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DocumentCommunity screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2006-035.07
Location: Arquivo PCA - Pasta 17/2006
Title:
Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years
Publication year: 2007
URL:
http://www.sciencedirect.com/science/article/pii/S0920996406004804
Abstract/Results: ABSTRACT:
Prospective longitudinal investigations are needed to identify causal processes leading to schizophrenia. However, there is presently no cost-effective way to identify children who are at risk of developing schizophrenia spectrum disorders: Although having a family history of schizophrenia is associated with elevated risk for developing spectrum disorders, the majority of individuals with schizophrenia do not have an afflicted relative. The present study aimed to test the feasibility of screening a community sample of children, aged 9 to 12 years, to identify children who experienced a triad of putative antecedents of schizophrenia that had been identified from previous research, including: (1) speech and/or motor development lags or problems; (2) social, emotional, or behavioural problems; and (3) psychotic-like-experiences (PLEs). 548 children and 264 caregivers completed questionnaires. 9.2% of boys and 4.1% of girls displayed the triad of antecedents. 58.9% of the children reported "certain experience" of one or more PLEs. The results suggest that questionnaire screening of community samples of children for the putative antecedents of schizophrenia spectrum disorders is feasible. Accuracy of identification will only be established by follow-up studies.
Accessibility: Document does not exist in file
Language:
eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Maughan, B., Murray, R., Rutter, M., Taylor, E.
Document type:
Article
Number of reproductions:
1
Percentiles:
95.87|3.75
Reference:
Laurens, K. R., Hodgins, S., Maughan, B., Murray, R., Rutter, M., & Taylor, E. (2007). Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9-12 years. Schizophrenia Research, 90(1-3), 130-146. https://doi.org/10.1016/j.schres.2006.11.006
2-year Impact Factor: 4.240|2007
Times cited: 197|2026-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Childhood / Antecedents / Schizophrenia / Community screening / Questionnaire
DocumentGrey matter abnormalities in children aged 9–13 years presenting antecedents of schizophrenia: a voxel-based morphometry study2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2006-035.09
Location: Arquivo PCA - Pasta 17/2006
Title:
Grey matter abnormalities in children aged 9–13 years presenting antecedents of schizophrenia: a voxel-based morphometry study
Publication year: 2010
URL:
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-7893.2010.00230.x/abstract
Abstract/Results: ABSTRACT:
BACKGROUND:
Voxel-based morphometry (VBM) studies have identified widespread grey matter abnormalities in individuals with schizophrenia and less extensive abnormalities in first-episode patients and high-risk individuals defined by familial/genetic vulnerability or ultra high-risk criteria (Chan et al., in press. Schizophrenia Bulletin). Using a novel community screening method, we identified children who present multiple putative antecedents of schizophrenia (ASz) who may bear elevated risk for developing the disorder. We aimed to determine whether ASz children show grey matter abnormalities relative to typically-developing (TD) children with no antecedents.
METHODS:
Thirty TD (Mage = 10.6 years) and nineteen ASz (Mage = 10.5 years) children completed structural MRI scanning (3T GE). Paediatric templates were created from sample demographics (age and gender) using the Template-O-Matic toolbox (Wilke et al, 2008; NeuroImage 41: 903–913). Differences in grey matter volume (GMV) and concentration (GMC) were examined using VBM methods implemented in Statistical Parametric Mapping (SPM5).
RESULTS:
GMC and GMV were signifi cantly decreased (P < 0.01, corrected) in ASz children in the right middle frontal gyrus and increased in the left superior temporal gyrus, relative to TD children. Additionally, signifi cant GMC decreases were apparent in ASz children in the right inferior frontal and left precentral gyrii.
CONCLUSIONS:
ASz children aged 9–13 years show grey matter abnormalities in frontal and temporal brain regions that are consistent with those
observed in adults with schizophrenia. Furthermore, individuals with schizophrenia have been shown to experience functional abnormality in these same regions during working memory, inhibition and motor function tasks and during auditory hallucinations.
Accessibility: Document does not exist in file
Language:
eng
Author:
Cullen, A. E.
Secondary author(s):
Brito, S., Gregory, S., Williams, S., Murray, R., Hodgins, S., Laurens, K. R.
Document type:
Abstract
Number of reproductions:
1
Reference:
Cullen, A. E., Brito, S., Gregory, S., Williams, S., Murray, R., Hodgins, S., & Laurens, K. R. (2010). Grey matter abnormalities in children aged 9–13 years presenting antecedents of schizophrenia: a voxel-based morphometry study. POSTER ABSTRACTS. Early Intervention in Psychiatry, 4(Suppl. 1), 45. https://doi.org/10.1111/j.1751-7893.2010.00230.x
Indexed document: Yes
Keywords: Childhood / Antecedents / Schizophrenia / Community screening / Grey matter abnormalities

Grey matter abnormalities in children aged 9–13 years presenting antecedents of schizophrenia: a voxel-based morphometry study

Grey matter abnormalities in children aged 9–13 years presenting antecedents of schizophrenia: a voxel-based morphometry study
DocumentCharacterising putatively "at-risk" children who present psychotic-like experiences and other antecedents of schizophrenia2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2006-035.11
Location: Arquivo PCA - Pasta 17/2006
Title:
Characterising putatively "at-risk" children who present psychotic-like experiences and other antecedents of schizophrenia
Publication year: 2010
Abstract/Results:
ABSTRACT:
BACKGROUND:
Recognising and intervening with individuals at risk for schizophrenia prior to illness onset may minimise or prevent disability, but elucidating risk status is challenging. We have developed a novel method of screening community samples to identify children who present multiple putative antecedents of schizophrenia that distinguish individuals who later develop illness from those who do not [1].
METHODS:
We used questionnaires to identify children, aged 9-12 years, who present a triad of antecedents, namely: (i) psychotic-like experiences [PLEs]; (ii) a speech/motor development delay or abnormality; and (iii) a social, emotional, or behavioural problem.
RESULTS:
Data from 1,347 child and caregiver dyads indicate that 9.5% (13.2% boys, 6.1% girls) present the antecedent triad. Among these, 69% report experiencing distress or impairment associated with PLEs. Only longitudinal follow-up can ascertain the degree to which the triad predicts later schizophrenia, yet, we have established that these children already present features present in schizophrenia, including: (i) brain dysfunction during event-related potential (ERP) recordings of error processing and of involuntary attention orienting; (ii) similar neurocognitive deficits as observed in prodromal and first-episode samples; (iii) increased involuntary dyskinetic movements of the face and upper body; (iv) fewer positive and more negative parenting experiences; and (v) triad prevalence is elevated among UK children of African-Caribbean
and black African ethnicity, mimicking the increased prevalence of schizophrenia among these groups in the UK.
CONCLUSIONS:
These children may constitute appropriate targets for preventive interventions for schizophrenia. Longitudinal follow-up of the children, with additional measures, is ongoing.
Reference 1. Laurens K et al. Schizophr. Res. 2007;90:130–146.
Accessibility: Document does not exist in file
Language:
eng
Author:
Laurens, K. R.
Secondary author(s):
Taylor, E., Hodgins, S., Murray, R.
Document type:
Abstract
Number of reproductions:
1
Reference:
Laurens, K. R., Taylor, E., Hodgins, S., & Murray, R. (2010). Characterising putatively "at-risk" children who present psychotic-like experiences and other antecedents of schizophrenia. Australian and New Zealand Journal of Psychiatry, 44(Supplement 1), A22-A23.
Indexed document: Yes
Keywords: Childhood / Antecedents / Schizophrenia / Community screening / Preventive interventions
DocumentPsychometric comparability of self-report by children aged 9–10 versus 11 years on the Strengths and Difficulties Questionnaire (SDQ)2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

Reference code: PT/FB/BL-2012-194.10
Location: Arquivo PCA - Pasta 25/2012
Title:
Psychometric comparability of self-report by children aged 9–10 versus 11 years on the Strengths and Difficulties Questionnaire (SDQ)
Publication year: 2020
URL:
https://link.springer.com/article/10.1007/s12187-019-09633-7
Abstract/Results: ABSTRACT
The 25-item Strengths and Difficulties Questionnaire (SDQ) is a popular screening instrument that assesses childhood psychopathology and prosocial behaviour. While the value of acquiring multi-informant perspectives in the assessment of childhood psychopathology is recognised, the use of the self-report version of the questionnaire is recommended only for children aged 11 years and older. This study aimed to evaluate the psychometric comparability of self-report on the SDQ by children aged 9–10 years relative to children aged 11 years using item response modelling. Item response models were used in a community sample of 7959 children to investigate the structure, item characteristics, and age differences related to self-report by children aged 9–10 years (n?=?6004), relative to children aged 11 years (n?=?1955), on the SDQ. Internalizing, externalizing, and prosocial factors explained the covariance of the questionnaire items. There were statistically significant age-related differences on only two items (the “worries” and “distractible” items), but these differences were small in magnitude and did not affect the precision of measurement of the SDQ. Self-report by children aged 9 and 10 years on the SDQ is psychometrically comparable to reports by children aged 11 years after controlling for differences in latent severity. This work expands the utility of the self-report SDQ to children aged as young as 9 years.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2006-036.19
Author: Hobbs, M.
Secondary author(s):
Laurens, K.
Document type:
Article
Number of reproductions:
1
Percentiles:
73.72|0.97
Reference:
Hobbs, M., & Laurens, K. (2020). Psychometric comparability of self-report by children aged 9–10 versus 11 years on the Strengths and Difficulties Questionnaire (SDQ). Child Indicators Research, 3, 301–318. https://doi.org/10.1007/s12187-019-09633-7
2-year Impact Factor: 2.420|2020
Impact factor notes: Impact factor not available yet for 2020
Times cited: 9|2026-02-12
Indexed document: Yes
Quartile: Q2
Keywords: Differential item functioning / Latent structure / Development / Psychopathology / Community screening

DocumentPsychometric comparability of self-report by children aged 9–10 versus 11 years on the Strengths and Difficulties Questionnaire (SDQ)2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2006.035.29
Location: BF-GMS
Title:
Psychometric comparability of self-report by children aged 9–10 versus 11 years on the Strengths and Difficulties Questionnaire (SDQ)
Publication year: 2020
URL:
https://link.springer.com/article/10.1007/s12187-019-09633-7#citeas
Abstract/Results: Abstract
The 25-item Strengths and Difficulties Questionnaire (SDQ) is a popular screening instrument that assesses childhood psychopathology and prosocial behaviour. While the value of acquiring multi-informant perspectives in the assessment of childhood psychopathology is recognised, the use of the self-report version of the questionnaire is recommended only for children aged 11 years and older. This study aimed to evaluate the psychometric comparability of self-report on the SDQ by children aged 9–10 years relative to children aged 11 years using item response modelling. Item response models were used in a community sample of 7959 children to investigate the structure, item characteristics, and age differences related to self-report by children aged 9–10 years (n = 6004), relative to children aged 11 years (n = 1955), on the SDQ. Internalizing, externalizing, and prosocial factors explained the covariance of the questionnaire items. There were statistically significant age-related differences on only two items (the “worries” and “distractible” items), but these differences were small in magnitude and did not affect the precision of measurement of the SDQ. Self-report by children aged 9 and 10 years on the SDQ is psychometrically comparable to reports by children aged 11 years after controlling for differences in latent severity. This work expands the utility of the self-report SDQ to children aged as young as 9 years.
Accessibility: Document exists in file
Copyright/Reproduction:
by permission
Language:
eng
Related objects:
BL-2012.194.10
Author: Hobbs, M.
Secondary author(s):
Laurens, K.
Document type:
Article-d
Number of reproductions:
1
Percentiles:
73.72|0.97
Reference:
Hobbs, M., & Laurens, K. (2020). Psychometric comparability of self-report by children aged 9–10 versus 11 years on the Strengths and Difficulties Questionnaire (SDQ). Child Indicators Research, 3, 301–318. https://doi.org/10.1007/s12187-019-09633-7
2-year Impact Factor: 2.420|2020
Times cited: 9|2026-02-12
Indexed document: Yes
Quartile: Q2
Keywords: Differential item functioning / Latent structure / Development / Psychopathology / Community screening
DocumentIncreased likelihood of distressing and functionally impairing psychotic-like experiences among children with co-occurring internalising and externalising problems2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

Reference code: PT/FB/BL-2012-194.17
Location: BF-GMS
Title:
Increased likelihood of distressing and functionally impairing psychotic-like experiences among children with co-occurring internalising and externalising problems
Publication year: 2023
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0920996423000294?via%3Dihub
Abstract/Results: ABSTRACT:
Among children with psychotic-like experiences (PLEs), the presence of co-occurring psychopathology may distinguish children's self-report of clinically significant experiences (i.e., PLEs that are distressing and/or impairing of daily functioning) from reports of more benign experiences. The aim of this study was to examine whether the likelihood of distressing or impairing PLEs differed according to type of co-occurring psychopathology symptoms. A community sample of 5268 children aged 9-12 years were recruited from Greater London, UK. Participants completed the Psychotic-Like Experiences Questionnaire for Children, and the Strengths and Difficulties Questionnaire to measure internalising and externalising problems. Multinomial logistic regressions were used to determine the likelihood of PLEs being distressing and/or impairing (vs. not) among children with different co-occurring symptom profiles (PLEs only; PLEs with internalising problems only - PLE-I; PLEs with externalising problems only - PLE-E; and PLEs with both internalising and externalising problems - PLE-IE). Children with co-occurring internalising and/or externalising problems had greater odds of distressing and/or impairing PLEs compared to children without co-occurring psychopathology (PLEs only). These associations were moderate for PLE-E and strong for PLE-I and PLE-IE, with the greatest odds of distressing and impairing PLEs evident in the presence of internalising plus externalising comorbidities (odds ratios [with 99 % confidence intervals] for PLE-IE relative to PLE-I = 2.00 [1.34-2.99]; PLE-IE relative to PLE-E = 5.46 [3.78-7.90]). These results affirm the importance of screening for the presence and type of co-occurring psychopathology among children with PLEs to demarcate potentially different treatment needs.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2006.035.31
Author: Gutteridge, T. P.
Secondary author(s):
Kelly, A. B., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Reference:
Gutteridge, T. P., Kelly, A. B., & Laurens, K. R. (2023). Increased likelihood of distressing and functionally impairing psychotic-like experiences among children with co-occurring internalising and externalising problems. Schizophrenia Research, 252, 225-230. https://doi.org/10.1016/j.schres.2023.01.017
2-year Impact Factor: 3.6|2023
Times cited: 2|2025-09-26
Indexed document: Yes
Quartile: Q2
Keywords: Community screening / Developmental psychopathology / Early intervention / Middle childhood / Psychosis symptoms
DocumentIncreased likelihood of distressing and functionally impairing psychotic-like experiences among children with co-occurring internalising and externalising problems2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2006.035.31
Location: Arquivo PCA - Pasta 17/2006
Title:
Increased likelihood of distressing and functionally impairing psychotic-like experiences among children with co-occurring internalising and externalising problems
Publication year: 2023
URL:
https://www.sciencedirect.com/science/article/pii/S0920996423000294?via%3Dihub
Abstract/Results: ABSTRACT:
Among children with psychotic-like experiences (PLEs), the presence of co-occurring psychopathology may distinguish children's self-report of clinically significant experiences (i.e., PLEs that are distressing and/or impairing of daily functioning) from reports of more benign experiences. The aim of this study was to examine whether the likelihood of distressing or impairing PLEs differed according to type of co-occurring psychopathology symptoms. A community sample of 5268 children aged 9–12 years were recruited from Greater London, UK. Participants completed the Psychotic-Like Experiences Questionnaire for Children, and the Strengths and Difficulties Questionnaire to measure internalising and externalising problems. Multinomial logistic regressions were used to determine the likelihood of PLEs being distressing and/or impairing (vs. not) among children with different co-occurring symptom profiles (PLEs only; PLEs with internalising problems only – PLE-I; PLEs with externalising problems only – PLE-E; and PLEs with both internalising and externalising problems – PLE-IE). Children with co-occurring internalising and/or externalising problems had greater odds of distressing and/or impairing PLEs compared to children without co-occurring psychopathology (PLEs only). These associations were moderate for PLE-E and strong for PLE-I and PLE-IE, with the greatest odds of distressing and impairing PLEs evident in the presence of internalising plus externalising comorbidities (odds ratios [with 99 % confidence intervals] for PLE-IE relative to PLE-I = 2.00 [1.34–2.99]; PLE-IE relative to PLE-E = 5.46 [3.78–7.90]). These results affirm the importance of screening for the presence and type of co-occurring psychopathology among children with PLEs to demarcate potentially different treatment needs.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2012-194.17
Author: Gutteridge, T. P.
Secondary author(s):
Kelly, A. B., Laurens, K. R
Document type:
Article-d
Number of reproductions:
1
Reference:
Gutteridge, T. P., Kelly, A. B., & Laurens, K. R. (2023). Increased likelihood of distressing and functionally impairing psychotic-like experiences among children with co-occurring internalising and externalising problems. Schizophrenia Research, 252, 225-230. https://doi.org/10.1016/j.schres.2023.01.017
2-year Impact Factor: 3.6|2023
Times cited: 2|2025-09-26
Indexed document: Yes
Quartile: Q2
Keywords: Psychosis symptoms / Developmental psychopathology / Community screening / Middle childhood / Early intervention