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BIAL Foundation
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DE:"Circadian"
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Type Title Begin End
DocumentRelationship between post-awakening salivary cortisol and melatonin secretion in healthy participants2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-072
Location: Arquivo PCA - Pasta 8/2012
Title:
072 - The psychophysiology of human attachment and stress
Duration: 2013-10 - 2015-09
Researcher(s):
Angela Clow, Lisa Thorn, Andrea Oskis, Nina Smyth
Institution(s): Department of Psychology, University of Westminster, London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
2 Articles
Language: eng
Author:
Clow, A.
Secondary author(s):
Thorn, L., Oskis, A., Smyth, N.
Number of reproductions:
1
Keywords:
Psychophysiology / Affective and social behavior / Attachment / Psychoneuroimmunology / Endocrinology / Stress and health

Reference code: PT/FB/BL-2012-072.04
Location: Arquivo PCA - Pasta 8/2012
Title:
Relationship between post-awakening salivary cortisol and melatonin secretion in healthy participants
Publication year: 2016
URL:
http://www.tandfonline.com/doi/abs/10.3109/10253890.2016.1146671
Abstract/Results: ABSTRACT:
We report the relationship between patterns of post-awakening salivary melatonin and cortisol secretion in healthy participants (n=51; mean age 21.6 ± 5.0 years). Saliva samples were collected within the domestic setting, at 0, 15, 30 and 45 min post-awakening on 2 consecutive typical weekdays. Analyses were undertaken on data with electronically verified sample timing accuracy (<?5 min delay between awakening and the start of saliva sampling). Melatonin secretion declined linearly by an average of 29% within the first 45 minutes post-awakening. In contrast there was a marked 112% surge in cortisol, characteristic of the cortisol awakening response. No day-differences in melatonin or cortisol secretion were observed but melatonin concentrations were lower with later awakening. Despite contrasting post-awakening changes in these hormones there was a lack of relationship between overall levels or patterns of melatonin and cortisol during this period.
Accessibility: Document does not exist in file
Language:
eng
Author:
Ramachandran, N.
Secondary author(s):
Smyth, L., Thorn, L., Eardley, A., Evans, P., Clow, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Ramachandran, N., Smyth, N., Thorn, L., Eardley, A., Evans, P., & Clow, A. (2016). Relationship between post-awakening salivary cortisol and melatonin secretion in healthy participants. Stress: The International Journal on the Biology of Stress, 19(2), 260-263. https://doi.org/10.3109/10253890.2016.1146671
2-year Impact Factor: 2.590|2016
Times cited: 8|2024-02-07
Indexed document: Yes
Quartile: Q2
Keywords: Saliva / CAR / Awakening / Circadian / Biological dawn / Diurnal
File135 - The physiological role of circadian rhythms in memory2019-012023-01

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-135
Location: BF-GMS
Title:
135 - The physiological role of circadian rhythms in memory
Duration: 2019-01 - 2023-01
Researcher(s):
Luísa Lopes, Miguel Remondes, Ana Morgado, Joana Coelho
Institution(s): Instituto de Medicina Molecular - João Lobo Antunes, Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Lopes, L. V.
Secondary author(s):
Remondes, M., Morgado, A., Coelho, J.
Number of reproductions:
1
Keywords:
Psycophysiology / Cognition / Circadian / Memory
DocumentFinal report - The physiological role of circadian rhythms in memory2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-135
Location: BF-GMS
Title:
135 - The physiological role of circadian rhythms in memory
Duration: 2019-01 - 2023-01
Researcher(s):
Luísa Lopes, Miguel Remondes, Ana Morgado, Joana Coelho
Institution(s): Instituto de Medicina Molecular - João Lobo Antunes, Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Lopes, L. V.
Secondary author(s):
Remondes, M., Morgado, A., Coelho, J.
Number of reproductions:
1
Keywords:
Psycophysiology / Cognition / Circadian / Memory

Reference code: PT/FB/BL-2018-135.01
Location: BF-GMS
Title:
Final report - The physiological role of circadian rhythms in memory
Publication year: 2023
Abstract/Results:
ABSTRACT:
BACKGROUND
Circadian disruption impacts on cognition as seen in shift-work and manipulation of sleep-wake cycles in humans and rats. However, the functional interactions between Suprachiasmatic Nucleus (SCN) and memory-related regions, such as the Hippocampus (HIPP), have never been defined.
AIMS
We aimed at characterizating the structural connectivity between the SCN and the hippocampus durinh a circadian shift protocol METHOD
Whole-brain functional connectivity was modeled by combining 14C-2-deoxyglucose functional imaging and PLS Regression (Dawson et al, 2014) on male rats (13 week-old) under a normal circadian cycle or after 4 cycles of repeated phase shifts and recovery sessions (Craig et al, 2008).
RESULTS
Upon analysis of 67 brain regions, we found alterations in the metabolic activity of SCN and the HIPP, Medial Entorhinal Cortex (MEC), Perirhinal Cortex and Dorsal Raphe´ (DR). We then modeled the relationship between the activity of these seed regions and the remainder regions measured. A total of 127 functional connectivity interactions were impacted by the circadian shift, particularly a hypofunction of the MEC and related projections, and a hyperconnection of the DR and associated pathways.
Moreover, the shifted animals displayed a reduced performance in the Novel Object Recognition and Pattern Separation Task, whereas the performances in the Morris Water Maze and the Y-maze were preserved.
Relevant anatomical projections were traced by resorting to transsynaptic antero- and retrograde viral vectors, between the SCN and the HIPP, that revealed the Septum as a putative hub of circadian information onto the HIPP.
CONCLUSIONS
Altogether, these connectivity patterns suggest that circadian disturbance may induce adaptive mechanisms to preserve cognitive performance upon circadian insult.
Accessibility: Document exists in file
Language:
eng
Author:
Lopes, L. V.
Secondary author(s):
Remondes, M., Morgado, I., Coelho, J.
Document type:
Final report
Number of reproductions:
1
Reference:
Lopes, L. V., Remondes, M., Morgado, I., & Coelho, J. (2023). Final report - The physiological role of circadian rhythms in memory.
Indexed document: No
Keywords: Circadian / Cognition / Memory

Final report - The physiological role of circadian rhythms in memory

Final report - The physiological role of circadian rhythms in memory