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BIAL Foundation
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DE:"FDG-PET"
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DocumentBCI performance and brain metabolism profile in severely brain-injured patients without response to command at bedside2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-13
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
BCI performance and brain metabolism profile in severely brain-injured patients without response to command at bedside
Publication year: 2018
URL:
https://www.frontiersin.org/articles/10.3389/fnins.2018.00370/full
Abstract/Results: ABSTRACT:
Detection and interpretation of signs of "covert command following" in patients with disorders of consciousness (DOC) remains a challenge for clinicians. In this study, we used a tactile P3-based BCI in 12 patients without behavioral command following, attempting to establish "covert command following." These results were then confronted to cerebral metabolism preservation as measured with glucose PET (FDG-PET). One patient showed "covert command following" (i.e., above-threshold BCI performance) during the active tactile paradigm. This patient also showed a higher cerebral glucose metabolism within the language network (presumably required for command following) when compared with the other patients without "covert command-following" but having a cerebral glucose metabolism indicative of minimally conscious state. Our results suggest that the P3-based BCI might probe "covert command following" in patients without behavioral response to command and therefore could be a valuable addition in the clinical assessment of patients with DOC.
Accessibility: Document exists in file
Language:
eng
Author:
Annen, J.
Secondary author(s):
Blandiaux, S., Lejeune, N., Bahri, M. A., Thibaut, A., Cho, W., Guger, C., Chatelle, C., Laureys, S.
Document type:
Article
Number of reproductions:
3
Reference:
Annen, J., Blandiaux, S., Lejeune, N., Bahri, M. A., Thibaut, A., Cho, W., Guger, C., Chatelle, C., & Laureys, S. (2018). BCI performance and brain metabolism profile in severely brain-injured patients without response to command at bedside. Frontiers in Neuroscience, 12, 370. https://doi.org/10.3389/fnins.2018.00370
2-year Impact Factor: 3.648|2018
Times cited: 18|2025-09-17
Indexed document: Yes
Quartile: Q2
Keywords: FDG-PET / P3 / Brain computer interface / Consciousness / Covert command following / Disorders of consciousness

BCI performance and brain metabolism profile in severely brain-injured patients 2 without response to command at bedside

BCI performance and brain metabolism profile in severely brain-injured patients 2 without response to command at bedside