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DocumentSynaptic competition in structural plasticity and cognitive function2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-161
Location: Arquivo PCA - Pastas 22/2010
Title:
161 - Investigating the function of synaptic competition in memory formation and mental retardation
Duration: 2011-09 - 2015-09
Researcher(s):
Inbal Israely, Anna Hobbiss, Ana Vaz
Institution(s): Champalimaud Foundation, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Israely, I.
Secondary author(s):
Hobbiss, A., Vaz, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes / Memory / Biopsychological problems / Childhood and adolescent disorders / Mental retardation

Reference code: PT/FB/BL-2010-161.02
Location: Arquivo PCA - Pastas 22/2010
Title:
Synaptic competition in structural plasticity and cognitive function
Publication year: 2013
URL:
Visitante: / http://rstb.royalsocietypublishing.org/content/369/1633/20130157.long
Abstract/Results: ABSTRACT:
Connections between neurons can undergo long-lasting changes in synaptic strength correlating with changes in structure. These events require the synthesis of new proteins, the availability of which can lead to cooperative and competitive interactions between synapses for the expression of plasticity. These processes can occur over limited spatial distances and temporal periods, defining dendritic regions over which activity may be integrated and could lead to the physical rewiring of synapses into functional groups. Such clustering of inputs may increase the computational power of neurons by allowing information to be combined in a greater than additive manner. The availability of new proteins may be a key modulatory step towards activity-dependent, long-term growth or elimination of spines necessary for remodelling of connections. Thus, the aberrant growth or shrinkage of dendritic spines could occur if protein levels are misregulated. Indeed, such perturbations can be seen in several mental retardation disorders, wherein either too much or too little protein translation exists, matching an observed increase or decrease in spine density, respectively. Cellular events which alter protein availability could relieve a constraint on synaptic competition and disturb synaptic clustering mechanisms. These changes may be detrimental to modifications in neural circuitry following activity.
Accessibility: Document exists in file
Language:
eng
Author:
Ramiro-Cortés, Y.. Hobbis, A.. Israely, I.
Document type:
Article
Number of reproductions:
1
Percentiles:
45.80|0.48
Reference:
Ramiro-Cortés, Y., Hobbis, A., & Israely, I. (2013). Synaptic competition in structural plasticity and cognitive function. Philosophical Transactions of the Royal Society B Biological Sciences, 369(1633): 20130157. https://doi.org/10.1098/rstb.2013.0157
Impact Factor: 6.314|2013
Times cited: 39|2026-02-06
Indexed document: Yes
Quartile: Q1
Keywords: Clustered plasticity / Competition / Dendritic spines / Mental retardation / Spine elimination / Structural plasticity

Synaptic competition in structural plasticity and cognitive function

Synaptic competition in structural plasticity and cognitive function
DocumentOxytocin and vasopressin modulation of prisoner’s dilemma strategies2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-292
Location: BF-GMS
Title:
292 - Oxytocin: On the psychophysiology of trust and cooperation
Duration: 2017-10 - 2023-11
Researcher(s):
Diana Prata, James Rilling, Manuel Lopes, Duarte Ferreira, Daniel Martins, Pedro Levy
Institution(s): FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências (Portugal); Emory University, Atlanta (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Prata, D.
Secondary author(s):
Rilling, J., Lopes, M., Ferreira, D. , Martins, D., Levy, P.
Number of reproductions:
1
Keywords:
Oxytocin / Mentalizing / Theory of mind / Dopamine / Psychophysiology

Reference code: PT/FB/BL-2016-292.03
Location: BF-GMS
Title:
Oxytocin and vasopressin modulation of prisoner’s dilemma strategies
Publication year: 2020
URL:
Visitante: / https://journals.sagepub.com/doi/abs/10.1177/0269881120913145?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=jopa
Abstract/Results: ABSTRACT:
BACKGROUND:
The neuropeptides oxytocin and vasopressin have been repeatedly implicated in social decision making by enhancing social salience and, generally, cooperation. The iterated and sequential version of the prisoner's dilemma (PD) game is a social dilemma paradigm eliciting strategies of cooperation versus competition.
AIMS:
We aimed to characterise the role of PD players' sex, game partner type (computer vs. human) and oxytocin or vasopressin inhalation on the player's strategy preference.
METHODS:
Participants (153 men; 151 women) were randomised to intranasal 24?IU oxytocin, 20?IU vasopressin or placebo, double-blind, and played the PD. We examined main and interactive effects of sex, drug and partner type on strategy preference.
RESULTS:
We found a pervasive preference for a tit-for-tat strategy (i.e. general sensitivity to the partner's choices) over unconditional cooperation, particularly when against a human rather than a computer partner. Oxytocin doubled this sensitivity in women (i.e. the preference for tit-for-tat over unconditional cooperation strategies) when playing against computers, which suggests a tendency to anthropomorphise them, and doubled women's unconditional cooperation preference when playing against humans. Vasopressin doubled sensitivity to the partner's previous choices (i.e. for tit-for-tat over unconditional cooperation) across sexes and partner types.
CONCLUSIONS:
These findings suggest that women may be more sensitive to oxytocin's social effects of anthropomorphism of non-humans and of unconditional cooperation with humans, which may be consistent with evolutionary pressures for maternal care, and that vasopressin, irrespective of sex and partner type, may be generally sensitising humans to others' behaviour.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Neto, M. L.
Secondary author(s):
Antunes, M., Lopes, M., Ferreira, D., Rilling, J., Prata, D.
Document type:
Article
Number of reproductions:
1
Percentiles:
58.55|0.67
Reference:
Neto, M. L., Antunes, M., Lopes, M., Ferreira, D., Rilling, J., & Prata, D. (2020). Oxytocin and vasopressin modulation of prisoner’s dilemma strategies. Journal of Psychopharmacology, 34(8), 891–900. https://doi.org/10.1177/0269881120913145
Impact Factor: 4.153|2020
Times cited: 13|2026-02-12
Indexed document: Yes
Quartile: Q2
Keywords: Neuropeptides / Cognitive empathy / Competition / Cooperation / Game theory / Mentalising / Prisoner’s dilemma / Theory of mind
DocumentIndividuals expend more effort to compete against robots than humans after observing competitive human–robot interactions2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-228
Location: BF-GMS
Title:
228 - Blurring the line between human and robot? Mapping and manipulating the socialness gradient in the brain
Duration: 2019-05 - 2021-09
Researcher(s):
Ruud Hortensius, Emily Cross
Institution(s): Centre for Social, Cognitive and Affective Neuroscience - cSCAN, Institute of Neuroscience and Psychology, University of Glasgow (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Hortensius, R.
Secondary author(s):
Cross, E.
Number of reproductions:
1
Keywords:
Attribution of socialness / Anthropomorphism / Dehumanisation / Psychophysiology

Reference code: PT/FB/BL-2018-228.06
Location: BF-GMS
Title:
Individuals expend more effort to compete against robots than humans after observing competitive human–robot interactions
Publication year: 2021
URL:
Visitante: / https://link.springer.com/chapter/10.1007%2F978-3-030-90525-5_60
Abstract/Results: In everyday life, we often observe and learn from interactions between other individuals—so-called third-party encounters. As robots are poised to become an increasingly familiar presence in our daily lives, third-party encounters between other people and robots might offer a valuable approach to influence people’s behaviors and attitudes towards robots. Here, we conducted an online experiment where participants (n = 48) watched videos of human—robot dyads interacting in a cooperative or competitive manner. Following this observation, we measured participants’ behavior and attitudes towards the human and robotic agents. First, participants played a game with the agents to measure whether their behavior was affected by their observed encounters. Second, participants’ attitudes toward the agents were measured before and after the game. We found that the third-party encounters influenced behavior during the game but not attitudes towards the observed agents. Participants showed more effort towards robots than towards humans, especially when the human and robot agents were framed as competitive in the observation phase. Our study suggests that people’s behaviors towards robots can be shaped by the mere observation of third-party encounters between robots and other people.
Accessibility: Document exists in file
Copyright/Reproduction:
by permission
Language:
eng
Author:
Timmerman, R.H.,
Secondary author(s):
Hsieh, T.-Y. , Henschel, A. , Hortensius, R. , Cross, E. S.
Document type:
Conference paper
Number of reproductions:
1
Percentiles:
50.43|0.31
Reference:
Timmerman, R. H., Hsieh T.-Y., Henschel A., Hortensius R., Cross E.S. (2021) Individuals expend more effort to compete against robots than humans after observing competitive human–robot interactions. In: Li H. et al. (eds) Social Robotics. ICSR 2021. Lecture Notes in Computer Science, vol 13086. Springer, Cham. https://doi.org/10.1007/978-3-030-90525-5_60
Times cited: 2|2026-02-13
Indexed document: Yes
Keywords: Human—robot interaction / Third-party encounters / Social robotics / Artificial agents / Social cognition / Cooperation / Competition

Individuals expend more effort to compete against robots than humans after observing competitive human–robot interactions

Individuals expend more effort to compete against robots than humans after observing competitive human–robot interactions
DocumentComputer anthropomorphisation in a socio-economic dilemma2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-292
Location: BF-GMS
Title:
292 - Oxytocin: On the psychophysiology of trust and cooperation
Duration: 2017-10 - 2023-11
Researcher(s):
Diana Prata, James Rilling, Manuel Lopes, Duarte Ferreira, Daniel Martins, Pedro Levy
Institution(s): FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências (Portugal); Emory University, Atlanta (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Prata, D.
Secondary author(s):
Rilling, J., Lopes, M., Ferreira, D. , Martins, D., Levy, P.
Number of reproductions:
1
Keywords:
Oxytocin / Mentalizing / Theory of mind / Dopamine / Psychophysiology

Reference code: PT/FB/BL-2016-292.15
Location: BF-GMS
Title:
Computer anthropomorphisation in a socio-economic dilemma
Publication year: 2024
URL:
Visitante: / https://link.springer.com/article/10.3758/s13428-023-02071-y#citeas
Abstract/Results: ABSTRACT:
In the study of human behaviour, non-social targets are often used as a control for human-to-human interactions. However, the concept of anthropomorphisation suggests that human-like qualities can be attributed to non-human objects. This can prove problematic in psychological experiments, as computers are often used as non-social targets. Here, we assessed the degree of computer anthropomorphisation in a sequential and iterated prisoner’s dilemma. Participants (N = 41) faced three opponents in the prisoner’s dilemma paradigm—a human, a computer, and a roulette—all represented by images presented at the commencement of each round. Cooperation choice frequencies and transition probabilities were estimated within subjects, in rounds against each opponent. We found that participants anthropomorphised the computer opponent to a high degree, while the same was not found for the roulette (i.e. no cooperation choice difference vs human opponents; p = .99). The difference in participants’ behaviour towards the computer vs the roulette was further potentiated by the precedent roulette round, in terms of both cooperation choice (61%, p = .007) and cooperation probability after reciprocated defection (79%, p = .007). This suggests that there could be a considerable anthropomorphisation bias towards computer opponents in social games, even for those without a human-like appearance. Conversely, a roulette may be a preferable non-social control when the opponent’s abilities are not explicit or familiar.
Accessibility: Document exists in file
Language:
eng
Author:
Cogoni, C.
Secondary author(s):
Fiuza, A., Hassanein, L., Antunes, M., Prata, D.
Document type:
Article
Number of reproductions:
1
Percentiles:
39.68|0.50
Reference:
Cogoni, C., Fiuza, A., Hassanein, L., Antunes, M., & Prata, D. (2024). Computer anthropomorphisation in a socio-economic dilemma. Behavior Research Methods, 56(2), 667–679. https://doi.org/10.3758/s13428-023-02071-y
Impact Factor: 3.9|2024
Times cited: 3|2026-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Prisoner’s dilemma / Social dilemma / Anthropomorphisation / Roulette / Computer / Cooperation / Competition / Social behaviour

Computer anthropomorphisation in a socio-economic dilemma

Computer anthropomorphisation in a socio-economic dilemma