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Type Title Begin End
DocumentPK occurrences, epilepsy and repressed aggression: Analysis of Andrés Venier case2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1998
Location: Arquivo PCA - Pastas 1 a 11/1998
Title:
1998 Grants
Start date: 1999-01 - 2005-12
Dimension/support:
11 caixas de arquivo

Reference code: PT/FB/BL-1998-006
Location: Arquivo PCA - Pasta 1/1998
Title:
006 - A descriptive and correlational study of persons claiming spontaneous psi experiences
Duration: 1998-12 - 2001-12
Researcher(s):
Daniel Montanelli, Alejandro Parra
Institution(s): Instituto de Psicologia Paranormal, Buenos Aires (Argentina)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports (2 copies)
Final report
Magazine "NOTÍCIAS" of Buenos Aires
Language: eng
Author:
Gómez Montanelli, D.
Secondary author(s):
Parra, A.
Number of reproductions:
2
Keywords:
Parapsychology / Anomalous cognition/experiences / Spontaneous cases

Reference code: PT/FB/BL-1998-006.09
Location: Arquivo PCA - Pasta 1/1998
Title:
PK occurrences, epilepsy and repressed aggression: Analysis of Andrés Venier case
Publication year: 2004
Accessibility:
Document does not exist in file
Language:
eng
Author:
Parra, A.
Document type:
Article
Number of reproductions:
2
Reference:
Parra, A. (2004). PK occurrences, epilepsy and repressed aggression: Analysis of Andrés Venier case. Paranormal Review, 32, 23-27.
Indexed document: No
Keywords: Parapsychology / Spontaneous cases / Epilepsy

PK occurrences, epilepsy and repressed aggression: Analysis of Andrés Venier case

PK occurrences, epilepsy and repressed aggression: Analysis of Andrés Venier case

File025 - Crises pseudo-epiléticas: um estudo psicofisiológico1997-062002-04

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1996
Location: Arquivo PCA - Pastas 1 a 8/1996
Title:
1996 Grants
Start date: 1997-01 - 2005-05
Dimension/support:
8 caixas de arquivo

Reference code: PT/FB/BL-1996-025
Location: Arquivo PCA - Pasta 5/1996
Title:
025 - Crises pseudo-epiléticas: um estudo psicofisiológico
Duration: 1997-06 - 2002-04
Researcher(s):
Maria Sande e Lemos, António Martins, Ana Martins Farinha
Institution(s): Laboratório de EEG / Faculdade de Medicina de Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Language: por
Notes:
The project was not concluded and was closed in April 2002.
Author: Sande Lemos, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy

File054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2001-052003-03

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

DocumentFinal report - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.01
Location: Arquivo PCA - Pasta 3/2000
Title:
Final report - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2002
URL:
http://www.bial.com/imagem/Bolsa5400_19022014.pdf
Abstract/Results: RESULTS:
Behavioural interventions including biofeedback represent an alternative or adjunctive therapeutic axis in the management of drug refractory epilepsy. Our previous study suggested that the modulation of the peripheral state of arousal as indexed by the Galvanic Skin Response (GSR) had considerable influence on cortical excitability, indicating the possible use of biofeedback in controlling seizure activity. In the present study we investigated the effect of the GSR biofeedback training on seizure frequency in patients with treatment resistant epilepsy. Eighteen patients with drug refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n = 10) or to a sham control biofeedback group (n = 8). Patients received a total of 12 sessions over four weeks, representing either real GSR biofeedback training, where subjects were trained to control their GSR by receiving feedback of their own GSR change on the computer screen, or sham training, where the feedback was unrelated to the subjects’ GSR.
Biofeedback training significantly reduced patients’ seizure frequency in the active biofeedback group (p = 0.005), but not the control group (p>0.10). This was manifest as a significant between group differences in seizure reduction (p = 0.016). Furthermore there was a correlation between degree of patients’ improvement in biofeedback performance and reduction of seizure frequency (rho = 0.736, p = 0.001), confirming that the effect of biofeedback treatment was related to physiological change. Our findings demonstrate that a behavioural intervention, GSR biofeedback training, may be associated with a significant reduction in seizure frequency in drug refractory epilepsy, highlighting the potential therapeutic value of this method.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Fenwick, P., Trimble, M. R.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR) / Intervention

Relatório final - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Relatório final - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

DocumentChanges in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.06
Location: Arquivo PCA - Pasta 3/2000
Title:
Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy
Publication year: 2009
URL:
http://www.psychosomaticmedicine.org/content/71/1/84.full.pdf
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=19&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
OBJECTIVES:
To examine the immediate and sustained effects of volitional sympathetic modulation, using galvanic skin response (GSR) biofeedback training on cortical excitability in patients with drug-resistant epilepsy.
METHODS:
Ten patients undertook 12 sessions of GSR biofeedback training over 1 month, during which they were trained to increase sympathetic arousal, using GSR biofeedback. Contingent negative variation (CNV) (a slow cortical potential reflecting cortical arousal and excitability) and the related post imperative negative variation (PINV) were quantified before and after biofeedback treatment.
RESULTS:
A significant reduction in CNV amplitude was observed in both the short-term (within the first session, after 10 minutes of GSR biofeedback) and long-term (sustained after 12 training sessions). Specifically, the change in baseline CNV amplitude after the 12 training sessions correlated with a percentage reduction in seizure frequency. Furthermore, changes in baseline amplitude of the PINV also correlated with seizure reduction.
CONCLUSIONS:
Our findings demonstrate that behavioral enhancement of peripheral sympathetic tone (GSR) is associated with modulation of indices of cortical excitability. Moreover, GSR biofeedback training over repeated sessions was associated with a chronic baseline reduction in slow cortical potentials and concurrent therapeutic improvement.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D., Rothwell, J. C., Duncan, J. S., Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Critchley, H. D., Rothwell, J. C., Duncan, J. S., & Trimble, M. R. (2009). Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy. Psychosomatic Medicine, 71(1), 84-92. doi: 10.1097/PSY.0b013e31818f667c
2-year Impact Factor: 4.236|2009
Times cited: 23|2022-05-18
Indexed document: Yes
Quartile: Q1
Keywords: Biofeedback / Galvanic skin response (GSR) / Contingent negative variation (CNV) / Slow cortical potentials / Post imperative negative / Epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy

DocumentBehavioral treatment for epilepsy2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.07
Location: Arquivo PCA - Pasta 3/2000
Title:
Behavioral treatment for epilepsy
Publication year: 2007
Accessibility:
Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Document type:
Book chapter
Number of reproductions:
1
Reference:
Nagai, Y. (2007). Behavioral treatment for epilepsy. In K. J. Hollaway (Ed.), New research on epilepsy and behavior (pp. 279-294). New York, NY: Nova Publisher.
Indexed document: No
Keywords: Psychophysiology / Epilepsy

DocumentEffect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.09
Location: Arquivo PCA - Pasta 3/2000
Title:
Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2002
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/4%C2%BA_simposio.a110.html
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Fenwick, P., Goldstein, L., Lumsden, J., Trimble, M. R.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Nagai, Y., Fenwick, P., Goldstein, L., Lumsden, J., & Trimble, M. R. (2002). Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 4th Symposium of Fundaçăo Bial (p. 448). Porto: Fundaçăo Bial.
Indexed document: No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR)

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

DocumentEffect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.10
Location: Arquivo PCA - Pasta 3/2000
Title:
Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2004
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/5%C2%BA_simposio.a111.html
Abstract/Results: ABSTRACT:
Behavioural interventions including biofeedback represent an alternative or adjunctive therapeutic axis in the management of drug refractory epilepsy. Our previous study suggested that the modulation of the peripheral state of arousal as indexed by the Galvanic Skin Response (GSR) had considerable influence on cortical excitability, indicating the possible use of biofeedback in controlling seizure activity.
We investigated the effect of the GSR biofeedback training on seizure frequency in patients with treatment resistant epilepsy. Eighteen patients with drug refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n = 10) or to a sham control biofeedback group (n = 8). Patients received a total of 12 sessions over four weeks, representing either real GSR biofeedback training, where subjects were trained to decrease skin resistance using biofeedback, or sham training, where the feedback was unrelated to the subjects’ GSR. Biofeedback training significantly reduced patients’ seizure frequency in the active biofeedback group (p = 0.017), but not the control group (p>0.10). This was manifest as a significant between group difference in seizure reduction (p = 0.01). Our findings demonstrate that a behavioural intervention, GSR biofeedback training, may substantially reduce seizure frequency in drug refractory epilepsy, highlighting the potential therapeutic value of this method.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Nagai, Y., Trimble, M. R., Fenwick, P., Goldstein, L., & Lumsden, J. (2004). Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 5th Symposium of Fundaçăo Bial (pp. 306-307). Porto: Fundaçăo Bial.
Indexed document: No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR)

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

DocumentComparison of discrete-trial based SMR and SCP training and the interrelationship between SCP and SMR networks: Implications for brain-computer interfaces and neurofeedback2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-163
Location: Arquivo PCA - Pasta 7/2004
Title:
163 - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects
Duration: 2005-01 - 2006-04
Researcher(s):
Martijn Arns, Wytze van der Zwaag, Erica Heesen, Rien Breteler
Institution(s): Brain Resource Company B.V., Nijmegen (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report (2 copies)
Article
Master's thesis
Language: eng
Author:
Arns, M.
Secondary author(s):
Van der Zwaag, W., Heesen, E., Breteler, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning

Reference code: PT/FB/BL-2004-163.03
Location: Arquivo PCA - Pasta 7/2004
Title:
Comparison of discrete-trial based SMR and SCP training and the interrelationship between SCP and SMR networks: Implications for brain-computer interfaces and neurofeedback
Publication year: 2007
URL:
http://www.tandfonline.com/doi/abs/10.1080/10874200802162808?journalCode=wneu20#.UelbdWxdYq4
Abstract/Results: ABSTRACT:
BACKGROUND:
Operant conditioning of one's slow cortical potential (SCP) or sensorimotor rhythm (SMR) can be used to control epilepsy or to manipulate external devices, as applied in BCI (Brain-Computer Interface). A commonly accepted view that both SCP and SMR are reflections of central arousal suggests a functional relationship between SCP and SMR networks.
METHOD:
The operant conditioning of SCP or SMR was tested with a single electroencephalographic (EEG) channel wireless biofeedback system. A series of trainings taught 19 participants to control SCP or SMR over vertex during 20 neurofeedback sessions. Each session consisted of 96 trials to decrease cortical arousal (SCP positivity/SMR enhancement) and 64 trials to increase cortical arousal (SCP negativity/SMR suppression). In each trial, participants were required to exceed an individual threshold level of the feedback parameter relative to a 500-msec prefeedback baseline and to hold this level for 2 sec (SCP) or 0.5 sec (SMR) to obtain reinforcement.
RESULTS:
Ten of the 19 participants achieved control over their EEG. In the SCP-trained group, 4 of 9 participants increased the differentiation between their SCP responses on positivity-required versus negativity-required trials. SMR suppression and enhancement was achieved by 3 and 4 of the 10 SMR-trained participants. The SMR-trained responders did not show differentiation in their SMR responses, but did show a differentiation in their SCP response—while trained on SMR.
CONCLUSIONS:
The results showed the proposed method was successful to teach control of SCP or SMR. Bidirectional control was very difficult to achieve with the present SMR training procedure. SCP positivity and SMR enhancement were easier to learn. The results suggest that SMR training modulates excitability thresholds in the striatal-thalamocortical motor loop, whereas changes in the loop's excitability thresholds by SCP training do not affect the thalamic bursting that underlies the SMR.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Kleinnijenhuis, M.
Secondary author(s):
Arns, M., Spronk, D., Breteler, R.
Document type:
Article
Number of reproductions:
1
Reference:
Kleinnijenhuis, M., Arns, M., Spronk, D., & Breteler, R. (2007). Comparison of discrete-trial based SMR and SCP training and the interrelationship between SCP and SMR networks: Implications for brain-computer interfaces and neurofeedback. Journal of Neurotherapy, 11(4), 19-35. doi: 10.1080/10874200802162808
Indexed document: Yes
Keywords: Brain-Computer Interface (BCI) / Discrete training / Epilepsy / Neurofeedback / Sensorimotor rhythm / Slow cortical potentials

Comparison of discrete-trial based SMR and SCP training and the interrelationship between SCP and SMR networks: Implications for brain-computer interfaces and neurofeedback

Comparison of discrete-trial based SMR and SCP training and the interrelationship between SCP and SMR networks: Implications for brain-computer interfaces and neurofeedback

DocumentComparison of SMR and SCP training employing newly developed discrete-trial based biofeedback system2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-163
Location: Arquivo PCA - Pasta 7/2004
Title:
163 - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects
Duration: 2005-01 - 2006-04
Researcher(s):
Martijn Arns, Wytze van der Zwaag, Erica Heesen, Rien Breteler
Institution(s): Brain Resource Company B.V., Nijmegen (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report (2 copies)
Article
Master's thesis
Language: eng
Author:
Arns, M.
Secondary author(s):
Van der Zwaag, W., Heesen, E., Breteler, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning

Reference code: PT/FB/BL-2004-163.04
Location: Arquivo PCA - Pasta 7/2004
Title:
Comparison of SMR and SCP training employing newly developed discrete-trial based biofeedback system
Publication year: 2007
Abstract/Results:
ABSTRACT:
BACKGROUND:
Operant conditioning of one’s slow cortical potential (SCP) or sensorimotor rhythm (SMR) can be used to control epilepsy or to manipulate external devices, as applied in BCI (Brain-Computer Interface). To be practical, a BCI-system should use as less channels as possible. For this purpose, a wireless biofeedback system was developed that allows feedback of a single EEG-channel in discrete trials. The commonly accepted view that both the SCP and SMR are a reflection of central arousal suggests a functional
relationship between SCP and SMR networks.
METHODS:
A training was performed that aimed to teach 19 participants to control their SCP (n=9) or SMR (n=10) over vertex. Participants received 20 neurofeedback sessions, each comprising of 96 trials in which they had to decrease cortical arousal (SCP positivity/SMR enhancement) and 64 trials in which they had to increase cortical arousal (SCP negativity/SMR suppression). In a trial, participants were required to exceed an individual threshold level of the feedback parameter relative to a 500 ms pre-feedback baseline and hold this level for 2 seconds (SCP) or 0.5 seconds (SMR) in order to obtain reinforcement.
RESULTS:
Overall, 10 of the total of 19 participants achieved control over their EEG. In the SCP-trained group, 4 out of 9 participants were able to increase the differentiation between their SCP responses on positivityrequired vs. negativity-required trials over the course of the experiment. Improvements in control over the SMR in suppression-required and enhancement-required trials were acquired by respectively 3 and 4 of the 10 SMR-trained participants. These SMR-trained responders did not show differentiation between their
SMR responses in enhancement-required vs. suppression-required trials. Interestingly, the SMR responders did show a differentiation in their SCP response while trained on SMR.
CONCLUSIONS:
It can be concluded from this experiment that, with the proposed method, a number of the participants are able to acquire control over their SCP or SMR. For SMR, however, bidirectional control is very difficult to achieve with the present training procedure. Furthermore, SCP positivity and SMR enhancement are easier to learn compared to their counterparts. The observed SCP differentiation while training SMR and absence of equivalent SMR changes while training SCP suggest that SMR training modulates the central arousal system, whereas SCP training invokes local effects.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Kleinnijenhuis, M.
Document type:
Master's thesis
Number of reproductions:
1
Reference:
Kleinnijenhuis, M. (2007). Comparison of SMR and SCP training employing newly developed discrete-trial based biofeedback system (Unpublished master´s thesis). Netherlands: Radboud University Nijmegen.
Indexed document: No
Keywords: Brain-Computer Interface (BCI) / Epilepsy / Slow cortical potentials / Sensorimotor rhythm / Neurofeedback / Discrete training

Comparison of SMR and SCP training employing newly developed discrete-trial based biofeedback system

Comparison of SMR and SCP training employing newly developed discrete-trial based biofeedback system

File168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy2005-022007-07

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-168
Location: Arquivo PCA - Pasta 13/2004
Title:
168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Duration: 2005-02 - 2007-07
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Dániel Fabó
Institution(s): National Institute of Psychiatry and Neurology, Department of Neurology, Epilepsy Center, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Epilepsy / Sleep and dreams

DocumentFinal report - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-168
Location: Arquivo PCA - Pasta 13/2004
Title:
168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Duration: 2005-02 - 2007-07
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Dániel Fabó
Institution(s): National Institute of Psychiatry and Neurology, Department of Neurology, Epilepsy Center, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Epilepsy / Sleep and dreams

Reference code: PT/FB/BL-2004-168.01
Location: Arquivo PCA - Pasta 13/2004
Title:
Final report - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Publication year: 2007
URL:
http://www.bial.com/imagem/Bolsa%2016804.pdf
Abstract/Results: RESULTS:
Using the opportunity to record parahippocampal activity with foramen ovale electrodes in epilepsy patients we examined high-frequency activity and its relation to NREM sleep-slow oscillations and sleep spindles. Parahippocampal high-frequency activity was organized into bursts which were consistently associated with interictal epileptic spikes. Ripple density was higher during Non-REM than REM sleep (p<0.001). Ripple activity distinctly decreased time-locked to slow oscillation negative half-waves in the three patients without temporal structural alterations (p<0.001), whereas in the four patients with severe mesiotemporal structural alterations this coupling was obscure. Generally, in the patients ripple activity was increased before spindle peaks and distinctly decreased after the peak (p<0.001). Coordinated occurrence of hippocampal ripples, sleep spindles and slow oscillations have already been reported in animals yet the present results provide first evidence for such a temporal coupling in humans. Our findings are consistent with the notion of a hippocampo-to-neocortical information transfer during sleep that is linked to coordinate ripple and spindle activity, and that in the intact temporal lobe is synchronized to cortical slow oscillations.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Halász, P.
Secondary author(s):
Borbély, C., Fabó, D., Eross, L., Entz, L.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Epilepsy / Sleep / Hippocampus

Final report - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy

Final report - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy

DocumentTemporal coupling of parahippocampal ripples, sleep spindles and slow oscillations in humans2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-168
Location: Arquivo PCA - Pasta 13/2004
Title:
168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Duration: 2005-02 - 2007-07
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Dániel Fabó
Institution(s): National Institute of Psychiatry and Neurology, Department of Neurology, Epilepsy Center, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Epilepsy / Sleep and dreams

Reference code: PT/FB/BL-2004-168.02
Location: Arquivo PCA - Pasta 13/2004
Title:
Temporal coupling of parahippocampal ripples, sleep spindles and slow oscillations in humans
Publication year: 2007
URL:
http://www.ncbi.nlm.nih.gov/pubmed/17615093
Abstract/Results: ABSTRACT:
Ripples are high-frequency oscillation bursts in the mammalian hippocampus mainly present during Non-REM sleep. In rodents they occur in association with sharp waves and are grouped by the cortical slow oscillation such that, in parallel with sleep spindles, ripple activity is suppressed during the hyperpolarized down-state and enhanced during the depolarized up-state. The temporal coupling between slow oscillations, spindles and ripples has been suggested to serve a hippocampo-neocortical dialogue underlying memory consolidation during sleep. Here, we examined whether a similar coupling exists between these oscillatory phenomena in humans. In sleep recordings from seven epileptic patients, scalp-recorded slow oscillations and spindles as well as parahippocampal ripples recorded from foramen ovale electrodes were identified by automatic algorithms. Additionally, ripple and spindle root mean square activity was determined for relevant frequency bands. Ripple density was higher during Non-REM than REM sleep (P < 0.001). Ripple activity distinctly decreased time-locked to slow oscillation negative half-waves in the three patients without temporal structural alterations (P < 0.001), whereas in the four patients with severe mesiotemporal structural alterations this coupling was obscure. Generally, in the patients ripple activity was increased before spindle peaks and distinctly decreased after the peak (P < 0.001). Ripples were consistently associated with interictal spikes suggesting that spike-ripple complexes represent an epileptic transformation of sharp wave-ripple complexes in the epileptic hippocampus. Our findings are consistent with the notion of a hippocampo-to-neocortical information transfer during sleep that is linked to coordinate ripple and spindle activity, and that in the intact temporal lobe is synchronized to cortical slow oscillations.
Accessibility: Document does not exist in file
Language:
eng
Author:
Clemens, Z.
Secondary author(s):
Mölle, M., Eross, L., Barsi, P., Halász, P., Born, J.
Document type:
Article
Number of reproductions:
1
Reference:
Clemens, Z., Mölle, M., Eross, L., Barsi, P., Halász, P., & Born, J. (2007). Temporal coupling of parahippocampal ripples, sleep spindles and slow oscillations in humans. Brain, 130, 2868-2878. doi: 10.1093/brain/awm146
2-year Impact Factor: 8.568|2007
Times cited: 285|2022-05-19
Indexed document: Yes
Quartile: Q1
Keywords: Sleep / Hippocampus / Sharp-wave ripples / Slow oscillation / Epilepsy

Temporal coupling of parahippocampal ripples, sleep spindles and slow oscillations in humans

Temporal coupling of parahippocampal ripples, sleep spindles and slow oscillations in humans

DocumentIncreased parahippocampal delta activity characterises virtual navigation and REM sleep in humans2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-168
Location: Arquivo PCA - Pasta 13/2004
Title:
168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Duration: 2005-02 - 2007-07
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Dániel Fabó
Institution(s): National Institute of Psychiatry and Neurology, Department of Neurology, Epilepsy Center, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Epilepsy / Sleep and dreams

Reference code: PT/FB/BL-2004-168.04
Location: Arquivo PCA - Pasta 13/2004
Title:
Increased parahippocampal delta activity characterises virtual navigation and REM sleep in humans
Publication year: 2006
URL:
http://fens2006.neurosciences.asso.fr/abstracts/R1/A018_3.html
Abstract/Results: ABSTRACT:
Hippocampal theta or rhythmic slow activity (RSA) occurring during exploratory behaviours and rapid-eye-movement (REM) sleep is a characteristic and salient oscillatory rhythm in animals. By contrast, much controversy exists regarding the existence and the characteristics of this activity in humans. Some studies argued that human hippocampal theta activity appears in short and phasic bursts. On the contrary, earlier we showed that REM-dependent RSA recorded from the parahippocampal region is continuous like in animals but instead of the theta it falls in the delta frequency range. Here, we examined parahippocampal activity in 10 epilepsy patients implanted with foramen ovale electrodes while they were engaged in a virtual navigation task. Navigation was tested according to three conditions: an acquisition, a recall and a non-learning route-following condition. Recordings were also sampled from resting and REM sleep. For analyses, spectral power densities (SPD) were calculated for each 1 Hz wide frequency bin up to 10 Hz. During acquisition, SPD significantly increased in the 1 Hz, 2 Hz and the 3 Hz frequency bins when compared with resting. A similar but more robust increase was present in the 1 Hz, 2 Hz, 3 Hz, 4 Hz and 5 Hz frequency bins during REM sleep. Thus, increase was present in similar frequencies during the two conditions and these frequency ranges were below the traditional theta band. At the same time, other features of this activity, such as state-dependency and tonicity made this activity comparable to that seen in animals and suggest this activity to be the human analogue hippocampal theta in animals.
Accessibility: Document does not exist in file
Language:
eng
Author:
Clemens, Z.
Secondary author(s):
Borbély, C., Fabó, D., Halász, P.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Clemens, Z., Borbély, C., Fabó, D., & Halász P. (2006). Increased parahippocampal delta activity characterises virtual navigation and REM sleep in humans. FENS Abstr., vol.3, A018.3, 2006. Abstract retrieved from http://fens2006.neurosciences.asso.fr/abstracts/R1/A018_3.html
Indexed document: No
Keywords: Parahippocampal activity / Epilepsy / Virtual navigation / Sleep / Learning

DocumentTemporal coupling of parahippocampal ripples and sleep spindles in humans2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-168
Location: Arquivo PCA - Pasta 13/2004
Title:
168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Duration: 2005-02 - 2007-07
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Dániel Fabó
Institution(s): National Institute of Psychiatry and Neurology, Department of Neurology, Epilepsy Center, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Epilepsy / Sleep and dreams

Reference code: PT/FB/BL-2004-168.05
Location: Arquivo PCA - Pasta 13/2004
Title:
Temporal coupling of parahippocampal ripples and sleep spindles in humans
Publication year: 2006
URL:
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2869.2006.00540_57.x/pdf
Abstract/Results: ABSTRACT:
Ripples are high-frequency oscillation bursts in the mammalian hippocampus mainly present during NREM sleep. In rodents they occur in association with sharp waves and are known to be grouped by the cortical slow oscillation such that their occurrence is maximal during the surface positive, up states. Ripples were also shown to be temporally linked to sleep spindles. Importantly, coordinated spindleripple events have been suggested to provide a framework for information transfer between the hippocampus and the neocortex underlying memory consolidation. Our aim was to examine whether ripples recorded via parahippocampal electrocorticography are also temporally linked with slow oscillations and sleep spindles in epileptic
humans. Whole-night recordings from seven epilepsy patients implanted with foramen ovale (FO) electrodes were analysed. Negative half waves of the slow oscillation and sleep spindles recorded on the scalp as well as ripples in FO recordings were detected by an automatic algorithm. Ripple activity was also measured as root mean square (RMS) of the 80–140 Hz activity. Compared to baseline both ripple measures showed a significant increase time-locked to sleep spindles. In the three patients without temporal structural alterations ripple activity decreased time-locked to slow oscillation negative half waves. In the four other patients exhibiting hippocampal sclerosis, modulation of ripple activity by the negative half waves was much less clear. Ripples significantly increased during NREM sleep and were consistently associated with interictal epileptic spikes. This suggests that ripple/spike complexes represent an epileptic exaggeration of ripple/sharp wave complexes in the human epileptic hippocampus. Whether ripples are epileptically transformed or not, the present data provide first evidence for a temporal coupling between hippocampal ripples and neocortical spindles in humans.
Accessibility: Document does not exist in file
Language:
eng
Author:
Clemens, Z.
Secondary author(s):
Mölle, M., Eröss, L., Barsi, P., Halász, P., Born, J.
Document type:
Abstract
Number of reproductions:
1
Reference:
Clemens, Z., Molle, M., Eross, L., Barsi, P., Halasz, P., & Born, J. (2006). Temporal coupling of parahippocampal ripples and sleep spindles in humans. Journal of Sleep Research, 15(Suppl. 1), 242-242. doi: 10.1111/j.1365-2869.2006.00540_57.x
Indexed document: Yes
Keywords: Sleep / Hippocampus / Sharp-wave ripples / Epilepsy

Temporal coupling of parahippocampal ripples and sleep spindles in humans

Temporal coupling of parahippocampal ripples and sleep spindles in humans

DocumentEnhanced measured synchronization of unsynchronized sources: inspecting the physiological significance of synchronization analysis of whole brain electrophysiological recordings2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-033
Location: Arquivo PCA - Pasta 15/2004
Title:
033 - Dynamic brain patterns in neocortical areas during interpersonal transactions
Duration: 2005-01 - 2008-07
Researcher(s):
Richard Wennberg, Jose Luis Perez Velazquez
Institution(s): Krembil Neuroscience Centre, Toronto Western Hospital and The Hospital for Sick Children, University of Toronto (Canada)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Wennberg, R.
Secondary author(s):
Perez Velazquez, J. L.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Pain / Emotion / Empathy

Reference code: PT/FB/BL-2004-033.02
Location: Arquivo PCA - Pasta 15/2004
Title:
Enhanced measured synchronization of unsynchronized sources: inspecting the physiological significance of synchronization analysis of whole brain electrophysiological recordings
Publication year: 2007
URL:
http://academicjournals.org/journal/IJPS/article-abstract/937512C13308
Abstract/Results: ABSTRACT:
The analysis of synchronization, particularly phase locking, is being increasingly used in neuroscience to explore coordinated brain activity. The application of this methodology to magnetoencephalographic (MEG) and electroencephalographic (EEG) recordings would seem promising because these two recording techniques are not invasive and have great temporal resolution. However, current methods of synchronization analysis applied directly to raw MEG/EEG data may produce distorted results. In this work we introduce a model of brain activity based on random current dipoles that reproduces the main characteristics observed in measurements of real data synchronization, even when no synchronized activity is taking place among the sources. In particular we describe the effect of field superposition alone when secondary currents are excluded. It is also shown that the enhanced local synchronization, previously described in some studies of epileptic seizures, may result from the activity of only a few unsynchronized sources. We suggest three lines of research for further development and improvement to obtain more precise physiological interpretations of the synchronization analysis.
Accessibility: Document does not exist in file
Language:
eng
Author:
Garcia Dominguez, L.
Secondary author(s):
Wennberg, R., Perez Velazquez, J. L., Guevara Erra, R.
Document type:
Article
Number of reproductions:
1
Reference:
Garcia Dominguez, L., Wennberg, R., Perez Velazquez, J. L., & Guevara Erra, R. (2007). Enhanced measured synchronization of unsynchronized sources: inspecting the physiological significance of synchronization analysis of whole brain electrophysiological recordings. International Journal of Physical Sciences, 2(11), 305-317.
2-year Impact Factor: 0.554|2009
Impact factor notes: Impact factor computed since 2009
Times cited: 12|2022-05-19
Indexed document: Yes
Quartile: Q3
Keywords: Phase synchronization / Magnetoencephalography / Epilepsy

Enhanced measured synchronization of unsynchronized sources: inspecting the physiological significance of synchronization analysis of whole brain electrophysiological recordings

Enhanced measured synchronization of unsynchronized sources: inspecting the physiological significance of synchronization analysis of whole brain electrophysiological recordings

DocumentVariability of brain coordination dynamics in normal physiology and pathology2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-033
Location: Arquivo PCA - Pasta 15/2004
Title:
033 - Dynamic brain patterns in neocortical areas during interpersonal transactions
Duration: 2005-01 - 2008-07
Researcher(s):
Richard Wennberg, Jose Luis Perez Velazquez
Institution(s): Krembil Neuroscience Centre, Toronto Western Hospital and The Hospital for Sick Children, University of Toronto (Canada)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Wennberg, R.
Secondary author(s):
Perez Velazquez, J. L.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Pain / Emotion / Empathy

Reference code: PT/FB/BL-2004-033.05
Location: Arquivo PCA - Pasta 15/2004
Title:
Variability of brain coordination dynamics in normal physiology and pathology
Publication year: 2006
URL:
http://www.societyforchaostheory.org/insc/2006/FinalINSC2006Web.pdf
Abstract/Results: ABSTRACT:
Fluctuations in phase synchrony have been characteristically found in recordings from both normal physiological brains as well as pathological ones. These fluctuations, characteristically termed as noise, are
logistically difficult to separate from true neuronal activity largely due to current recording and analysis methods. We propose that phase synchrony fluctuations serve to maintain brain activity in an optimal state for cognitive processing, thereby not allowing it to fall into long-term periodic behavior. We compared fluctuations from controls to those found in patients with epilepsy or traumatic brain injuries (TBI). Phase synchronization analysis using the Hilbert Transform was performed on magnetoencephalography (MEG) and electroencephalography (EEG) recordings from controls and patients. In the MEG study, 4 epileptic patients and 4 controls were tested. A total of 14 head-injured children and 2 controls were analyzed using scalp EEG, after performing a Laplacian Derivation. Results - Phase-locking patterns between brain areas were found to display fluctuations at different scales. Both epileptiform activity and TBI had relatively low levels of fluctuations in phase synchrony. This may contribute to the generation of synchronized states seen in patients with these brain disorders. Conclusions and Implications. Determination of phase-locking patterns and their variability in brain recordings reveals characteristics of the pathologies with which they are associated. While there is no clear distinction between noise and highdimensional dynamics, we propose that the examination of neuronal fluctuations at different levels will provide important insights into our understanding of the relationship between brain and behavior.
Accessibility: Document does not exist in file
Language:
eng
Author:
Belkas, J.
Secondary author(s):
Guevara Erra, R., García Dominguez, L., Nenadovic, V., Wennberg, R., Hutchison, J., Perez Velazquez, J. L.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Belkas, J., Guevara Erra, R., García Dominguez, L., Nenadovic, V., Wennberg, R., Hutchison, J., & Perez Velazquez, J. L. (2006). Variability of brain coordination dynamics in normal physiology and pathology. In Conference book of the 2nd International Nonlinear Science Conference, Heraklion, Greece (p. 50).
Indexed document: No
Keywords: Psychophysiology / Synchrony fluctuations / Epilepsy

Variability of brain coordination dynamics in normal physiology and pathology

Variability of brain coordination dynamics in normal physiology and pathology

DocumentCrises pseudo-epilépticas: um estudo psicofisiológico1998

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1996
Location: Arquivo PCA - Pastas 1 a 8/1996
Title:
1996 Grants
Start date: 1997-01 - 2005-05
Dimension/support:
8 caixas de arquivo

Reference code: PT/FB/BL-1996-025
Location: Arquivo PCA - Pasta 5/1996
Title:
025 - Crises pseudo-epiléticas: um estudo psicofisiológico
Duration: 1997-06 - 2002-04
Researcher(s):
Maria Sande e Lemos, António Martins, Ana Martins Farinha
Institution(s): Laboratório de EEG / Faculdade de Medicina de Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Language: por
Notes:
The project was not concluded and was closed in April 2002.
Author: Sande Lemos, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy

Reference code: PT/FB/BL-1996-025.01
Location: Arquivo PCA - Pasta 5/1996
Title:
Crises pseudo-epilépticas: um estudo psicofisiológico
Publication year: 1998
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/2%C2%BA_simposio.a108.html
Accessibility: Document does not exist in file
Language:
por
Author:
Sande Lemos, M.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Sande Lemos, M. (1998). Crises pseudo-epilépticas: um estudo psicofisiológico. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 2nd Symposium of Fundaçăo Bial (pp. 227-228). Porto: Fundaçăo Bial.
Indexed document: No
Keywords: Psychophysiology / Epilepsy / Pseudoepilepsy

Novo ficheiro

Novo ficheiro

File016 - Perceptual memory in the human visual system2006-022010-04

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-016
Location: Arquivo PCA - Pasta 24/2004
Title:
016 - Perceptual memory in the human visual system
Duration: 2006-02 - 2010-04
Researcher(s):
Patrícia Margarida Piedade Figueiredo, Mafalda Cavalheiro Gomes Moreira Mendes, Maria Fátima Loureiro da Silva, Joăo Abel Loureiro Marques Xavier, Carlos Gomes
Institution(s): Instituto Biofísico para a Investigaçăo em Luz e Imagem (IBILI), Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Abstracts and posters
Informed consent forms
Review of the final report
Language: eng
Author:
Figueiredo, P.
Secondary author(s):
Mendes, M., Silva, M. F., Xavier, J., Gomes, C.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Cognitive processes / Memory / Learning / Perception / Biopsychological problems / Diseases/Injuries / Epilepsy

DocumentFinal report - Perceptual memory in the human visual system2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-016
Location: Arquivo PCA - Pasta 24/2004
Title:
016 - Perceptual memory in the human visual system
Duration: 2006-02 - 2010-04
Researcher(s):
Patrícia Margarida Piedade Figueiredo, Mafalda Cavalheiro Gomes Moreira Mendes, Maria Fátima Loureiro da Silva, Joăo Abel Loureiro Marques Xavier, Carlos Gomes
Institution(s): Instituto Biofísico para a Investigaçăo em Luz e Imagem (IBILI), Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Abstracts and posters
Informed consent forms
Review of the final report
Language: eng
Author:
Figueiredo, P.
Secondary author(s):
Mendes, M., Silva, M. F., Xavier, J., Gomes, C.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Cognitive processes / Memory / Learning / Perception / Biopsychological problems / Diseases/Injuries / Epilepsy

Reference code: PT/FB/BL-2004-016.01
Location: Arquivo PCA - Pasta 24/2004
Title:
Final report - Perceptual memory in the human visual system
Publication year: 2010
URL:
http://www.bial.com/imagem/Bolsa1604.pdf
Abstract/Results: RESULTS:
In this Project, we have investigated memory mechanisms in the human visual system, by employing a combination of psychophysics and functional magnetic resonance imaging (fMRI) methodologies to identify the neural correlates of different types of learning processes. For this purpose, we implemented and optimized a number of fMRI visual mapping paradigms in order to identify the visual brain areas of interest.
We first observed the adaptive functional reorganization of visual memory in a population of temporal lobe epilepsy patients with right unilateral hippocampal sclerosis. We used fMRI to measure brain activity changes during the episodic encoding of abstract line drawings and found that the patients engaged the left hippocampus more than controls and that the level of engagement was correlated with their memory recognition scores. These finds suggested functional reorganization of visual memory with an adaptive role, as a consequence of prolonged disease. We also found that familiar items activated visual cortical areas more than novel items, suggesting a reinstatement of visual information as a consequence of learning.
In a second study, we implemented a visual learning paradigm whereby subjects performed a face discrimination task on faces presented in multiple orientations, in order to investigate the hypothesis that the human visual system contains specialized processing mechanisms that are more engaged by upright faces than by inverted faces or non-face objects, as a result of extensive practice with upright faces. Our psychophysics experiments showed that participants gave more errors and were slower in their responses as faces were rotated away from 0ş. In addition, performance was improved when participants underwent periods of training, both for trained and untrained orientations. Consistently with the expertise hypothesis, we also found a parametric modulation of fMRI activity in specialized visual brain areas, according to the quadratic behavioural effect of face orientation.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Figueiredo, P.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Visual memory / Epilepsy / Memory recognition / Perception / Face discrimination

Final report - Perceptual memory in the human visual system

Final report - Perceptual memory in the human visual system