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DocumentPhysiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis2005

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1998
Location: Arquivo PCA - Pastas 1 a 11/1998
Title:
1998 Grants
Start date: 1999-01 - 2005-12
Dimension/support:
11 caixas de arquivo

Reference code: PT/FB/BL-1998-030
Location: Arquivo PCA - Pasta 9/1998
Title:
030 - Caracterização neurofisiológica e psicofisiológica de disfunções cerebrais utilizando estudos qEEG/ERP. Metodologia e aplicações
Duration: 1999-06 - 2004-04
Researcher(s):
António Martins da Silva, Denisa Maria Vasques Mendonça, João Manuel Carmona Ferreira Lopes, Maria Regina Pinto Brito Aguiar Andrade, João Eduardo Paiva Ramalheira, João Paulo Trigueiros Silva Cunha, Miguel Oliveira e Silva, Teresa Temudo, Óscar Gomes, Óscar Alves
Institution(s): Hospital Sto. António, Porto (Portugal)
Language: por
Author:
Martins da Silva, A.
Secondary author(s):
Mendonça, D., Lopes, J., Andrade, M., Ramalheira, J., Cunha, J., Silva, M. O., Temudo, T., Gomes, Ó., Alves, Ó.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Brain dysfunction

Reference code: PT/FB/BL-1998-030.02
Location: Arquivo PCA - Pasta 9/1998
Title:
Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis
Publication year: 2005
URL:
http://www.neurologia.es/sec/deAutor.php?auof=586&i=e#
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=125&SID=V1leIhH4ysTdNpr3OrX&page=1&doc=1
Accessibility: Document exists in file (Portuguese version)
Copyright/Reproduction:
By permission
Language:
spa
Author:
Vilhena, E.
Secondary author(s):
Paiva, I., Rodrigues, H., Martins da Silva, A., Mendonça, D.
Document type:
Article
Number of reproductions:
1
Reference:
Vilhena, E., Paiva, I., Rodrigues, H., Martins da Silva, A., & Mendonça, D. (2005). Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis. Revista de Neurologia, 41(10), 633-635.
2-year Impact Factor: 0.391|2005
Times cited: 0|2025-09-09
Indexed document: Yes
Quartile: Q4
Keywords: P300 / Brain function / Amplitude / Latency / Cognitive potentials / Evoked potentials / Analysis of variance with repeated measures

Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis

Physiological variations in ERP300 auditory brain potentials in young adults. A sequential analysis
DocumentAnálise quantitativa dos potenciais cerebrais ERP300 em adultos jovens2003

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1998
Location: Arquivo PCA - Pastas 1 a 11/1998
Title:
1998 Grants
Start date: 1999-01 - 2005-12
Dimension/support:
11 caixas de arquivo

Reference code: PT/FB/BL-1998-030
Location: Arquivo PCA - Pasta 9/1998
Title:
030 - Caracterização neurofisiológica e psicofisiológica de disfunções cerebrais utilizando estudos qEEG/ERP. Metodologia e aplicações
Duration: 1999-06 - 2004-04
Researcher(s):
António Martins da Silva, Denisa Maria Vasques Mendonça, João Manuel Carmona Ferreira Lopes, Maria Regina Pinto Brito Aguiar Andrade, João Eduardo Paiva Ramalheira, João Paulo Trigueiros Silva Cunha, Miguel Oliveira e Silva, Teresa Temudo, Óscar Gomes, Óscar Alves
Institution(s): Hospital Sto. António, Porto (Portugal)
Language: por
Author:
Martins da Silva, A.
Secondary author(s):
Mendonça, D., Lopes, J., Andrade, M., Ramalheira, J., Cunha, J., Silva, M. O., Temudo, T., Gomes, Ó., Alves, Ó.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Brain dysfunction

Reference code: PT/FB/BL-1998-030.05
Location: Arquivo PCA - Pasta 9/1998
Title:
Análise quantitativa dos potenciais cerebrais ERP300 em adultos jovens
Publication year: 2003
URL:
http://hdl.handle.net/10216/12952
Abstract/Results: ABSTRACT:
The integration in a multidisciplinary team in the "Serviço de Neurofisiologia do Hospital Geral de Santo António do Porto" enabled the contribution in one of the research lines that a is to study procedures to quantify Cerebral Activity. The study of long latency potentials is a method of investigation of the Central Nervous System, especially on the cognitive information processing. The discrimination of a random stimulus in a sequence of auditory rhythmic stimulus generates a potential whose basic wave is the P300 (or ERP300). We tested if the amplitude and the latency of the ERP300, determined in scalp, keep their general characteristics overtime, analysing the variations in terms of place, when sequentially determined, at fixed intervals of time, in young adults and in stable situations. We used the oddball paradigm to generate the ERP300, stimulated by a set of 50 stimulus. The potentials were registered on the scalp (Fz, Cz, C3 and C4). We have studied 30 healthy subjects (not taking drugs). Each subject was studied each time in two different trials. The record was repeated in the same day (morning and afternoon) within a six-hour interval. The same procedure was repeated, under the same conditions, one week later. The analysis of data fulfilled using an Analysis of Variance of Repeated Measures. We find variations statistically significative in terms of the place in the scalp for the latency and the amplitude of the ERP300. It was verified that the amplitude of the first trial is always greater than to the second. The stimulation is earlier recognized in Cz. ERP300 response was attenuated with test repetition.
Relatively to the sex its main effect did not show statistically significant differences. Thus, this analysis allowed us to assume that there is no evidence to reject the ERP 300 stability over time, suggesting individual stability of the answers of the ERP300.
In contrast to the ERPs, there are dynamic changes in the spontaneous EEG, which are also related to an event, considered as induced des- or syncronization of the cerebral activity (ERD/ERS).
Therefore, the study's aim was to test the cerebral activity in various places of the scalp, bearing in mind non-synchronisation (ERD)/synchronisation (ERS), and to define temporal spaces in ordinary subjects for further comparison with groups with diverse pathologies. Our contribution was based on the establishment of the protocol of acquisition of data and methodology of preparation and validation of data for analysis.
The Model of Analysis of Variance of Repeated Measures has had far reaching applications in the study of the Cerebral Activity analysis. Therefore, it will be used in future analyses that we will elaborate for Quantification of Cerebral Activity, namely in the analysis of desynchronization(ERD)/synchronization(ERS) the EEG signal. This work contains a brief description of statistical models of Analysis of Variance and a discussion of the statistical models as well as their respective assumptions.
Accessibility: Document does not exist in file
Language:
por
Author:
Vilhena, E.
Document type:
Master's thesis
Number of reproductions:
1
Reference:
Vilhena, E. (2003). Análise quantitativa dos potenciais cerebrais ERP300 em adultos jovens (Master´s thesis, Faculdade de Engenharia - Universidade do Porto, Portugal). Retrieved from: http://hdl.handle.net/10216/12952
Indexed document: No
Keywords: P300 / Latency / Amplitude / Evoked potentials / Event-related desynchronization (ERD) / Event-related synchronization (ERS)
DocumentThe P300 signal is monotonically modulated by target saliency level irrespective of the visual feature domain2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-094
Location: Arquivo PCA - Pasta 21/2006
Title:
094 - Feedback modulation of visual processing by limbic circuits: A functional connectivity approach to visual face processing
Duration: 2008-01 - 2011-02
Researcher(s):
Miguel Castelo-Branco, Cristina Januário, Solange Silva, Aldina Reis, Catarina Mateus, Miguel Cordeiro
Institution(s): IBILI - Faculdade de Medicina, Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Januário, C., Silva, S., Mateus, C., Cordeiro, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function / Emotion / Body structure and function / Vision

Reference code: PT/FB/BL-2006-094.27
Location: Arquivo PCA - Pasta 21/2006
Title:
The P300 signal is monotonically modulated by target saliency level irrespective of the visual feature domain
Publication year: 2010
URL:
http://onlinelibrary.wiley.com/doi/10.1111/j.1755-3768.2010.4325.x/abstract
Abstract/Results: ABSTRACT:
PURPOSE:
Event related responses to infrequent and task-relevant stimuli often include an attentional peak, the P300 component. This component is typically regarded as independent from the sensory modality, with amplitude depending on target occurrence probability. In this study, we investigated whether the P300 signal could similarly be modulated by the degree of perceptual difference across visual target properties.
METHODS:
We used an oddball block design with texture and colour as perceptual category features and a frequency ratio of 1:16. EEG/ERP responses were recorded from 68 channels in 9 healthy participants, matched for age and educational level. For the colour condition, 3 targets with increasing steps of categorical deviation in perceived redness from the standard stimulus were used. Concerning the texture segmentation condition, 3 targets with increasing spatial phase difference were chosen. Colour target patches were presented against a reference background of a standard additive primary red patch, and texture patches against a standard grating one with no phase segregation contrast.
RESULTS:
Repeated measure analysis results suggest a significant modulation of P300 amplitude target levels in midline central and parietal channels for both conditions. Significant Spearman correlations (positive with amplitude and negative with latency) support this order effect between target perceptual level and the P300 response.
CONCLUSION:
We conclude that the amplitude and latency of the P300 response is monotonically modulated by saliency levels of distinct target categories.
Accessibility: Document does not exist in file
Language:
eng
Author:
Teixeira, M.
Secondary author(s):
Castelo-Branco, M., Nascimento, S., Almeida, V.
Document type:
Abstract
Number of reproductions:
1
Reference:
Teixeira, M., Castelo-Branco, M., Nascimento, S., Almeida, V. (2010). The P300 signal is monotonically modulated by target saliency level irrespective of the visual feature domain. Acta Ophthalmologica, 88(Suppl. s246). https://doi.org/10.1111/j.1755-3768.2010.4325.x
Indexed document: Yes
Keywords: P300 / Amplitude / Latency / Saliency / Visual stimulus features
DocumentTime-delay latency of resting-state blood oxygen level-dependent signal related to the Level of consciousness in patients with severe consciousness impairment2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-53
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Time-delay latency of resting-state blood oxygen level-dependent signal related to the Level of consciousness in patients with severe consciousness impairment
Publication year: 2020
URL:
https://www.liebertpub.com/doi/abs/10.1089/brain.2019.0716
Abstract/Results: ABSTRACT:
Recent evidence on resting-state functional magnetic resonance imaging (rs-fMRI) suggests that healthy human brains have a temporal organization represented in a widely complex time-delay structure. This structure seems to underlie brain communication flow, integration/propagation of brain activity, as well as information processing. Therefore, it is probably linked to the emergence of highly coordinated complex brain phenomena, such as consciousness. Nevertheless, possible changes in this structure during an altered state of consciousness remain poorly investigated. In this work, we hypothesized that due to a disruption in high-order functions and alterations of the brain communication flow, patients with disorders of consciousness (DOC) might exhibit changes in their time-delay structure of spontaneous brain activity. We explored this hypothesis by comparing the time-delay projections from fMRI resting-state data acquired in resting state from 48 patients with DOC and 27 healthy controls (HC) subjects. Results suggest that time-delay structure modifies for patients with DOC conditions when compared with HC. Specifically, the average value and the directionality of latency inside the midcingulate cortex (mCC) shift with the level of consciousness. In particular, positive values of latency inside the mCC relate to preserved states of consciousness, whereas negative values change proportionally with the level of consciousness in patients with DOC. These results suggest that the mCC may play a critical role as an integrator of brain activity in HC subjects, but this role vanishes in an altered state of consciousness.
Accessibility: Document does not exist in file
Language:
eng
Author:
Rudas, J.
Secondary author(s):
Martínez, D., Castellanos, G. , Demertzi, A. , Martial, C. , Carriére, M., Aubinet, C. , Soddu, A. , Laureys, S. , Gómez, F.
Document type:
Article
Number of reproductions:
3
Reference:
Rudas, J., Martínez, D., Castellanos, G., Demertzi, A., Martial, C., Carriére, M., ... Gómez, F. (2020). Time-delay latency of resting-state blood oxygen level-dependent signal related to the Level of consciousness in patients with severe consciousness impairment. Brain Connectivity, 10(2), 83-94. https://doi.org/10.1089/brain.2019.0716
2-year Impact Factor: 2.262|2020
Times cited: 10|2025-09-18
Indexed document: Yes
Quartile: Q4
Keywords: Disorders of consciousness / Functional connectivity / Latency / Midcingulate cortex / Resting-state networks / Time delay