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BIAL Foundation
DE:"Fronto-temporal interactions"
Selection Description
Type Title Begin End
DocumentFinal report - Interaction of medial and lateral temporal lobe in memory expression: insights from patient and fMRI data2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
BIAL Foundation Archive
Start date: 1994
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-089
Location: Arquivo PCA - Pasta 11/2012
089 - Interaction of medial and lateral temporal lobe in memory expression: insights from patient and fMRI data
Duration: 2013-04 - 2016-01
Ana Luísa Nunes Raposo, José Frederico Henzler Ferreira Marques, José Guilherme Cortez Pimentel
Institution(s): Faculdade de Psicologia, Universidade de Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Progress reports
Final report
Language: eng
Raposo, A.
Secondary author(s):
Marques, J., Pimentel, J.
Number of reproductions:
Psychophysiology / Cognitive processes / Memory / Biopsychological problems / Diseases/Injuries / Epilepsy / Brain structure and function

Reference code: PT/FB/BL-2012-089.01
Location: Arquivo PCA - Pasta 11/2012
Final report - Interaction of medial and lateral temporal lobe in memory expression: insights from patient and fMRI data
Publication year: 2015
Abstract/Results: ABSTRACT:
While a dog is a good example of a mammal, a bat is less so. Concept typicality, i.e., the degree to which a concept belongs to a category, has for long been known as critical to structuring conceptual knowledge. Recently, it has also been recognized as important in episodic memory, although the way this semantic dimension shapes episodic retrieval is still unclear.
We explored the interaction between semantic and episodic memory, in particular how concept typicality, a key dimension in semantic organization, modulates the neurocognitive bases of episodic retrieval.
A behavioural and an fMRI study with healthy young adults explored concept typicality effects on both semantic and episodic decisions. In a semantic task, participants saw a category (e.g., mammal) followed by typical (e.g., dog) or atypical (e.g., bat) item and decided if the item belonged to the category. In a subsequent memory retrieval task, previously seen items and new ones were shown and participants indicated if the item was old or new.
Participants were faster and more accurate to categorize typical than atypical items. Interestingly, the memory retrieval task revealed the opposite effect with better retrieval of atypical items. At a neural level, retrieval of atypical items (relative to new ones) involved a large network including lateral temporal cortices bilaterally, left lateral and medial prefrontal, and bilateral angular gyrus. Conversely, retrieval of typical items only showed posterior cingulate and superior parietal activation.
During retrieval of atypical items, the lateral temporal cortex, critical in the storage of semantic features, interplays with lateral and medial prefrontal areas, involved in semantic elaboration and monitoring. Atypical items carry distinctive features (e.g., a bat is a flying mammal) that are more related to the memory decision. These distinctive events induce greater semantic elaboration, via fronto-temporal interactions, which promote episodic retrieval.
Accessibility: Document exists in file
By permission
Raposo, A.
Document type:
Final report
Number of reproductions:
Indexed document:
Keywords: Concept typicality / Semantic memory / Episodic retrieval / Fronto-temporal interactions