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BIAL Foundation
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DocumentI keep a close watch on this heart of mine: increased interoception in insomnia2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-252
Location: SEC PCA 252/12
Title:
252 - Sleep state misperception mispercieved
Duration: 2014-06 - 2017-01
Researcher(s):
Eus J. W. Van Someren, J. Ramautar
Institution(s): Netherlands Institute for Neuroscience, Dept. Sleep & Cognition, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress reports
Final reports
2 Articles
Language: eng
Author:
Van Someren, E.
Secondary author(s):
Ramautar, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Sleep and dreams / Biopsychological problems / Mental health / Sleep disorders / Brain structure and function / Cognitive processes / Memory / Consciousness

Reference code: PT/FB/BL-2012-252.03
Location: SEC PCA 252/12
Title:
I keep a close watch on this heart of mine: increased interoception in insomnia
Publication year: 2016
URL:
Visitante: / https://www.ncbi.nlm.nih.gov/pubmed/27634787
Abstract/Results: ABSTRACT:
STUDY OBJECTIVES:
Whereas both insomnia and altered interoception are core symptoms in affective disorders, their neural mechanisms remain insufficiently understood and have not previously been linked. Insomnia Disorder (ID) is characterized by sensory hypersensitivity during wakefulness and sleep. Previous studies on sensory processing in ID addressed external stimuli only, but not interoception. Interoceptive sensitivity can be studied quantitatively by measuring the cerebral cortical response to one's heartbeat (heartbeat-evoked potential, HEP). We here investigated whether insomnia is associated with increased interoceptive sensitivity as indexed by the HEP amplitude.
METHODS:
Sixty-four participants aged 21-70 years were recruited through www.sleepregistry.nl including 32 people suffering from ID and 32 age- and sex-matched controls without sleep complaints. HEPs were obtained from resting-state high-density electroencephalography (HD-EEG) recorded during evening wakeful rest in eyes-open (EO) and eyes-closed (EC) conditions of 5-minute duration each. Significance of group differences in HEP amplitude and their topographical distribution over the scalp were assessed by means of cluster-based permutation tests.
RESULTS:
In particular during EC, and to a lesser extent during EO, people with ID had a larger amplitude late HEP component than controls at frontal electrodes 376-500 ms after the R-wave peak. Source localization suggested increased neural activity time-locked to heartbeats in people with ID mainly in anterior cingulate/medial frontal cortices.
CONCLUSIONS:
People with insomnia show insufficient adaptation of their brain responses to the ever-present heartbeats. Abnormalities in the neural circuits involved in interoceptive awareness including the salience network may be of key importance to the pathophysiology of insomnia.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Ramautar, J., Colombo, M., Stoffers, D., Gomez-Herrero, G., van der Meijden, W. P., Te Lindert, B. H., van der Werf, Y., Van Someren, E.
Document type:
Article
Number of reproductions:
1
Percentiles:
91.42|2.16
Reference:
Wei, Y., Ramautar, J., Colombo, M., Stoffers, D., Gomez-Herrero, G., van der Meijden, W. P., Te Lindert, B. H., van der Werf, Y., & Van Someren, E. (2016). I keep a close watch on this heart of mine: increased interoception in insomnia. Sleep, 39(12), 2113-2124. https://doi.org/10.5665/sleep.6308
Impact Factor: 4.923|2016
Times cited: 70|2026-02-06
Indexed document: Yes
Quartile: Q1
Keywords: Insomnia disorder / Interoception / Heartbeat-evoked potential / Event-related potential / High-density EEG / Hyperarousal / Resting state / Salience network
DocumentMeditation and attention: A controlled study on long-termmeditators in behavioral performance and event-related potentials of attentional control2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-149
Location: Arquivo PCA - Pasta 13/2008
Title:
149 - A closer look at meditation: Challenging the attentional network on different types of meditative procedures
Duration: 2010-04 - 2011-09
Researcher(s):
Stefan Schmidt, Harald Walach, Thilo Hinterberger, Matthias Braeunig, Dr. Jose Raul Naranjo, Kathrin Simshäuser
Institution(s): Center for Mindfulness, Meditation and Neuroscience Research, Instit. of Environmental Health Sciences, Univ. Medical Center Freiburg (Germany)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Schmidt, S.
Secondary author(s):
Walach, H., Hinterberger, T., Braeunig, M., Naranjo, J. R., Simshäuser, K.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Cognitive processes / Attention / Brain structure and function / Altered states of consciousness / Meditation

Reference code: PT/FB/BL-2008-149.09
Location: Arquivo PCA - Pasta 13/2008
Title:
Meditation and attention: A controlled study on long-termmeditators in behavioral performance and event-related potentials of attentional control
Publication year: 2015
URL:
Visitante: / http://www.sciencedirect.com/science/article/pii/S0167876015300519
Abstract/Results: ABSTRACT:
Meditation practice involves attention regulation, and thus is thought to facilitate attention control mechanisms. Studies on meditation techniques using a behavioral measurement of the Attention Network Test (ANT) have shown enhanced attention control, but neural features remain unknown. In the present study, event-related potentials (ERPs) and behavioral data from twenty long-term meditators were examined, compared to data obtained from twenty matched controls. Results showed that meditators made fewer error responses than controls, especially during the incongruent target condition, suggesting higher accuracy in executive attention control among meditators. The P3 amplitude in the parietal area remained constant in the congruent and incongruent target conditions among meditators, indicating a higher parietal P3 amplitude during the incongruent target condition relative to matched controls. The findings that meditators exhibited fewer error responses on the ANT and a lack of parietal P3 modulation irrespective of reaction time are discussed in the context of attentional resource allocation.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Jo, H. -G.
Secondary author(s):
Schmidt, S., Inacker, E., Markowiak, M., Hinterberger, T.
Document type:
Article
Number of reproductions:
1
Percentiles:
81.22|1.29
Reference:
Jo, H. -G., Schmidt, S., Inacker, E., Markowiak, M., & Hinterberger, T. (2015). Meditation and attention: A controlled study on long-termmeditators in behavioral performance and event-related potentials of attentional control. International Journal of Psychophysiology, 99, 33-39. https://doi.org/10.1016/j.ijpsycho.2015.11.016
Impact Factor: 2.596|2015
Times cited: 36|2026-02-06
Indexed document: Yes
Quartile: Q2
Keywords: Attention Network Test / Electroencephalogram / Event-related potential / P3 / Meditation
DocumentInhibitory control impairment on somatosensory gating due to aging: An event-related potential study2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-385
Location: BF-GMS
Title:
385 - Effects of neurofeedback on functional connectivity and EEG power density
Duration: 2015-03 - 2019-06
Researcher(s):
Pedro Jose Montoya Jimenez, Beatriz Rey Solaz, Inmaculada Riquelme, Miguel Angel Munoz Garcia, Niels Birbaumer
Institution(s): University of Balearic Islands - Research Institute on Health Sciences, Palma (Spain)
Contents: Contents:
Application form
Correspondence
Progress reports
Final report
Articles
Language: eng
Author:
Montoya, P.
Secondary author(s):
Solaz, B., Riquelme, I., Garcia, M., Birbaumer, N.
Number of reproductions:
1
Keywords:
Real-time fMRI neurofeedback / Pain / Insula / Anterior cingulate cortex / Psychophysiology

Reference code: PT/FB/BL-2014-385.03
Location: BF-GMS
Title:
Inhibitory control impairment on somatosensory gating due to aging: An event-related potential study
Publication year: 2018
URL:
Visitante: / https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052091/
Abstract/Results: ABSTRACT:
The capacity to suppress irrelevant incoming input, termed sensory gating, is one of the most investigated inhibitory processes associated with cognitive impairments due to aging. The aim of this study was to examine the influence of aging on sensory gating by using somatosensory event-related potentials (ERPs) elicited by repetitive non-painful tactile stimulation (paired-pulsed task). Somatosensory ERPs were recorded in 20 healthy young adults and 20 healthy older adults while they received two identical pneumatic stimuli (S1 and S2) of 100 ms duration with an inter-stimulus interval of 550 ± 50 ms on both forefingers. The difference between the somatosensory ERPs amplitude elicited by S1 and S2 was computed as a sensory gating measure. The amplitude and the latency of P50, N100 and late positive complex (LPC) were analyzed as well as the source generators of the gating effect. Reduced sensory gating was found in older individuals for N100 at frontal and centro-parietal electrodes and for LPC at fronto-central electrodes. Source localization analyses also revealed a reduced current density during gating effect in the older group in frontal areas in N100 and LPC. Moreover, older individuals showed delayed latencies in N100. No significant gating effect differences were found between groups in P50. These findings suggest an age-related slowing of processing speed and a reduced efficiency of inhibitory mechanisms in response to repetitive somatosensory information during stimulus evaluation, and a preservation of processing speed and inhibitory control during early stimulus coding in aging.
Accessibility: Document exists in file
Language:
eng
Author:
Terrasa, J. L.
Secondary author(s):
Montoya, P., González-Roldán, A. M., Sitges, C.
Document type:
Article
Number of reproductions:
1
Percentiles:
61.62|0.70
Reference:
Terrasa, J. L., Montoya, P., González-Roldán, A. M., & Sitges, C. (2018). Inhibitory control impairment on somatosensory gating due to aging: An event-related potential study. Frontiers in Human Neuroscience, 12: 280. https://doi.org/10.3389/fnhum.2018.00280
Impact Factor: 2.870|2018
Times cited: 17|2026-02-11
Indexed document: Yes
Quartile: Q2
Keywords: Aging / Event-related potential / Inhibitory deficit hypothesis / Paired-pulse task / Somatosensory gating / Source localization

Inhibitory control impairment on somatosensory gating due to aging: An event-related potential study

Inhibitory control impairment on somatosensory gating due to aging: An event-related potential study
DocumentFinal report - Age-related changes in motor-cognitive dual-tasking: An electrophysiological investigation of interference at the level of sub-task elements2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: Visitante: / http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-086
Location: BF-GMS
Title:
086 - Age-related changes in motor-cognitive dual-tasking: An electrophysiological investigation of interference at the level of sub-task elements
Duration: 2021-10 - 2024-05
Researcher(s):
Subhobrata Mitra, Christina Howard
Institution(s): Psychology Department, Nottingham Trent University (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Mitra, S.
Secondary author(s):
Howard, C.
Number of reproductions:
1
Keywords:
Dual tasking / Ageing / Motor control / Cognition / Psychophysiology

Reference code: PT/FB/BL-2020-086.01
Location: BF-GMS
Title:
Final report - Age-related changes in motor-cognitive dual-tasking: An electrophysiological investigation of interference at the level of sub-task elements
Publication year: 2024
Abstract/Results:
Abstract:
Continuous sensorimotor coordinations (CSCs) such as driving, walking, using control interfaces, or maintaining the body’s balance are often performed alongside cognitive tasks involving attention and executive function (EF). Such dual tasks can mutually interfere, particularly in older adults, but the timing, direction and reciprocity of interference are not yet understood at the level of task components. This project’s two experiments compared the chronometry of dual task interference between a visual oddball task and a continuous visuomanual tracking task in young and older adults. The oddball task’s components and their cortical resourcing were identified using EEG, and tracking deviations reflected perturbations to state monitoring in the CSC task. Despite instructions to give equal priority to both tasks, older participants tried to maintain resourcing of the oddball task whereas young participants reduced resourcing to accommodate the demands of the tracking task. As a result, older adults’ tracking deviation lasted longer. The older group’s tendency to reserve resources for oddball operations persisted even when increased EF load in the second experiment reduced their oddball task resourcing and performance and increased both groups’ tracking deviations. Notably, this resource reservation tendency was anticipatory in nature as it was detectable earlier in the trial timeline than the EF loading component itself. These detailed chronometric results clarify that age-related amplification of CSC-cognitive interference is largely due to greater inflexibility in task prioritization. Prioritization of the cognitive task over the CSC in this type of dual tasking may have safety implications in everyday task settings.
Accessibility: Document exists in file
Language:
eng
Author:
Mitra, S.
Document type:
Final report
Number of reproductions:
1
Reference:
Mitra, S. (2024). Final report - Age-related changes in motor-cognitive dual-tasking: An electrophysiological investigation of interference at the level of sub-task elements.
Indexed document: No
Keywords: Dual tasking / Sensorimotor coordination / Event-related potential / Event-related potential / Executive function / Electrophysiology

Final report - Age-related changes in motor-cognitive dual-tasking: An electrophysiological investigation of interference at the level of sub-task element

Final report - Age-related changes in motor-cognitive dual-tasking: An electrophysiological investigation of interference at the level of sub-task element