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DocumentSeeing it coming: infants' brain responses to looming danger2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-002
Location: Arquivo PCA - Pasta 17/2004
Title:
002 - Event related brain dynamics: An independant component analysis of prospective control in adults and infants
Duration: 2005-02 - 2007-07
Researcher(s):
Ruud van der Weel, Audrey van der Meer, Ann-Mari Brubakk, Peter Svensson, Dawn Behne, David Lee, Marian Jongmans, Kerstin Rosander
Institution(s): Developmental Neuroscience Laboratory, Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Paper submitted for publication
(The project was not concluded and was closed in July 2007)
Language: eng
Author:
van der Weel, F. R.
Secondary author(s):
Brubakk, A.-M., Svensson, P., Behne, D., Lee, D., Jongmans, M., Rosander, K.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes / Perception / Developmental psychology

Reference code: PT/FB/BL-2004-002.01
Location: Arquivo PCA - Pasta 17/2004
Title:
Seeing it coming: infants' brain responses to looming danger
Publication year: 2009
URL:
http://www.ncbi.nlm.nih.gov/pubmed/19756463
Abstract/Results: ABSTRACT:
A fundamental property of most animals is the ability to see whether an object is approaching on a direct collision course and, if so, when it will collide. Using high-density electroencephalography in 5- to 11-month-old infants and a looming stimulus approaching under three different accelerations, we investigated how the young human nervous system extracts and processes information for impending collision. Here, we show that infants' looming related brain activity is characterised by theta oscillations. Source analyses reveal clear localised activity in the visual cortex. Analysing the temporal dynamics of the source waveform, we provide evidence that the temporal structure of different looming stimuli is sustained during processing in the more mature infant brain, providing infants with increasingly veridical time-to-collision information about looming danger as they grow older and become more mobile.
Accessibility: Document exists in file (previous version submitted for publication)
Copyright/Reproduction:
By permission
Language:
eng
Author:
Van der Weel, F. R.
Secondary author(s):
Van der Meer, A. L.
Document type:
Article
Number of reproductions:
1
Percentiles:
61.96|0.75
Reference:
van der Weel, F. R., & van der Meer, A. L. (2009). Seeing it coming: infants' brain responses to looming danger. Naturwissenschaften, 96(12), 1385-1391. https://doi.org/10.1007/s00114-009-0585-y
2-year Impact Factor: 2.316|2009
Times cited: 43|2026-02-04
Indexed document: Yes
Quartile: Q1
Keywords: Looming / Infant / High-density EEG / Theta oscillations / Source analysis / Tau-coupling analysis / Timing in the brain

Seeing it coming: infants' brain responses to looming danger

Seeing it coming: infants' brain responses to looming danger
DocumentI keep a close watch on this heart of mine: increased interoception in insomnia2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-252
Location: SEC PCA 252/12
Title:
252 - Sleep state misperception mispercieved
Duration: 2014-06 - 2017-01
Researcher(s):
Eus J. W. Van Someren, J. Ramautar
Institution(s): Netherlands Institute for Neuroscience, Dept. Sleep & Cognition, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress reports
Final reports
2 Articles
Language: eng
Author:
Van Someren, E.
Secondary author(s):
Ramautar, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Sleep and dreams / Biopsychological problems / Mental health / Sleep disorders / Brain structure and function / Cognitive processes / Memory / Consciousness

Reference code: PT/FB/BL-2012-252.03
Location: SEC PCA 252/12
Title:
I keep a close watch on this heart of mine: increased interoception in insomnia
Publication year: 2016
URL:
https://www.ncbi.nlm.nih.gov/pubmed/27634787
Abstract/Results: ABSTRACT:
STUDY OBJECTIVES:
Whereas both insomnia and altered interoception are core symptoms in affective disorders, their neural mechanisms remain insufficiently understood and have not previously been linked. Insomnia Disorder (ID) is characterized by sensory hypersensitivity during wakefulness and sleep. Previous studies on sensory processing in ID addressed external stimuli only, but not interoception. Interoceptive sensitivity can be studied quantitatively by measuring the cerebral cortical response to one's heartbeat (heartbeat-evoked potential, HEP). We here investigated whether insomnia is associated with increased interoceptive sensitivity as indexed by the HEP amplitude.
METHODS:
Sixty-four participants aged 21-70 years were recruited through www.sleepregistry.nl including 32 people suffering from ID and 32 age- and sex-matched controls without sleep complaints. HEPs were obtained from resting-state high-density electroencephalography (HD-EEG) recorded during evening wakeful rest in eyes-open (EO) and eyes-closed (EC) conditions of 5-minute duration each. Significance of group differences in HEP amplitude and their topographical distribution over the scalp were assessed by means of cluster-based permutation tests.
RESULTS:
In particular during EC, and to a lesser extent during EO, people with ID had a larger amplitude late HEP component than controls at frontal electrodes 376-500 ms after the R-wave peak. Source localization suggested increased neural activity time-locked to heartbeats in people with ID mainly in anterior cingulate/medial frontal cortices.
CONCLUSIONS:
People with insomnia show insufficient adaptation of their brain responses to the ever-present heartbeats. Abnormalities in the neural circuits involved in interoceptive awareness including the salience network may be of key importance to the pathophysiology of insomnia.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Ramautar, J., Colombo, M., Stoffers, D., Gomez-Herrero, G., van der Meijden, W. P., Te Lindert, B. H., van der Werf, Y., Van Someren, E.
Document type:
Article
Number of reproductions:
1
Percentiles:
91.42|2.16
Reference:
Wei, Y., Ramautar, J., Colombo, M., Stoffers, D., Gomez-Herrero, G., van der Meijden, W. P., Te Lindert, B. H., van der Werf, Y., & Van Someren, E. (2016). I keep a close watch on this heart of mine: increased interoception in insomnia. Sleep, 39(12), 2113-2124. https://doi.org/10.5665/sleep.6308
2-year Impact Factor: 4.923|2016
Times cited: 70|2026-02-06
Indexed document: Yes
Quartile: Q1
Keywords: Insomnia disorder / Interoception / Heartbeat-evoked potential / Event-related potential / High-density EEG / Hyperarousal / Resting state / Salience network
DocumentFinal report - Neural bases of time processing: combining neuroimaging techniques and clinical evidence2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-084
Location: Arquivo PCA - Pasta 13/2012
Title:
084 - Neural bases of time processing: combining neuroimaging techniques and clinical evidence
Duration: 2013-03 - 2016-04
Researcher(s):
Patrizia Bisiacchi, Gianna Maria Toffolo, Vincenza Tarantino, Elias Casula, Giovanni Mento, Demis Basso
Institution(s): Dipartimento di Psicologia Generale, Università di Padova (Italy)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Bisiacchi, P.
Secondary author(s):
Toffolo, G., Tarantino, V., Casula, E., Mento, G., Basso, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function / Biopsychological problems / Childhood and adolescent disorders / Autism spectrum disorder (ASD) / Neurodegenerative disorders / Parkinson's disease

Reference code: PT/FB/BL-2012-084.01
Location: Arquivo PCA - Pasta 13/2012
Title:
Final report - Neural bases of time processing: combining neuroimaging techniques and clinical evidence
Publication year: 2015
URL:
https://www.bial.com/imagem/Bolsa8412.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
There is growing interest in understanding cognitive mechanisms and neural bases of our sense of time. Despite the large amount of evidence, nevertheless, a number of open questions remains about the mechanisms by which our brain measures time.
AIM
The present project aimed at identifying whether there is a core mechanism for timing processes. Specifically, we investigated which brain areas subserve such mechanism, and their functional role.
METHODS
1. High-density EEG study
2. rTMS study
3. EEG-TMS study
4. Clinical studies
RESULTS
High-density EEG study - Brain source analysis of S1- and ISI-related ERP activity revealed activation of sensorial cortical areas and the supplementary motor area (SMA), respectively. We suggest that this area is the major cortical generator of the temporal CNV reflecting an automatic, action-independent mechanism underlying temporal expectancy.
rTMS study - The results showed that frontal TMS produced differential effects as a function of type of cuing. In symbolic cuing, TMS on either left or right frontal site (vs. sham) increased temporal orienting effects by reducing reaction times invalid trials. In rhythmic cuing, however, frontal TMS did not influence performance.
EEG-TMS study - Our results confirmed the reliability of the TMS-evoked N100 as a marker of cortical inhibition and provide insight into the neuromodulatory effects of 1-Hz rTMS.
Clinical studies - On-line comparison process between the two time intervals, re?ected by the P1-P2 and LPCt amplitude and morphology, was impaired in patients with Parkinson’s disease and support the presence of a de?cit of memory for time in such clinical population.
CONCLUSIONS
Specific ERP components were shown to index processing of short interval durations. Our findings support the involvement of contingent negative variation (CNV) observed in frontal regions in time processing. Remarkably, the neural generators of the temporal CNV
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Bisiacchi, P.
Secondary author(s):
Toffolo, G., Tarantino, V., Casula, E., Mento, G., Basso, D.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Time processing / High-density EEG / TMS / Parkinson Disease
DocumentFinal report - Sleep state misperception mispercieved2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-252
Location: SEC PCA 252/12
Title:
252 - Sleep state misperception mispercieved
Duration: 2014-06 - 2017-01
Researcher(s):
Eus J. W. Van Someren, J. Ramautar
Institution(s): Netherlands Institute for Neuroscience, Dept. Sleep & Cognition, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress reports
Final reports
2 Articles
Language: eng
Author:
Van Someren, E.
Secondary author(s):
Ramautar, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Sleep and dreams / Biopsychological problems / Mental health / Sleep disorders / Brain structure and function / Cognitive processes / Memory / Consciousness

Reference code: PT/FB/BL-2012-252.01
Location: SEC PCA 252/12
Title:
Final report - Sleep state misperception mispercieved
Publication year: 2016
URL:
https://www.bial.com/imagem/Bolsa%2025212.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
Whereas psychophysiological insomnia is the most common health complaint and has serious consequences, the neural correlates of altered perception and consciousness are insufficiently known.
AIM
We here aimed to evaluate electroencephalographic (EEG) markers of hyperarousal, cortical inhibition and attentional filtering during resting state.
METHOD
High-density EEG and electrocardiography (ECG) were recorded in up to 51 people complaining about insomnia and 43 matched controls. Analyses including source estimation quantified the spatiotemporal, spectral, and long-range temporal correlation (LRTC) properties of the EEG during resting state, including Heartbeat Evoked Potentials (HEP).
RESULTS
People that complain about insomnia showed less power in a narrow upper alpha band around 11.7 Hz over bilateral frontal and left temporal regions. They moreover showed more power in a broad beta frequency range (16.3-40 Hz) across the scalp. In addition, they showed a larger amplitude late HEP component than controls at frontal electrodes 376-500 ms after the R-wave peak in anterior cingulate/medial frontal cortices. Finally, individuals who experienced worse sleep quality had stronger LRTC.
CONCLUSIONS
The findings suggest hyperarousal, insufficient cerebral cortical inhibition and attentional filtering, and insufficient interoceptive adaptation of their brain responses to the ever-present heartbeats. The findings provide insight into the neural correlates of sleep complaints including enhanced awareness that could underlie sleep state misperception.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Van Someren, E.
Secondary author(s):
Ramautar, J.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiological insomnia / High-density EEG / Sleep misperception / Consciousness
DocumentEEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-190
Location: BF-GMS
Title:
190 - Sleeping body, sentient mind? Searching for the neural bases of conscious experiences during sleep
Duration: 2017-10 - 2019-06
Researcher(s):
Eus Van Someren, Yishul Wei
Institution(s): Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Author: Van Someren, E.
Secondary author(s):
Wei, Y.
Number of reproductions:
1
Keywords:
Interoception / Insomnia / Neural correlates of consciousness / Salience / Psychophysiology

Reference code: PT/FB/BL-2016-190.04
Location: BF-GMS
Title:
EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content
Publication year: 2018
URL:
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00395/full
Abstract/Results: ABSTRACT:
People with Insomnia Disorder (ID) not only experience abundant nocturnal mentation, but also report altered spontaneous mental content during daytime wakefulness, such as an increase in bodily experiences (heightened somatic awareness). Previous studies have shown that resting-state EEG can be temporally partitioned into quasi-stable microstates, and that these microstates form a small number of canonical classes that are consistent across people. Furthermore, the microstate classes have been associated with individual differences in resting mental content including somatic awareness. To address the hypothesis that altered resting mental content in ID would be reflected in an altered representation of the corresponding EEG microstates, we analyzed resting-state high-density EEG of 32 people with ID and 32 age- and sex-matched controls assessed during 5-min eyes-closed wakefulness. Using data-driven topographical k-means clustering, we found that 5 microstate classes optimally explained the EEG scalp voltage map sequences across participants. For each microstate class, 3 dynamic features were obtained: mean duration, frequency of occurrence, and proportional coverage time. People with ID had a shorter mean duration of class C microstates, and more frequent occurrence of class D microstates. The finding is consistent with previously established associations of these microstate properties with somatic awareness, and increased somatic awareness in ID. EEG microstate assessment could provide objective markers of subjective experience dimensions in studies on consciousness during the transition between wake and sleep, when self-report is not possible because it would interfere with the very process under study. Addressing somatic awareness may benefit psychotherapeutic treatment of insomnia.
Accessibility: Document exists in file
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Ramautar, J. R., Colombo, M. A., Te Lindert, B. H. W., Van Someren, E. J. W.
Document type:
Article
Number of reproductions:
1
Percentiles:
77.52|1.30
Reference:
Wei, Y., Ramautar, J. R., Colombo, M. A., Te Lindert, B. H. W., & Van Someren, E. J. W. (2018). EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content. Frontiers in Psychiatry, 9: 395. https://doi.org/10.3389/fpsyt.2018.00395
2-year Impact Factor: 3.161|2018
Times cited: 33|2026-02-11
Indexed document: Yes
Quartile: Q2
Keywords: Electrical neuroimaging / High-density EEG / Insomnia disorder / Mental content / Microstate / Resting state / Somatic awareness / Wakefulness

EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content

EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content