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File051 - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach2017-032020-03

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-051
Location: BF-GMS
Title:
051 - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach
Duration: 2017-03 - 2020-03
Researcher(s):
Carlo Miniussi, Romina Esposito
Institution(s): Centre for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto (Italy)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Author: Miniussi, C.
Secondary author(s):
Esposito, R.
Number of reproductions:
1
Keywords:
Cognitive plasticity / Connectivity / Memory / Neuromodulation / Psychophysiology

File286 - Getting the aging brain to train: A working memory and neurostimulation approach2017-062023-03

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-286
Location: BF-GMS
Title:
286 - Getting the aging brain to train: A working memory and neurostimulation approach
Duration: 2017-06 - 2023-03
Researcher(s):
Adriana Sampaio, Ana Teixeira Santos, Sandra Carvalho, Jorge Leite, Ana Raquel, Felipe Fregni
Institution(s): Psychology Research Center (CIPsi), School of Psychology, University of Minho, Braga (Portugal); Spaulding-Labuschange Neuromodulation Center, Spaulding Rehabilitation Hospital & Massachusetts General Hospital/Harvard Medical School, Charlestown (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Sampaio, A.
Secondary author(s):
Teixeira-Santos, A. C., Carvalho, S., Leite, J., Mesquita, A. R., Fregni, F.
Number of reproductions:
1
Keywords:
Working memory training / Aging / Brain plasticity / Cognitive plasticity / Psychophysiology

DocumentReviewing working memory training gains in healthy older adults: A meta-analytic review of transfer for cognitive outcomes2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-286
Location: BF-GMS
Title:
286 - Getting the aging brain to train: A working memory and neurostimulation approach
Duration: 2017-06 - 2023-03
Researcher(s):
Adriana Sampaio, Ana Teixeira Santos, Sandra Carvalho, Jorge Leite, Ana Raquel, Felipe Fregni
Institution(s): Psychology Research Center (CIPsi), School of Psychology, University of Minho, Braga (Portugal); Spaulding-Labuschange Neuromodulation Center, Spaulding Rehabilitation Hospital & Massachusetts General Hospital/Harvard Medical School, Charlestown (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Sampaio, A.
Secondary author(s):
Teixeira-Santos, A. C., Carvalho, S., Leite, J., Mesquita, A. R., Fregni, F.
Number of reproductions:
1
Keywords:
Working memory training / Aging / Brain plasticity / Cognitive plasticity / Psychophysiology

Reference code: PT/FB/BL-2016-286.02
Location: BF-GMS
Title:
Reviewing working memory training gains in healthy older adults: A meta-analytic review of transfer for cognitive outcomes
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/pii/S0149763418308509?via%3Dihub
Abstract/Results: ABSTRACT
The objective of this meta-analytic review was to systematically assess the effects of working memory training on healthy older adults. We identified 552 entries, of which 27 experiments met our inclusion criteria. The final database included 1130 participants. Near- and far-transfer effects were analysed with measures of short-term memory, working memory, and reasoning. Small significant and long-lasting transfer gains were observed in working memory tasks. Effects on reasoning was very small and only marginally significant. The effects of working memory training on both near and far transfer in older adults were moderated by the type of training tasks; the adopted outcome measures; the training duration; and the total number of training hours. In this review we provide an updated review of the literature in the field by carrying out a robust multi-level meta-analysis focused exclusively on WMT in healthy older adults. Recommendations for future research are suggested.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Teixeira-Santos, A. C.
Secondary author(s):
Moreira, C. S., Magalhães, R., Magalhães, C., Pereira, D. R., Leite, J., Carvalho, S., Sampaio, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Teixeira-Santos, A. C., Moreira, C. S., Magalhães, R., Magalhães, C., Pereira, D. R., Leite, J., Carvalho, S., & Sampaio, A. (2019). Reviewing working memory training gains in healthy older adults: A meta-analytic review of transfer for cognitive outcomes. Neuroscience & Biobehavioral Reviews, 103, 163-177. https://doi.org/10.1016/j.neubiorev.2019.05.009
2-year Impact Factor: 8.330|2019
Times cited: 47|2024-02-12
Indexed document: Yes
Quartile: Q1
Keywords: Meta-analysis / Working memory training / Cognitive plasticity / Training transfer / Healthy older adults / Healthy ageing

DocumentFinal report - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-051
Location: BF-GMS
Title:
051 - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach
Duration: 2017-03 - 2020-03
Researcher(s):
Carlo Miniussi, Romina Esposito
Institution(s): Centre for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto (Italy)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Author: Miniussi, C.
Secondary author(s):
Esposito, R.
Number of reproductions:
1
Keywords:
Cognitive plasticity / Connectivity / Memory / Neuromodulation / Psychophysiology

Reference code: PT/FB/BL-2016-051.01
Location: BF-GMS
Title:
Final report - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach
Publication year: 2019
URL:
https://www.bial.com/media/3215/cognitive-plasticity-modulation-and-monitoring-through-a-neurophysiological-approach.pdf
Abstract/Results: ABSTRACT:
In the first phase we tested the effects of different tES protocols in visuo-spatial contextual learning (VSCL).
The study comprised three sessions designed to evaluate tDCS-induced changes in VSCL measures collected during the execution of a visual search task widely used to examine statistical learning in the visuo-spatial domain. In Experiment1 (E1), we probed for the effects of left-posterior parietal cortex (PPC) anodal-tDCS (AtDCS) at different timings (offline and online) and intensities (3mA, 1.5mA). The protocol producing the more robust effect in E1 was used in E2 with a swapped electrodes montage, while In E3, left-PPC 3mA cathodal-tDCS (CtDCS) was applied offline and online to investigate the effects on neuronal excitability reduction on VSCL.
Results revealed that high intensity offline AtDCS reduced VSCL regardless of the stimulation side (E1 & 2), while no significant behavioural changes were produced by both online AtDCS protocols (E1) and offline/online CtDCS (E3). The reduced VSCL could result from homeostatic mechanisms produced by the interaction of two excitability-increasing events hindering normal task-related neuroplastic phenomena.
In the second phase of project, we examined the neurophysiological correlates of modified cognitive performance by 3mA anodal-tDCS offline on left-posterior parietal cortex (PPC).
We acquired various electrophysiological measures in order to fully investigate the neural modifications induced by the application of the tES protocol producing the more robust effect in the first phase of the project. Electrophysiological measures were recorded both during the execution of the behavioural task (ERP measures) and during TMS-EEG co-registration at three different intervals (before tDCS (TEP1), after tDCS but before task (TEP2) and after task (TEP3)).
ERPs revealed a significant difference in the amplitude of N1 and P3 and this modulation could be interpreted as a general memory-mediated attentional capture produced by visual contexts that were repeated over time. Interestingly, Real-tDCS also produced a strong significant increase in the amplitude of the posterior P2 component in response to both repeated and not-repeated visual contexts. This modulation could reflect a stimulation dependent reduction of perceived saliency associated with the presentation of the visual search arrays. TMS-evoked potentials show that the only application of tDCS does not produce changes in connectivity, but there is a different pattern between real and sham conditions when participants are also asked to perform a cognitive task and it improves with time. Furthermore, the difference between TEP 1 and TEP 3 in sham condition, and not in the real one, suggests a reduction of cortical activation after real stimulation.
Accessibility: Document exists in file
Language:
eng
Author:
Miniussi, C.
Document type:
Final report
Number of reproductions:
1
Reference:
Miniussi, C. (2019). Final report - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach.
Indexed document: No
Keywords: Cognitive plasticity / Connectivity / Memory / Neuromodulation

Final report - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach

Final report - Cognitive plasticity: Modulation and monitoring through a neurophysiological approach