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DocumentChanges in mismatch negativity across pre-hypnosis, hypnosis and post-hypnosis conditions distinguish high from low hypnotic susceptibility groups2005

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-061
Location: Arquivo PCA - Pasta 5/2000
Title:
061 - Changes in mismatch negativity during hypnosis as an indicator of susceptibility to both hypnosis and to paranormal experiences
Duration: 2001-01 - 2002-03
Researcher(s):
John Howard Gruzelier, Graham Jamieson
Institution(s): Imperial College School of Medicine, London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Final report
Language: eng
Author:
Gruzelier, J. H.
Secondary author(s):
Jamieson, G.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Altered states of consciousness / Hypnosis / Personality factors / Anomalous cognition/experiences / Brain structure and function

Reference code: PT/FB/BL-2000-061.04
Location: Arquivo PCA - Pasta 5/2000
Title:
Changes in mismatch negativity across pre-hypnosis, hypnosis and post-hypnosis conditions distinguish high from low hypnotic susceptibility groups
Publication year: 2005
URL:
http://www.ncbi.nlm.nih.gov/pubmed/16182937
Contents: http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=105&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
The role of alterations in mismatch negativity (MMN) in hypnosis was examined by recording MMN of the auditory ERP at frontal (F3, Fz, and F4) and mastoid (M1 and M2) placements. Frontal MMN is believed to reflect activity in right anterior cortical generators, whereas MMN at mastoid leads reflects generators located bilaterally in the temporal auditory cortex. MMN recordings were obtained in 11 low and 12 high hypnotically susceptible participants in three successive blocks; pre-hypnosis, hypnosis and post-hypnosis. Frontal (but not temporal) MMN showed a significant quadratic trend across testing conditions. It increased during hypnosis and then dropped post-hypnosis for both susceptibility groups. Linear trends for frontal and temporal MMN showed directly opposite patterns of change in the interaction between hypnotic susceptibility and testing blocks. Frontal MMN built up linearly over the test blocks in high relative to low susceptibility participants. Temporal MMN showed the reverse pattern and increased linearly across test conditions in those with low relative to high hypnotic susceptibility.
Accessibility: Document does not exist in file
Language:
eng
Author:
Jamieson, G.
Secondary author(s):
Dwivedi, P., Gruzelier, J. H.
Document type:
Article
Number of reproductions:
3
Reference:
Jamieson, G., Dwivedi, P., & Gruzelier, J. H. (2005). Changes in mismatch negativity across pre-hypnosis, hypnosis and post-hypnosis conditions distinguish high from low hypnotic susceptibility groups. Brain Research Bulletin, 67(4), 298-303. https://doi.org/10.1016/j.brainresbull.2005.06.033
2-year Impact Factor: 2.481|2005
Times cited: 15|2025-09-09
Indexed document: Yes
Quartile: Q2
Keywords: Hypnosis / Hypnotic susceptibility / Mismatch negativity (MMN) / Roving standard / Frontal mismatch negativity (MMN) / Temporal mismatch negativity MMN

Changes in mismatch negativity across prehypnosis, hypnosis and post-hypnosis conditions distinguish high from low hypnotic susceptibility groups

Changes in mismatch negativity across prehypnosis, hypnosis and post-hypnosis conditions distinguish high from low hypnotic susceptibility groups
DocumentFinal report - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.01
Location: Arquivo PCA - Pasta 2/2010
Title:
Final report - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Publication year: 2013
URL:
http://www.bial.com/imagem/Bolsa3710.pdf
Abstract/Results: RESULTS:
The goal of the present project was to demonstrate that novelty detection is a basic principle of the functional organization of the auditory system, expanding from lower levels along the auditory pathway in the brainstem up to higher-order areas of the cerebral cortex. As novelty detection requires the modelling of regularity in the acoustic environment, we go beyond by proposing that increasing levels of complexity in acoustic regularity will be encoded in higher levels of the auditory system’s hierarchy. Traditionally, auditory novelty detection has been studied by means of the mismatch negativity (MMN) event-related brain potential, generated in the auditory cortex with a latency of about 100-150 ms. In the present project, we found that auditory stimuli differing in intensity or in location from the preceding acoustic regularity not only elicited the MMN but much earlier deviance-related correlates, by the Na for location and by the Na-Pa transition for intensity changes, respectively. These effects occurred only at 20-30 ms from change onset, revealing that deviance detection is a pervasive property of the auditory system. Moreover, as the experiments were appropriately controlled, so that deviant stimuli were compared to identical low probability stimuli but occurring on a context of other low probability stimuli, the results support a mechanism of regularity encoding for deviance detection. Also, we proposed a model where much more complex types of regularity would be encoded higher up in the auditory hierarchy yielding change-related effects only by the latency window of the MMN.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Cognitive neuroscience / Auditory neuroscience / Auditory novelty detection / Mismatch negativity (MMN)

Final report - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain

Final report - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
DocumentFast detection of unexpected sound intensity decrements as revealed by human evoked potentials2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.02
Location: Arquivo PCA - Pasta 2/2010
Title:
Fast detection of unexpected sound intensity decrements as revealed by human evoked potentials
Publication year: 2011
URL:
http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pone.0028522&representation=PDF
Abstract/Results: ABSTRACT:
The detection of deviant sounds is a crucial function of the auditory system and is reflected by the automatically elicited mismatch negativity (MMN), an auditory evoked potential at 100 to 250 ms from stimulus onset. It has recently been shown that rarely occurring frequency and location deviants in an oddball paradigm trigger a more negative response than standard sounds at very early latencies in the middle latency response of the human auditory evoked potential. This fast and early ability of the auditory system is corroborated by the finding of neurons in the animal auditory cortex and subcortical structures, which restore their adapted responsiveness to standard sounds, when a rare change in a sound feature occurs. In this study, we investigated whether the detection of intensity deviants is also reflected at shorter latencies than those of the MMN. Auditory evoked potentials in response to click sounds were analyzed regarding the auditory brain stem response, the middle latency response (MLR) and the MMN. Rare stimuli with a lower intensity level than standard stimuli elicited (in addition to an MMN) a more negative potential in the MLR at the transition from the Na to the Pa component at circa 24 ms from stimulus onset. This finding, together with the studies about frequency and location changes, suggests that the early automatic detection of deviant sounds in an oddball paradigm is a general property of the auditory system.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Althen, H.
Secondary author(s):
Grimm, S., Escera, C.
Document type:
Article
Number of reproductions:
1
Reference:
Althen, H., Grimm, S., & Escera, C. (2011). Fast detection of unexpected sound intensity decrements as revealed by human evoked potentials. PLoS ONE, 6(12), e28522. https://doi.org/10.1371/journal.pone.0028522
2-year Impact Factor: 4.092|2011
Times cited: 54|2025-09-10
Indexed document: Yes
Quartile: Q1
Keywords: Mismatch negativity (MMN) / Auditory system / Deviant sounds

Fast detection of unexpected sound intensity decrements as revealed by human evoked potentials

Fast detection of unexpected sound intensity decrements as revealed by human evoked potentials
DocumentAuditory deviance detection revisited: Evidence for a hierarchical novelty system2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.04
Location: Arquivo PCA - Pasta 2/2010
Title:
Auditory deviance detection revisited: Evidence for a hierarchical novelty system
Publication year: 2012
URL:
http://www.sciencedirect.com/science/article/pii/S0167876011001747
Abstract/Results: ABSTRACT:
The fast detection of novel or deviant stimuli is a striking property of the auditory processing which reflects basic organizational principles of the auditory system and at the same time is of high practical significance. In human electrophysiology, deviance detection has been related to the occurrence of the mismatch negativity (MMN) — a component of the event-related potential (ERP) evoked 100 to 250 ms after the occurrence of a rare irregular sound. Recently, it has been shown in animal studies that a considerable portion of neurons in the auditory pathway exhibits a property called stimulus-specific adaptation enabling them to encode inter-sound relationships and to discharge at higher rates to rare changes in the acoustic stimulation. These neural responses have been linked to the deviant-evoked potential measured at the human scalp, but such responses occur at lower levels anatomically (e.g. the primary auditory cortex as well as the inferior colliculi) and are elicited earlier (20–30 ms after sound onset) in comparison to MMN. Further, they are not considerable enough in size to be interpreted as a direct neural correlate of the MMN. We review here a series of recent findings that provides a first step toward filling this gap between animal and human recordings by showing that comparably early modulations due to a sound's deviancy can be observed in humans, particularly in the middle-latency portion of the ERP within the first 50 ms after sound onset. The existence of those early indices of deviance detection preceding the well-studied MMN component strongly supports the idea that the encoding of regularities and the detection of violations is a basic principle of human auditory processing acting on multiple levels. This sustains the notion of a hierarchically organized novelty and deviance detection system in the human auditory system.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Grimm, S.
Secondary author(s):
Escera, C.
Document type:
Article
Number of reproductions:
1
Reference:
Grimm, S., & Escera, C. (2012). Auditory deviance detection revisited: Evidence for a hierarchical novelty system. International Journal of Psychophysiology, 85(1), 88-92. https://doi.org/10.1016/j.ijpsycho.2011.05.012
2-year Impact Factor: 2.036|2012
Times cited: 116|2025-09-10
Indexed document: Yes
Quartile: Q3
Keywords: Auditory system / Deviance detection / Mismatch negativity (MMN)

Auditory deviance detection revisited: Evidence for a hierarchical novelty system

Auditory deviance detection revisited: Evidence for a hierarchical novelty system
DocumentEarly automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.07
Location: Arquivo PCA - Pasta 2/2010
Title:
Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response
Publication year: 2011
URL:
http://www.cogneurosociety.org/wordpress/wp-content/themes/CNStheme/downloads/CNS2011_Program.pdf
Abstract/Results: ABSTRACT:
The violation of a regular sound pattern by irregular or novel stimuli is reflected in the mismatch negativity, a component of the human auditory evoked potential (AEP), with a latency of 100-250 ms and main sources in the auditory cortices. Evidence for auditory novelty detection however has also been reported at much shorter latencies (15 ?– 30 ms after stimulus onset) as revealed by single- and multiunit recordings in the auditory cortex and midbrain of animals. In this study, we aimed at finding traces of fast auditory novelty detection in the human AEP during a passive intensity oddball paradigm. An oddball condition using click stimuli (standard stimulus = 50 dB SL; deviant stimulus [14%] = 40 dB SL), a reversed oddball condition (standard stimulus = 40 dB SL; deviant stimulus [14%] = 50 dB SL) and a control condition (random presentation of 7 stimuli with different intensities ranging from 10-70 dB SL, 14 % probability each) were applied. The EEG was recorded from 7 scalp electrodes and the data was analyzed in the ranges of the auditory brainstem response, the middle-latency response, and the long-latency response. In the middle-latency range, deviants elicited a significantly more negative response than standards of the same intensity
at the descending slope of the Na component (21-27 ms after stimulus onset). This outcome suggests that the human auditory novelty detection system comprises fast processes which are taking place at latencies similar to those found in single- and multiunit recordings in animals.
Accessibility: Document does not exist in file
Language:
eng
Author:
Althen, H.
Secondary author(s):
Grimm, S., Slabu, L., Escera, C.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Althen, H., Grimm, S., Slabu, L., & Escera, C. (2011). Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response. In Abstract book of the Cognitive Neuroscience Society - 2011 Annual Meeting (pp. 35-36). San Francisco, CA.
Indexed document: No
Keywords: Mismatch negativity (MMN) / Auditory evoked potentials (AEPs) / Auditory novelty detection

Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response

Early automatic detection of intensity deviants reflected in the middle-latency range of the human electrical brain response
DocumentRapid detection of changes in sound source location as revealed by human auditory evoked potentials2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-037
Location: Arquivo PCA - Pasta 2/2010
Title:
037 - Psychophysiological mechanisms of hierarchical novelty detection in the human auditory brain
Duration: 2011-04 - 2013-03
Researcher(s):
Carles Escera, Sabine Grimm, Marc Recasens
Institution(s): Research Institute for Brain, Cognition and Behavior (IR3C) and Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
3 Articles
Language: eng
Author:
Escera, C.
Secondary author(s):
Grimm, S., Recasens, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Audition / Brain structure and function

Reference code: PT/FB/BL-2010-037.08
Location: Arquivo PCA - Pasta 2/2010
Title:
Rapid detection of changes in sound source location as revealed by human auditory evoked potentials
Publication year: 2011
URL:
http://www.cogneurosociety.org/wordpress/wp-content/themes/CNStheme/downloads/CNS2011_Program.pdf
Abstract/Results: ABSTRACT:
The rapid discrimination of sound source locations is crucial in order to group the auditory input and to selectively attend to specific sound sources. The detection of changes in sound location has been related to the mismatch negativity (MMN), an auditory evoked potential (AEP) occurring at 100-250 ms after change onset. However, animal recordings suggest much faster neural responses to contextually new or deviant stimuli and recent studies have observed early indices of human auditory deviance detection for spectral changes in the middle-latency response (MLR) of the AEP. The present study investigates the processing of sound location changes by measuring the MLR during an oddball paradigm in 20 human subjects. The auditory sequences were comprised of clicks presented via loudspeakers in oddball blocks (80 % standards: 30^(0); 20 % deviants: 60^(0)), reversed oddball blocks (standards: 60^(0); deviants: 30^(0)), and control blocks (randomly from -60^(0), - 30^(0), 0^(0), 30^(0), 60^(0)). Oddball blocks were presented both in the left and right hemifield. Clicks presented at deviant locations elicited a larger Na component of the MLR peaking at 17-23 ms compared to clicks presented at the same site when it served as the standard or control location. Whereas the Na component itself was not lateralized, the deviancerelated increase in Na amplitude showed a significant dominance over the hemisphere contralateral to the side of stimulation. This indicates that the discrimination of rare spatial changes initiates very quickly, at about 20 ms after sound onset, reflected by an enhanced activity dominantly in contralateral auditory cortex regions.
Accessibility: Document does not exist in file
Language:
eng
Author:
Grimm, S.
Secondary author(s):
Althen, H., Recasens, M., Escera, C.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Grimm, S., Althen, H., Recasens, M., & Escera, C. (2011). Rapid detection of changes in sound source location as revealed by human auditory evoked potentials. In Abstract book of the Cognitive Neuroscience Society - 2011 Annual Meeting (p. 21). San Francisco, CA.
Indexed document: No
Keywords: Mismatch negativity (MMN) / Auditory evoked potentials (AEPs) / Deviant sounds

Rapid detection of changes in sound source location as revealed by human auditory evoked potentials

Rapid detection of changes in sound source location as revealed by human auditory evoked potentials