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BIAL Foundation
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DE:"Glucocorticoids"
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DocumentHigher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-036
Location: Arquivo PCA - Pasta 18/2006
Title:
036 - The psychophysiology of neurological abnormalities in first episode psychosis and in healthy individuals - A study using multimodal brain imaging
Duration: 2007-03 - 2010-09
Researcher(s):
Paola Dazzan, Philip McGuire, Carmine Pariante, Marta Di Forti, Julia Lappin, Valeria Mondelli
Institution(s): Division of Psychological Medicine, Institute of Psychiatry, London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
1 Article
Language: eng
Author:
Dazzan, P.
Secondary author(s):
McGuire, P., Pariante, C., Di Forti, M., Lappin, J., Mondelli, V.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders / Body structure and function / Audition / Movement / Vision

Reference code: PT/FB/BL-2006-036.02
Location: Arquivo PCA - Pasta 18/2006
Title:
Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis
Publication year: 2010
URL:
http://www.ncbi.nlm.nih.gov/pubmed/20071148
Abstract/Results: ABSTRACT:
This study investigated the relationship between cortisol secretion and hippocampal volume in first-episode psychosis and healthy controls. Hippocampal volume was measured by magnetic resonance imaging (MRI) in 24 first-episode psychosis patients and in 18 healthy controls, together with diurnal cortisol levels. Twelve patients received a second MRI scan at 3-month follow-up. Diurnal cortisol levels were inversely correlated with left hippocampal volume in patients, both at baseline and at follow-up, while no correlation was found in controls. Our findings suggest that smaller hippocampal volume in first-episode psychosis can partly be explained by stress-related processes in the brain, as measured by cortisol hyper-secretion.
Accessibility: Document does not exist in file
Language:
eng
Author:
Mondelli, V.
Secondary author(s):
Pariante, C., Navari, S., Aas, M., D'Albenzio, A., Di Forti, M., Handley, R., Hepgul, N., Marques, T. R., Taylor, H., Papadopoulos, A., Aitchison, K. J., Murray, R., Dazzan, P.
Document type:
Article
Number of reproductions:
1
Percentiles:
91.77|2.60
Reference:
Mondelli, V., Pariante, C., Navari, S., Aas, M., D'Albenzio, A., ... Dazzan, P. (2010). Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis. Schizophrenia Research, 119(1-3), 75-8. https://doi.org/10.1016/j.schres.2009.12.021
2-year Impact Factor: 4.374|2010
Times cited: 113|2026-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Cortisol / Hippocampus / Psychosis / Hypothalamic-pituitary-adrenal axis / Schizophrenia / Glucocorticoids

Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis

Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis

DocumentRelationship between obsessive compulsive disorder and cortisol: Systematic review and meta-analysis2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-206
Location: BF-GMS
Title:
206 - Developing a neurofunctional intervention for emotion regulation under stress
Duration: 2017-01 - 2023-01
Researcher(s):
Pedro Morgado, Carles Soriano Mas, Paulo Marques, Pedro Moreira, Ricardo Magalhães
Institution(s): Life and Health Sciences Research Institute - ICVS, School of Health Sciences, University of Minho, Braga (Portugal); Department of Psychiatry, Bellvitge Biomedical Research Institute - IDIBELL, Barcelona (Spain)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Morgado, P.
Secondary author(s):
Soriano-Mas, C., Marques, P., Moreira, P., Magalhães, R.
Number of reproductions:
1
Keywords:
Cognitive reappraisal / Stress / Neurofeedback / Electroencephalogram (EEG) / Psychophysiology

Reference code: PT/FB/BL-2016-206.04
Location: BF-GMS
Title:
Relationship between obsessive compulsive disorder and cortisol: Systematic review and meta-analysis
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0924977X19308752?via%3Dihub
Abstract/Results: ABSTRACT:
Altered stress response and consequent elevated levels of circulating glucocorticoids have been found in neuropsychiatric disorders such as depression or anxiety disorders and proposed to also play a role in the pathophysiology of obsessive-compulsive disorder (OCD). Despite the observation that stressful events may precede the disease onset or even exacerbate its symptoms, studies in this field do not always report consistent results regarding the cortisol profile of OCD patients. As such, a systematic review and meta-analysis was developed to clarify this issue. This systematic review and meta-analysis was elaborated according to the PRISMA method. The analytical procedures were implemented using Metafor package in R software. Nineteen studies were included in the systematic review and 18 were included in the meta-analysis. The meta-analytic results demonstrated that OCD patients had significantly higher cortisol levels compared to controls (d?=?0.76, SE = 0.146, p < 0.001). For studies using the average of multiple assessments, the standardized coefficient was significantly higher when compared to studies focusing on single measurements. Both the systematic review and meta-analysis suggest that cortisol levels are significantly higher in OCD patients than healthy individuals.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Sousa-Lima, J.
Secondary author(s):
Moreira, P. S., Raposo-Lima, C., Sousa, N., Morgado, P.
Document type:
Article
Number of reproductions:
1
Percentiles:
63.88|0.63
Reference:
Sousa-Lima, J., Moreira, P. S., Raposo-Lima, C., Sousa, N., & Morgado, P. (2019). Relationship between obsessive compulsive disorder and cortisol: Systematic review and meta-analysis. European Neuropsychopharmacology. https://doi.org/10.1016/j.euroneuro.2019.09.001
2-year Impact Factor: 3.853|2019
Times cited: 33|2026-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Cortisol / Glucocorticoids / Hypothalamic-pituitary-adrenal axis / OCD / Stress