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BIAL Foundation
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Type Title Begin End
DocumentInformation and spirit2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-065
Location: Arquivo PCA - Pasta 8/2004
Title:
065 - An investigation into the possibility of a stimulus-response causal relationship in the electronic voice phenomenon
Duration: 2005-02 - 2007-03
Researcher(s):
Alexander MacRae, Charl Vorster
Institution(s): Skyelab, Portree, Scotland (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
MacRae, A.
Secondary author(s):
Vorster, C.
Number of reproductions:
2
Keywords:
Parapsychology / Survival after bodily death / Electronic voice phenomenon (EVP)

Reference code: PT/FB/BL-2004-065.04
Location: Arquivo PCA - Pasta 8/2004
Title:
Information and spirit
Publication year: 2011
URL:
http://www.benthamscience.com/open/toiscij/articles/V003/SI0001TOISCIJ/54TOISCIJ.pdf
Abstract/Results: ABSTRACT:
Definitions that relate to each other are derived for Information and spirit. An experiment that seeks to stimulate the phonological store is described and the responses obtained analyzed, using a unique monitoring method based on variations in electrical permittivity when neurons fire. The importance of the non-sensory inputs to the sub-vocal rehearsal system in the phonological lop is mentioned. An experiment is outlined wherein a mental stimulus is applied to the subject and the electrical response is monitored and converted to audible speech. This is thus non-vocal speech and its characteristics are examined in relation to the original stimuli. The results revealed openings for further research.
Accessibility: Document does not exist in file
Language:
eng
Author:
MacRae, A.
Document type:
Article
Number of reproductions:
2
Reference:
MacRae, A. (2011). Information and Spirit. The Open Information Science Journal, 3, 54-62. https://doi.org/10.2174/1874947X01103010054
Indexed document: No
Keywords: Information / Spirit / Question & answer / Phonological loop / Neurons / Electrical permittivity

Information and spirit

Information and spirit

DocumentPlacebo analgesia in the dental clinic: positive information about treatment reduces pain in dental patients2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-186
Location: Arquivo PCA - Pasta 12/2010
Title:
186 - Brain mechanisms of placebo analgesia
Duration: 2011-03 - 2014-01
Researcher(s):
Magne Arve Flaten, Per M. Aslaksen, Torgil R. Vangberg, Odd Petter Eldevik, Jan Bergdahl, Sara Vambheim, Just C. Thoner
Institution(s): University of Tromsø and University Hospital of North Norway, Tromso (Norway)
Contents: Contents:
Bursary agreement
Application form + 12 articles (previous project team publications)
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Flaten, M.
Secondary author(s):
Aslaksen, P., Vangberg, T., Eldevik, O., Bergdahl, J., Vambheim, S., Thoner, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Emotion / Brain structure and function

Reference code: PT/FB/BL-2010-186.15
Location: Arquivo PCA - Pasta 10/2010
Title:
Placebo analgesia in the dental clinic: positive information about treatment reduces pain in dental patients
Publication year: 2013
URL:
http://www.psychosomatic.org/AnMeeting/PDF/2013abstractBooklet.pdf
Abstract/Results: ABSTRACT:
BACKGROUND:
Information about the effectiveness of treatment has been found to reduce pain, termed placebo analgesia. It was investigated whether information that suggested that minimal pain would be experienced during filling therapy, could reduce the pain associated with that procedure. All patients received the same amount of
anaesthesia and similar procedures during filling therapy. It was predicted that extended information should reduce pain, and that the reduction in pain should be associated with a reduction in stress.
METHODS:
44 patients (24 females, 17-68 yrs) going through composite restoration therapy with anaesthesia in a molar or premolar, participated. The design was a 2 Information (Extended, Standard) by 4 Test mixed design. Patients were randomized to two groups: The Standard Info group (N=22) received information that was short but informative about the pain they might experience under and after treatment. Words like pain, sensitivity and unpleasant were used. The Extended Info group received information that and focused on the
positive effects. The Fear of Pain Questionnaire III was administrated. Subjective pain intensity and pain unpleasantness, and stress were recorded by numerical rating scales before, during, immediately after,
and 15 minutes after treatment. The patients were all given local anaesthesia in the form of xylocain dental adrenalin 2% + 12.5 microg/ml adrenalin.
RESULTS:
Pain was 2.6 points lower in the Extended Info group compared to the Standard Info group during treatment (p = .033). There were no differences in pain levels in the other Tests. Extended Info reduced stress slightly. Low tension before treatment correlated with lower pain during treatment (p = .004). High fear of pain correlated with high stress prior to treatment (p = .002).
CONCLUSIONS:
Providing positive information about the anaesthetic and the dental procedure reduced pain compared to standard information. Subjects high in fear of pain displayed the highest stress prior to the dental procedure, and high stress prior to the dental procedure correlated with high pain during the procedure. The information partly reduced pain by reducing stress prior to the dental procedure. The magnitude of the analgesic effect of the information was about 2.6 points on an 11-point numerical rating scale, clinically significant. Taken together the study shows that providing information that underscores the effectiveness of the painkiller, informs the patient that the damage is small, and that informs the patient that he/she has control of the situation, reduces pain induced by the dental procedure.
Accessibility: Document does not exist in file
Language:
eng
Author:
Hunsbeth, P.
Secondary author(s):
Flaten, M.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Hunsbeth, P., & Flaten, M. A. (2013). Placebo analgesia in the dental clinic: positive information about treatment reduces pain in dental patients. In Meeting Abstracts 71st American Psychosomatic Society Annual Scientific Meeting, Miami, FL (A-154).
Indexed document: No
Keywords: Pain / Placebo analgesia / Information

Placebo analgesia in the dental clinic: positive information about treatment reduces pain in dental patients

Placebo analgesia in the dental clinic: positive information about treatment reduces pain in dental patients

DocumentThe temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-161
Location: Arquivo PCA - Pastas 22/2010
Title:
161 - Investigating the function of synaptic competition in memory formation and mental retardation
Duration: 2011-09 - 2015-09
Researcher(s):
Inbal Israely, Anna Hobbiss, Ana Vaz
Institution(s): Champalimaud Foundation, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Israely, I.
Secondary author(s):
Hobbiss, A., Vaz, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes / Memory / Biopsychological problems / Childhood and adolescent disorders / Mental retardation

Reference code: PT/FB/BL-2010-161.06
Location: BF-GMS
Title:
The temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines
Publication year: 2023
Abstract/Results:
ABSTRACT:
Learning is thought to involve physiological and structural changes at individual synapses. Synaptic plasticity has predominantly been studied using regular stimulation patterns, but neuronal activity in the brain normally follows a Poisson distribution. We used two-photon imaging and glutamate uncaging to investigate the structural plasticity of single dendritic spines using naturalistic activation patterns sampled from a Poisson distribution. We showed that naturalistic activation patterns elicit structural plasticity that is both NMDAR and protein synthesis-dependent. Furthermore, we uncovered that the longevity of structural plasticity is dependent on the temporal structure of the naturalistic pattern. Finally, we found that during the delivery of the naturalistic activity, spines underwent rapid structural growth that predicted the longevity of plasticity. This was not observed with regularly spaced activity. These data reveal that different temporal organizations of the same number of synaptic stimulations can produce rather distinct short and long-lasting structural plasticity.
Accessibility: Document exists in file
Language:
eng
Author:
Argunsah, A. Ö.
Secondary author(s):
Israely, I.
Document type:
Article
Number of reproductions:
1
Percentiles:
5
Reference:
Argunsah, A. Ö., & Israely, I. (2023). The temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines. iScience, 26(6), 106835. https://doi.org/10.1016/j.isci.2023.106835
2-year Impact Factor: 4.6|2023
Times cited: 1|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Long-term potentiation / Protein-synthesis / Natural stimulation / LTP / Transmission / Induction / Mechanism / Synapses / Camkii / Information

The temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines

The temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines