Processing, please wait...
Database
search
in
Filter year from
to
Language
Country
  • Enter your search phrase in the search box.
  • General search:
    • The Boolean operator AND between the terms is assumed by default. If you enter the words European Union in the search box, the system returns all records in which both words occur, regardless of their order.
    • When entering a set of words in quotes, e.g "european union", all records containing the literal term "European Union" will be retrieved.
  • Search by access fields (e.g. author, title, etc.):
    • To direct your search, choose the field in which you want to search the word or expression.
    • Search in the field assumes by default the expression in quotes, e.g. European union will retrieve all records containing the literal term "European Union"
  • To perform more complex searches, additional words or expressions may be added.
  • If you want to refine the search results, you can always access the link "search" in the upper left corner of the page of search results.
  • The search engine is not case sensitive. For example, the word congress has the same meaning that Congress or CONGRESS.
  • To truncate your search expression, use the $ character
  • You can filter the results of your search by a date or date range, filling the appropriate boxes.
Base:
BIAL Foundation
Search:
DE:"Cognitive decline"
Results
1
to
5
from
5
found.
View
Selection Description
Type Title Begin End
DocumentTypicality as a critical dimension of semantic memory: convergence of cognitive and neural measures in young and old adults2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-089
Location: Arquivo PCA - Pasta 11/2012
Title:
089 - Interaction of medial and lateral temporal lobe in memory expression: insights from patient and fMRI data
Duration: 2013-04 - 2016-01
Researcher(s):
Ana Luísa Nunes Raposo, José Frederico Henzler Ferreira Marques, José Guilherme Cortez Pimentel
Institution(s): Faculdade de Psicologia, Universidade de Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Raposo, A.
Secondary author(s):
Marques, J., Pimentel, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Memory / Biopsychological problems / Diseases/Injuries / Epilepsy / Brain structure and function

Reference code: PT/FB/BL-2012-089.08
Location: Arquivo PCA - Pasta 11/2012
Title:
Typicality as a critical dimension of semantic memory: convergence of cognitive and neural measures in young and old adults
Publication year: 2015
URL:
http://www.appe.pt/past/2015/files/ProgramaPostersAPPE-2015.pdf
Abstract/Results: ABSTRACT:
Neste projeto exploramos a tipicidade dos conceitos como dimensão chave da memória semântica, combinando medidas comportamentais e imagiológicas em jovens e idosos saudáveis. Dados de fMRI com jovens adultos mostraram que a categorização de itens atípicos, relativamente a itens típicos, envolveu maior ativação dos lobos temporal anterior e frontal inferior, evidenciando a sinergia entre representação conceptual e controlo executivo na memória semântica. O estudo com idosos revelou que o declínio cognitivo (indexado pelo MoCA) prediz o aumento do efeito de tipicidade, indicando vulnerabilidade do sistema semântico com o envelhecimento. Os resultados enfatizam a cooperação entre representação conceptual e controlo cognitivo no processamento semântico. Estudos de neuroimagem em curso com idosos permitirão perceber quais as funções semânticas mais afetadas no envelhecimento.
Accessibility: Document exists in file
Language:
por
Author:
Alves, M.
Secondary author(s):
Raposo, A., Santi, A., Marques, J. F.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Alves, M., Raposo, A., Santi, A. & Marques, J. F. (2015). Typicality as a critical dimension of semantic memory: convergence of cognitive and neural measures in young and old adults. In Abstract book of 10º Encontro Anual da Associação Portuguesa de Psicologia Experimental (p.1). Universidade do Algarve: Faro, Portugal.
Indexed document: No
Keywords: Concept typicality / Categorization / Ageing / Cognitive decline

Typicality as a critical dimension of semantic memory: convergence of cognitive and neural measures in young and old adults

Typicality as a critical dimension of semantic memory: convergence of cognitive and neural measures in young and old adults

Poster

Poster

DocumentConcept typicality responses in the semantic network and along aging2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-089
Location: Arquivo PCA - Pasta 11/2012
Title:
089 - Interaction of medial and lateral temporal lobe in memory expression: insights from patient and fMRI data
Duration: 2013-04 - 2016-01
Researcher(s):
Ana Luísa Nunes Raposo, José Frederico Henzler Ferreira Marques, José Guilherme Cortez Pimentel
Institution(s): Faculdade de Psicologia, Universidade de Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Raposo, A.
Secondary author(s):
Marques, J., Pimentel, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Memory / Biopsychological problems / Diseases/Injuries / Epilepsy / Brain structure and function

Reference code: PT/FB/BL-2012-089.09
Location: Arquivo PCA - Pasta 11/2012
Title:
Concept typicality responses in the semantic network and along aging
Publication year: 2015
Accessibility:
Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Raposo, A.
Secondary author(s):
Alves, M., Santi, A.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Raposo, A., Alves, M. & Santi, A. (2015, September). Concept typicality responses in the semantic network and along aging. Poster presented at the 19th Meeting of the European Society for Cognitive Psychology. Pafos, Chipre.
Indexed document: No
Keywords: Concept typicality / Categorization / Ageing / Cognitive decline

Poster

Poster

DocumentPredictors of cognitive stability or decline during aging: A longitudinal study in primary care2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-063
Location: Arquivo PCA - Pasta 9/2010
Title:
063 - Mindful ageing. Avoiding age related cognitive decline
Duration: 2011-04 - 2014-07
Researcher(s):
Isabel Pavão Martins, Nuno Lunet, Carolina Maruta, Clara Loureiro, Vanda Freitas, Joana Morgado, Sofia Reimão, Joana Tavares
Institution(s): Laboratório de Estudos de Linguagem, Unidade Neurologica de Investigação Clínica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Universidade de Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Language: eng / por
Author:
Martins, I. P.
Secondary author(s):
Lunet, N., Maruta, C., Loureiro, C., Freitas, V., Morgado, J., Reimão, S., Tavares, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Cognitive processes / Biopsychological problems / Neurodegenerative disorders / Dementia / Mild cognitive impairment (MCI) / Assessment tools / Brain structure and function

Reference code: PT/FB/BL-2010-063.02
Location: SEC PCA - 63/10
Title:
Predictors of cognitive stability or decline during aging: A longitudinal study in primary care
Publication year: 2018
URL:
https://www.tandfonline.com/doi/abs/10.1080/23279095.2018.1476866
Abstract/Results: ABSTRACT:
We aimed to identify the early predictors of cognitive decline, and primary care physicians’ (PCP) ability to diagnose cognitively impaired subjects, in a cohort of individuals recruited in primary care centers. Independent adults, aged =50?years at inception, with an overall low level of education, undertook a prospective clinical and cognitive evaluation targeting memory, attention and executive functions. At follow-up subjects were classified as cognitively normal (CN) or impaired (CI). Of 275 subjects (70.4?±?8.3?years old, 176 females, 7.5?±?4.4 education, 162 with MRI), 31 (11.2%) presented CI 4.9?years later, the majority (64.5%) presenting subjective cognitive complaints. PCP could correctly identify 40% of CI individuals, particularly if they presented current cognitive complaints. Male sex (OR =?3.117; CI95%: 1.007–9.645), age (OR =?1.063; CI95%: 1.004–1.126) and baseline scores on TMT-B (OR =?0.225; CI95%: 0.073–0.688) and Vocabulary (OR =??0.940; 95% CI: 0.894–0.986) predicted CI. This study shows that measures indicating poor cognitive reserve and low executive performance (as shown by low vocabulary and executive test scores, respectively) can be early indicators of the risk of decline, stressing the role of cognitive assessment as part of prevention/early intervention programs. The results also underline the need to help PCP to improve the detection of subjects with cognitive decline.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Martins, I. P.
Secondary author(s):
Maruta, C., Morgado, J., Loureiro, C., Tavares, J., Freitas, V., Lunet, N., Viana, P., Marques, P.
Document type:
Article
Number of reproductions:
1
Percentiles:
7|2022-03-19
Reference:
Martins, I. P., Maruta, C., Morgado, J., Loureiro, C., Tavares, J., Freitas, V., Lunet, N., Viana, P., & Marques, P. (2018). Predictors of cognitive stability or decline during aging: A longitudinal study in primary care. Applied Neuropsychology: Adult, 5, 1-13. doi: 10.1080/23279095.2018.1476866
2-year Impact Factor: 1.548|2018
Times cited: 4|2022-10-28
Indexed document: Yes
Quartile: Q3
Keywords: Cognitive aging / Cognitive decline / Primary care diagnosis / Risk factors for dementia

DocumentMay subjective language complaints predict future language decline in community-dwelling subjects?2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-063
Location: Arquivo PCA - Pasta 9/2010
Title:
063 - Mindful ageing. Avoiding age related cognitive decline
Duration: 2011-04 - 2014-07
Researcher(s):
Isabel Pavão Martins, Nuno Lunet, Carolina Maruta, Clara Loureiro, Vanda Freitas, Joana Morgado, Sofia Reimão, Joana Tavares
Institution(s): Laboratório de Estudos de Linguagem, Unidade Neurologica de Investigação Clínica, Faculdade de Medicina de Lisboa e Instituto de Medicina Molecular, Universidade de Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Language: eng / por
Author:
Martins, I. P.
Secondary author(s):
Lunet, N., Maruta, C., Loureiro, C., Freitas, V., Morgado, J., Reimão, S., Tavares, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Cognitive processes / Biopsychological problems / Neurodegenerative disorders / Dementia / Mild cognitive impairment (MCI) / Assessment tools / Brain structure and function

Reference code: PT/FB/BL-2010-063.04
Location: SEC PCA - 63/10
Title:
May subjective language complaints predict future language decline in community-dwelling subjects?
Publication year: 2019
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722202/
Abstract/Results: ABSTRACT:
Subjective cognitive complaints are rather prevalent in the elderly population and are associated with an increased risk of cognitive impairment and dementia. However, the predictive role of specific types of cognitive complaints has been less systematically assessed. The aim of the present study is to examine the predictive value of language complaints for cognitive and language decline in a cohort of community-dwelling healthy older adults, followed longitudinally over a 5-year period. A total of 402 subjects were enrolled in a prospective longitudinal study on aging and cognition. Participants answered a cognitive complaints questionnaire including two questions directed to language and were classified at baseline as having "Language Complaints" (LC) or "No Language Complaints" (NLC). They also performed a neuropsychological assessment tackling attention/processing speed, memory, executive functioning, and language at baseline. From these, 275 (68.4%) participated in a follow-up evaluation 4.9 (+/- 0.6) years later. At re-evaluation, subjects had a mean age of 70.4 (+/- 8.3) years, 7.5 (+/- 4.4) years of education, and 63.3% were female. Multivariate linear regression analysis was used to investigate whether language complaints at baseline predicted poorer language performance at follow-up or increased the risk of cognitive decline, with correction for sex, depressive symptoms, living status, baseline performance, and composite memory and executive performance. Results indicated that LC subjects had significantly worse performances than NLC subjects on semantic fluency 5 years later, but with a similar rate of decline overtime that was not associated with a follow-up outcome of cognitive decline/dementia. Language difficulties may represent a specific type of age-related cognitive complaints. Longer follow-ups are necessary to understand if they are associated with an increased risk of language or cognitive decline.
Accessibility: Document exists in file
Language:
eng
Author:
Maruta, C.
Secondary author(s):
Martins, I. P.
Document type:
Article
Number of reproductions:
1
Percentiles:
7|2022-03-19
Reference:
Maruta, C., & Martins, I. P. (2019). May Subjective Language Complaints Predict Future Language Decline in Community-Dwelling Subjects? Frontiers in Psychology, 10: 1974. doi: 10.3389/fpsyg.2019.01974
2-year Impact Factor: 2.067|2019
Times cited: 2|2022-10-28
Indexed document: Yes
Quartile: Q2
Keywords: Cognitive decline / Aging / Verbal fluency / Subjective language complaints / Subjective memory complaints questionnaire

May subjective language complaints predict future language decline in community-dwelling subjects?

May subjective language complaints predict future language decline in community-dwelling subjects?

DocumentThe old guard: age-related changes in microglia and their consequences2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-264
Location: BF-GMS
Title:
264 - The influence of maternal bonding in neuroimmune synaptic sculpting
Duration: 2017-01 - 2020-09
Researcher(s):
Ana Luísa Cardoso, João Peça, Joana Guedes, Ana Silvestre Cardoso, Ana Viegas, Elisabete Ferreiro
Institution(s): Center for Neuroscience and Cell Biology, University of Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Cardoso, A. L.
Secondary author(s):
Peça, J., Guedes, J., Cardoso, A. S., Viegas, A. , Ferreiro, E.
Number of reproductions:
1
Keywords:
Maternal bonding / Pre-frontal cortex / Synaptic pruning / Neuroimmunity / Psychophysiology

Reference code: PT/FB/BL-2016-264.07
Location: BF-GMS
Title:
The old guard: age-related changes in microglia and their consequences
Publication year: 2021
URL:
https://www.sciencedirect.com/science/article/pii/S0047637421000841
Abstract/Results: ABSTRACT:
Among all major organs, the brain is one of the most susceptible to the inexorable effects of aging. Throughout the last decades, several studies in human cohorts and animal models have revealed a plethora of age-related changes in the brain, including reduced neurogenesis, oxidative damage, mitochondrial dysfunction and cell senescence. As the main immune effectors and first responders of the nervous tissue, microglia are at the center of these events. These cells experience irrevocable changes as a result from cumulative exposure to environmental triggers, such as stress, infection and metabolic dysregulation. The age-related immunosenescent phenotype acquired by microglia is characterized by profound modifications in their transcriptomic profile, secretome, morphology and phagocytic activity, which compromise both their housekeeping and defensive functions. As a result, aged microglia are no longer capable of establishing effective immune responses and sustaining normal synaptic activity, directly contributing to age-associated cognitive decline and neurodegeneration. This review discusses how lifestyle and environmental factors drive microglia dysfunction at the molecular and functional level, also highlighting possible interventions to reverse aging-associated damage to the nervous and immune systems.
Accessibility: Document exists in file
Language:
eng
Author:
Costa, J.
Secondary author(s):
Martins, S., Ferreira, P., Cardoso, A. M. S., Guedes, J. R., Peça, J. M., Cardoso, A. L.
Document type:
Article
Number of reproductions:
1
Percentiles:
4|2022-03-19
Reference:
Costa, J., Martins, S., Ferreira, P., Cardoso, A. M. S., Guedes, J. R., Peça, J. M., & Cardoso, A. L. (2021). The old guard: age-related changes in microglia and their consequences. Mechanisms of Ageing and Development, 19: 111512. doi: 10.1016/j.mad.2021.111512
2-year Impact Factor: 5.498|2021
Times cited: 12|2022-10-30
Indexed document: Yes
Quartile: Q1
Keywords: Aging / Stress / Infection / Cognitive decline / Neuroimmune system / Microglia / Inflammation

The old guard: age-related changes in microglia and their consequences

The old guard: age-related changes in microglia and their consequences