P., Costa, J., Cardoso, A. L., Peça, J.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Guedes, J. R., Ferreira, P., Costa, J., Cardoso, A. L., & Peça, J. (2022). Microglia-dependent remodeling of neuronal circuits. Journal of Neurochemistry, 163(2), 74-93. https://doi.org/10.1111/jnc.15689
2-year Impact Factor: 4.700|2022
Times cited: 16|2024-02-15
Indexed document: Yes
Quartile: Q2
Keywords: Brain wiring / Cerebellum / Cortex / Hippocampus / Microglia / Neurodevelopment / Thalamus

Microglia-dependent remodeling of neuronal circuits

Microglia-dependent remodeling of neuronal circuits

DocumentMicroglia-dependent remodeling of neuronal circuits2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-264
Location: BF-GMS
Title:
264 - The influence of maternal bonding in neuroimmune synaptic sculpting
Duration: 2017-01 - 2020-09
Researcher(s):
Ana Luísa Cardoso, João Peça, Joana Guedes, Ana Silvestre Cardoso, Ana Viegas, Elisabete Ferreiro
Institution(s): Center for Neuroscience and Cell Biology, University of Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Cardoso, A. L.
Secondary author(s):
Peça, J., Guedes, J., Cardoso, A. S., Viegas, A. , Ferreiro, E.
Number of reproductions:
1
Keywords:
Maternal bonding / Pre-frontal cortex / Synaptic pruning / Neuroimmunity / Psychophysiology

Reference code: PT/FB/BL-2016-264.08
Location: BF-GMS
Title:
Microglia-dependent remodeling of neuronal circuits
Publication year: 2022
URL:
https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.15689
Abstract/Results: Abstract
Microglia are tissue-resident macrophages responsible for the surveillance, neuronal support, and immune defense of the brain parenchyma. Recently, the role played by microglia in the formation and function of neuronal circuits has garnered substantial attention. During development, microglia have been shown to engulf neuronal precursors and participate in pruning mechanisms while, in the mature brain, they influence synaptic signaling, provide trophic support and shape synaptic plasticity. Recently, studies have unveiled different microglial characteristics associated with specific brain regions. This emerging view suggests that the maturation and function of distinct neuronal circuits may be potentially associated with the molecular identity microglia adopts across the brain. Here, we review and summarize the known role of these cells in the thalamus, hippocampus, cortex, and cerebellum. We focus on in vivo studies to highlight the characteristics of microglia that may be important in the remodeling of these neuronal circuits and in relation to neurodevelopmental and neuropsychiatric disorders.
Accessibility: Document exists in the file
Language:
eng
Author:
Guedes, J. R.
Secondary author(s):
Ferreira, P., Costa, J., Cardoso, A. L., Peça, J.
Document type:
Article-d
Number of reproductions:
1
Reference:
Guedes, J. R., Ferreira, P., Costa, J., Cardoso, A. L., & Peça, J. (2022). Microglia-dependent remodeling of neuronal circuits. Journal of Neurochemistry, 163(2), 74-93. https://doi.org/10.1111/jnc.15689
2-year Impact Factor: 4.700|2022
Times cited: 16|2024-02-15
Indexed document: Yes
Quartile: Q2
Keywords: Brain wiring / Cerebellum / Cortex / Hippocampus / Microglia / Neurodevelopment / Thalamus

Microglia-dependent remodeling of neuronal circuits

Microglia-dependent remodeling of neuronal circuits

DocumentFinal report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.01
Location: BF-GMS
Title:
Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Publication year: 2018
Abstract/Results:
ABSTRACT:
BACKGROUND
Cognitive training (CT) has been widely implemented and it is currently accepted as the most promising method to alleviate cognitive decline. Several techniques have been combined with CT to explore the synergetic effects and, recently, a beneficial effect has been shown after the combination with transcranial direct current stimulation (tDCS).
AIMS
Here we combined multiple sessions CT with tDCS to assess verbal episodic memory improvement in healthy elderly subjects, compared with sham and a wait list group.
METHOD
We tested whether CT and excitatory tDCS over the left dorsolateral prefrontal cortex (lDLPFC) or right cerebellar cortex (rCC) facilitates verbal episodic memory, compared with sham stimulation and a wait list control group. CT was applied daily for 1 hour, after 20 minutes of tDCS, over 12 sessions. Performance on memory and other cognitive tasks was evaluated at baseline and postintervention, using behavioral and neuroimaging tools. Participants were healthy elderly, = 60 years, right-handed, without history of neuropsychiatric disease.
RESULTS
Data suggest an improvement in verbal episodic memory tasks in the groups receiving CT + tDCS. Interestingly, there is a greater improvement and consistency in the group receiving CT+ tDCS in the rCC. Neuroimaging data supports the results from the neuropsychological assessment. Specifically, tDCS over the right cerebellum + CT increased the functional connectivity in the left hippocampus.
CONCLUSIONS
These data suggest that CT and neuromodulation hold promise as a means to enhance cognitive functions in healthy elderly. Greater light is also shed on the role of the cerebellar cortex in cognitive processing.
Accessibility: Document exists in file
Language:
eng
Author:
Simões, M. R.
Secondary author(s):
Fernandes, F., Alves, J. E., Simis, M. , Martins, A. R., Almeida, J.
Document type:
Final report
Number of reproductions:
1
Reference:
Simões, M. R., Fernandes, F., Alves, J. E., Simis, M., Martins, A. R., & Almeida, J. (2018). Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly.
Indexed document: No
Keywords: Aging / Cognitive enhancement / tDCS / fMRI / Cerebellum

Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly

Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly

DocumentThe cerebellum is causally involved in episodic memory under aging2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.07
Location: BF-GMS
Title:
The cerebellum is causally involved in episodic memory under aging
Publication year: 2023
URL:
https://link.springer.com/article/10.1007/s11357-023-00738-0
Abstract/Results: ABSTRACT:
Episodic memory decline is a major signature of both normal and pathological aging. Many neural regions have been implicated in the processes subserving both episodic memory and typical aging decline. Here, we demonstrate that the cerebellum is causally involved episodic memory under aging. We show that a 12-day neurostimulation program delivered to the right cerebellum led to improvements in episodic memory performance under healthy aging that long outlast the stimulation period — healthy elderly individuals show episodic memory improvement both immediately after the intervention program and in a 4-month follow-up. These results demonstrate the causal relevance of the cerebellum in processes associated with long-term episodic memory, potentially highlighting its role in regulating and maintaining cognitive processing. Moreover, they point to the importance of non-pharmacological interventions that prevent or diminish cognitive decline in healthy aging.
Accessibility: Document exists in file
Language:
eng
Author:
Almeida, J.
Secondary author(s):
Martins, A. R., Amaral, L., Valério, D., Bukhari, Q., Schu, G., Nogueira, J., Spínola, M., Soleimani, G., Fernandes, F., Silva, A. R., Fregni, F., Simis, M., Simões, M., Peres, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Almeida, J., Martins, A. R., Amaral, L., Valério, D., Bukhari, Q., Schu, G., Nogueira, J., Spínola, M., Soleimani, G., Fernandes, F., Silva, A. R., Fregni, F., Simis, M., Simões, M., & Peres, A. (2023). The cerebellum is causally involved in episodic memory under aging. GeroScience, 45(4), 2267–2287. https://doi.org/10.1007/s11357-023-00738-0
2-year Impact Factor: 5.3|2023
Times cited: 2|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Episodic memory decline / Cerebellum / Neurostimulation

The cerebellum is causally involved in episodic memory under aging

The cerebellum is causally involved in episodic memory under aging

DocumentVariability in white matter structure relates to hallucination proneness2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-146
Location: BF-GMS
Title:
146 - The me and the I: Dissociating ownership and agency in sensorimotor processing
Duration: 2021/09
Researcher(s):
Ana Pinheiro, Sonja Kotz, Michael Schwartze
Institution(s): Centro de Investigação em Ciência Psicológica - CICPSI, Faculdade de Psicologia da Universidade de Lisboa (Portugal); Faculty of Psychology and Neuroscience, University of Maastricht (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Article
Language: eng
Notes:
Ongoing project
Author: Pinheiro, A. P.
Secondary author(s):
Kotz, S., Schwartze, M.
Number of reproductions:
1
Keywords:
Self / Agency / Ownership / Electroencephalogram (EEG) / Psychophysiology

Reference code: PT/FB/BL-2020-146.04
Location: BF-GMS
Title:
Variability in white matter structure relates to hallucination proneness
Publication year: 2024
URL:
https://doi.org/10.1016/j.nicl.2024.103643
Abstract/Results: ABSTRACT:
Hallucinations are a prominent transdiagnostic psychiatric symptom but are also prevalent in individuals who do not require clinical care. Moreover, persistent psychosis-like experience in otherwise healthy individuals may be related to an increased risk to transition to a psychotic disorder. This suggests a common etiology across clinical and non-clinical individuals along a multidimensional psychosis continuum that may be detectable in structural variations of the brain. The current diffusion tensor imaging study assessed 50 healthy individuals (35 females) to identify possible differences in white matter associated with hallucination proneness (HP). This approach circumvents potential confounds related to medication, hospitalization, and disease progression common in clinical individuals. We determined how HP relates to white matter structure in selected association, commissural, and projection fiber pathways putatively linked to psychosis. Increased HP was associated with enhanced fractional anisotropy (FA) in the right uncinate fasciculus, the right anterior and posterior arcuate fasciculus, and the corpus callosum. These findings support the notion of a psychosis continuum, providing first evidence of structural white matter variability associated with HP in healthy individuals. Furthermore, alterations in the targeted pathways likely indicate an association between HP-related structural variations and the putative salience and attention mechanisms that these pathways subserve.
Accessibility: Document exists in file
Language:
eng
Author:
Johnson, J. F.
Secondary author(s):
Schwartze, M., Belyk, M., Pinheiro, A. P., Kotz, S. A.
Document type:
Article
Number of reproductions:
1
Reference:
Johnson, J. F., Schwartze, M., Belyk, M., Pinheiro, A. P., & Kotz, S. A. (2024). Variability in white matter structure relates to hallucination proneness. NeuroImage Clinical, 43, 103643. https://doi.org/10.1016/j.nicl.2024.103643
2-year Impact Factor: 3.4|2023
Times cited: 0|2024-08-07
Indexed document: Yes
Quartile: Q2
Keywords: Diffusion tensor imaging / Hallucination / Psychosis-like experience / White matter / Cerebellum

Variability in white matter structure relates to hallucination proneness

Variability in white matter structure relates to hallucination proneness

File199 - The puzzle of self-tickling: From Darwin's observations to modern neuroscience insights

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2024
Location: BF-GMS
Title:
2024 Grants
Start date: 2025-01

Reference code: PT/FB/BL-2024-199
Location: BF-GMS
Title:
199 - The puzzle of self-tickling: From Darwin's observations to modern neuroscience insights
Researcher(s): Konstantina Kilteni, Tilman Stephani, Anne Hoffmann
Institution(s): Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen (The Netherlands)
Contents: Contents:
Application form
Correspondence
Language: eng
Notes:
This project has not started yet
Author: Kilteni, K.
Secondary author(s):
Stephani, T., Hoffmann, A.
Number of reproductions:
1
Keywords:
Tickling / Somatosensory cortex / Cerebellum / Laminar neuroimaging / Psychophysiology

DocumentDeconstructing the self and reshaping perceptions: An intensive whole-brain 7T MRI case study of the stages of insight during advanced investigative insight meditation2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-099
Location: BF-GMS
Title:
099 - Beyond "mindfulness" and toward a modern science of meditative mastery and spiritual transformation
Duration: 2021-03 - 2024-02
Researcher(s):
Matthew Sacchet, Diego Pizzagalli, Remko van Lutterveld, Marta Bianciardi
Institution(s): Center for Depression, Anxiety, and Stress Research - CDASR, McLean Hospital, Belmont (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Sacchet, M.
Secondary author(s):
Pizzagalli, D., van Lutterveld, R., Bianciardi, M.
Number of reproductions:
3
Keywords:
Advanced meditation / Enlightenment / Neuroimaging / Mindfulness meditation / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2020-099.19
Location: BF-GMS
Title:
Deconstructing the self and reshaping perceptions: An intensive whole-brain 7T MRI case study of the stages of insight during advanced investigative insight meditation
Publication year: 2024
URL:
https://doi.org/10.1016/j.neuroimage.2024.120968
Abstract/Results: ABSTRACT:
The stages of insight (SoI) are a series of psychological realizations experienced through advanced investigative insight meditation (AIIM). SoI provide a powerful structured framework of AIIM for understanding and evaluating insight-based meditative development through changes in perception, experiences of self, cognition, and emotional processing. Yet, the neurophenomenology of SoI remains unstudied due to methodological difficulties, rarity of suitable advanced meditation practitioners, and dominant research emphasis on attention-based meditative practices. We investigated the neurophenomenology of SoI in an intensively sampled adept meditator case study (4 hr 7T fMRI collected in 26 runs with concurrent phenomenology) who performed SoI and rated specific aspects of experience immediately thereafter. Linear mixed models and correlations were used to examine relations among the cortex, subcortex, brainstem, and cerebellum, and SoI phenomenology. We identified distinctive whole-brain activity patterns associated with specific SoI, and that were different from two non-meditative control states. SoI consistently deactivated regions implicated in self-related processing, including the medial prefrontal cortex and temporal poles, while activating regions associated with awareness and perception, including the parietal and visual cortices, caudate, several brainstem nuclei, and cerebellum. Patterns of brain activity related to affective processing and SoI phenomenology were also identified. Our study presents the first neurophenomenological evidence that SoI shifts and deconstructs self-related perception and conceptualization, and increases general awareness and perceptual sensitivity and acuity. Our study provides SoI as a foundation for investigative, and advanced meditation in particular.
Copyright/Reproduction: Document exists in file
Language:
eng
Author:
Yang, W. F. Z.
Secondary author(s):
Chowdhury, A., Sparby, T., Sacchet, M. D.
Document type:
Article
Number of reproductions:
3
Reference:
Yang, W. F. Z., Chowdhury, A., Sparby, T., & Sacchet, M. D. (2024). Deconstructing the self and reshaping perceptions: An intensive whole-brain 7T MRI case study of the stages of insight during advanced investigative insight meditation. NeuroImage, 305, 120968. Advance online publication. https://doi.org/10.1016/j.neuroimage.2024.120968
2-year Impact Factor: 4.70|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2025-01-06
Indexed document: Yes
Quartile: Q1
Keywords: Advanced meditation / Neurophenomenology / Stages of insight / 7T functional magnetic resonance imaging (fMRI) / Brainstem / Cerebellum

Deconstructing the self and reshaping perceptions: An intensive whole-brain 7T MRI case study of the stages of insight during advanced investigative insight meditation

Deconstructing the self and reshaping perceptions: An intensive whole-brain 7T MRI case study of the stages of insight during advanced investigative insight meditation

File402 - Future sight: The cerebellum's role in precognitive perception

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2024
Location: BF-GMS
Title:
2024 Grants
Start date: 2025-01

Reference code: PT/FB/BL-2024-402
Location: BF-GMS
Title:
402 - Future sight: The cerebellum's role in precognitive perception
Researcher(s): Gianluca Malatesta
Institution(s): Department of Psychology, Università degli Studi "G. d'Annunzio" Chieti-Pescara (Italy)
Contents: Contents:
Application form
Correspondence
Language: eng
Notes:
This project has not started yet
Author: Malatesta, G.
Number of reproductions:
3
Keywords:
Cerebellum / Precognition / Neuromodulation / Prediction / Psychophysiology and Parapsychology