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DocumentNeurocognitive performance in children aged 9 – 12 years who present putative antecedents of schizophrenia2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2006-035.04
Location: Arquivo PCA - Pasta 17/2006
Title:
Neurocognitive performance in children aged 9 – 12 years who present putative antecedents of schizophrenia
Publication year: 2010
URL:
http://www.sciencedirect.com/science/article/pii/S0920996410013551
Abstract/Results: ABSTRACT:
BACKGROUND:
We previously developed a novel method of identifying children aged 9-12 years who may be at elevated risk of developing schizophrenia and the spectrum disorders because they present a triad of putative antecedents of schizophrenia (ASz). The present study aimed to determine whether ASz children also present neurocognitive deficits that are commonly observed in patients with schizophrenia.
METHODS:
Twenty-eight ASz children and 28 typically-developing (TD) children without the antecedents of schizophrenia completed a battery of neurocognitive tests assessing seven domains of function: General intelligence, scholastic achievement, verbal memory, visual memory, working memory, executive function (EF)-verbal fluency, and EF-inhibition.
RESULTS:
Relative to TD children, the ASz group showed poorer performance on all neurocognitive tests (mean Cohen's d effect size=0.52). In linear regression analyses, group status (ASz vs. TD) significantly predicted scores on the general intelligence, verbal memory, working memory, and EF-inhibition domains (p<0.05). The severity of problems on each of the individual antecedents comprising the antecedent triad did not relate strongly to performance on the neurocognitive domains.
CONCLUSIONS:
Children aged 9-12 years who present multiple antecedents of schizophrenia display poorer neurocognition than healthy peers on several domains showing pronounced deficits in schizophrenia, first-episode psychosis, and youth with prodromal symptoms. Longitudinal follow-up is necessary to determine the extent to which poorer neurocognitive performance is specific to those who develop schizophrenia.
Accessibility: Document exists in file (previous version submitted for publication)
Copyright/Reproduction:
By permission
Language:
eng
Author:
Cullen, A. E.
Secondary author(s):
Dickson, H., West, S. A., Morris, R., Mould, G. L., Hodgins, S., Murray, R., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Reference:
Cullen, A. E., Dickson, H., West, S. A., Morris, R., Mould, G. L., Hodgins, S., Murray, R., & Laurens, K. R. (2010). Neurocognitive performance in children aged 9 – 12 years who present putative antecedents of schizophrenia. Schizophrenia Research, 121(1-3), 15-23. https://doi.org/10.1016/j.schres.2010.05.034
2-year Impact Factor: 4.374|2010
Times cited: 34|2025-02-07
Indexed document: Yes
Quartile: Q1
Keywords: High-risk / Psychosis / Intelligence / Executive function / Memory / Scholastic achievement

Neurocognitive performance in children aged 9 – 12 years who present putative antecedents of schizophrenia

Neurocognitive performance in children aged 9 – 12 years who present putative antecedents of schizophrenia
DocumentDissociation of local/global visual preference and performance in Williams Syndrome2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-094
Location: Arquivo PCA - Pasta 21/2006
Title:
094 - Feedback modulation of visual processing by limbic circuits: A functional connectivity approach to visual face processing
Duration: 2008-01 - 2011-02
Researcher(s):
Miguel Castelo-Branco, Cristina Januário, Solange Silva, Aldina Reis, Catarina Mateus, Miguel Cordeiro
Institution(s): IBILI - Faculdade de Medicina, Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Januário, C., Silva, S., Mateus, C., Cordeiro, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function / Emotion / Body structure and function / Vision

Reference code: PT/FB/BL-2006-094.16
Location: Arquivo PCA - Pasta 21/2006
Title:
Dissociation of local/global visual preference and performance in Williams Syndrome
Publication year: 2009
URL:
http://journals.cambridge.org/download.php?file=%2FINS%2FINS15_S2%2FS1355617709991044a.pdf&code=0fad4d8df994926de051a6bcc1b17fc3
Abstract/Results: ABSTRACT:
OBJECTIVE:
Williams syndrome (WS) is characterized by visuospatial impairment often described as reflecting a local processing bias. However, these evidences are controversial, which may also be compounded by the large variability in performance that has been found across studies. To investigate local processing bias in WS and define whether this bias determines performance in global-local tasks.
PARTICIPANTS AND METHODS:
A preference task (match to sample similarity) and a performance task (requiring identification of local or global similarity) were conducted in 15 WS subjects using Navon hierarchical figures. Performance of WS group was compared to a chronological (n=15) and mental age-matched control group (n=15).
RESULTS:
The preference task demonstrated that 7 WS subjects showed a local bias, while 9 subjects performed like controls, exhibiting a global preference. Performance on the preference task was significantly correlated with education level and intelligence level. In the performance task WS subjects with a local processing bias made significantly more errors in the global condition than the WS subjects with a global preference.
CONCLUSIONS:
Our results suggest that the local bias is not homogeneous across WS subjects, thus reflecting the great variability described in other studies. By comparing WS subjects with a global bias to WS subjects with a local bias, we showed that the education level and the level of intelligence are important factors in defining the processing style. Additionally, the local processing preference found in some WS subjects seems to be related to their global processing deficit, both being commonly correlated with the education level.
Accessibility: Document does not exist in file
Language:
eng
Author:
Bernardino, I.
Secondary author(s):
Van Asselen, M., Castelo-Branco, M.
Document type:
Abstract
Number of reproductions:
1
Reference:
Bernardino, I., Van Asselen, M., & Castelo-Branco, M. (2009). Dissociation of local/global visual preference and performance in Williams Syndrome. Journal of the International Neuropsychological Society, 15(Suppl. 2), 68. https://doi.org/10.1017/S1355617709991044
Indexed document: Yes
Keywords: Williams syndrome / Local processing bias / Education level / Intelligence

Dissociation of local/global visual preference and performance in Williams Syndrome

Dissociation of local/global visual preference and performance in Williams Syndrome
DocumentCognitive impairment among children at-risk for schizophrenia2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2006-035.23
Location: Arquivo PCA - Pasta 17/2006
Title:
Cognitive impairment among children at-risk for schizophrenia
Publication year: 2014
URL:
http://www.sciencedirect.com/science/article/pii/S0022395613003695
Abstract/Results: ABSTRACT:
Adults with schizophrenia present cognitive impairments, as do individuals at ultra-high risk for the disorder, youth with relatives with schizophrenia spectrum disorders, and children with antecedents of schizophrenia. The present study aimed to determine if impairments in childhood differed depending on the definition of risk and/or on the degree of relatedness to an affected individual, and if impairments were explained by IQ. Four groups of children aged 9–12 years were studied: (1) 13 children with =1 first-degree or =2 second-degree affected relatives (high familial loading: FHxH); (2) 14 with =1 affected second-degree relative (lower familial loading: FHxL); (3) 32 with well-replicated antecedents of schizophrenia (ASz); and (4) 45 typically-developing (TD) children with neither a positive family history nor antecedents. Compared to TD children, both FHxH and ASz children exhibited significantly poorer verbal comprehension, scholastic achievement, and verbal working memory, while FHxH children additionally displayed significantly lower full-scale IQ, and verbal memory and executive function impairments. After adjusting statistical analyses for IQ, group differences were attenuated. Relative to TD children, FHxL children showed no significant differences in performance. The results imply that impairments in verbal comprehension, scholastic achievement, and verbal working memory may index vulnerability for schizophrenia among children with affected relatives with the disorder and among those with multiple antecedents of the disorder who have no affected relatives. More accurate identification of children at-risk for schizophrenia and the specific deficits that they present provides opportunities for interventions such as cognitive remediation that may impact the development of the illness.
Accessibility: Document does not exist in file
Language:
eng
Author:
Dickson, H.
Secondary author(s):
Cullen, A. E., Reichenberg, A., Hodgins, S., Campbell, D. D., Morris, R., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Reference:
Dickson, H., Cullen, A. E., Reichenberg, A., Hodgins, S., Campbell, D. D., Morris, R. G., & Laurens, K. R. (2014). Cognitive impairment among children at-risk for schizophrenia. Journal of Psychiatric Research, 50, 92-99. https://doi.org/10.1016/j.jpsychires.2013.12.003
2-year Impact Factor: 3.957|2014
Times cited: 34|2025-02-10
Indexed document: Yes
Quartile: Q1
Keywords: Intelligence / Psychosis / Risk factors / Genetic liability / Developmental psychopathology / Psychotic-like experiences
DocumentTrajectories of cognitive development during adolescence among youth at-risk for schizophrenia2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

Reference code: PT/FB/BL-2012-194.11
Location: Arquivo PCA - Pasta 25/2012
Title:
Trajectories of cognitive development during adolescence among youth at-risk for schizophrenia
Publication year: 2018
URL:
https://onlinelibrary.wiley.com/doi/full/10.1111/jcpp.12912
Abstract/Results: ABSTRACT:
BACKGROUND:
Among adults with schizophrenia, evidence suggests that premorbid deficits in different cognitive domains follow distinct developmental courses during childhood and adolescence. The aim of this study was to delineate trajectories of adolescent cognitive functions prospectively among different groups of youth at-risk for schizophrenia, relative to their typically developing (TD) peers.
METHOD:
Using linear mixed models adjusted for sex, ethnicity, parental occupation and practice effects, cognitive development between ages 9 and 16 years was compared for youth characterised by a triad of well-replicated developmental antecedents of schizophrenia (ASz; N = 32) and youth with a least one affected relative with schizophrenia or schizoaffective disorder (FHx; N = 29), relative to TD youth (N = 45). Participants completed measures of IQ, scholastic achievement, memory and executive function at three time-points, separated by approximately 24-month intervals.
RESULTS:
Compared to TD youth, both ASz and FHx youth displayed stable developmental deficits in verbal working memory and inhibition/switching executive functions. ASz youth additionally presented with stable deficits in measures of vocabulary (IQ), word reading, numerical operations, and category fluency executive function, and a slower rate of growth (developmental lag) on spelling from 9 to 16 years than TD peers. Conversely, faster rates of growth relative to TD peers (developmental delay) were observed on visual and verbal memory, and on category fluency executive function (ASz youth only) and on matrix reasoning (IQ) and word reading (FHx youth only).
CONCLUSIONS:
These differential patterns of deviation from normative adolescent cognitive development among at-risk youth imply potential for cognitive rehabilitation targeting of specific cognitive deficits at different developmental phases.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Dickson, H.
Secondary author(s):
Cullen, A. E., Jones, R., Reichenberg, A., Roberts, R. E., Hodgins, S., Morris, R. G., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Reference:
Dickson, H., Cullen, A. E., Jones, R., Reichenberg, A., Roberts, R. E., Hodgins, S., Morris, R. G., & Laurens, K. R. (2018). Trajectories of cognitive development during adolescence among youth at-risk for schizophrenia. Journal of Child Psychology and Psychiatry, 59(11), 1215-1224. https://doi.org/10.1111/jcpp.12912
2-year Impact Factor: 3.593|2018
Times cited: 22|2025-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Psychosis / Academic performance / Executive function / Intelligence / Memory
DocumentThe development of cognitive and emotional processing as reflected in children’s dreams: Active self in an eventful dream signals better neuropsychological skills2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-055
Location: Arquivo PCA - Pasta 11/2010
Title:
055 - The developmental and psychophysiological emergence of dreams and nightmares: state-dependent and state-independent fronto-cortical disconnectivity
Duration: 2011-03 - 2014-02
Researcher(s):
Róbert Bódizs, Peter Daniel Simor, Piroska Sándor, Szilvia Csóka, Klára Horváth
Institution(s): Institute of Behavioural Sciences, Semmelweis University, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final reports
7 Articles ( published or submittedr publication)
5 Conference abstracts
Language: eng
Author:
Bódizs, R.
Secondary author(s):
Simor, P., Sándor, P., Csóka, S., Horváth, K.
Number of reproductions:
1
Keywords:
Psychophysiology / Sleep and Dreams / Biopsychological problems / Mental health / Sleep disorders / Brain structure and function / Developmental psychology

Reference code: PT/FB/BL-2010-055.17
Location: Arquivo PCA - Pasta 10/2010
Title:
The development of cognitive and emotional processing as reflected in children’s dreams: Active self in an eventful dream signals better neuropsychological skills
Publication year: 2016
URL:
http://psycnet.apa.org/record/2016-13720-006
Abstract/Results: ABSTRACT:
The development of dreaming and its association with brain maturation and cognitive development are rarely studied in spite of adult studies showing a close relationship between dreaming and cognitive functioning. In order to bridge this gap in the literature we aimed to depict the associations between individual differences in neurocognitive maturation and the formal and content related characteristics of children’s dream reports. We analyzed the dream reports of 40 children between the ages of 4 to 8 years. Specific dream content categories, found to change significantly throughout development, were correlated with cognitive performance. To measure the latter we used neuropsychological tests (a modified version of the Fruit Stroop Test and Emotional Stroop Test for Children, and the Attention Network Test [ANT]) and intelligence tests (subscales of the Wechsler Intelligence Scale for Children [WISC–IV], and the Raven’s Colored Progressive Matrices [CPM]). Results suggest that the dreamer’s presence in their dreams (manifested in activities, interactions, self-effectiveness, willful effort, and cognitive reflections) indicates more effective executive control in waking life. The quality and content of these activities and interactions are correlated with the child’s capacities of emotional processing. Contrary to previous findings dream bizarreness and dream recall frequency were not associated with any cognitive indicators. Although in adult dream research the continuity of waking and dreaming cognition has been well-studied, our work is 1 of the first to explore the connection between children’s cognitive maturation and dreaming.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Sándor, P.
Secondary author(s):
Szakadát, S., Bódizs, R.
Document type:
Article
Number of reproductions:
1
Reference:
Sándor, P., Szakadát, S., & Bódizs, R. (2016). The development of cognitive and emotional processing as reflected in children’s dreams: Active self in an eventful dream signals better neuropsychological skills. Dreaming, 26(1), 58-78. https://doi.org/10.1037/drm0000022
2-year Impact Factor: 0.867|2016
Times cited: 10|2025-02-11
Indexed document: Yes
Quartile: Q3
Keywords: Dreams / Cognitive development / Maturation / Intelligence / Executive functions
DocumentHumans learning a complex task are picky and sticky2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-360
Location: BF-GMS
Title:
360 - Dissecting dynamical components of complex decision-making using a computer game-based task
Duration: 2019-01 - 2025-01
Researcher(s):
Gautam Agarwal, Zachary Mainen, Alfonso Renart, Mattia Bergomi
Institution(s): Champalimaud Centre for the Unknown, Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Agarwal, G.
Secondary author(s):
Mainen, Z., Renart, A., Bergomi, M.
Number of reproductions:
1
Keywords:
Big Data / Planning / Strategy / Skill learning / Psychophysiology

Reference code: PT/FB/BL-2018-360.02
Location: BF-GMS
Title:
Humans learning a complex task are picky and sticky
Publication year: 2022
URL:
https://2022.ccneuro.org/proceedings/0000670.pdf
Abstract/Results: ABSTRACT:
While neural networks approach human levels of perfor- mance in many complex tasks, they require much more training than humans. This may be because only humans can infer and apply generalizable principles from prior ex- perience (Lake, Ullman, Tenenbaum, & Gershman, 2017). However, the statistics that underlie the human learning process are poorly understood and hard to investigate in the large state spaces found in most complex tasks (van Opheusden & Ma, 2019). We thus designed a cog- nitive task whose potential solutions are few enough for subjects to densely sample policy space, but complex enough to compel intelligent search. We launched the game as a smartphone-based app (hexxed.io) to collect data from 10k human participants. We find that unlike re- inforcement learning agents (Deep-Q Networks ; DQNs), humans (1) search a highly restricted subset of the pol- icy space; (2) attempt even poor solutions many times before discarding them; (3) arrive at the optimal policy suddenly and unpredictably with a “leap of insight”. Our data suggest a “top-down” learning process by which hu- mans propose explanatory solutions which they replace only upon collecting sufficient evidence to the contrary, in contrast to the “bottom-up” learning of DQNs that as- sociates states with rewarding actions
Accessibility: Document exists in file
Language:
eng
Author:
Quendera, T.
Secondary author(s):
Deng, D., Hamidi, M., Bergomi, M., Mainen, Z. F., Agarwal, G.
Document type:
Conference paper
Number of reproductions:
1
Reference:
Quendera, T., Deng, D., Hamidi, M., Bergomi, M., Mainen, Z. F., & Agarwal, G. (2022). Humans learning a complex task are picky and sticky. 2022 Conference on Cognitive Computational Neuroscience. https://doi.org/10.32470/CCN.2022.1277-0
Indexed document: No
Keywords: Problem solving / Search / Intelligence / Skill learning / Decision making / Epiphany

Humans learning a complex task are picky and sticky

Humans learning a complex task are picky and sticky
DocumentFinal report - Dissecting dynamical components of complex decision-making using a computer game-based task2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-360
Location: BF-GMS
Title:
360 - Dissecting dynamical components of complex decision-making using a computer game-based task
Duration: 2019-01 - 2025-01
Researcher(s):
Gautam Agarwal, Zachary Mainen, Alfonso Renart, Mattia Bergomi
Institution(s): Champalimaud Centre for the Unknown, Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Agarwal, G.
Secondary author(s):
Mainen, Z., Renart, A., Bergomi, M.
Number of reproductions:
1
Keywords:
Big Data / Planning / Strategy / Skill learning / Psychophysiology

Reference code: PT/FB/BL-2018-360.01
Location: BF-GMS
Title:
Final report - Dissecting dynamical components of complex decision-making using a computer game-based task
Publication year: 2024
Abstract/Results:
ABSTRACT:
Background
Learning a complex skill requires searching a potentially enormous search space. While artificial intelligence (AI) can now approach human levels of performance in many complex tasks, they require much more training than humans. This may be because only humans can infer and apply generalizable principles from limited experiences. However, the statistics that underlie this learning process are both poorly understood and hard to investigate in the large state spaces found in most complex tasks.
Aims
Our goal is to design a cognitive task that is simple enough to study using the tools of psychophysics, but complex enough to induce intelligent search. We aim to define the statistical principles that shape efficient search to improve models of natural and artificial intelligence.
Method
We designed a puzzle with minimal verbal instruction and thousands of potential solutions, only a few of which meet the criterion of success. We launched the game as a smartphone-based app (hexxed.io), allowing us to collect data from ~10k human participants and compared their learning to artificial neural networks (ANNs). We analysed pupil dynamics to reveal how subjects plan.
Results
Unlike the AI, humans 1) search a highly restricted subset of the policy space; 2) attempt even poor solutions many times before discarding them; 3) arrive at the optimal policy suddenly and unpredictably with a “leap of insight”. 4) plan more for trials with longer reaction times, as revealed by greater pupil movement.
Conclusions
Our data suggest a “top-down” learning process in which people learn by proposing explanatory theories which they refine or replace only upon collecting sufficient evidence to the contrary.
Accessibility: Document exists in file
Language:
eng
Author:
Agarwal, G.
Secondary author(s):
Hamidi, M., Deng, D., Quendera, T., Bergomi, M., Mainen, Z.
Document type:
Final report
Number of reproductions:
1
Reference:
Agarwal, G., Hamidi, M., Deng, D., Quendera, T., Bergomi, M., & Mainen, Z. (2024). Final report - Dissecting dynamical components of complex decision-making using a computer game-based task.
Indexed document: No
Keywords: Problem solving / Intelligence / Skill learning / Decision making / Epiphany

Final report - Dissecting dynamical components of complex decision-making using a computer game-based task

Final report - Dissecting dynamical components of complex decision-making using a computer game-based task