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DocumentFinal report - Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes2008

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-120
Location: Arquivo PCA - Pasta 8/2006
Title:
120 - Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes
Duration: 2007-02 - 2009-01
Researcher(s):
Isabel Maria Pereira Leal, Rui Filipe Nunes Pais de Oliveira, Luís Gonçalves Sobrinho, Rita Maria Morgado Gomez
Institution(s): Centro de Investigação e Intervenção, Instituto Superior de Psicologia Aplicada, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: por
Author:
Leal, I.
Secondary author(s):
Oliveira, R., Sobrinho, L. G., Gomez, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Psychoneuroimmunology / Endocrinology / Affective and social behavior / Parenthood

Reference code: PT/FB/BL-2006-120.01
Location: Arquivo PCA - Pasta 8/2006
Title:
Final report - Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes
Publication year: 2008
URL:
http://www.bial.com/imagem/Bolsa12006_16102013.pdf
Abstract/Results: RESULTS:
(Note: The current project produced a relatively large amount of data; the results reported next constitute the ones the investigators consider most relevant.)
Animal studies have been documenting the association between hormonal changes and the emergence of parental behavior in both males and females of a variety of species. Human data have been very scarce, but findings of three previous studies showed that hormone levels of human fathers can change during the reproductive period. The results of the current project constitute a step forward in the study of the psychoendocrinology of parental behavior, by indicating that hormone changes experienced by men during their partner’s pregnancy associate to the expression of paternal involvement after the birth. Thus, fathers who presented higher levels of paternal behavior after the birth (HIF, high-involvement fathers), but not less involved fathers (LIF), were found to have increased levels of Progesterone, Estradiol and Testosterone during pregnancy comparing to postpartum hormone levels and to hormone levels of controls; in addition, Prolactin levels were found to be increased from pregnancy to postpartum in HIF, but not in LIF, whereas Cortisol levels were found to be elevated after the birth in LIF only. These results are generally consistent with previous findings on the neuroendocrinology of paternal behavior in mammals, and add support to the hypothesis that in bi-parental mammals, including humans, the expression of paternal and maternal behavior involve homologous neuroendocrine mechanisms. These findings can contribute to ‘validate’ the experience of more parentally motivated men, as well as to inform about conditions in which pro-social behavior, including parental investment, is compromised.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
por
Author:
Leal, I.
Secondary author(s):
Oliveira, R., Gomez, R., Sobrinho, L. G.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Endocrinology / Hormones / Parental behavior / Paternal involvement / Pregnancy

Final report - Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes

Final report - Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes
DocumentPsicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes [Psicoendocrinology of the human parental behaviour: Hormonal changes, couvade syndrome and parent responsivity in expecting-parents]2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-120
Location: Arquivo PCA - Pasta 8/2006
Title:
120 - Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes
Duration: 2007-02 - 2009-01
Researcher(s):
Isabel Maria Pereira Leal, Rui Filipe Nunes Pais de Oliveira, Luís Gonçalves Sobrinho, Rita Maria Morgado Gomez
Institution(s): Centro de Investigação e Intervenção, Instituto Superior de Psicologia Aplicada, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: por
Author:
Leal, I.
Secondary author(s):
Oliveira, R., Sobrinho, L. G., Gomez, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Psychoneuroimmunology / Endocrinology / Affective and social behavior / Parenthood

Reference code: PT/FB/BL-2006-120.06
Location: Arquivo PCA - Pasta 8/2006
Title:
Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes [Psicoendocrinology of the human parental behaviour: Hormonal changes, couvade syndrome and parent responsivity in expecting-parents]
Publication year: 2010
URL:
http://www.bial.com/simposio/Livro_de_Actas_8_Simposio.pdf
Abstract/Results: ABSTRACT:
OBJECTIVES:
Animal studies have been documenting the association between hormonal changes and the emergence of parental behavior in both males and females of a variety of non-human species. Data on the psychoendocrinology of human parental behavior is very scarce, but preliminary findings by Storey et al. (2000), Berg and Wynne-Edwards (2001; 2002) and Fleming et al. (2002) showed that hormone levels of human fathers can change during the reproductive period. None of these pioneering studies, however, analyzed if hormone changes in expectant fathers associate with the expression of paternal behavior after birth.
METHOD:
In this study, serum levels of prolactin (PRL) and salivary levels of testosterone (T), progesterone (P), estradiol (E2) and cortisol (CORT) were measured five times throughout the reproductive period (three times during pregnancy and two times after the birth) in an initial sample of 32 expectant fathers (EF). Hormone levels of 15 control men (C) were also measured at same time intervals. In addition, paternal behavior after the birth was evaluated in EF with psychometric measures.
RESULTS:
Fathers who presented higher levels of paternal behavior after the birth (HIF, high-involvement fathers), but not less involved fathers (LIF), showed increased levels of P and E2 during pregnancy comparing to postpartum hormone levels and to hormone levels of controls. In addition, PRL levels increased from the pregnancy to the postpartum period in HIF, but not in LIF, whereas CORT levels were significantly increased following the birth in LIF only. Finally, though T levels were high during pregnancy and low after the birth for
all fathers, changes in T were more pronounced in HIF.
DISCUSSION:
Results are generally consistent with previous findings on the neuroendocrinology of paternal behavior in mammals, and add support to the hypothesis that in bi-parental mammals, including humans, the expression of paternal and maternal behavior involve homologous neuroendocrine mechanisms. Research in this area can contribute to ‘validate’ the experience of more involved fathers and to inform about conditions in which pro-social behavior, including parental investment, is compromised.
Accessibility: Document does not exist in file
Language:
eng
Author:
Leal, I.
Secondary author(s):
Oliveira, R., Sobrinho, L. G., Gomez, R.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Leal, I., Oliveira, R., Sobrinho, L. G., & Gomez, R. (2010). Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes [Psicoendocrinology of the human parental behaviour: Hormonal changes, couvade syndrome and parent responsivity in expecting-parents]. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 8th Symposium of Fundação Bial (pp. 228-229). Porto: Fundação Bial.
Indexed document: No
Keywords: Hormones / Parental behavior / Paternal involvement / Pregnancy

Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes [Psicoendocrinology of the human parental behaviour: Hormonal changes, couvade syndrome and parent responsivity in expecting-parents]

Psicoendocrinologia do comportamento parental humano: Alterações hormonais, síndrome de couvade e responsividade parental em pais-expectantes [Psicoendocrinology of the human parental behaviour: Hormonal changes, couvade syndrome and parent responsivity in expecting-parents]
DocumentNeural adaptation to changes in self-voice during puberty2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-102
Location: BF-GMS
Title:
102 - Identifying altered resting state connectivity dynamics as predictors of auditory verbal hallucinations (AVH)
Duration: 2023-09
Researcher(s):
Sonja Kotz, Hanna Honcamp, Michael Schwartze, David Linden, Federico de Martino, Ana Pinheiro
Institution(s): Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Articles
Language: eng
Notes:
Ongoing project
Author: Kotz, S. A.
Secondary author(s):
Honcamp, H., Schwartze, M., Linden, D. E., De Martino, F., Pinheiro, A. P.
Number of reproductions:
1
Keywords:
Auditory verbal hallucinations / Resting state / Brain dynamics / Hidden semi-markov modeling / Psychophysiology

Reference code: PT/FB/BL-2022-102.03
Location: BF-GMS
Title:
Neural adaptation to changes in self-voice during puberty
Publication year: 2024
URL:
https://doi.org/10.1016/j.tins.2024.08.001
Abstract/Results: ABSTRACT:
The human voice is a potent social signal and a distinctive marker of individual identity. As individuals go through puberty, their voices undergo acoustic changes, setting them apart from others. In this article, we propose that hormonal fluctuations in conjunction with morphological vocal tract changes during puberty establish a sensitive developmental phase that affects the monitoring of the adolescent voice and, specifically, self–other distinction. Furthermore, the protracted maturation of brain regions responsible for voice processing, coupled with the dynamically evolving social environment of adolescents, likely disrupts a clear differentiation of the self-voice from others’ voices. This socioneuroendocrine framework offers a holistic understanding of voice monitoring during adolescence.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2020-146.07
Author: Pinheiro, A. P.
Secondary author(s):
Aucouturier, J., Kotz, S. A.
Document type:
Article-d
Number of reproductions:
1
Reference:
Pinheiro, A. P., Aucouturier, J., & Kotz, S. A. (2024). Neural adaptation to changes in self-voice during puberty. Trends in Neurosciences, 47, 777-787. https://doi.org/10.1016/j.tins.2024.08.001
2-year Impact Factor: 14.6|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2025-02-19
Indexed document: Yes
Quartile: Q1
Keywords: Adolescence / Hormones / Brain maturation / Sensitive period / Sensory feedback / Hallucinations
DocumentNeural adaptation to changes in self-voice during puberty2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-146
Location: BF-GMS
Title:
146 - The me and the I: Dissociating ownership and agency in sensorimotor processing
Duration: 2021-09
Researcher(s):
Ana Pinheiro, Sonja Kotz, Michael Schwartze
Institution(s): Centro de Investigação em Ciência Psicológica - CICPSI, Faculdade de Psicologia da Universidade de Lisboa (Portugal); Faculty of Psychology and Neuroscience, University of Maastricht (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Article
Language: eng
Notes:
Ongoing project
Author: Pinheiro, A. P.
Secondary author(s):
Kotz, S., Schwartze, M.
Number of reproductions:
1
Keywords:
Self / Agency / Ownership / Electroencephalogram (EEG) / Psychophysiology

Reference code: PT/FB/BL-2020-146.07
Location: BF-GMS
Title:
Neural adaptation to changes in self-voice during puberty
Publication year: 2024
URL:
https://doi.org/10.1016/j.tins.2024.08.001
Abstract/Results: ABSTRACT:
The human voice is a potent social signal and a distinctive marker of individual identity. As individuals go through puberty, their voices undergo acoustic changes, setting them apart from others. In this article, we propose that hormonal fluctuations in conjunction with morphological vocal tract changes during puberty establish a sensitive developmental phase that affects the monitoring of the adolescent voice and, specifically, self–other distinction. Furthermore, the protracted maturation of brain regions responsible for voice processing, coupled with the dynamically evolving social environment of adolescents, likely disrupts a clear differentiation of the self-voice from others’ voices. This socioneuroendocrine framework offers a holistic understanding of voice monitoring during adolescence.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2022-102.03
Author: Pinheiro, A. P.
Secondary author(s):
Aucouturier, J., Kotz, S. A.
Document type:
Article
Number of reproductions:
1
Reference:
Pinheiro, A. P., Aucouturier, J., & Kotz, S. A. (2024). Neural adaptation to changes in self-voice during puberty. Trends in Neurosciences, 47, 777-787. https://doi.org/10.1016/j.tins.2024.08.001
2-year Impact Factor: 14.6|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2025-02-20
Indexed document: Yes
Quartile: Q1
Keywords: Adolescence / Hormones / Brain maturation / Sensitive period / Sensory feedback / Hallucinations