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DocumentThe medullary dorsal reticular nucleus enhances the responsiveness of spinal nociceptive neurons to peripheral stimulation in the rat2003

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-067
Location: Arquivo PCA - Pasta 10/2000
Title:
067 - Pain control from the brain. Novel approaches of chronic pain treatment through manipulation of supraspinal areas
Duration: 2000-12 - 2003-12
Researcher(s):
Deolinda Lima, Isaura Ferreira Tavares, Armando Alberto da Nova Pinto de Almeida, Christophe Dugast, Vasco Miguel Clara Lopes Galhardo, Marta Sofia Carvalho Teixeira Pinto
Institution(s): Instituto de Histologia e Embriologia da Faculdade de Medicina do Porto (Portugal)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
1 Article
Language: eng
Author:
Lima, D.
Secondary author(s):
Tavares, I., Almeida, A., Dugast, C., Galhardo, V., Pinto, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain

Reference code: PT/FB/BL-2000-067.02
Location: Arquivo PCA - Pasta 10/2000
Title:
The medullary dorsal reticular nucleus enhances the responsiveness of spinal nociceptive neurons to peripheral stimulation in the rat
Publication year: 2003
URL:
http://onlinelibrary.wiley.com/doi/10.1046/j.1460-9568.2003.02782.x/abstract
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=213&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
Single-unit spinal recordings combined with application of glutamate into the medullary dorsal reticular nucleus were used to assess the action of this nucleus upon deep dorsal horn neurons in rats. Injection of high glutamate concentrations (10 and 100 mm) induced a dramatic and long-lasting increase of the responses of wide-dynamic range neurons to electrical stimulation of the sciatic nerve in the noxious range, without affecting ongoing discharges. Post-stimulus time histograms revealed that this increase concerned the post-discharge, but not A- or C-fibre-mediated responses, which remained unchanged independently of the stimulation frequency applied. The onset of the glutamate-induced response enhancement occurred with a concentration-dependent time delay and developed slowly until its maximum. These data indicate that the medullary dorsal reticular nucleus exerts a facilitating action upon deep dorsal horn wide-dynamic range neurons by enhancing their capacity to respond to peripheral stimulation through prolongation of their discharge. This action is accompanied by the strengthening of wind-up of deep dorsal horn wide-dynamic range neurons, hence providing a plausible substrate for chronic pain states. These results are in agreement with previous behavioural studies suggesting a pronociceptive role for the dorsal reticular nucleus [Almeida et al. (1996) Brain Res. Bull., 39, 7-15; Almeida et al. (1999) Eur. J. Neurosci., 11, 110-122], and support the involvement of a reverberating circuit, previously described in morphological studies [Almeida et al. (1993) Neuroscience, 55, 1093-1106; Almeida et al. (2000) Eur. J. Pain, 4, 373-387], which probably operates only at a certain threshold of activation.
Accessibility: Document does not exist in file
Language:
eng
Author:
Dugast, C.
Secondary author(s):
Almeida, A., Lima, D.
Document type:
Article
Number of reproductions:
1
Reference:
Dugast, C., Almeida, A., & Lima, D. (2003). The medullary dorsal reticular nucleus enhances the responsiveness of spinal nociceptive neurons to peripheral stimulation in the rat. European Journal of Neuroscience, 18(3), 580-588. doi: 10.1046/j.1460-9568.2003.02782.x
2-year Impact Factor: 3.872|2003
Times cited: 25|2020-03-09
Indexed document: Yes
Quartile: Q1
Keywords: Electrophysiology / Facilitation / Pain / Wide-dynamic range / Wind-up

DocumentCognitive processes during adaptive and perceptive tasks1998

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1996
Location: Arquivo PCA - Pastas 1 a 8/1996
Title:
1996 Grants
Start date: 1997-01 - 2005-05
Dimension/support:
8 caixas de arquivo

Reference code: PT/FB/BL-1996-027
Location: Arquivo PCA - Pasta 7/1996
Title:
027 - Investigação teórica e experimental de processos perceptivos cognitivos e afectivos e estruturas da personalidade e aplicações em psicopatologia e reabilitação em baixa visão
Duration: 1997-01 - 2001-10
Researcher(s):
José Luís Simões da Fonseca, Luísa Figueira, Carmen Araújo, José Manuel Félix da Costa, Maria da Purificação Horta, Isabel Barahona Fernandes Simões da Fonseca, Sílvia Ouakinin, José Barahona da Fonseca
Institution(s): Faculdade de Medicina de Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Articles (by research team)
Articles (other authors outside research team)
Doctoral thesis
Language: por
Author:
Fonseca, J. S.
Secondary author(s):
Figueira, I., Araújo, C., Costa, J., Horta, M., Fonseca, I. B., Ouakinin, S., Fonseca, J. B.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes / Emotion

Reference code: PT/FB/BL-1996-027.14
Location: Arquivo PCA - Pasta 7/1996
Title:
Cognitive processes during adaptive and perceptive tasks
Publication year: 1998
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/2%C2%BA_simposio.a108.html
Accessibility: Document does not exist in file
Language:
eng
Author:
Fonseca, J. S.
Secondary author(s):
Fonseca, I. B., Fonseca, J. B., Araújo, C.
Document type:
Conference paper
Number of reproductions:
1
Reference:
Fonseca, J. S., Fonseca, I. B., Fonseca, J. B., & Araújo, C. (1998). Cognitive processes during adaptive and perceptive tasks. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 2nd Symposium of Fundação Bial (pp. 237-244). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Electrophysiology / Affective states / Electroencephalogram (EEG)

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DocumentPsychophysiological correlates of sexually and non-sexually motivated attention to film clips in a workload task2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-089
Location: Arquivo PCA - Pasta 11/2008
Title:
089 - The Neuropsychophysiological Basis of Empathy: The role of neuroendocrine, autonomic and central nervous system variables
Duration: 2009-01 - 2012-03
Researcher(s):
Óscar Filipe Coelho Neves Gonçalves, Patrícia Silva, Ana Pinheiro
Institution(s): Cipsi – Centro de Investigação em Psicologia, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Articles
Language: eng, por
Author:
Gonçalves, O.
Secondary author(s):
Silva, P., Pinheiro, A.
Keywords:
Psychophysiology / Emotion / Empathy / Assessment tools / Psychoneuroimmunology / Endocrinology / Brain structure and function

Reference code: PT/FB/BL-2008-089.01
Location: Arquivo PCA - Pasta 11/2008
Title:
Psychophysiological correlates of sexually and non-sexually motivated attention to film clips in a workload task
Publication year: 2011
URL:
http://connection.ebscohost.com/c/articles/73936889/psychophysiological-correlates-sexually-non-sexually-motivated-attention-film-clips-workload-task
Abstract/Results: ABSTRACT:
Some authors have speculated that the cognitive component (P3) of the Event-Related Potential (ERP) can function as a psychophysiological measure of sexual interest. The aim of this study was to determine if the P3 ERP component in a workload task can be used as a specific and objective measure of sexual motivation by comparing the neurophysiologic response to stimuli of motivational relevance with different levels of valence and arousal. A total of 30 healthy volunteers watched different films clips with erotic, horror, social-positive and social-negative content, while answering an auditory oddball paradigm. Erotic film clips resulted in larger interference when compared to both the social-positive and auditory alone conditions. Horror film clips resulted in the highest levels of interference with smaller P3 amplitudes than erotic and also than social-positive, social-negative and auditory alone condition. No gender differences were found. Both horror and erotic film clips significantly decreased heart rate (HR) when compared to both social-positive and social-negative films. The erotic film clips significantly increased the skin conductance level (SCL) compared to the social-negative films. The horror film clips significantly increased the SCL compared to both social-positive and social-negative films. Both the highly arousing erotic and non-erotic (horror) movies produced the largest decrease in the P3 amplitude, a decrease in the HR and an increase in the SCL. These data support the notion that this workload task is very sensitive to the attentional resources allocated to the film clip, although they do not act as a specific index of sexual interest. Therefore, the use of this methodology seems to be of questionable utility as a specific measure of sexual interest or as an objective measure of the severity of Hypoactive Sexual Desire Disorder.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Carvalho, S.
Secondary author(s):
Leite, J., Galdo-Álvarez, S., Gonçalves, O.
Document type:
Article
Reference:
Carvalho, S., Leite, J., Galdo-Álvarez, S., & Gonçalves, O. (2011). Psychophysiological correlates of sexually and non-sexually motivated attention to film clips in a workload task. PLoS ONE, 6(12), e29530. doi: 10.1371/journal.pone.0029530
2-year Impact Factor: 4.092|2011
Times cited: 6|2020-03-10
Indexed document: Yes
Quartile: Q1
Keywords: Psychosomatic disorders / Evoked potentials / Psychophysiology / Electrophysiology / Erotic films / Sexual desire disorders

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DocumentThe Syntactic and Semantic Processing of Mass and Count Nouns: An ERP Study2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-146
Location: Arquivo PCA - Pasta 13/2008
Title:
146 - Life-Span Changes in Electrophysiological Patterns Associated with Temporal Discrimination
Duration: 2009-01 - 2012-02
Researcher(s):
Patrizia Bisiacchi, Giovanni Sparacino, Vincenza Tarantino, Sami Schiff
Institution(s): Department of General Psychology, University of Padua (Italy)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Articles
Unpublished documents
Written consent forms of participants
Language: eng
Author:
Bisiacchi, P.
Secondary author(s):
Sparacino, G., Tarantino, V., Schiff, S.
Keywords:
Psychophysiology / Developmental psychology / Cognitive processes / Brain structure and function / Biopsychological problems / Childhood and adolescent disorders / Neurodegenerative disorders / Diseases/Injuries / Assessment tools

Reference code: PT/FB/BL-2008-146.03
Location: Arquivo PCA - Pasta 13/2008
Title:
The Syntactic and Semantic Processing of Mass and Count Nouns: An ERP Study
Publication year: 2011
URL:
http://connection.ebscohost.com/c/articles/73890227/syntactic-semantic-processing-mass-count-nouns-erp-study
Abstract/Results: ABSTRACT:
The present study addressed the question of whether count and mass nouns are differentially processed in the brain. In two different ERP (Event-Related Potentials) tasks we explored the semantic and syntactic levels of such distinction. Mass and count nouns typically differ in concreteness, hence the effect of this important variable was factorially examined in each task. Thus the stimuli presented were: count concrete, count abstract, mass concrete or mass abstract. The first experiment (concrete/abstract semantic judgment task) involved the interaction between the N400 concreteness effect and the Mass/ Count condition, revealing a substantial effect between mass and count nouns at the semantic level. The second experiment (sentence syntactic violation task) showed a Mass/Count distinction on left anterior negativity (LAN) and on P600 components, confirming the difference at the syntactic level. This study suggests that the brain differentiates between count and mass nouns not only at the syntactic level but also at the semantic level. Implications for our understanding of the brain mechanisms underlying the Mass/Count distinction are discussed.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Chiarelli, V.
Secondary author(s):
El Yagoubi, R., Mondini, S., Bisiacchi, P., Semenza, C.
Document type:
Article
Reference:
Chiarelli, V., El Yagoubi, R., Mondini, S., Bisiacchi, P., Semenza, C. (2011). The Syntactic and Semantic Processing of Mass and Count Nouns: An ERP Study. PLoS ONE, 6(10), 1-15. doi: 10.1371/journal.pone.0025885
2-year Impact Factor: 4.092|2011
Times cited: 9|2020-03-11
Indexed document: Yes
Quartile: Q1
Keywords: Evoked potentials / Electrophysiology / Biopotentials / Electroencephalography / Semantics / Verbal learning

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DocumentDoes meditation practice modulate the dynamics of attentional neural networks? An EEG study2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-030
Location: Arquivo PCA - Pasta 2/2008
Title:
030 - Does meditation practice modulate the dynamics of attentional neural networks? An EEG study
Duration: 2009-09 - 2011-04
Researcher(s):
Peter Malinowski, Thomas Gruber, Gernot G. Supp
Institution(s): Liverpool John Moores University, School of Psychology (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Articles
Language: eng
Author:
Malinowski, P.
Secondary author(s):
Gruber, T., Supp, G.
Keywords:
Psychophysiology / Altered states of consciousness / Meditation / Cognitive processes / Attention

Reference code: PT/FB/BL-2008-030.09
Location: Arquivo PCA - Pasta 2/2008
Title:
Does meditation practice modulate the dynamics of attentional neural networks? An EEG study
Publication year: 2012
URL:
http://www.bial.com/imagem/Bial%20Sonhos%20Miolo_Total%20Bolsas.pdf
Abstract/Results: ABSTRACT:
Objectives: Mindfulness based meditation practices involve various attentional skills, including the
ability to sustain and focus one’s attention. During a simple mindful breathing practice, sustained
attention is required to maintain focus on the breath while cognitive control is required to detect
mind wandering. As the refinement of attentional functions is considered to significantly
contribute to the positive effects of meditation practice, the aim of this project was to investigate
whether brief regular mindfulness meditation practice would result in improvements in the self
regulation of attention and foster changes in neuronal activity related to attentional control.
Methods: A longitudinal randomised control group EEG study was conducted. At baseline (T1), 40
meditation naïve participants were randomised into a wait list group and a meditation group, who
received three hours mindfulness meditation training. 28 participants remained in the final
analysis. At T1, after 8 weeks (T2) and after 16 weeks (T3), all participants performed a
computerized Stroop task (a measure of attentional control) while the 64-channel EEG was
recorded. Between T1 and T3 the meditators were requested to meditate daily for ten minutes.
Results: Event-related potential (ERP) analysis highlighted two between group effects that
developed over the course of the 16-week mindfulness training. An early effect at left and right
posterior sites 160 – 240 ms post stimulus indicates that meditation practice improved the
focusing of attentional resources. A second effect at central posterior sites 310 – 380 ms post
stimulus reflects that meditation practice reduced the recruitment of resources during object
recognition processes, especially for incongruent stimuli. Scalp topographies and source analyses
(VARETA) indicate relevant changes in neural sources, pertaining to left medial and lateral
occipitotemporal areas for the early effect and right lateral occipitotemporal and inferior temporal
areas for the later effect.
Discussion and Conclusions: The results suggest that mindfulness meditation may alter the
efficiency of allocating cognitive resources, leading to improved self regulation of attention. That
meditating for only 10 minutes per day leads to significant changes in neural activity highlights the
potential mindfulness practice may have for the everyday user.
Accessibility: Document does not exist in file
Language:
eng
Author:
Malinowski, P.
Secondary author(s):
Gruber, T., Supp, G.
Document type:
Conference abstract
Reference:
Malinowski, P., Gruber, T., Supp, G. (2012). Does meditation practice modulate the dynamics of attentional neural networks? An EEG study. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 9th Symposium of Fundação Bial (p. 16/63). Porto: Fundação Bial.
Indexed document: No
Keywords: Meditation / Mindfulness / Cognitive control / Electrophysiology / Attention

Novo ficheiro

Novo ficheiro

DocumentSocial-stimulus-evoked activity in the female mouse hypothalamus: Influence of the reproductive cycle 2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-180
Location: Arquivo PCA - Pasta 16/2010
Title:
180 - Neuronal mechanisms underlying sex hormone-dependent switching of sexual receptivity
Duration: 2011-05 - 2013-07
Researcher(s):
Kensaku Nomoto, Susana Quelhas Lima
Institution(s): Champalimaud Foundation, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Nomoto, K.
Secondary author(s):
Lima, S.
Keywords:
Psychophysiology / Affective and social behavior / Animal behavior / Sexual behavior / Brain structure and function

Reference code: PT/FB/BL-2010-180.03
Location: Arquivo PCA - Pasta 16/2010
Title:
Social-stimulus-evoked activity in the female mouse hypothalamus: Influence of the reproductive cycle
Publication year: 2012
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=8f618c5a-55eb-4fdc-9857-ba3eeb69220a&cKey=8496f7fc-39f7-48ce-ad0e-ac19bc1fbac6&mKey=%7b70007181-01C9-4DE9-A0A2-EEBFA14CD9F1%7d
Abstract/Results: ABSTRACT:
In many mammalian species, ovarian hormones fluctuate during the reproductive cycle, heavily influencing female behavior. In rodents, changes in sexual receptivity are one of the most fundamental changes across the reproductive cycle. While, for instance, a female rodent is sexually receptive during the proestrous phase, she rejects copulation during all other phases of the reproductive cycle. It is well accepted that the ventromedial hypothalamus (VMH) plays a critical role in the control of female sexual behavior. However it is poorly understood how the activity of VMH neurons is coordinated and mediates behavioral changes across the reproductive cycle. To address this issue, we performed extracellular single-unit recording experiments in behaving female mice across the reproductive cycle. The test animal was allowed to interact freely with the stimulus animals that were introduced into the arena sequentially. In agreement with a previous study in male mice, we found VMH neurons that significantly responded with increased or decreased activity during social investigation compared to the activity during the control period. We classified VMH neurons based on their response pattern against the male stimuli: excited, inhibited, or no response. Our results showed that the proportion of male-inhibited neurons during the proestrous phase (7/20, 35%) was higher than those during the estrous and diestrous phases (4/29, 14% and 4/26, 15%, respectively). These preliminary results suggest that changes in the balance of excitation and inhibition in VMH neurons may underlie behavioral changes across the reproductive cycle.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nomoto, K.
Secondary author(s):
Lima, S.
Document type:
Online abstract
Reference:
Nomoto, K., & Lima, S. (2012). Social-stimulus-evoked activity in the female mouse hypothalamus: Influence of the reproductive cycle. Program No. 401.09/FFF47. Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Abstract retrieved from http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=8f618c5a-55eb-4fdc-9857-ba3eeb69220a&cKey=8496f7fc-39f7-48ce-ad0e-ac19bc1fbac6&mKey=%7b70007181-01C9-4DE9-A0A2-EEBFA14CD9F1%7d
Indexed document: No
Keywords: Hypothalamus / Sexual behavior / Electrophysiology

DocumentA vision for medical research in the new era of complexity: A new multimodal integrative paradigm

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/E
Entity holding: BIAL Foundation
Title: Documentation and Information Center
History: Books that are part of the documentation center

Reference code: PT/FB/E/053
Title: A vision for medical research in the new era of complexity: A new multimodal integrative paradigm
Número de inventário: M-0054
Local: Porto
Publisher: Laboratórios Bial
Date: 2010
Pag., vols.: 195 p.
Illustration: il., graphs
Dimension/support: 24 cm
Accessibility: Document exists in archive
Copyright/Reproduction:
By permission
Language:
eng
Notes:
Grande Prémio Bial de Medicina 2008
Edition: 1ª ed.
Collection: (Bial ; 39)
Author: Castelo-Branco, M.
Document type:
Book
Keywords:
Medical research / Complexity / Neurophysiology / Brain imaging / In vivo imaging / Electrophysiology / Psychophysics / Multimodal techniques

File427 - Gliogenesis control of brain neuroplasticity, neurophysiology and cognitive function2015-09

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-427
Location: BF-GMS
Title:
427 - Gliogenesis control of brain neuroplasticity, neurophysiology and cognitive function
Duration: 2015-09
Researcher(s):
Luísa Alexandra Meireles Pinto, Ana Rita Machado dos Santos, António Maria Restolho Mateus Pinheiro, Cristina Joana Moreira Marques, Joana Sofia da Silva Correia, João Filipe Pedreira de Oliveira, João Miguel Bessa Peixoto, Nuno Dinis Alves, Patrícia Carvalho Patrício, Vítor Manuel da Silva Pinto
Institution(s): Life and Health Sciences Research Institute - ICVS, University of Minho and ICVS/3B's- Government Associate Laboratory, Braga (Portugal); Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Language: eng
Author:
Pinto, L.
Secondary author(s):
Santos, A., Pinho, A., Marques, A., Correia, J., Oliveira, J. F., Peixoto, J., Alves, N., Patrício, P., Pinto, V.
Keywords:
Astrogliogenesis / Neuroplasticity / Cognition / Electrophysiology / Psychophysiology

DocumentFinal report - Translation of neuron-glia interactions in complex cognitive functions2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-061
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
061 - Translation of neuron-glia interactions in complex cognitive functions
Duration: 2011-05 - 2015-07
Researcher(s):
João Filipe Pedreira de Oliveira, Nuno Sérgio Mendes Dias, Luis Ricardo Monteiro Jacinto
Institution(s): Instituto de Investigação em Ciências da Vida e da Saúde (ICVS), Escola de Ciências da Saúde, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 Articles
1 Poster
Language: eng
Author:
Oliveira, J. F.
Secondary author(s):
Dias, N., Jacinto, L. R.
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function

Reference code: PT/FB/BL-2010-061.01
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
Final report - Translation of neuron-glia interactions in complex cognitive functions
Publication year: 2015
URL:
https://www.bial.com/imagem/Bolsa6110_22092015.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
The classical paradigm that cognitive processing is exclusively neuronal has been challenged in the past ten years by an exciting body of evidence. Indeed, the importance of glial cells is rising due to emerging data supporting dynamic neuron-glia interactions, in which a cross-talk between astrocytes and neurons complements and modulates the communication between pre- and post-synaptic structures.
AIM
The main research objective of this project is to assess the interplay between astrocytes and neurons underlying cognitive function in the brain.
METHODS
We have used complementary state-of-the-art techniques such as in vivo electrophysiology, innovative behavior, anatomical and molecular analysis, to seek a role of astrocytes in the computation of cognitive functions.
RESULTS/CONCLUSIONS
Astrocytes appear as critical elements of the neuroglial network, whose function is required for the normal hippocampal function. This information accounts for new knowledge on the cognitive computation and this new player may account also for the cognitive decline observed for instance in ageing or pathological processes, arising as a possible therapeutic target for the treatment of prevention of cognitive deficits.
Accessibility: Document exists in file
Language:
eng
Author:
Oliveira, J. F.
Document type:
Final report
Indexed document:
No
Keywords: Astrocyte / Cognition / Neural circuits / Behavior / Electrophysiology

Final report - Translation of neuron-glia interactions in complex cognitive functions

Final report - Translation of neuron-glia interactions in complex cognitive functions

DocumentInsights into local properties and synchrony of sleep spindles from ECoG in humans 2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-220
Location: Arquivo PCA - Pasta 15/2012
Title:
220 - Consciousness disconnects during sleep
Duration: 2013-04 - 2016-05
Researcher(s):
Giovanni Piantoni
Institution(s): Cortical Physiology Lab, Massachusets General Hospital, Harvard Medical School (USA) and Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final reports
1 article
Submitted papers
Language: eng
Author:
Piantoni, G.
Keywords:
Psychophysiology / Brain structure and function / Sleep and dreams

Reference code: PT/FB/BL-2012-220.03
Location: Arquivo PCA - Pasta 15/2012
Title:
Insights into local properties and synchrony of sleep spindles from ECoG in humans
Publication year: 2014
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=4da09ec6-f098-4bf1-9af3-8457926fe748&cKey=fefbc49d-14b7-4304-a5b2-616c6815d739&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Abstract/Results: ABSTRACT:
During non-REM sleep, neuronal firing is grouped by the slow oscillations at around 1 Hz, and sleep spindles, 0.5-2s long bursts of oscillatory activity between 11 and 18 Hz. Spindles are thought to arise from the interplay between thalamic and cortical neurons and are hypothesized to be involved in a wide variety of fundamental processes including the solidification of learning during sleep. However many of the physiological mechanisms and characteristics of spindles remain poorly understood. The spatial extent of spindle activity, as one key feature, has been the object of substantial debate, with conflicting evidence pointing both to an increase in synchronization, assessed with scalp EEG, and to strong regional localization, as measured by MEG and intraparenchymal depth electrode recordings (iEEG). Here, we examine spindle localization and synchrony across broad areas of neocortex using recordings from, on average, 80 electrodes (ECoG) placed directly on the pial surface in six patients undergoing evaluation for intractable epilepsy. The research was approved by the local institutional review board and electrode placement was determined solely by clinical criteria. At least one hour of visually scored sleep was included in the analysis. Spindles were automatically detected on each electrode independently, based on custom code. Spindles were considered synchronous when two spindles on separate channels overlapped in time. We observed that spindles were more likely than expected by chance to appear at the same time over multiple cortical locations. However, when we estimated the distribution of spindles in relation to the number of active electrodes, we observed that there was a strong positive skew. This indicates that most spindles were synchronous only in one or a few channels at the same time but some spindles were widely distributed. This distinction between focal spindles and distributed spindles was further investigated by measuring the spreading over cortical regions with a 3D reconstruction of the electrode locations and by comparing it with the underlying anatomical structures. These results indicate a dynamic interplay between local properties of focal spindles and widespread synchrony of global spindles. We suggest that the multiple spatial scales at which sleep oscillations operate might provide a flexible framework to support the many functions ascribed to sleep and to spindles in particular, such as sensory gating, memory consolidation, and synaptic homeostasis.
Accessibility: Document does not exist in file
Language:
eng
Author:
Piantoni, G.
Secondary author(s):
Halgren, E., Cash, S.
Document type:
Online abstract
Reference:
Piantoni, G., Halgren, E., & Cash, S. (2014, November). Insights into local properties and synchrony of sleep spindles from ECoG in humans. Poster presented at the 2014 Society for Neuroscience meeting, Washington, D. C. Abstract retrieved from http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=4da09ec6-f098-4bf1-9af3-8457926fe748&cKey=fefbc49d-14b7-4304-a5b2-616c6815d739&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Indexed document: No
Keywords: Sleep / Electrophysiology / Oscillations

DocumentBonsai: an event-based framework for processing and controlling data streams2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-190
Location: Arquivo PCA - Pasta 16/2012
Title:
190 - Interfacing Technology with the Brain: Novel materials for implantable neural devices
Duration: 2013-06 - 2016-09
Researcher(s):
Adam Kampff, Elvira Fortunato, Pedro Barquinha, Joana Neto, Joana Nogueira
Institution(s): Fundação Champalimaud and CENIMAT - Materials Research Center, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
Language: eng
Author:
Kampff, A.
Secondary author(s):
Fortunato, E., Barquinha, P., Neto, J., Nogueira, J.
Keywords:
Psychophysiology / Brain structure and function / Assessment tools

Reference code: PT/FB/BL-2012-190.02
Location: Arquivo PCA - Pasta 16/2012
Title:
Bonsai: an event-based framework for processing and controlling data streams
Publication year: 2015
URL:
http://journal.frontiersin.org/article/10.3389/fninf.2015.00007/abstract
Abstract/Results: ABSTRACT:
The design of modern scientific experiments requires the control and monitoring of many different data streams. However, the serial execution of programming instructions in a computer makes it a challenge to develop software that can deal with the asynchronous, parallel nature of scientific data. Here we present Bonsai, a modular, high-performance, open-source visual programming framework for the acquisition and online processing of data streams. We describe Bonsai's core principles and architecture and demonstrate how it allows for the rapid and flexible prototyping of integrated experimental designs in neuroscience. We specifically highlight some applications that require the combination of many different hardware and software components, including video tracking of behavior, electrophysiology and closed-loop control of stimulation.
Accessibility: Document exists in file
Language:
eng
Author:
Lopes, G.
Secondary author(s):
Bonacchi, N., Frazão, J., Neto, J., Atallah, B., Soares, S., Moreira, L., Matias, S., Itskov, P. M., Correia, P.A., Medina, R. E., Calcaterra, L., Dreosti, E., Paton, J., Kampff, A.
Document type:
Article
Reference:
Lopes, G., Bonacchi, N., Frazão, J., Neto, J. P., Atallah, B. V., Soares, S., ... Kampff, A. (2015). Bonsai: an event-based framework for processing and controlling data streams. Frontiers in neuroinformatics. 9:7. doi: 10.3389/fninf.2015.00007
2-year Impact Factor: 3.047|2015
Times cited: 45|2020-03-12
Indexed document: Yes
Quartile: Q1
Keywords: Rapid prototyping / Data acquisition system / Data stream processing / Parallel processing / Open-source / Video tracking / Electrophysiology / Behavior control

Bonsai: an event-based framework for processing and controlling data streams

Bonsai: an event-based framework for processing and controlling data streams

DocumentDissociation between amplitude and synchrony of brain activity in a human model of loss of coherence2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-132
Location: Arquivo PCA - Pasta 11/2012
Title:
132 - A direct test of the binding by synchrony hypothesis in humans: the neural correlates of coherent object perception
Duration: 2013-11 - 2016-01
Researcher(s):
Miguel Castelo-Branco, Maria Ribeiro, João Duarte, Gabriel Costa
Institution(s): IBILI, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress reports
Final report
Article
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Ribeiro, M., Duarte, J., Costa, G.
Keywords:
Psychophysiology / Cognitive processes / Perception / Brain structure and function

Reference code: PT/FB/BL-2012-132.13
Location: Arquivo PCA - Pasta 11/2012
Title:
Dissociation between amplitude and synchrony of brain activity in a human model of loss of coherence
Publication year: 2014
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=44b49305-57b1-4f13-8b1a-4918517cf24d&cKey=380ee307-f56e-45fe-92eb-1ba81f66558a&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Abstract/Results: ABSTRACT:
The central coherence hypothesis was proposed to explain abnormal cognition in ASD and Williams syndrome (WS), a neurodevelopmental disorder linked with autism, and the most clearcut model for impaired central coherence. We studied this model of impaired holistic processing to test a functional role for neural synchrony using EEG and a set of experimental tasks requiring visual integration at different complexity levels. We tested whether synchronization and amplitude modulation of gamma patterns can be segregated in this model. We used a set of experimental tasks requiring feature integration at different complexity levels (static and motion, 2D and 3D face stimuli) and compared gamma-band activity and synchrony between WS patients (n=9; 21.44 ± 2.30 years) and a normal control group. WS diagnostic was confirmed based on clinical and genetic criteria. Control participants (n=8) were matched on chronological age, gender and handedness. EEG was recorded using a SynAmps2 64 channel system, at 2kHz and processed offline. Data were corrected and segmented into epochs locked to the stimulus onset (-0.5s to 1.5s) for all conditions. Time-frequency (TF) and phase synchrony analysis were performed as in Uhlhaas et al., 2006. TF analysis was carried out in Matlab® across distinct defined electrode clusters (Parietal, Temporal, Parieto-Occipital and Occipital) for frequencies ranging from 10Hz to 90Hz. Phase-locking values (PLV) were computed between all possible pairs of electrodes, and the stability of phase differences was evaluated through all the trials. For the statistical comparison between groups, Wilcoxon ranksum tests were carried out including false discovery rate (FDR) correction for multiple comparisons. Groups differed (p<0.02 FDR corrected) in three main frequency sub-bands: controls showed higher synchrony at 10-22Hz and 30-43Hz and WS showed increased synchrony for the 62-79Hz frequency band. The condition requiring the highest level of integration (SFM) was the one associated with the most dramatic loss of synchrony in the WS group. This suggests a dependence on visual complexity and integration requirements and is in line with the proposal that perception requires mechanisms for integration and feature binding that rely on the neuronal synchrony. Moreover, synchrony was reduced in WS across stimulus conditions in striking contrast with increased amplitude modulation at 25-45Hz. This signature of dramatic loss of synchrony as opposed to concomitantly increased activation (amplitude), provides evidence that synchrony underlies central coherence irrespective of power changes in gamma activity.
Accessibility: Document does not exist in file
Language:
eng
Author:
Castelhano, J.
Secondary author(s):
Bernardino, I., Rebola, J., Castelo-Branco, M.
Document type:
Online abstract
Reference:
Castelhano, J., Bernardino, I., Rebola, J., & Castelo-Branco, M. (2014, November). Dissociation between amplitude and synchrony of brain activity in a human model of loss of coherence. Poster presented at Society for Neuroscience 2014, Washington, DC. Online abstract available at http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=44b49305-57b1-4f13-8b1a-4918517cf24d&cKey=380ee307-f56e-45fe-92eb-1ba81f66558a&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Indexed document: No
Keywords: Electrophysiology / Oscillations / Synchrony

DocumentSpatiotemporal evolution of the sleep spindle in human neocortex 2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-220
Location: Arquivo PCA - Pasta 15/2012
Title:
220 - Consciousness disconnects during sleep
Duration: 2013-04 - 2016-05
Researcher(s):
Giovanni Piantoni
Institution(s): Cortical Physiology Lab, Massachusets General Hospital, Harvard Medical School (USA) and Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final reports
1 article
Submitted papers
Language: eng
Author:
Piantoni, G.
Keywords:
Psychophysiology / Brain structure and function / Sleep and dreams

Reference code: PT/FB/BL-2012-220.05
Location: Arquivo PCA - Pasta 15/2012
Title:
Spatiotemporal evolution of the sleep spindle in human neocortex
Publication year: 2015
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=7b628b06-6369-42bc-a92b-b2cb9470ba61&cKey=99701e21-d75c-443d-813d-66d4b7079e0a&mKey=d0ff4555-8574-4fbb-b9d4-04eec8ba0c84
Abstract/Results: ABSTRACT:
Brain activity is the result of a dynamic interplay between cortical and thalamic neuronal populations and this often takes the shape of an oscillation. A characteristic phenomenon that is generated by the thalamocortical network during sleep is the spindle, a 0.5-2 s long burst of oscillations between 11 and 16 Hz. While animal and computational studies have highlighted the importance of the reciprocal connections between cortex and thalamus, the spatio-temporal properties of the spindle on the cortex remain largely unexplored. We here investigated the evolution of the spindle oscillations over large cortical areas, measured on the human neocortex. Spindles were described by their instantaneous amplitude and phase over neighboring electrodes. We collected recordings from NREM sleep stage 2, using electrocorticography in eight patients undergoing evaluation for intractable epilepsy. Electrodes covered large parts of one hemisphere and were spaced 1 cm apart. The research was approved by the local institutional review board and electrode placement was determined solely by clinical criteria. Based on the instantaneous amplitude in the spindle frequency band for each electrode, we computed the covariance on overlapping 1s long intervals of these time-series. We observed recurring patterns of spatio-temporal organization, which include focal, widespread and global spindling activities. Spindles were more likely to synchronize over multiple cortical areas if they included the lateral prefrontal cortex, a putative pivot of spindle activity. In addition, we observed a drastic phase reset at the beginning of the sleep spindle. We interpret this phase reset as the putative thalamic input to the cortical mantle. The spatial extent of this phenomenon was compatible with the two anatomically defined thalamocortical pathways: the spatially diffuse matrix pathway and the locally selective core pathway. These results highlight the importance of thalamocortical projections in shaping the spindle evolution and define the spatial extent of the functional influence of these projections. These findings will help elucidate the mechanisms underlying spindle generation and the functional role of thalamocortical loops, their possible role in sleep maintenance and memory, and their disruption in neurological disorders.
Accessibility: Document does not exist in file
Language:
eng
Author:
Piantoni, G.
Secondary author(s):
Halgren, E., Cash, S.
Document type:
Online abstract
Reference:
Piantoni, G., Halgren, E., & Cash, S. (2015, October). Spatiotemporal evolution of the sleep spindle in human neocortex. Paper presented at the Society for Neuroscience Meeting, Chicago. Abstract retrieved from http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=7b628b06-6369-42bc-a92b-b2cb9470ba61&cKey=99701e21-d75c-443d-813d-66d4b7079e0a&mKey=d0ff4555-8574-4fbb-b9d4-04eec8ba0c84
Indexed document: No
Keywords: Sleep / Synchrony / Electrophysiology

DocumentImpairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-030
Location: BF-GMS
Title:
030 - Exploring the neural basis of motivation
Duration: 2017-01 - 2020-03
Researcher(s):
Ana João Rodrigues, Nivaldo Vasconcelos, Carina Cunha, Bárbara Coimbra, Laura Silva, Patrícia Monteiro, Sónia Borges, Pedro Morgado
Institution(s): Life and Health Sciences Research Institute - ICVS, School of Health Sciences, University of Minho, Braga (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Rodrigues, A. J.
Secondary author(s):
Vasconcelos, N., Cunha, C., Coimbra, B., Silva, L., Monteiro, P., Borges, S., Morgado, P.
Keywords:
Reward / Reinforcement / Mesolimbic system / Behavior / Psychophysiology

Reference code: PT/FB/BL-2016-030.02
Location: BF-GMS
Title:
Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits
Publication year: 2017
URL:
https://elifesciences.org/articles/25843
Abstract/Results: ABSTRACT:
Ventral tegmental area (VTA) activity is critical for reward/reinforcement and is tightly modulated by the laterodorsal tegmentum (LDT). In utero exposure to glucocorticoids (iuGC) triggers prominent motivation deficits but nothing is known about the impact of this exposure in the LDT-VTA circuit. We show that iuGC-rats have long-lasting changes in cholinergic markers in the LDT, together with a decrease in LDT basal neuronal activity. Interestingly, upon LDT stimulation, iuGC animals present a decrease in the magnitude of excitation and an increase in VTA inhibition, as a result of a shift in the type of cells that respond to the stimulus. In agreement with LDT-VTA dysfunction, we show that iuGC animals present motivational deficits that are rescued by selective optogenetic activation of this pathway. Importantly, we also show that LDT-VTA optogenetic stimulation is reinforcing, and that iuGC animals are more susceptible to the reinforcing properties of LDT-VTA stimulation.
Accessibility: Document exists in file
Language:
eng
Author:
Coimbra, B.
Secondary author(s):
Soares-Cunha, C., Borges, S., Vasconcelos, N. A., Sousa, N., Rodrigues, A. J.
Document type:
Article
Reference:
Coimbra, B., Soares-Cunha, C., Borges, S., Vasconcelos, N. A., Sousa, N., & Rodrigues, A. J. (2017). Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits. eLife, 6: e25843. doi: 10.7554/eLife.25843
2-year Impact Factor: 7.616|2017
Times cited: 1|2020-03-31
Indexed document: Yes
Quartile: Q1
Keywords: Electrophysiology / Laterodorsal tegmentum / Motivation / Neuroscience / Optogenetics / Rat / Reward / Ventral tegmental area

Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits

Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits

File261 - Phenomenological experience and neurophysiological correlates of shamanic trance in healthy individuals

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-261
Location: BF-GMS
Title:
261 - Phenomenological experience and neurophysiological correlates of shamanic trance in healthy individuals
Researcher(s): Olivia Gosseries
Institution(s): GIGA research center, GIGA-Consciousness, University of Liège (Belgium)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Language: eng
Notes:
This project hasn't started yet
Author: Gosseries, O.
Keywords:
Trance / Phenomenology / Electrophysiology / Consciousness / Psychophysiology and Parapsychology

File269 - Electrophysiological and genetic factors associated with hypnosis, suggestibility and hypnotic phenomenology2019-06

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-269
Location: BF-GMS
Title:
269 - Electrophysiological and genetic factors associated with hypnosis, suggestibility and hypnotic phenomenology
Duration: 2019-06
Researcher(s):
William McGeown, Irving Kirsch, Giuliana Mazzoni, Rothwelle Tate, Annalena Venneri
Institution(s): School of Psychological Sciences and Health, University of Strathclyde, Glasgow (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Language: eng
Notes:
Ongoing project
Author: McGeown, W.
Secondary author(s):
Kirsch, I., Mazzoni, G., Tate, R., Venneri, A.
Keywords:
Hypnosis / Suggestibility / Electrophysiology / Genetics / Psychophysiology and Parapsychology

DocumentFinal report - Linking strawberries and politicians: The electrophysiology of the bimodal bilingual brain2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-226
Location: BF-GMS
Title:
226 - Linking strawberries and politicians: The electrophysiology of the bimodal bilingual brain
Duration: 2017-09 - 2020-01
Researcher(s):
Cristina Baus, Albert Costa, Marc Gimeno
Institution(s): Center for Brain and Cognition – CBC, Universitat Pompeu Fabra, Barcelona (Spain)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Costa, A.
Secondary author(s):
Baus, C., Gimeno, M.
Keywords:
Bilingualism / Language networks / Learning / Sign language / Psychophysiology

Reference code: PT/FB/BL-2016-226.01
Location: BF-GMS
Title:
Final report - Linking strawberries and politicians: The electrophysiology of the bimodal bilingual brain
Publication year: 2020
URL:
https://www.bial.com/media/3289/linking-strawberries-and-politicians.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
Bimodal bilinguals are those bilinguals fluent in two languages from two modalities, one signed and one spoken. Investigating language processing of those bilinguals is unique to understand how the brain is organized to represent and process two languages.
AIMS
The goal of the project “The Electrophysiology of the Bimodal Bilingual Brain” was to investigate the brain dynamics of bilingual language co-activation across modalities. Two major questions were addressed. How the learned properties of the signed language might alter the word organization of the spoken language? and, How the linguistic properties of the spoken modality influence learning of a signed language?
METHOD
Behavioral and electrophysiological measures were obtained in different language experiments to evaluate cross-language interactions in bimodal bilinguals. Behavioral performance (accuracy and reaction times) was obtained while participants performed comprehension (lexical decision task) or production tasks (picture naming task). Brain activity was also registered, allowing us to explore the brain chronometry of language processes involved in bimodal bilingualism.
RESULTS
We obtained evidence that the two languages of bimodal bilinguals interact during language production. Despite the two modalities do not share phonology, phonological cross-language effects were obtained, suggesting a lexical origin of cross-language activation. Additionally, our results revealed that to observe cross-linguistic interactions, a certain level of proficiency in the two languages is required.
CONCLUSIONS
The successful development of the project has allowed us to better understand the phenomenon of bilingual cross-language interactions across modalities.
Accessibility: Document exists in file
Language:
eng
Author:
Baus, C.
Document type:
Final report
Reference:
Baus, C. (2020). Final report - Linking strawberries and politicians: The electrophysiology of the bimodal bilingual brain.
Keywords: Bimodal bilingualism / Sign language / Electrophysiology / Brain chronometry

Final report - Linking strawberries and politicians: The electrophysiology of the bimodal bilingual brain

Final report - Linking strawberries and politicians: The electrophysiology of the bimodal bilingual brain

DocumentNeurophysiological correlates of a single session of prefrontal tDCS in patients with prolonged disorders of consciousness: A pilot double-blind randomized controlled study2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-56
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Neurophysiological correlates of a single session of prefrontal tDCS in patients with prolonged disorders of consciousness: A pilot double-blind randomized controlled study
Publication year: 2020
URL:
https://www.mdpi.com/2076-3425/10/7/469
Abstract/Results: ABSTRACT:
BACKGROUND
Transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (lDLPFC) was reported to promote the recovery of signs of consciousness in some patients in a minimally conscious state (MCS), but its electrophysiological effects on brain activity remain poorly understood.
OBJECTIVE
We aimed to assess behavioral (using the Coma Recovery Scale—Revised; CRS-R) and neurophysiological effects (using high density electroencephalography; hdEEG) of lDLPFC-tDCS in patients with prolonged disorders of consciousness (DOC).
METHODS
In a double-blind, sham-controlled, crossover design, one active and one sham tDCS (2 mA, 20 min) were delivered in a randomized order. Directly before and after tDCS, 10 min of hdEEG were recorded and the CRS-R was administered.
RESUTLS
Thirteen patients with severe brain injury were enrolled in the study. We found higher relative power at the group level after the active tDCS session in the alpha band in central regions and in the theta band over the frontal and posterior regions (uncorrected results). Higher weighted symbolic mutual information (wSMI) connectivity was found between left and right parietal regions, and higher fronto-parietal weighted phase lag index (wPLI) connectivity was found, both in the alpha band (uncorrected results). At the group level, no significant treatment effect was observed. Three patients showed behavioral improvement after the active session and one patient improved after the sham.
CONCLUSION
We provide preliminary indications that neurophysiological changes can be observed after a single session of tDCS in patients with prolonged DOC, although they are not necessarily paralleled with significant behavioral improvements.
Accessibility: Document exists in file
Language:
eng
Author:
Carrière, M.
Secondary author(s):
Mortaheb, S., Raimondo, F., Annen, J., Barra, A., Binda Fossati, M. C., Chatelle, C., Hermann, B., Martens, G., Di Perri, C., Laureys, S., Thibaut, A.
Document type:
Article
Reference:
Carrière, M., Mortaheb, S., Raimondo, F., Annen, J., Barra, A., Binda Fossati, M.C. ... Thibaut, A. (2020). Neurophysiological correlates of a single session of prefrontal tDCS in patients with prolonged disorders of consciousness: A pilot double-blind randomized controlled study. Brain Sciences, 10(7), 469. doi: 10.3390/brainsci10070469
2-year Impact Factor: 3.332|2019
Impact factor notes: Impact factor not available yet for 2020
Times cited: 0|2020-07-30
Indexed document: Yes
Quartile: Q2
Keywords: Minimally conscious state / Neuromodulation / Non-invasive brain stimulation / Electrophysiology / Brain injury

Neurophysiological correlates of a single session of prefrontal tDCS in patients with prolonged disorders of consciousness: A pilot double-blind randomized controlled study

Neurophysiological correlates of a single session of prefrontal tDCS in patients with prolonged disorders of consciousness: A pilot double-blind randomized controlled study

File295 - Peace of mind and emotion regulation: Survey-based, behavioural, and neuroscientific investigations2021-01

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-295
Location: BF-GMS
Title:
295 - Peace of mind and emotion regulation: Survey-based, behavioural, and neuroscientific investigations
Duration: 2021-01
Researcher(s):
Pilleriin Sikka
Institution(s): Department of Psychology and Speech-Language Pathology, University of Turku (Finland)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Language: eng
Notes:
Ongoing project
Author: Sikka, P.
Keywords:
Peace of mind / Emotion regulation / Electrophysiology / Attention / Psychophysiology

FileFinal report - Early life stress and social hierarchies: The role of cortico-striatal circuits2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-266
Location: BF-GMS
Title:
266 - Early life stress and social hierarchies: The role of cortico-striatal circuits
Duration: 2017-01 - 2021-01
Researcher(s):
João Peça, Joana Guedes, Ana Luísa Cardoso, Mohammed Hussien, Lara Franco, Mário Carvalho
Institution(s): Center for Neuroscience and Cell Biology, University of Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Peça, J.
Secondary author(s):
Guedes, J., Cardoso, A. L., Hussien, M., Franco, L., Carvalho, M.
Keywords:
Animal behavior / Social hierarchy / Stress / Optogenetics / Psychophysiology

Reference code: PT/FB/BL-2016-266.01
Location: BF-GMS
Title:
Final report - Early life stress and social hierarchies: The role of cortico-striatal circuits
Publication year: 2021
URL:
https://www.bial.com/media/3490/early-life-stress-and-social-hierarchies.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
Social behaviors are critical to the survival of most animal species. Gregarious behaviors strengthen social groups, reduce stress and increase fitness. However, the genetic and circuit basis of the regulation of social behaviors are not well understood.
AIMS
We aimed to dissect the influence of specific genes in social behaviors and their influence in neuronal circuits. One part of our project aimed at discovering, in an unbiased manner, which genetic elements could regulate social subordinance when animals experience early life stress. A second project investigated the role of GPRASP2, a gene known to influence sociability and autism in humans, in order to best understand its role in the brain.
METHOD
To dissect which genetic elements are responsible to induce social subordination following early life stress, we used a maternal deprivation protocol in C57BL6 mice. We also used a genetically engineered mouse model to understand the role of GPRASP2 in the regulation of social behaviors. For both approaches we employed a range of behavioral, histological and electrophysiological characterization.
RESULTS
This work sheds light on ethologically relevant processes with impact on biomedical sciences. Specifically, we found that the NPYergic system is important in the regulation of cortical circuits and the expression of social subordinate behavior. We also found that loss of GPRASP2 leads to altered social behaviors, deficits in social recognition and increased dominate behavior.
CONCLUSIONS
Our work identified novel genetic elements that play a significant role in the regulation of social behaviors.
Accessibility: Document exists in file
Language:
eng
Author:
Peça, J.
Secondary author(s):
Edfawy, M., Guedes, J., Franco, L., Cardoso, A. L., Carvalho, M.
Document type:
Final report
Reference:
Peça, J., Edfawy, M., Guedes, J., Franco, L., Cardoso, A. L., & Carvalho, M. (2021). Final report - Early life stress and social hierarchies: The role of cortico-striatal circuits
Keywords: Social behaviour / Social hierarchy / Animal model / Electrophysiology / Neuronal circuits

Final report - Early life stress and social hierarchies: The role of cortico-striatal circuits

Final report - Early life stress and social hierarchies: The role of cortico-striatal circuits