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DocumentHypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-036
Location: Arquivo PCA - Pasta 18/2006
Title:
036 - The psychophysiology of neurological abnormalities in first episode psychosis and in healthy individuals - A study using multimodal brain imaging
Duration: 2007-03 - 2010-09
Researcher(s):
Paola Dazzan, Philip McGuire, Carmine Pariante, Marta Di Forti, Julia Lappin, Valeria Mondelli
Institution(s): Division of Psychological Medicine, Institute of Psychiatry, London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
1 Article
Language: eng
Author:
Dazzan, P.
Secondary author(s):
McGuire, P., Pariante, C., Di Forti, M., Lappin, J., Mondelli, V.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders / Body structure and function / Audition / Movement / Vision

Reference code: PT/FB/BL-2006-036.07
Location: Arquivo PCA - Pasta 18/2006
Title:
Hypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis
Publication year: 2011
URL:
http://www.psyneuen-journal.com/article/PIIS030645301100268X/abstract?rss=yes
Abstract/Results: ABSTRACT:
BACKGROUND:
Abnormalities in hypothalamic-pituitary-adrenal (HPA) axis activity have been reported in patients with psychosis, but it is still unclear how these are related to the clinical symptomatology. Inconsistent findings have emerged from previous studies on the association between cortisol levels and clinical symptoms. Methodological and/or clinical factors, such as patients' diagnosis or illness phase, might partially account for these inconsistencies. The aim of this study was to investigate the association between HPA axis activity and clinical symptoms in first-episode psychosis, taking into account diagnosis and illness phase.
METHOD:
Saliva samples were collected in 55 subjects with first-episode psychosis to assess the Cortisol Awakening Response (CAR) and diurnal cortisol levels (AUC-DAY). Severity of symptoms was assessed with the Positive and Negative Syndrome Scale (PANSS). Scores for subscales and symptom dimensions were used as predictors in multivariate analyses in different diagnostic subgroups and in clinically remitted patients. In addition, a systematic review of the literature on this topic was conducted.
RESULTS:
In subjects with schizophrenia (n=36), the CAR was predicted by the severity of positive symptoms (beta=0.47, p=0.04); in subjects with depressive psychoses (n=8) the CAR was predicted by excitement (beta=0.58, p=0.005), disorganization (beta=0.39, p=0.007) and depressive symptoms (beta=0.32, p=0.005). In patients with bipolar psychoses (n=11) AUC-DAY was predicted negatively by disorganization (beta=-2.82, p=0.009) and positively by excitement (beta=2.06, p=0.009) and positive symptoms (beta=1.28, p=0.02). In the sample in clinical remission (n=9), the CAR was associated with the severity of positive symptoms (beta=1.34, p=0.009) and, negatively, with excitement (beta=-1.05, p=0.04). The systematic review (on a total of 28 papers, including n=1022 patients), found that in patients with psychosis cortisol levels have been associated with the severity of multiple symptom dimensions.
CONCLUSIONS:
HPA axis activity is associated with the severity of multiple types of symptoms in first-episode psychosis. Patients' diagnosis and clinical phase partially influence these associations.
Accessibility: Document does not exist in file
Language:
eng
Author:
Belvederi Murri, M.
Secondary author(s):
Pariante, C., Dazzan, P., Hepgul, N., Papadopoulos, A., Zunszain, P., Di Forti, M., Murray, R., Mondelli, V.
Document type:
Article
Number of reproductions:
1
Reference:
Belvederi Murri, M., Pariante, C., Dazzan, P., Hepgul, N., Papadopoulos, A., Zunszain, P., Di Forti, M., Murray, R., & Mondelli, V. (2011). Hypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis. Psychoneuroendocrinology, 37(5), 629-644. https://doi.org/10.1016/j.psyneuen.2011.08.013
2-year Impact Factor: 5.809|2011
Times cited: 68|2024-02-01
Indexed document: Yes
Quartile: Q1
Keywords: Cortisol / Cortisol awakening response / Hypothalamic-pituitary-adrenal axis / Symptoms / Psychosis / Schizophrenia / Bipolar / Depression / Diagnosis / Remission / Neuroendocrinology
DocumentFinal report - Percepção Extra-sensorial: um estudo acerca da possibilidade de visão heteroscópica2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-179
Location: Arquivo PCA - Pasta 21/2008
Title:
179 - Percepção Extra-sensorial: um estudo acerca da possibilidade de visão heteroscópica
Duration: 2009-01 - 2010/04
Researcher(s):
Álvaro Luiz Tronconi, Moema da Silva Borges, Joel Paulo Russomano Veiga, Cleunice de Arruda Castro, Eloina Terezinha Domanski, Walkyria Eyre
Institution(s): HUB – Hospital Universitário de Brasília e NEFP – Núcleo de Estudos dos Fenômenos Paranormais, Brasília (Brazil)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: por / eng
Author:
Tronconi, A.
Secondary author(s):
Borges, M., Veiga, J., Castro, C., Domanski, E., Eyre, W.
Number of reproductions:
2
Keywords:
Parapsychology / Extrasensory perception (ESP)

Reference code: PT/FB/BL-2008-179.01
Location: Arquivo PCA - Pasta 21/2008
Title:
Final report - Percepção Extra-sensorial: um estudo acerca da possibilidade de visão heteroscópica
Publication year: 2010
Abstract/Results:
RESULTS:
The Mann-Whitney test, applied to the data as presented on the Methodology, evidenced some peculiarities, in which the number of results FP becomes statistically significant, expressing that the sensitive seeks to attain a higher number of hits by guessing a high number of suggestions. On the other hand, his remote-viewing results, are slightly better than the presential ones which may suggest that there was no cold reading.
Greater difference between the presential and remote data of the sensitive 123 which could suggest cold reading. The same observation could be made for the results of the sensitive 001, but for all this data the statistic difference among them was not significant. Other important result evidence that the fact of believing or not in HV does not alter the performance of the sensitives. Other data showed evidence of a slight improvement on the performance of the sensitive after his 3rd data collection, probably optimizing it. All the sensitives studied presented more hits on the SD - Sindromic Diagnosis, A possible interpretation of these results would be that the sensitives were not decoding correctly the accessed information during the process of their extra-sensorial perceptions. The Kappa Indicator test shows that the hits and errors attained by two or more sensitives on the same patients have no correlation between them.
It is important to say that the sensitives 800 and 900 collected their data simultaneously, on the same room, evidencing that the fact of diagnosing the same patient simultaneously had no effect on their performance.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
por
Author:
Tronconi, A.
Secondary author(s):
Borges, M., Veiga, J., Castro, C., Domanski, E., Eyre, W.
Document type:
Final report
Number of reproductions:
2
Indexed document:
No
Keywords: Parapsychology / Extrasensory perception (ESP) / Diagnosis

Final report - Percepção Extra-sensorial: um estudo acerca da possibilidade de visão heteroscópica

Final report - Percepção Extra-sensorial: um estudo acerca da possibilidade de visão heteroscópica
DocumentDispepsia: Causas, sintomas e diagnóstico

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/024
Title: Dispepsia: Causas, sintomas e diagnóstico
Número de inventário: M-0025
Local: Porto
Publisher: Laboratórios Bial
Date: 1991
Pag., vols.: 253 p.
Illustration: il.
Dimension/support: 24 cm
Accessibility: Document exists in archive
Copyright/Reproduction:
By permission
Language:
por
Notes:
Prémio Bial de Medicina Clínica 1990 - Menção Honrosa
Edition: 1ª ed.
Collection: (Bial ; 9)
Author: Cabral, J.
Document type:
Book
Keywords:
Dyspepsia / Etiology / Symptoms / Diagnosis
DocumentDoença de Machado-Joseph: Estudo clínico, patológico e epidemiológico de uma doença neurológica de origem Portuguesa

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/025
Title: Doença de Machado-Joseph: Estudo clínico, patológico e epidemiológico de uma doença neurológica de origem Portuguesa
Número de inventário: M-0026
Local: Porto
Publisher: Laboratórios Bial
Date: 1994
Pag., vols.: 263
Illustration: il.
Dimension/support: 24 cm
Accessibility: Document exists in archive
Copyright/Reproduction:
By permission
Language:
por
Notes:
Grande Prémio Bial de Medicina 1992 - 1º classificado
Edition: 1ª ed.
Collection: (Bial ; 10)
Author: Coutinho, P.
Document type:
Book
Keywords:
Machado-Joseph disease / Symptoms / Diagnosis / Classification / Epidemiology / Treatment / Prevention
DocumentDoenças do comportamento alimentar: Manual para o clínico geral

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/037
Title: Doenças do comportamento alimentar: Manual para o clínico geral
Número de inventário: M-0038
Local: Porto
Publisher: Laboratórios Bial
Date: 1999
Pag., vols.: 138 p.
Illustration: il.
Dimension/support: 24 cm
Accessibility: Document exists in archive
Copyright/Reproduction:
By permission
Language:
por
Notes:
Prémio Bial de Medicina Clínica 1998
Edition: 1ª ed.
Collection: (Bial ; 22)
Author: Sampaio, D.
Secondary author(s):
Bouça, D., Carmo, I., Jorge, Z.
Document type:
Book
Keywords:
Eating disorders / Epidemiology / Etiology / Diagnosis / Clinical practice / Treatment / Disease progression
DocumentThe long fuse: Silent strokes and insidious Alzheimer disease

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/055
Title: The long fuse: Silent strokes and insidious Alzheimer disease
Número de inventário: M-0056
Local: Porto
Publisher: Laboratórios Bial
Date: 2010
Pag., vols.: 71 p.
Illustration: graphs
Dimension/support: 24 cm
Accessibility: Document exists in archive
Copyright/Reproduction:
By permission
Language:
eng
Notes:
Grande Prémio Bial de Medicina 2010
Edition: 1ª ed.
Collection: (Bial ; 41)
Author: Hachinski, V.
Document type:
Book
Keywords:
Alzheimer's disease / Stroke patients / Prevention / Diagnosis / Subclinical / Risk factors
DocumentDiscounting trait inferences: Are mental health disorders alternative behavioral explanations?2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-085
Location: BF-GMS
Title:
085 - The Clinical Gut: Examining the cognitive processes and neural underpinnings of judgments, feelings of rightness and its impact on information seeking
Duration: 2015-05 - 2021-02
Researcher(s):
Ana Sofia Bilreiro Jacinto Braga, Anne Krendl, Cara Charissa Lewis, Cilia Witteman, Elizabeth Collins, João Braga
Institution(s): Centro de Investigação e Intervenção Social (CIS-IUL), ISCTE - Instituto Universitário de Lisboa (Portugal); Department of Psychological and Brain Sciences - Indiana University Bloomington (USA)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Author: Jacinto, S.
Secondary author(s):
Krendl, A., Lewis, C., Wittmann, C., Ferreira, M.
Number of reproductions:
1
Keywords:
Feelings of Rightness / Information Seeking / Clinical Judgment / Hypotheses Testing / Psychophysiology

Reference code: PT/FB/BL-2014-085.04
Location: BF-GMS
Title:
Discounting trait inferences: Are mental health disorders alternative behavioral explanations?
Publication year: 2016
URL:
http://www.google.pt/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&cad=rja&uact=8&ved=0ahUKEwip44ij5_XNAhXIVRQKHTtyAPUQFgggMAE&url=http%3A%2F%2Fwww.appe.pt%2Fencontro%2Ffiles%2FProgramaAPPE-2016-Posters.pdf&usg=AFQjCNET5UiOiXV3UykfdLXKhrCd-h_ecg&sig2=XFyetJxSqZgi6cEeH-Vn6A&bvm=bv.127178174,d.d24
Abstract/Results: ABSTRACT:
Behaviors representative of a mental health disorder should be categorized as symptoms and not as dispositional traits (DSM-5). We tested whether disorder diagnoses would thus lead to discount trait inferences as situational explanations for the behaviors (e.g., Gilbert et al., 1988). Psychology students were presented with brief trait-implying behavioural descriptions (of different targets), each one followed by one of three continuations: neutral, situational and disorder-diagnosis. Participants then rated each target on a list of traits (including the implied traits). Compared to the neutral condition, the situational but not the disorder-diagnosis condition led to a decreased in the implied-trait inferences. This suggests that, mental health disorders are not used to discount trait inferences from behavior.
Accessibility: Document does not exist in file
Language:
eng
Author:
Jacinto, S.
Secondary author(s):
Ferreira, M., Ferreira, M.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Jacinto, S., Ferreira, M., & Ferreira, M. (2016, April). Discounting trait inferences: Are mental health disorders alternative behavioral explanations? Paper presented at the 11º Encontro Nacional da Associação Portuguesa de Psicologia Experimental, Lisboa. Portugal.
Indexed document: No
Keywords: Mental health disorders / Diagnosis

Discounting trait inferences: Are mental health disorders alternative behavioral explanations?

Discounting trait inferences: Are mental health disorders alternative behavioral explanations?
DocumentDiagnostic, pronostic et traitements des troubles de la conscience2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-18
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Diagnostic, pronostic et traitements des troubles de la conscience
Publication year: 2018
URL:
https://www.sciencedirect.com/science/article/pii/S1627483017300661
Abstract/Results: ABSTRACT:
Advances in medicine and intensive care have led to an increase in the number of patients surviving a severe brain injury. Although some patients recover quickly, others remain in a state of altered consciousness. These patients can progress from a coma to a vegetative state or unresponsive wakefulness syndrome (VS/UWS) and later to a minimally conscious state (MCS). In this review, we first describe the different behavioral and neuroimaging methods used in the diagnosis of patients in an altered state of consciousness. We then describe the factors that can influence the prognosis and recovery of these patients, as well as the treatment and therapeutic management that can be proposed in order to improve their state of consciousness. Finally, we conclude this review by highlighting ethical considerations and end-of-life issues.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
french
Author:
Cassol, H.
Secondary author(s):
Aubinet, C., Thibaut, A., Wannez, S., Martial, C., Martens, G., Laureys, S.
Document type:
Article
Number of reproductions:
3
Reference:
Cassol, H., Aubinet, C., Thibaut, A., Wannez, S., Martial, C., Martens, G., & Laureys, S. (2018). Diagnosis, prognosis and treatment in disorders of consciousness [Diagnostic, pronostic et traitements des troubles de la conscience]. NPG Neurologie - Psychiatrie - Geriatrie, 18(103), 38-46.
2-year Impact Factor: N/A
Times cited: N/A
Indexed document: Yes
Quartile: N/A
Keywords: Consciousness / Brain injury / Diagnosis / Prognosis / Treatment / Altered states of consciousness / Coma / Vegetative state / Unresponsive wakefulness syndrome / Minimally conscious state / Locked-in syndrome / Neuroimaging / Positron emission tomography / Coma Recovery Scale-Revised / Magnetic resonance / Electroencephalography / Transcranial magnetic stimulation
DocumentRobust EEG-based cross-site and cross-protocol classification of states of consciousness2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-34
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Robust EEG-based cross-site and cross-protocol classification of states of consciousness
Publication year: 2018
URL:
https://academic.oup.com/brain/article-abstract/141/11/3179/5114404?redirectedFrom=fulltext
Abstract/Results: ABSTRACT
Determining the state of consciousness in patients with disorders of consciousness is a challenging practical and theoretical problem. Recent findings suggest that multiple markers of brain activity extracted from the EEG may index the state of consciousness in the human brain. Furthermore, machine learning has been found to optimize their capacity to discriminate different states of consciousness in clinical practice. However, it is unknown how dependable these EEG markers are in the face of signal variability because of different EEG configurations, EEG protocols and subpopulations from different centres encountered in practice. In this study we analysed 327 recordings of patients with disorders of consciousness (148 unresponsive wakefulness syndrome and 179 minimally conscious state) and 66 healthy controls obtained in two independent research centres (Paris Pitié-Salpêtrière and Liège). We first show that a non-parametric classifier based on ensembles of decision trees provides robust out-of-sample performance on unseen data with a predictive area under the curve (AUC) of ~0.77 that was only marginally affected when using alternative EEG configurations (different numbers and positions of sensors, numbers of epochs, average AUC = 0.750 ± 0.014). In a second step, we observed that classifiers based on multiple as well as single EEG features generalize to recordings obtained from different patient cohorts, EEG protocols and different centres. However, the multivariate model always performed best with a predictive AUC of 0.73 for generalization from Paris 1 to Paris 2 datasets, and an AUC of 0.78 from Paris to Liège datasets. Using simulations, we subsequently demonstrate that multivariate pattern classification has a decisive performance advantage over univariate classification as the stability of EEG features decreases, as different EEG configurations are used for feature-extraction or as noise is added. Moreover, we show that the generalization performance from Paris to Liège remains stable even if up to 20% of the diagnostic labels are randomly flipped. Finally, consistent with recent literature, analysis of the learned decision rules of our classifier suggested that markers related to dynamic fluctuations in theta and alpha frequency bands carried independent information and were most influential. Our findings demonstrate that EEG markers of consciousness can be reliably, economically and automatically identified with machine learning in various clinical and acquisition contexts.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Engemann, D. A.
Secondary author(s):
Raimondo, F., King, J. R., Rohaut, B., Louppe, G., Faugeras, F., Annen, J., Cassol, H., Gosseries, O., Fernandez-Slezak, D., Laureys, S., Naccache, L., Dehaene, S., Sitt, J. D.
Document type:
Article
Number of reproductions:
3
Percentiles:
4
Reference:
Engemann, D. A., Raimondo, F., King, J. R., Rohaut, B., Louppe, G., Faugeras, F., ... Sitt, J. D. (2018). Robust EEG-based cross-site and cross-protocol classification of states of consciousness. Brain, 141(11), 3179-3192. https://doi.org/10.1093/brain/awy251
2-year Impact Factor: 11.814|2018
Times cited: 154|2024-02-09
Indexed document: Yes
Quartile: Q1
Keywords: Electroencephalography / Disorders of consciousness / Biomarker / Machine learning / Diagnosis
DocumentAuditory localization should be considered as a sign of minimally conscious state based on multimodal findings2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-66
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Auditory localization should be considered as a sign of minimally conscious state based on multimodal findings
Publication year: 2020
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784043/
Abstract/Results: ABSTRACT:
Auditory localization (i.e. turning the head and/or the eyes towards an auditory stimulus) is often part of the clinical evaluation of patients recovering from coma. The objective of this study is to determine whether auditory localization could be considered as a new sign of minimally conscious state, using a multimodal approach. The presence of auditory localization and the clinical outcome at 2 years of follow-up were evaluated in 186 patients with severe brain injury, including 64 with unresponsive wakefulness syndrome, 28 in minimally conscious state minus, 71 in minimally conscious state plus and 23 who emerged from the minimally conscious state. Brain metabolism, functional connectivity and graph theory measures were investigated by means of F-18-fluorodeoxyglucose positron emission tomography, functional MRI and high-density electroencephalography in two subgroups of unresponsive patients, with and without auditory localization. These two subgroups were also compared to a subgroup of patients in minimally conscious state minus. Auditory localization was observed in 13% of unresponsive patients, 46% of patients in minimally conscious state minus, 62% of patients in minimally conscious state plus and 78% of patients who emerged from the minimally conscious state. The probability to observe an auditory localization increased along with the level of consciousness, and the presence of auditory localization could predict the level of consciousness. Patients with auditory localization had higher survival rates (at 2-year follow-up) than those without localization. Differences in brain function were found between unresponsive patients with and without auditory localization. Higher connectivity in unresponsive patients with auditory localization was measured between the fronto-parietal network and secondary visual areas, and in the alpha band electroencephalography network. Moreover, patients in minimally conscious state minus significantly differed from unresponsive patients without auditory localization in terms of brain metabolism and alpha network centrality, whereas no difference was found with unresponsive patients who presented auditory localization. Our multimodal findings suggest differences in brain function between unresponsive patients with and without auditory localization, which support our hypothesis that auditory localization should be considered as a new sign of minimally conscious state. Unresponsive patients showing auditory localization should therefore no longer be considered unresponsive but minimally conscious. This would have crucial consequences on these patients' lives as it would directly impact the therapeutic orientation or end-of-life decisions usually taken based on the diagnosis.
Accessibility: Document exists in file
Language:
eng
Author:
Carrière, M.
Secondary author(s):
Cassol, H., Aubinet, C., Panda, R., Thibaut, A., Larroque, S. K., Simon, J., Martial, C., Bahri, M. A., Chatelle, C., Martens, G., Chennu, S., Laureys, S., Gosseries, O.
Document type:
Article
Number of reproductions:
3
Reference:
Carrière, M., Cassol, H., Aubinet, C., Panda, R., Thibaut, A., Larroque, S. K., Simon, J., Martial, C., Bahri, M. A., Chatelle, C., Martens, G., Chennu, S., Laureys, S., & Gosseries, O. (2020). Auditory localization should be considered as a sign of minimally conscious state based on multimodal findings. Brain Communications, 2(2): fcaa195. https://doi.org/10.1093/braincomms/fcaa195
2-year Impact Factor: 4.8|2022
Impact factor notes: Impact factor only available since 2022
Times cited: 10|2024-02-13
Indexed document: Yes
Quartile: Q3
Keywords: Disorders of consciousness / Auditory localization / Diagnosis / Brain imaging / Electroencephalography

Auditory localization should be considered as a sign of minimally conscious state based on multimodal findings

Auditory localization should be considered as a sign of minimally conscious state based on multimodal findings
DocumentDecreased evoked slow-activity after tDCS in disorders of consciousness2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-71
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Decreased evoked slow-activity after tDCS in disorders of consciousness
Publication year: 2020
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546425/
Abstract/Results: ABSTRACT:
Due to life-saving medical advances, the diagnosis and treatment of disorders of consciousness (DOC) has become a more commonly occurring clinical issue. One recently developed intervention option has been non-invasive transcranial direct current stimulation. This dichotomy of patient responders may be better understood by investigating the mechanism behind the transcranial direct current stimulation (tDCS) intervention. The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has been an important diagnostic tool in DOC patients. We therefore examined the neural response using TMS-EEG both before and after tDCS in seven DOC patients (four diagnosed as in a minimally conscious state and three with unresponsive wakefulness syndrome). tDCS was applied over the dorsolateral prefrontal cortex, while TMS pulses were applied to the premotor cortex. None of the seven patients showed relevant behavioral change after tDCS. We did, however, find that the overall evoked slow activity was reduced following tDCS intervention. We also found a positive correlation between the strength of the slow activity and the amount of high-frequency suppression. However, there was no significant pre-post tDCS difference in high frequencies. In the resting-state EEG, we observed that both the incidence of slow waves and the positive slope of the wave were affected by tDCS. Taken together, these results suggest that the tDCS intervention can reduce the slow-wave activity component of bistability, but this may not directly affect high-frequency activity. We hypothesize that while reduced slow activity may be necessary for the recovery of neural function, especially consciousness, this alone is insufficient.
Accessibility: Document exists in file
Language:
eng
Author:
Mensen, A.
Secondary author(s):
Bodart, O., Thibaut, A., Wannez, S., Annen, J., Laureys, S., Gosseries, O.
Document type:
Article
Number of reproductions:
3
Percentiles:
6
Reference:
Mensen, A., Bodart, O., Thibaut, A., Wannez, S., Annen, J., Laureys, S., & Gosseries, O. (2020). Decreased evoked slow-activity after tDCS in disorders of consciousness. Frontiers in System Neuroscience, 14: 62. https://doi.org/10.3389/fnsys.2020.00062
2-year Impact Factor: 3.289|2020
Times cited: 7|2024-02-13
Indexed document: Yes
Quartile: Q3
Keywords: Disorders of consciousness / Transcranial direct current stimulation / Transcranial magnetic stimulation / Electroencephalography / Bistability / Slow activity / Diagnosis / Treatment

Decreased evoked slow-activity after tDCS in disorders of consciousness

Decreased evoked slow-activity after tDCS in disorders of consciousness
DocumentUpdate on neuroimaging in disorders of consciousness2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-98
Location: BF-GMS
Title:
Update on neuroimaging in disorders of consciousness
Publication year: 2021
URL:
https://journals.lww.com/co-neurology/Abstract/2021/08000/Update_on_neuroimaging_in_disorders_of.4.aspx
Abstract/Results: ABSTRACT:
Purpose of review:
Neuroimaging has acquired a prominent place in the assessment of disorders of consciousness (DoC). Rapidly evolving technologies combined with state-of-the-art data analyses open new horizons to probe brain activity, but selecting appropriate imaging modalities from the plethora of available techniques can be challenging for clinicians. This update reviews selected advances in neuroimaging that demonstrate clinical relevance and translational potential in the assessment of severely brain-injured patients with DoC.
Recent findings:
Magnetic resonance imaging and high-density electroencephalography provide measurements of brain connectivity between functional networks, assessments of language function, detection of covert consciousness, and prognostic markers of recovery. Positron emission tomography can identify patients with preserved brain metabolism despite clinical unresponsiveness and can measure glucose consumption rates in targeted brain regions. Transcranial magnetic stimulation and near-infrared spectroscopy are noninvasive and practical tools with promising clinical applications.
Summary:
Each neuroimaging technique conveys advantages and pitfalls to assess consciousness. We recommend a multimodal approach in which complementary techniques provide diagnostic and prognostic information about brain function. Patients demonstrating neuroimaging evidence of covert consciousness may benefit from early adapted rehabilitation. Translating methodological advances to clinical care will require the implementation of recently published international guidelines and the integration of neuroimaging techniques into patient-centered decision-making algorithms.
Accessibility: Document does not exist in file
Language:
eng
Author:
Sanz, L.
Secondary author(s):
Thibaut, A., Edlow, B. L., Laureys, S., Gosseries, O.
Document type:
Article
Number of reproductions:
3
Percentiles:
4
Reference:
Sanz, L., Thibaut, A., Edlow, B. L., Laureys, S., & Gosseries, O. (2021). Update on neuroimaging in disorders of consciousness. Current Opinion in Neurology, 34(4), 488-496. https://doi.org/10.1097/WCO.0000000000000951
2-year Impact Factor: 5.710|2020
Impact factor notes: Impact factor not available yet for 2021
Times cited: 28|2024-02-14
Indexed document: Yes
Quartile: Q1
Keywords: Coma / Diagnosis / Disorders of consciousness / Neuroimaging / Prognosis
DocumentValidation of the simplified evaluation of consciousness disorders (SECONDs) scale in Mandarin2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-117
Location: BF-GMS
Title:
Validation of the simplified evaluation of consciousness disorders (SECONDs) scale in Mandarin
Publication year: 2023
URL:
https://www.sciencedirect.com/science/article/pii/S1877065723000350?via%3Dihub
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Wang, A.
Secondary author(s):
Sun, L., Cheng, L., Hu, N., Sanz, L. R. D., Thibaut, A., Gosseries, O., Martial, C., Di, H.
Document type:
Letter
Number of reproductions:
3
Percentiles:
5
Reference:
Wang, A., Sun, L., Cheng, L., Hu, N., Chen, Y., Sanz, L. R. D., Thibaut, A., Gosseries, O., Martial, C., & Di, H. (2023). Validation of the simplified evaluation of consciousness disorders (SECONDs) scale in Mandarin. Annals of Physical and Rehabilitation Medicine, 66(7), 101764. https://doi.org/10.1016/j.rehab.2023.101764
2-year Impact Factor: 3.9|2023
Times cited: 1|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Behavioral scale / Coma / Diagnosis / Disorder of consciousness / Rehabilitation
DocumentExploring the significance of cognitive motor dissociation on patient outcome in acute disorders of consciousness2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-138
Location: BF-GMS
Title:
Exploring the significance of cognitive motor dissociation on patient outcome in acute disorders of consciousness
Publication year: 2024
URL:
https://doi.org/10.1055/s-0044-1785507
Abstract/Results: ABSTRACT:
Cognitive motor dissociation (CMD) is characterized by a dissociation between volitional brain responses and motor control, detectable only through techniques such as electroencephalography (EEG) and functional magnetic resonance imaging. Hence, it has recently emerged as a major challenge in the assessment of patients with disorders of consciousness. Specifically, this review focuses on the prognostic implications of CMD detection during the acute stage of brain injury. CMD patients were identified in each diagnostic category (coma, unresponsive wakefulness syndrome/vegetative state, minimally conscious state minus) with a relatively similar prevalence of around 20%. Current knowledge tends to indicate that the diagnosis of CMD in the acute phase often predicts a more favorable clinical outcome compared with other unresponsive non-CMD patients. Nevertheless, the review underscores the limited research in this domain, probably at least partially explained by its nascent nature and the lack of uniformity in the nomenclature for CMD-related disorders, hindering the impact of the literature in the field.
Accessibility: Document does not exist in file
Language:
eng
Author:
Lejeune, N.
Secondary author(s):
Fritz, P., Cardone, P., Szymkowicz, E., Vitello, M. M., Martial, C., Thibaut, A., Gosseries, O.
Document type:
Article
Number of reproductions:
3
Reference:
Lejeune, N., Fritz, P., Cardone, P., Szymkowicz, E., Vitello, M. M., Martial, C., Thibaut, A., & Gosseries, O. (2024). Exploring the significance of cognitive motor dissociation on patient outcome in acute disorders of consciousness. Seminars in Neurology, 44(3), 271–280. https://doi.org/10.1055/s-0044-1785507
2-year Impact Factor: O.63|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2024-10-16
Indexed document: Yes
Quartile: Q3
Keywords: Coma / Consciousness / Diagnosis / Prognosis / Outcome / Brain imaging / Cognitive motor dissociation