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DocumentFinal report - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.01
Location: Arquivo PCA - Pasta 3/2000
Title:
Final report - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2002
URL:
http://www.bial.com/imagem/Bolsa5400_19022014.pdf
Abstract/Results: RESULTS:
Behavioural interventions including biofeedback represent an alternative or adjunctive therapeutic axis in the management of drug refractory epilepsy. Our previous study suggested that the modulation of the peripheral state of arousal as indexed by the Galvanic Skin Response (GSR) had considerable influence on cortical excitability, indicating the possible use of biofeedback in controlling seizure activity. In the present study we investigated the effect of the GSR biofeedback training on seizure frequency in patients with treatment resistant epilepsy. Eighteen patients with drug refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n = 10) or to a sham control biofeedback group (n = 8). Patients received a total of 12 sessions over four weeks, representing either real GSR biofeedback training, where subjects were trained to control their GSR by receiving feedback of their own GSR change on the computer screen, or sham training, where the feedback was unrelated to the subjects’ GSR.
Biofeedback training significantly reduced patients’ seizure frequency in the active biofeedback group (p = 0.005), but not the control group (p>0.10). This was manifest as a significant between group differences in seizure reduction (p = 0.016). Furthermore there was a correlation between degree of patients’ improvement in biofeedback performance and reduction of seizure frequency (rho = 0.736, p = 0.001), confirming that the effect of biofeedback treatment was related to physiological change. Our findings demonstrate that a behavioural intervention, GSR biofeedback training, may be associated with a significant reduction in seizure frequency in drug refractory epilepsy, highlighting the potential therapeutic value of this method.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Fenwick, P., Trimble, M. R.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR) / Intervention

Relatório final - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Relatório final - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

DocumentClinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.02
Location: Arquivo PCA - Pasta 3/2000
Title:
Clinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study
Publication year: 2004
URL:
http://www.sciencedirect.com/science/article/pii/S1525505003003950
Contents: http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=160&SID=V1leIhH4ysTdNpr3OrX&page=1&doc=1
Abstract/Results: ABSTRACT:
We investigated the effect of galvanic skin response (GSR) biofeedback training on seizure frequency in patients with treatment-resistant epilepsy. Eighteen patients with drug-refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n=10) or to a sham control biofeedback group (n=8). Biofeedback training significantly reduced seizure frequency in the active biofeedback group (P=0.017), but not the control group (P>0.10). This was manifest as a significant between-group difference in seizure reduction (P=0.01). Furthermore, there was a correlation between degree of improvement in biofeedback performance and reduction of seizure frequency (?=0.736, P=0.001), confirming that the effect of biofeedback treatment was related to physiological change. Our findings highlight the potential therapeutic value of GSR biofeedback in reducing seizure frequency in patients with drug-resistant epilepsy.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Fenwick, P., Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Goldstein, L., Fenwick, P., & Trimble, M. R. (2004). Clinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study. Epilepsy & Behaviour, 5(2), 216-223. https://doi.org/10.1016/j.yebeh.2003.12.003
2-year Impact Factor: 1.630|2004
Times cited: 79|2025-02-04
Indexed document: Yes
Quartile: Q2
Keywords: Galvanic skin response (GSR) / Biofeedback / Randomized controlled study / Drug refractory epilepsy / Seizure reduction

Clinical efficacy of biofeedback treatment on reducing seizures in adult epilepsy: a preliminary randomized controlled study

Clinical efficacy of biofeedback treatment on reducing seizures in adult epilepsy: a preliminary randomized controlled study
DocumentInfluence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.05
Location: Arquivo PCA - Pasta 3/2000
Title:
Influence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy
Publication year: 2004
URL:
http://www.google.pt/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&cad=rja&ved=0CDAQFjAA&url=http%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fdownload%3Fdoi%3D10.1.1.124.795%26rep%3Drep1%26type%3Dpdf&ei=tEjNUcjKIfSR7Aab1oBg&usg=AFQjCNHjj37kSx3p2CPlzuuH7h6K96Xs-w&sig2=PbDr5s-sOh4IwUUKET5uUw&bvm=bv.48572450,d.ZWU
Abstract/Results: ABSTRACT:
Negative amplitude shifts of cortical potential are related to seizure activity in epilepsy. Regulation of the cortical potential with biofeedback has been successfully used to reduce the frequency of some patients’ seizures. Although such behavioural treatments are increasingly popular as an alternative to pharmacotherapy, there has been no investigation of the mechanisms that might bridge the behavioural index of peripheral autonomic activity and the central regulation of arousal. Galvanic Skin Response (GSR) is a sensitive measurement of autonomic arousal and physiological state which reflects one’s behaviour. Thus we investigated the effect of peripheral autonomic modulation on cortical arousal with the future intention of using GSR biofeedback as a therapeutic treatment for epilepsy. The cortical negative potential was induced using the paradigm called Contingent Negative Variation (CNV) and measured in different physiological states. A high skin resistance state (reflecting a state of relaxation) and a low skin resistance state (reflecting a state of arousal), were engendered by two opposing procedures of GSR biofeedback. The CNV negative potential, acting as an index of cortical excitation, was significantly greater in amplitude at high levels of skin resistance (relaxed state) than at low levels of skin resistance (aroused state). Our results suggest an inverse relationship between a peripheral measure of autonomic arousal and an index of cortical arousal, the CNV. Moreover, we demonstrate modulation of this arousal-related potential by a behavioural intervention, indicating a potential therapeutic use of arousal biofeedback using GSR in the management of treatment-resistant epilepsy.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Critchley, H. D., Fenwick, P.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Goldstein, L., Critchley, H. D., & Fenwick, P. (2004). Influence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy. Epilepsy Research, 58(2-3), 185-193. https://doi.org/10.1016/j.eplepsyres.2004.02.004
2-year Impact Factor: 2.897|2004
Times cited: 41|2025-02-04
Indexed document: Yes
Quartile: Q1
Keywords: Contingent negative variation (CNV) / Galvanic Skin Response (GSR) / Biofeedback

Influence of sympathetic autonomic arousal on contingent negative variation: implications for a therapeutic behavioural intervention in epilepsy

Influence of sympathetic autonomic arousal on contingent negative variation: implications for a therapeutic behavioural intervention in epilepsy
DocumentChanges in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.06
Location: Arquivo PCA - Pasta 3/2000
Title:
Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy
Publication year: 2009
URL:
http://www.psychosomaticmedicine.org/content/71/1/84.full.pdf
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=19&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
OBJECTIVES:
To examine the immediate and sustained effects of volitional sympathetic modulation, using galvanic skin response (GSR) biofeedback training on cortical excitability in patients with drug-resistant epilepsy.
METHODS:
Ten patients undertook 12 sessions of GSR biofeedback training over 1 month, during which they were trained to increase sympathetic arousal, using GSR biofeedback. Contingent negative variation (CNV) (a slow cortical potential reflecting cortical arousal and excitability) and the related post imperative negative variation (PINV) were quantified before and after biofeedback treatment.
RESULTS:
A significant reduction in CNV amplitude was observed in both the short-term (within the first session, after 10 minutes of GSR biofeedback) and long-term (sustained after 12 training sessions). Specifically, the change in baseline CNV amplitude after the 12 training sessions correlated with a percentage reduction in seizure frequency. Furthermore, changes in baseline amplitude of the PINV also correlated with seizure reduction.
CONCLUSIONS:
Our findings demonstrate that behavioral enhancement of peripheral sympathetic tone (GSR) is associated with modulation of indices of cortical excitability. Moreover, GSR biofeedback training over repeated sessions was associated with a chronic baseline reduction in slow cortical potentials and concurrent therapeutic improvement.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D., Rothwell, J. C., Duncan, J. S., Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Critchley, H. D., Rothwell, J. C., Duncan, J. S., & Trimble, M. R. (2009). Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy. Psychosomatic Medicine, 71(1), 84-92. https://doi.org/10.1097/PSY.0b013e31818f667c
2-year Impact Factor: 4.236|2009
Times cited: 26|2025-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Biofeedback / Galvanic skin response (GSR) / Contingent negative variation (CNV) / Slow cortical potentials / Post imperative negative / Epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy
DocumentAn investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-088
Location: Arquivo PCA - Pasta 6/2002
Title:
088 - A neuropsychological examination of orbitofrontal cortex function in eating disorders
Duration: 2003-03 - 2004-09
Researcher(s):
Janet Treasure, Kate Tchanturia
Institution(s): Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Articles
Brochures (newsletters)
Language: eng
Related objects:
PT/FB/BL-2004-61
Author: Treasure, J.
Secondary author(s):
Tchanturia, K.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Mental health / Eating disorders / Cognitive processes / Decision-making

Reference code: PT/FB/BL-2002-088.06
Location: Arquivo PCA - Pasta 6/2002
Title:
An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements
Publication year: 2007
URL:
http://www.ncbi.nlm.nih.gov/pubmed/17521482
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=303&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
The objective of this study is to determine (a) if decision making ability is impaired in patients with anorexia nervosa (AN) and in people with good recovery from AN and (b) whether any impairment in decision making is associated with alterations in skin conductance responses (SCR). Patients with AN (n = 29), healthy controls comparable in age and IQ (HC, n = 29), and women long term recovered from AN (n = 14), completed the Iowa Gambling Task (IGT) while their SCR were measured. AN patients performed poorly in the IGT compared to the HC and to the recovered AN participants. AN patients had decreased anticipatory SCR prior to choosing cards and reduced SCR after losses compared to HC. IGT performance and the SCR of recovered AN participants did not differ from the HC. Decision making ability is impaired in AN. It is associated with a significantly attenuated SCR. Neither of these features are found in recovered AN. The association between impaired decision making ability and a decreased autonomic response is consistent with the predictions of the Somatic Marker Hypothesis.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
PT/FB/BL-2004-61.06
Author: Tchanturia, K.
Secondary author(s):
Liao, P.-C., Uher, R., Lawrence, N., Treasure, J., Campbell, I. C.
Document type:
Article
Number of reproductions:
1
Reference:
Tchanturia, K., Liao, P.-C., Uher, R., Lawrence, N., Treasure, J., Campbell, I. (2007). An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements. Journal of the International Neuropsychological Society, 13(4), 635-641. https://doi.org/10.1017/S1355617707070798
2-year Impact Factor: 2.402|2007
Times cited: 112|2025-02-04
Indexed document: Yes
Quartile: Q2
Keywords: Eating disorders / Recovery / Neuropsychology / Biological markers / Iowa gambling task (IGT) / Galvanic skin response (GSR)

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DocumentAn investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-061
Location: Arquivo PCA - Pasta 4/2004
Title:
061 - A neuropsychological examination of specific and global frontal lobe functions in siblings with and without eating disorders
Duration: 2005-08 - 2006-11
Researcher(s):
Ulrike Schmidt, Kate Tchanturia, Pei-Chi (Thomas) Liao
Institution(s): Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
1 Chapter book
Magazine of Eating Disorders Research Unit (2 copies)
Language: eng
Related objects:
PT/FB/BL-2002-88
Author: Schmidt, U.
Secondary author(s):
Tchanturia, K., Liao, P.-C.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Mental health / Eating disorders / Cognitive processes / Decision-making

Reference code: PT/FB/BL-2004-061.05
Location: Arquivo PCA - Pasta 4/2004
Title:
An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements
Publication year: 2007
URL:
http://www.ncbi.nlm.nih.gov/pubmed/17521482
Abstract/Results: ABSTRACT:
The objective of this study is to determine (a) if decision making ability is impaired in patients with anorexia nervosa (AN) and in people with good recovery from AN and (b) whether any impairment in decision making is associated with alterations in skin conductance responses (SCR). Patients with AN (n = 29), healthy controls comparable in age and IQ (HC, n = 29), and women long term recovered from AN (n = 14), completed the Iowa Gambling Task (IGT) while their SCR were measured. AN patients performed poorly in the IGT compared to the HC and to the recovered AN participants. AN patients had decreased anticipatory SCR prior to choosing cards and reduced SCR after losses compared to HC. IGT performance and the SCR of recovered AN participants did not differ from the HC. Decision making ability is impaired in AN. It is associated with a significantly attenuated SCR. Neither of these features are found in recovered AN. The association between impaired decision making ability and a decreased autonomic response is consistent with the predictions of the Somatic Marker Hypothesis.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
PT/FB/BL-2002-88.06
Author: Tchanturia, K.
Secondary author(s):
Liao, P.-C., Uher, R., Lawrence, N., Treasure, J., Campbell, I. C.
Document type:
Article-d
Number of reproductions:
1
Reference:
Tchanturia, K., Liao, P.-C., Uher, R., Lawrence, N., Treasure, J., & Campbell, I. C. (2007). An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements. Journal of the International Neuropsychological Society, 13(4), 635-641. https://doi.org/10.1017/S1355617707070798
2-year Impact Factor: 2.402|2007
Times cited: 112|2025-02-04
Indexed document: Yes
Quartile: Q2
Keywords: Eating disorders / Recovery / Neuropsychology / Biological markers / Iowa gambling task (IGT) / Galvanic skin response (GSR)

An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements

An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements
DocumentEffect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.09
Location: Arquivo PCA - Pasta 3/2000
Title:
Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2002
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/4%C2%BA_simposio.a110.html
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Fenwick, P., Goldstein, L., Lumsden, J., Trimble, M. R.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Nagai, Y., Fenwick, P., Goldstein, L., Lumsden, J., & Trimble, M. R. (2002). Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 4th Symposium of Fundação Bial (p. 448). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR)

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
DocumentEffect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.10
Location: Arquivo PCA - Pasta 3/2000
Title:
Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2004
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/5%C2%BA_simposio.a111.html
Abstract/Results: ABSTRACT:
Behavioural interventions including biofeedback represent an alternative or adjunctive therapeutic axis in the management of drug refractory epilepsy. Our previous study suggested that the modulation of the peripheral state of arousal as indexed by the Galvanic Skin Response (GSR) had considerable influence on cortical excitability, indicating the possible use of biofeedback in controlling seizure activity.
We investigated the effect of the GSR biofeedback training on seizure frequency in patients with treatment resistant epilepsy. Eighteen patients with drug refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n = 10) or to a sham control biofeedback group (n = 8). Patients received a total of 12 sessions over four weeks, representing either real GSR biofeedback training, where subjects were trained to decrease skin resistance using biofeedback, or sham training, where the feedback was unrelated to the subjects’ GSR. Biofeedback training significantly reduced patients’ seizure frequency in the active biofeedback group (p = 0.017), but not the control group (p>0.10). This was manifest as a significant between group difference in seizure reduction (p = 0.01). Our findings demonstrate that a behavioural intervention, GSR biofeedback training, may substantially reduce seizure frequency in drug refractory epilepsy, highlighting the potential therapeutic value of this method.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Nagai, Y., Trimble, M. R., Fenwick, P., Goldstein, L., & Lumsden, J. (2004). Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 5th Symposium of Fundação Bial (pp. 306-307). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR)

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
DocumentDiscrete-Trial SCP and GSR training and the interrelationship between central and peripheral arousal2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-163
Location: Arquivo PCA - Pasta 7/2004
Title:
163 - Effects of different biofeedback training procedures on quantitative electroencephalographic parameters of healthy subjects
Duration: 2005-01 - 2006-04
Researcher(s):
Martijn Arns, Wytze van der Zwaag, Erica Heesen, Rien Breteler
Institution(s): Brain Resource Company B.V., Nijmegen (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report (2 copies)
Article
Master's thesis
Language: eng
Author:
Arns, M.
Secondary author(s):
Van der Zwaag, W., Heesen, E., Breteler, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning

Reference code: PT/FB/BL-2004-163.02
Location: Arquivo PCA - Pasta 7/2004
Title:
Discrete-Trial SCP and GSR training and the interrelationship between central and peripheral arousal
Publication year: 2010
URL:
http://www.tandfonline.com/doi/abs/10.1080/10874208.2010.501501#.UelismxdYq4
Abstract/Results: ABSTRACT:
INTRODUCTION:
Slow Cortical Potential (SCP) neurofeedback and Galvanic Skin Response (GSR) biofeedback training were used to investigate self-regulatory control over central and peripheral arousal processes in two groups of healthy participants.
METHOD:
One group completed the SCP neurofeedback training procedure; the other group performed the GSR biofeedback procedure. Both groups underwent treatment while the other variable was passively recorded. The participants were instructed to either increase (Up trials) or decrease (Down trials) arousal. Twenty sessions were completed by each of the 18 participants over an 8-week period.
RESULTS:
Participants in each group performed better on the variable they were trained on. In the GSR group, a significant increase in performance over blocks was obtained for both trial types (Up and Down). In the SCP group a better performance on the Down trials was obtained. When comparing performance of both trial types, the SCP-trained participants showed a marginal increase and the GSR-trained participants a significant increase over time preliminary-training.
CONCLUSION:
Overall, the results showed that GSR regulation is easier to learn than SCP training with neurofeedback, that both variables can be trained in a bidirectional design, and that the SCP training subjects were predominantly able to learn performance at the Down trials. Preliminary results from the cross-correlations are inconsistent over trial types, trained parameters, and participants. However, the general trend shows a more positive correlation at the end of training compared to the start of training. Cross-correlation analysis suggests that this training encourages positive correlation between the SCP and GSR. Future research directions should be aimed at improving motivational conditions, implementing contingent reward principles, and controlling confounding variables.
Accessibility: Document does not exist in file
Language:
eng
Author:
Spronk, D.
Secondary author(s):
Kleinnijenhuis, M., Luijtelaar, G., Arns, M.
Document type:
Article
Number of reproductions:
1
Reference:
Spronk, D., Kleinnijenhuis, M., Luijtelaar, G., & Arns, M. (2010). Discrete-Trial SCP and GSR training and the interrelationship between central and peripheral arousal. Journal of Neurotherapy, 14(3), 217-228. https://doi.org/10.1080/10874208.2010.501501
2-year Impact Factor: N/A
Times cited: N/A
Indexed document: Yes
Quartile: N/A
Keywords: Electroencephalogram (EEG) biofeedback / Galvanic skin response (GSR) / Galvanic skin response biofeedback / Neurofeedback / Operant conditioning / Slow cortical potentials
DocumentBiofeedback and epilepsy2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.12
Location: Arquivo PCA - Pasta 3/2000
Title:
Biofeedback and epilepsy
Publication year: 2011
URL:
http://link.springer.com/article/10.1007%2Fs11910-011-0201-3
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=27&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
Biofeedback is a noninvasive behavioral treatment that enables a patient to gain volitional control over a physiological process. As a treatment for epilepsy, biofeedback interventions were explored from as early as the 1970s, concentrating on sensory motor rhythm (SMR) as a neurophysiologic parameter. Whereas SMR biofeedback aims to modulate frequency components of the electroencephalography (EEG), slow cortical potential (SCP) biofeedback (which was introduced in the 1990s) focuses on the regulation of the amplitude of cortical potential changes (DC shift). In its application to epilepsy, biofeedback using galvanic skin response (GSR), an electrodermal measure of sympathetic activity, is a relatively new cost-effective methodology. The present article first reviews biofeedback using SMR and SCP, for which efficacy and neural mechanisms are relatively well characterized. Then recent data regarding promising applications of GSR biofeedback will be introduced and discussed in detail.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y. (2011). Biofeedback and epilepsy. Current Neurology and Neuroscience Reports, 11(4), 443-450. https://doi.org/10.1007/s11910-011-0201-3
2-year Impact Factor: 3.455|2011
Times cited: 21|2025-02-10
Indexed document: Yes
Quartile: Q1
Keywords: Biofeedback / Volitional control / Sensory motor rhythm (SMR) / Slow cortical potentials (SCPs) / Galvanic skin response (GSR)