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DocumentThe effect of experimenter gender on autonomic and subjective responses to pain stimuli2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-028
Location: Arquivo PCA - Pasta 10/2002
Title:
028 - Emotional factors in placebo analgesia: Psychophysiological Experiments
Duration: 2003-03 - 2006-10
Researcher(s):
Magne Arve Flaten, Oddmund Johansen, Terje Simonsen, Jan Brox, Arnstein Finset
Institution(s): Department of Clinical Research, University Hospital of North Norway (Norway)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Articles
Language: eng
Author:
Flaten, M.
Secondary author(s):
Johansen, O., Simonsen, T., Brox, J., Finset, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Cognitive processes / Emotion

Reference code: PT/FB/BL-2002-028.04
Location: Arquivo PCA - Pasta 10/2002
Title:
The effect of experimenter gender on autonomic and subjective responses to pain stimuli
Publication year: 2007
URL:
http://www.ncbi.nlm.nih.gov/pubmed/17134832
Abstract/Results: ABSTRACT:
Several studies have shown that male subjects report lower pain intensity to female compared to male experimenters. The present experiment examined whether experimenter gender also modulated autonomic pain responses. Sixty-four students (32 females) participated in a 2 Subject gender x 2 Experimenter gender x 15 Pain Tests mixed design. Six experimenters, three females and three males collected data. Heat pain was +48 degrees C induced to the right volar forearm. Subjective measurements consisted of pain intensity, pain unpleasantness, stress, arousal and mood. Autonomic responses were heart rate variability and skin conductance levels. The results revealed significant interactions between experimenter gender and subject gender on pain intensity and arousal, but there were no interactions in the physiological data. In conclusion, the lower pain report in male subjects to female experimenters is not mediated by changes in autonomic parameters, and the effect of experimenter gender is probably due to psychosocial factors.
Accessibility: Document does not exist in file
Language:
eng
Related objects:
PT/FB/BL-2006-161.09
Author: Aslaksen, P.
Secondary author(s):
Myrbakk, I., Høifødt, R., Flaten, M.
Document type:
Article
Number of reproductions:
1
Reference:
Aslaksen, P., Myrbakk, I., Høifødt, R., & Flaten, M. (2007). The effect of experimenter gender on autonomic and subjective responses to pain stimuli. Pain, 129(3), 260-268. https://doi.org/10.1016/j.pain.2006.10.011
2-year Impact Factor: 5.249|2007
Times cited: 148|2025-09-09
Indexed document: Yes
Quartile: Q1
Keywords: Experimenter gender / Pain report / Autonomic pain responses / Heart rate variability (HRV) / Gender roles / Heat pain / Subjective emotions / Stepwise regression
DocumentThe effect of experimenter gender on autonomic and subjective responses to pain stimuli2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-161
Location: Arquivo PCA - Pasta 12/2006
Title:
161 - The relation of mind to body. Psychophysiological studies of the placebo effect
Duration: 2007-01 - 2010-05
Researcher(s):
Magne Arve Flaten, Oddmund Johansen, Terje Simonsen, Per M. Aslaksen, Peter Lyby, Espen Bjorkedal
Institution(s): Department of Psychology, University of Tromso (Norway)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
2 Articles
Language: eng
Author:
Flaten, M.
Secondary author(s):
Johansen, O., Simonsen, T., Aslaksen, P., Lyby, P., Bjørkedal, E.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Emotion

Reference code: PT/FB/BL-2006-161.09
Location: Arquivo PCA - Pasta 12/2006
Title:
The effect of experimenter gender on autonomic and subjective responses to pain stimuli
Publication year: 2007
URL:
http://www.sciencedirect.com/science/article/pii/S0304395906005562
Abstract/Results: ABSTRACT:
Several studies have shown that male subjects report lower pain intensity to female compared to male experimenters. The present experiment examined whether experimenter gender also modulated autonomic pain responses. Sixty-four students (32 females) participated in a 2 Subject gender x 2 Experimenter gender x 15 Pain Tests mixed design. Six experimenters, three females and three males collected data. Heat pain was +48 degrees C induced to the right volar forearm. Subjective measurements consisted of pain intensity, pain unpleasantness, stress, arousal and mood. Autonomic responses were heart rate variability and skin conductance levels. The results revealed significant interactions between experimenter gender and subject gender on pain intensity and arousal, but there were no interactions in the physiological data. In conclusion, the lower pain report in male subjects to female experimenters is not mediated by changes in autonomic parameters, and the effect of experimenter gender is probably due to psychosocial factors.
Accessibility: Document does not exist in file
Language:
eng
Related objects:
PT/FB/BL-2002-28.04
Author: Aslaksen, P.
Secondary author(s):
Myrbakk, I., Høifødt, R., Flaten, M.
Document type:
Article-d
Number of reproductions:
1
Reference:
Aslaksen, P., Myrbakk, I., Høifødt, R., & Flaten, M. (2007). The effect of experimenter gender on autonomic and subjective responses to pain stimuli. Pain, 129(3), 260-268. https://doi.org/10.1016/j.pain.2006.10.011
2-year Impact Factor: 5.249|2007
Times cited: 148|2025-09-09
Indexed document: Yes
Quartile: Q1
Keywords: Experimenter gender / Pain report / Autonomic pain responses / Heart rate variability (HRV) / Gender roles / Heat pain / Subjective emotions / Stepwise regression
DocumentPlacebo analgesia and heart rate variability2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-161
Location: Arquivo PCA - Pasta 12/2006
Title:
161 - The relation of mind to body. Psychophysiological studies of the placebo effect
Duration: 2007-01 - 2010-05
Researcher(s):
Magne Arve Flaten, Oddmund Johansen, Terje Simonsen, Per M. Aslaksen, Peter Lyby, Espen Bjorkedal
Institution(s): Department of Psychology, University of Tromso (Norway)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
2 Articles
Language: eng
Author:
Flaten, M.
Secondary author(s):
Johansen, O., Simonsen, T., Aslaksen, P., Lyby, P., Bjørkedal, E.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Emotion

Reference code: PT/FB/BL-2006-161.11
Location: Arquivo PCA - Pasta 12/2006
Title:
Placebo analgesia and heart rate variability
Publication year: 2007
URL:
http://www.psychosomatic.org/AnMeeting/PastEvents/2007Abstracts.pdf
Abstract/Results: ABSTRACT:
The present experiment investigated whether administration of placebo affected heart rate variability during heat pain. It was hypothesized that the ratio of low frequent to high frequent (LF/HF) heart rate variability would decrease after administration of an inert substance together with information that it was a powerful painkiller. In a within subjects design, 20 participants (10 females) were tested on two separate days, one day for the placebo condition and one day for control. In the placebo condition, the participants received two capsules containing 75mg lactose each during the second of five pain tests, with information that the pills were a high dose of a standard overthe-counter analgesic with high pain analgesic effect on heat pain. In the
control condition, the same subjects underwent the same five pain tests, but without placebo administration. Pain tests consisted of heat pain (+46C, duration 240 seconds) to the forearm. ECG was recorded continuously for spectral analysis of heart rate variability. Subjective pain intensity, pain unpleasantness, stress and arousal were measured on VAS scales during each pain test. In addition, mood was measured by the SAM. Results revealed that the LF/HF ratio during painful stimulation decreased significantly in the
placebo condition compared to the control condition after placebo administration (F(1,19)=8.76, p<.01), but this effect was only significant for the first two pain tests after placebo administration. Moreover, a main effect of placebo on heart rate variability was found (F(1,19)=8.43, p<.01), with lower ratio of LF/HF in the placebo condition. There was lower pain intensity (F(1,19=14.99, p<.01) and pain unpleasantness (F(1,19)=4.74, p=.04) in the placebo condition compared to the control condition. Subjective stress during pain was decreased after placebo administration, and there was lower subjective stress in the placebo condition compared to the control condition (F(1,19)=13.06, p<.01). There were no significant effects on arousal or mood. The results from the present experiment suggest that placebo analgesia is accompanied by a reduction in cardiac autonomic activation and a reduction of subjective negative emotions.
Accessibility: Document does not exist in file
Language:
eng
Author:
Aslaksen, P.
Secondary author(s):
Flaten, M.
Document type:
Abstract
Number of reproductions:
1
Reference:
Aslaksen, P., & Flaten, M. (2007). Placebo analgesia and heart rate variability. Meeting abstracts. Psychosomatic Medicine, 69(1), A-32.
Indexed document: Yes
Keywords: Psychophysiology / Heat pain / Heart rate variability (HRV) / Placebo

Placebo analgesia and heart rate variability

Placebo analgesia and heart rate variability
Document(133) The relation of stress and heart rate variability to placebo analgesia2008

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-161
Location: Arquivo PCA - Pasta 12/2006
Title:
161 - The relation of mind to body. Psychophysiological studies of the placebo effect
Duration: 2007-01 - 2010-05
Researcher(s):
Magne Arve Flaten, Oddmund Johansen, Terje Simonsen, Per M. Aslaksen, Peter Lyby, Espen Bjorkedal
Institution(s): Department of Psychology, University of Tromso (Norway)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
2 Articles
Language: eng
Author:
Flaten, M.
Secondary author(s):
Johansen, O., Simonsen, T., Aslaksen, P., Lyby, P., Bjørkedal, E.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Emotion

Reference code: PT/FB/BL-2006-161.15
Location: Arquivo PCA - Pasta 12/2006
Title:
(133) The relation of stress and heart rate variability to placebo analgesia
Publication year: 2008
URL:
http://download.journals.elsevierhealth.com/pdfs/journals/1526-5900/PIIS1526590008000539.pdf
Abstract/Results: ABSTRACT:
The present experiment investigated whether administration of placebo affected heart rate variability during heat pain. It was hypothesized that the ratio of low frequent to high frequent (LF/HF) heart rate variability would decrease after administration of an inert substance together with information that it was a powerful painkiller. In a within subjects design, 63 participants (32 females) were tested on two separate days, one day for the placebo condition and one day for control. In the placebo condition, the participants received two capsules containing 75mg lactose each during the second of five pain tests, with information that the capsules were a high dose of a standard analgesic with high pain analgesic effect on heat pain. In the control condition, the same subjects underwent the same five pain tests, but without placebo administration. Pain tests consisted of heat pain (+46C, duration 240 seconds) to the forearm. ECG was recorded continuously. Subjective pain intensity, pain unpleasantness, stress and arousal were measured on VAS scales during each pain test. In addition, mood was measured by the SAM. Results revealed that the LF/HF ratio during painful stimulation decreased significantly in the placebo condition after placebo administration (F (1, 57) = 7.08, p = 0.01). There was lower pain intensity (F (1,62) = 20.53, p = 0.01) in the placebo condition compared to the control condition. Subjective stress during pain was decreased after placebo administration (F (1, 62) = 7.45, p = 0.01), and there was lower subjective stress in the placebo condition compared to the control condition (F (1, 62) = 5.39, p = 0.02). There were no significant effects on pain unpleasantness, arousal or mood. The results from the present experiment suggest that placebo analgesia is accompanied by a reduction in cardiac autonomic activation and a reduction of subjective stress.
Accessibility: Document does not exist in file
Language:
eng
Author:
Aslaksen, P.
Secondary author(s):
Flaten, M.
Document type:
Abstract
Number of reproductions:
1
Reference:
Aslaksen, P., & Flaten, M. (2008). (133) The relation of stress and heart rate variability to placebo analgesia. Journal of Pain, 9(4), Supplement 2, S9. https://doi.org/10.1016/j.jpain.2008.01.052
Indexed document: Yes
Keywords: Psychophysiology / Heat pain / Heart rate variability (HRV) / Placebo / Stress / Arousal / Mood

(133) The relation of stress and heart rate variability to placebo analgesia

(133) The relation of stress and heart rate variability to placebo analgesia
DocumentEvent-related potentials to painful stimuli are reduced during placebo analgesia2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-161
Location: Arquivo PCA - Pasta 12/2006
Title:
161 - The relation of mind to body. Psychophysiological studies of the placebo effect
Duration: 2007-01 - 2010-05
Researcher(s):
Magne Arve Flaten, Oddmund Johansen, Terje Simonsen, Per M. Aslaksen, Peter Lyby, Espen Bjorkedal
Institution(s): Department of Psychology, University of Tromso (Norway)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
2 Articles
Language: eng
Author:
Flaten, M.
Secondary author(s):
Johansen, O., Simonsen, T., Aslaksen, P., Lyby, P., Bjørkedal, E.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Emotion

Reference code: PT/FB/BL-2006-161.19
Location: Arquivo PCA - Pasta 12/2006
Title:
Event-related potentials to painful stimuli are reduced during placebo analgesia
Publication year: 2009
URL:
http://www.psychosomatic.org/AnMeeting/PastEvents/meeting2009/meetingAbstract2009.pdf
Abstract/Results: ABSTRACT:
PURPOSE:
Placebo analgesia refers to a reduction in recorded pain after administration of a capsule containing an inactive ingredient, with the information that it is a powerful painkiller. The present study investigated if placebo analgesia could be observed as reduced cortical response to heat stimuli. If placebo analgesia was associated with a reduced cortical response, this would indicate that the pain signal was reduced prior to cortical processing. A capsule containing an inactive ingredient was administrated with information that it was a powerful painkiller in the Placebo condition. Contact heat stimulation was administrated to the arm before and after the administration of the capsule. In the Natural History condition, heat stimuli were administrated without the capsule and the information.
SUBJECTS:
Forty (20 females) healthy volunteers aged 19 to 40 years.
METHODS:
Painful heat stimuli at 51 C with abrupt rise time and duration of less than 0.1sec were administrated by a thermode applied to the lower arm. Pain was recorded by a visual analogue scale, and by 32 channel electroencephalography. Event-related potentials (ERPs) to painful stimulation were computed by the Vision Analyzer software. A withinsubject design was used. All subjects were run in a Placebo condition where pain was applied before and after administration of a capsule with information that it was a painkiller, and a Natural History condition where pain was applied, but no capsule was administrated. The order of the conditions was counterbalanced.
RESULTS:
Pain unpleasantness was reduced in the Placebo condition compared to the Natural History condition (F = 7.95, p = .01). The P2 component in the ERP data was reduced in the Placebo condition compared to the Natural History condition (F = 3.39, p = .045).
CONCLUSIONS:
Placebo analgesic responding was observed as reduced pain report and as reduced cortical response to painful stimuli. This indicates that the pain signal to the brain is reduced by information that a powerful painkiller has been administrated, and that the placebo response is not due to response bias.
Accessibility: Document does not exist in file
Language:
eng
Author:
Aslaksen, P.
Secondary author(s):
Flaten, M.
Document type:
Abstract
Number of reproductions:
1
Reference:
Aslaksen, P., & Flaten, M. (2009). Event-related potentials to painful stimuli are reduced during placebo analgesia. Psychosomatic Medicine, 71(3), A - 103.
Indexed document: Yes
Keywords: Placebo analgesia / Heat pain / Cortical response / Event-related potential (ERP)

Event-related potentials to painful stimuli are reduced during placebo analgesia

Event-related potentials to painful stimuli are reduced during placebo analgesia
DocumentThe effect of singular nonverbal behaviours of experimenters on pain reports2024

Reference code: PT/FB/BL-2020-036.04
Location: BF-GMS
Title:
The effect of singular nonverbal behaviours of experimenters on pain reports
Publication year: 2024
URL:
https://doi.org/10.2147/jpr.s449150
Abstract/Results: ABSTRACT:
Introduction: Studies suggest facial expressions of caregivers may be important in placebo effects; however, this has not been
systematically tested. This experiment investigated the effects of caregivers’ singular positive nonverbal behaviours (NBs) on pain reports.
Methods: Fifty-one males and 53 females (total of 104) participants were randomized to four groups that were displayed positive
facial expressions, tone of voice, body movement, or neutral NBs of videotaped experimenters. Subjective reports of pain, stress,
arousal, and cardiac activity were obtained in a pre-test, a conditioning phase, and at a post-test. Four minutes of heat pain was induced in each test, and a placebo cream was administered before the conditioning and post-test in all groups.
Results: There were no differences between the NB groups in the reduced pain. Males had larger reduction in pain in the post-test,
and females had lower arousal than the opposite sex. During the conditioning, females had larger reduction in pain ie, unconditioned pain response (UPR). In females, the UPR predicted the reinforced expectation ie, increase in expectations from conditioning to posttest, and fear of minor pain negatively predicted both the UPR and reinforced expectation.
Discussion: Singular NBs of caregiver were weak to enhance placebo effects. Females had lower pain during conditioning, and the
UPR amplitude in females was associated with positive expectations. Moreover, for females, fear of minor pain weakened the UPR
and expectations of cream.
Conclusion: No NB of caregivers is more effective in reducing pain. Caregivers’ NBs are less effective when displayed individually.
Males and females may be different in underlying mechanisms of placebo effects.n
Number of reproductions: 1
2-year Impact Factor:
2.7|2022
Times cited: 0|2024-05-13
Indexed document: Yes

he effect of singular nonverbal behaviours of experimenters on pain reports

he effect of singular nonverbal behaviours of experimenters on pain reports
DocumentThe Effect of singular nonverbal behaviours of experimenters on pain reports2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology

Reference code: PT/FB/BL-2020-036.04
Location: BF-GMS
Title:
The Effect of singular nonverbal behaviours of experimenters on pain reports
Publication year: 2024
URL:
https://doi.org/10.2147/JPR.S449150
Abstract/Results: ABSTRACT:
Introduction: Studies suggest facial expressions of caregivers may be important in placebo effects; however, this has not been systematically tested. This experiment investigated the effects of caregivers' singular positive nonverbal behaviours (NBs) on pain reports.
Methods: Fifty-one males and 53 females (total of 104) participants were randomized to four groups that were displayed positive facial expressions, tone of voice, body movement, or neutral NBs of videotaped experimenters. Subjective reports of pain, stress, arousal, and cardiac activity were obtained in a pre-test, a conditioning phase, and at a post-test. Four minutes of heat pain was induced in each test, and a placebo cream was administered before the conditioning and post-test in all groups.
Results: There were no differences between the NB groups in the reduced pain. Males had larger reduction in pain in the post-test, and females had lower arousal than the opposite sex. During the conditioning, females had larger reduction in pain ie, unconditioned pain response (UPR). In females, the UPR predicted the reinforced expectation ie, increase in expectations from conditioning to post-test, and fear of minor pain negatively predicted both the UPR and reinforced expectation.
Discussion: Singular NBs of caregiver were weak to enhance placebo effects. Females had lower pain during conditioning, and the UPR amplitude in females was associated with positive expectations. Moreover, for females, fear of minor pain weakened the UPR and expectations of cream.
Conclusion: No NB of caregivers is more effective in reducing pain. Caregivers' NBs are less effective when displayed individually. Males and females may be different in underlying mechanisms of placebo effects.
Accessibility: Document exists in file
Language:
eng
Author:
Daniali, H.
Secondary author(s):
Ruben, M., Aslaksen, P. M., Fiskum, C., Kaptchuk, T., Flaten, M. A.
Document type:
Article
Number of reproductions:
1
Reference:
Daniali, H., Ruben, M. A., Aslaksen, P. M., Fiskum, C., Kaptchuk, T. J., & Flaten, M. A. (2024). The Effect of singular nonverbal behaviours of experimenters on pain reports. Journal of Pain Research, 17, 1345–1360. https://doi.org/10.2147/JPR.S449150
2-year Impact Factor: 2.5|2024
Times cited: 1|2025-09-27
Indexed document: Yes
Quartile: Q2
Keywords: Placebo effects / Subtle factors / Nonverbal behaviours / Heat pain / Experimenter effects / Pain report

The Effect of singular nonverbal behaviours of experimenters on pain reports

The Effect of singular nonverbal behaviours of experimenters on pain reports