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File159 - Unraveling the neural mechanisms of human memory decisions with magnetoencephalography2017-052022-11

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-159
Location: BF-GMS
Title:
159 - Unraveling the neural mechanisms of human memory decisions with magnetoencephalography
Duration: 2017-05 - 2022-11
Researcher(s):
Carlo Sestieri, Stefania Della Penna
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Sestieri, C.
Secondary author(s):
Della Penna, S.
Number of reproductions:
1
Keywords:
Magnetoencephalography / Episodic memory / Decision evidence / Cortical dynamics / Psychophysiology

DocumentFinal report - Unraveling the neural mechanisms of human memory decisions with magnetoencephalography2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-159
Location: BF-GMS
Title:
159 - Unraveling the neural mechanisms of human memory decisions with magnetoencephalography
Duration: 2017-05 - 2022-11
Researcher(s):
Carlo Sestieri, Stefania Della Penna
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Sestieri, C.
Secondary author(s):
Della Penna, S.
Number of reproductions:
1
Keywords:
Magnetoencephalography / Episodic memory / Decision evidence / Cortical dynamics / Psychophysiology

Reference code: PT/FB/BL-2016-159.01
Location: BF-GMS
Title:
Final report - Unraveling the neural mechanisms of human memory decisions with magnetoencephalography
Publication year: 2019
Abstract/Results:
ABSTRACT:
Previous fMRI studies suggest that the retrieval-related activity observed in the left lateral intraparietal sulcus (IPS) might reflect a neural accumulator of evidence for memory-based decisions. In the present MEG study, we examined the dynamics of oscillatory activity in a set of previously defined cortical regions to identify potential markers of mnemonic evidence accumulation. Healthy human subjects (N=22) participated in a memory retrieval experiment that employed the manipulation of evidence for old/new decisions. Magnetic activity was estimated in six regions of interest (IPS, prefrontal cortex, caudate nuclei, bilaterally) derived from our previous fMRI study. We estimated several properties (peak amplitude, peak latency, duration, rising and falling speed) of event-related synchronization/desynchronization (ERS/ERD) in six oscillatory bands (d, ?, a, low-ß, low-?, high-?). A 3-way repeated measures ANOVA with region, memory status and evidence as factors was conducted on each property/band. The analysis revealed a significant main effect of memory status on the duration [p=0.044] and peak amplitude [p=0.013] of the alpha ERD. Since we observed a main effect of the region on several properties of the alpha ERD, we next directly tested whether the amount of decision evidence affected the oscillatory dynamics in left IPS. A main effect of evidence was observed on alpha ERD duration [p=0.042] and, crucially, on the ERD falling speed [p=0.050], meaning that the higher the evidence, the faster the ERD reached its peak. These findings are highly consistent with a mnemonic accumulator, as hypothesized by decision-making accounts of parietal activity during memory retrieval.
Accessibility: Document exists in file
Language:
eng
Author:
Sestieri, C.
Secondary author(s):
Della Penna, S.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Magnetoencephalography / Episodic memory / Decision evidence / Cortical dynamics

Final report - Unraveling the neural mechanisms of human memory decisions with magnetoencephalography

Final report - Unraveling the neural mechanisms of human memory decisions with magnetoencephalography