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DocumentSomatosensory pain is not reliably modulated by weak acoustic stimuli2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-186
Location: Arquivo PCA - Pasta 12/2010
Title:
186 - Brain mechanisms of placebo analgesia
Duration: 2011-03 - 2014-01
Researcher(s):
Magne Arve Flaten, Per M. Aslaksen, Torgil R. Vangberg, Odd Petter Eldevik, Jan Bergdahl, Sara Vambheim, Just C. Thoner
Institution(s): University of Tromsø and University Hospital of North Norway, Tromso (Norway)
Contents: Contents:
Bursary agreement
Application form + 12 articles (previous project team publications)
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Flaten, M.
Secondary author(s):
Aslaksen, P., Vangberg, T., Eldevik, O., Bergdahl, J., Vambheim, S., Thoner, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Emotion / Brain structure and function

Reference code: PT/FB/BL-2010-186.17
Location: Arquivo PCA - Pasta 10/2010
Title:
Somatosensory pain is not reliably modulated by weak acoustic stimuli
Publication year: 2016
URL:
http://www.sciencedirect.com/science/article/pii/S0167876015300568
Abstract/Results: ABSTRACT:
Background
Pain induced by electrical stimuli has been found in previous research to be reduced by brief, weak electrical pulses, termed prepulses, presented 40 to 60 ms prior to the painful electrical stimulus.
Methods
The present experiment investigated the generality of this effect by presenting weak acoustic stimuli simultaneously with, or 80 or 1000 ms prior to, painful electric shocks. In the second half of the experimental session, each participant (N = 119) was told that the acoustic stimuli would either increase or decrease the pain induced by the electric shock, to investigate automatic and controlled cognitive processes in the modulation of pain.
Results
Acoustic stimuli presented simultaneously with painful stimulation increased pain slightly (4 mm on a 100 mm scale). Acoustic stimuli presented 80 and 1000 ms prior to painful stimuli had no effect on pain. Information that acoustic stimuli would increase pain did so in females, but only when the acoustic stimulus was presented 80 ms prior to the painful stimulus.
Conclusions
The effect of the acoustic stimuli and of information was weak. Failure to replicate previous findings of decreased pain by weak prepulses was most likely due to the sensory modality of the prepulse stimuli. It is recommended that further studies of pain modulation by brief stimulation use electrical and not acoustic prepulse stimuli.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Flaten, A.
Secondary author(s):
Firan, A., Blumenthal, T.
Document type:
Article
Number of reproductions:
1
Reference:
Flaten, M.A., Firan, A., & Blumenthal, T.D. (2016). Somatosensory pain is not reliably modulated by weak acoustic stimuli. International Journal of Psychophysiology, 99, 114-120. https://doi.org/10.1016/j.ijpsycho.2015.12.004
2-year Impact Factor: 2.582|2016
Times cited: 5|2025-09-16
Indexed document: Yes
Quartile: Q2
Keywords: Pain / Prepulse inhibition / Placebo / Nocebo / Startle / Electromyography
DocumentPET imaging of dopamine neurotransmission during EEG neurofeedback2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-442
Location: BF-GMS
Title:
442 - Neurochemical Substrates of Neurofeedback
Duration: 2016-04 - 2020-09
Researcher(s):
Tomas Ros, Nathalie Ginovart
Institution(s): Interfacultary Center for Neuroscience, University of Geneva (Switzerland); Division of Nuclear Medicine, University Hospitals Geneva (Switzerland)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Ros, T.
Secondary author(s):
Ginovart, N
Number of reproductions:
1
Keywords:
Neurofeedback / Electroencephalogram / Positron emission tomography / Dopamine / Psychophysiology

Reference code: PT/FB/BL-2014-442.02
Location: BF-GMS
Title:
PET imaging of dopamine neurotransmission during EEG neurofeedback
Publication year: 2021
URL:
https://www.frontiersin.org/articles/10.3389/fphys.2020.590503/full
Abstract/Results: ABSTRACT:
Neurofeedback (NFB) is a brain-based training method that enables users to control their own cortical oscillations using real-time feedback from the electroencephalogram (EEG). Importantly, no investigations to date have directly explored the potential impact of NFB on the brain’s key neuromodulatory systems. Our study’s objective was to assess the capacity of NFB to induce dopamine release as revealed by positron emission tomography (PET). Thirty-two healthy volunteers were randomized to either EEG-neurofeedback (NFB) or EEG-electromyography (EMG), and scanned while performing self-regulation during a single session of dynamic PET brain imaging using the high affinity D2/3 receptor radiotracer, [18F]Fallypride. NFB and EMG groups down-regulated cortical alpha power and facial muscle tone, respectively. Task-induced effects on endogenous dopamine release were estimated in the frontal cortex, anterior cingulate cortex, and thalamus, using the linearized simplified reference region model (LSRRM), which accounts for time-dependent changes in radiotracer binding following task initiation. Contrary to our hypothesis of a differential effect for NFB vs. EMG training, significant dopamine release was observed in both training groups in the frontal and anterior cingulate cortex, but not in thalamus. Interestingly, a significant negative correlation was observed between dopamine release in frontal cortex and pre-to-post NFB change in spontaneous alpha power, suggesting that intra-individual changes in brain state (i.e., alpha power) could partly result from changes in neuromodulatory tone. Overall, our findings constitute the first direct investigation of neurofeedback’s effect on the endogenous release of a key neuromodulator, demonstrating its feasibility and paving the way for future studies using this methodology.
Accessibility: Document exists in file
Language:
eng
Author:
Ros, T.
Secondary author(s):
Kwiek, J., Andriot, T., Michela, A.,, Vuilleumier, P., Garibotto, V., Ginovart, N.
Document type:
Article
Number of reproductions:
1
Reference:
Ros, T., Kwiek, J., Andriot, T., Michela, A., Vuilleumier, P., Garibotto, V., & Ginovart, N. (2021). PET imaging of dopamine neurotransmission during EEG neurofeedback. Fronties in Physiology, 11: 590503. https://doi.org/10.3389/fphys.2020.590503
2-year Impact Factor: 4.755|2021
Times cited: 9|2025-09-20
Indexed document: Yes
Quartile: Q1
Keywords: Dopamine / Neurofeedback / Positron emission tomography / Electromyography / Electroencephalography / Fallypride

PET imaging of dopamine neurotransmission during EEG neurofeedback

PET imaging of dopamine neurotransmission during EEG neurofeedback
DocumentRedefining the decisional components of motor responses: Evidence from lexical and object decision tasks2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-079
Location: BF-GMS
Title:
079 - Redefining the boundaries between cognition and action through the psychophysiological investigation of binary decisions
Duration: 2021-02 - 2023-09
Researcher(s):
Michele Scaltritti, Simone Sulpizio
Institution(s): Department of Psychology and Cognitive Science, University of Trento, Rovereto (Italy); Università degli Studi di Milano-Bicocca (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Scaltritti, M.
Secondary author(s):
Sulpizio, S.
Number of reproductions:
1
Keywords:
Decision making / Motor control / Electroencephalogram (EEG) / Cortico-muscular coherence / Psychophysiology

Reference code: PT/FB/BL-2020-079.02
Location: BF-GMS
Title:
Redefining the decisional components of motor responses: Evidence from lexical and object decision tasks
Publication year: 2023
URL:
https://doi.org/10.1037/xhp0001113
Abstract/Results: ABSTRACT:
Models of decision making focusing on two-alternative choices have classically described motor-response execution as a nondecisional stage that serially follows the termination of decision processes. Recent evidence, however, points toward a more continuous transition between decision and motor processes. We investigated this transition in two lexical decisions and one object decision task. By recording the electromyographic (EMG) signal associated with the muscle responsible for the manual responses (i.e., button press), we partitioned single-trial reaction times into premotor (the time elapsing from stimulus onset until the onset of the EMG burst) and motor times (the time elapsing from the onset of the EMG burst and the button press), with the latter measuring response execution. Responses were slower for pseudowords and pseudo-objects compared to words and real objects. Importantly, these effects were reliable even at the level of motor time measures. Differently, despite the reliable effect at the level of reaction times and premotor times, there was no difference in motor times between high- and low-frequency words. Although these results, in line with recent evidence, challenge a purely noncognitive characterization of motor-response execution, they further suggest that motor times may selectively capture specific decisional components, which we identify with late-occurring verification and/or control mechanisms.
Accessibility: Document exists in file
Language:
eng
Author:
Scaltritti, M.
Secondary author(s):
Giacomoni, F., Job, R., Sulpizio, S.
Document type:
Article
Number of reproductions:
1
Reference:
Scaltritti, M., Giacomoni, F., Job, R., & Sulpizio, S. (2023). Redefining the decisional components of motor responses: Evidence from lexical and object decision tasks. Journal of Experimental Psychology: Human Perception and Performance, 49(6), 835-851. https://doi.org/10.1037/xhp0001113
2-year Impact Factor: 2.1|2023
Times cited: 7|2025-09-26
Indexed document: Yes
Quartile: Q2
Keywords: Decision making / Lexical decision / Motor-response execution / Electromyography / Lexicality

Redefining the decisional components of motor responses: Evidence from lexical and object decision tasks

Redefining the decisional components of motor responses: Evidence from lexical and object decision tasks
File316 - Psychophysiological aspects of the doctor-patient relationship: The role of nonverbal behaviors in placebo and nocebo effects2025-04

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2024
Location: BF-GMS
Title:
2024 Grants
Start date: 2025-01

Reference code: PT/FB/BL-2024-316
Location: BF-GMS
Title:
316 - Psychophysiological aspects of the doctor-patient relationship: The role of nonverbal behaviors in placebo and nocebo effects
Duration: 2025-04
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Ghazaleh Akbarzadeh, Mollie Ruben, Charlotte Fiskum
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); Department of Psychology, Rhode Island University (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Language: eng
Notes:
Ongoing project
Author: Flaten, M. A.
Secondary author(s):
Daniali, H., Akbarzadeh, G., Ruben, M., Fiskum, C.
Number of reproductions:
1
Keywords:
Placebo effects / Nocebo effects / Heart rate variability / Electromyography / Psychophysiology