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BIAL Foundation
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DocumentAlterations of the default mode network connectivity in obsessive-compulsive personality disorder: A pilot study2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-087
Location: Arquivo PCA - Pasta 24/2012
Title:
087 - Neurobiological correlates of empathy in couples: A study of central and peripheral measures
Duration: 2013-05 - 2017/07
Researcher(s):
Joana Fernandes Pereira Coutinho, Cledna Patricia de Oliveira Silva, Jean Decety, Kristin Perrone McGovern, Óscar Filipe Coelho Neves Gonçalves, Vânia Andrea Sousa Gonçalves Moreira de Lima
Institution(s): Centro de Investigação em Psicologia, Escola de Psicologia, Universidade do Minho (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
2 Articles (1 published and 1 submitted)
Language: eng
Author:
Coutinho, J.
Secondary author(s):
Silva, C. P., Decety, J., McGovern, K., Gonçalves, O., Lima, V.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Empathy / Affective and social behavior / Conjugality / Brain structure and function / Intervention

Reference code: PT/FB/BL-2012-087.21
Location: Arquivo PCA - Pasta 24/2012
Title:
Alterations of the default mode network connectivity in obsessive-compulsive personality disorder: A pilot study
Publication year: 2016
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0925492716301056?via%3Dihub
Abstract/Results: ABSTRACT:
Obsessive-compulsive personality (OCPD) disorder is characterized by a pattern of excessive self-control, perfectionism and behavioral and cognitive rigidity. Despite the fact that OCPD is the most common personality disorder in the general population, published studies looking at the brain correlates of this disorder are practically nonexistent. The main goal of this study was to analyze the presence of brain alterations in OCPD when compared to healthy controls, specifically at the level of the Default Mode Network (DMN). The DMN is a well-established resting state network which was found to be associated with psychological processes that may play a key role in OCPD (e.g., self-awareness, episodic future thinking and mental simulation). Ten individuals diagnosed with OCPD and ten healthy controls underwent a clinical assessment interview and a resting-state functional magnetic resonance imaging (fMRI) acquisition. The results show that OCPD patients presented an increased functional connectivity in the precuneus (i.e., a posterior node of the DMN), known to be involved in the retrieval manipulation of past events in order to solve current problems and develop plans for the future. These results suggest that this key node of the DMN may play an important role in the pathophysiology of OCPD. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Coutinho, J.
Secondary author(s):
Goncalves, O. F., Soares, J. M., Marques, P., Sampaio, A.
Document type:
Article
Number of reproductions:
1
Reference:
Coutinho, J., Goncalves, O. F., Soares, J. M., Marques, P., & Sampaio, A. (2016). Alterations of the default mode network connectivity in obsessive-compulsive personality disorder: A pilot study. Psychiatry Research: Neuroimaging, 256, 1-7. https://doi.org/10.1016/j.pscychresns.2016.08.007
2-year Impact Factor: 1.878|2016
Times cited: 15|2025-09-16
Indexed document: Yes
Quartile: Q3
Keywords: Obsessive-compulsive personality disorder / Neuroimaging; / Functional MRI / Default-mode network / Functional connectivity
DocumentNeurophysiological biomarkers of persistent post-concussive symptoms: A scoping review2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-92
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Neurophysiological biomarkers of persistent post-concussive symptoms: A scoping review
Publication year: 2021
URL:
https://www.frontiersin.org/articles/10.3389/fneur.2021.687197/full
Abstract/Results: ABSTRACT:
Background and Objectives: Persistent post-concussive symptoms (PCS) consist of neurologic and psychological complaints persisting after a mild traumatic brain injury (mTBI). It affects up to 50% of mTBI patients, may cause long-term disability, and reduce patients' quality of life. The aim of this review was to examine the possible use of different neuroimaging modalities in PCS.
Methods: Articles from Pubmed database were screened to extract studies that investigated the relationship between any neuroimaging features and symptoms of PCS. Descriptive statistics were applied to report the results.
Results: A total of 80 out of 939 papers were included in the final review. Ten examined conventional MRI (30% positive finding), 24 examined diffusion weighted imaging (54.17% positive finding), 23 examined functional MRI (82.61% positive finding), nine examined electro(magneto)encephalography (77.78% positive finding), and 14 examined other techniques (71% positive finding).
Conclusion: MRI was the most widely used technique, while functional techniques seem to be the most sensitive tools to evaluate PCS. The common functional patterns associated with symptoms of PCS were a decreased anti-correlation between the default mode network and the task positive network and reduced brain activity in specific areas (most often in the prefrontal cortex).
Significance: Our findings highlight the importance to use functional approaches which demonstrated a functional alteration in brain connectivity and activity in most studies assessing PCS.
Accessibility: Document exists in file
Language:
eng
Author:
Mortaheb, S.
Secondary author(s):
Filippini, M. M., Kaux, J.-F., Annen, J., Lejeune, N., Martens, G., Calderón, M. A. F., Laureys, S., Thibaut, A.
Document type:
Article
Number of reproductions:
3
Reference:
Mortaheb, S., Filippini, M. M., Kaux, J.-F., Annen, J., Lejeune, N., Martens, G., Calderón, M. A. F., Laureys, S., & Thibaut, A. (2021) Neurophysiological biomarkers of persistent post-concussive symptoms: A scoping review. Frontiers in Neurology, 12: 687197. https://doi.org/10.3389/fneur.2021.687197
2-year Impact Factor: 4.003|2020
Impact factor notes: Impact factor not available yet for 2021
Times cited: 10|2025-09-20
Indexed document: Yes
Quartile: Q2
Keywords: Neuroimaging / Persistent post-concussive symptoms / Diffusion weighted imaging / functional MRI / Electroencephalography / mTBI

Neurophysiological biomarkers of persistent post-concussive symptoms: A scoping review

Neurophysiological biomarkers of persistent post-concussive symptoms: A scoping review