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BIAL Foundation
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DocumentFinal report - The effect of conscious states of neural activity2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-037
Location: Arquivo PCA - Pasta 12/2004
Title:
037 - The effect of conscious states of neural activity
Duration: 2005-02 - 2007-07
Researcher(s):
Shimon Ullman, Elisha Moses, Shimshon Jacobi
Institution(s): The Weizmann Institute of Science, Rehovot (Israel)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report (3 copies)
Final report (2 copies)
Language: eng
Author:
Ullman, S.
Secondary author(s):
Moses, E., Jacobi, S.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes / Consciousness / Assessment tools

Reference code: PT/FB/BL-2004-037.01
Location: Arquivo PCA - Pasta 12/2004
Title:
Final report - The effect of conscious states of neural activity
Publication year: 2007
URL:
http://www.bial.com/fotos/gca/1188986463bolsa3704.pdf
Abstract/Results: RESULTS:
The research project searched for empirical evidence related to the interactions of conscious perception and neural activity. The study developed and used two experimental approaches. The first was based on the use of a patterned neuronal culture, and the second on an EEG measured during a two-person interaction in a computer game. In both approaches the experiment tested the possible effect of conscious state of the person playing the computer game on the level of neuronal activity. The experiments were designed such that an effect of this type would be detected by a difference in the measured neural activity during game playing time compared with a reference pause period.
In the neuronal culture setup, the number of experiments was limited by the number of neurally responsive cultures. In one culture, activity during game periods was significantly higher that during reference period. In a second active culture, the activity was lower during game playing compared to the reference period, but the difference was relatively small. In the EEG setup, considerable efforts were devoted to the development of a stable measurement protocol and algorithms to automatically select the most appropriate electrode signals. The results of the two-person setup have not shown so far conclusive consciousness effects, but the amount of data collected so far is too limited to draw final conclusions. It will be possible to use the approach we developed to efficiently collect additional data and analyze the problem in greater detail. The results also show that the application of learning algorithms to automatically identify and use the most appropriate signals will be highly beneficial in future studies.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Ullman, S.
Secondary author(s):
Moses, E.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Consciousness / Neural activity

Final report - The effect of conscious states of neural activity

Final report - The effect of conscious states of neural activity
DocumentFinal report - Neural mechanisms of social transmission of fear2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-178
Location: Arquivo PCA - Pasta 18/2010
Title:
178 - Neural mechanisms of social transmission of fear
Duration: 2011-10 - 2013-07
Researcher(s):
Marta de Aragão Pacheco Moita, Ana Pereira, Susana Quelhas Lima
Institution(s): Champalimaud Foundation, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
1 Article
Language: eng
Author:
Moita, M.
Secondary author(s):
Pereira, A. G., Lima, S.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Affective and social behavior / Animal behavior / Cognitive processes / Learning

Reference code: PT/FB/BL-2010-178.01
Location: Arquivo PCA - Pasta 18/2010
Title:
Final report - Neural mechanisms of social transmission of fear
Publication year: 2013
URL:
http://www.bial.com/imagem/Bolsa17810_04022014.pdf
Abstract/Results: RESULTS:
In addition to learning signs associated with specific threats, animals can use con-specific alarm signals (such as alarm pheromones and calls) and eavesdrop on other species. These mechanisms allow animals to avoid the necessity of learning through what might be a fatal encounter with a predator. Our laboratory has recently shown that rats use freezing as a signal of threat. In our study, we trained one rat, the demonstrator, to fear a tone cue and the next day tested their fear of the cue in the presence of the cage-mate, the observer. We found that observer rats perceive the cessation of movement-evoked sound (caused by freezing of the demonstrator) as a signal of danger and its resumption as a signal of safety. In addition, we have found that observer rats previously exposed to footshocks display observational freezing, but naive observer rats do not, indicating that learning from self-experience with an aversive event is important for rats to respond to freezing displayed by others. We hypothesize that rats learn to associate their own freezing response with the aversive shock, such that later on freezing itself becomes an alarm cue. Indeed, experiments in the lab have shown that exposure to shock, or contextual fear learning in the absence of freezing, are not sufficient to allow for observational freezing. This set of experiments paved the way to the underpinnings of the neural mechanism underlying social transmission of fear in rats.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Moita, M.
Secondary author(s):
Pereira, A. G., Lima, S.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Social transmission of fear / Neural activity

Final report - Neural mechanisms of social transmission of fear

Final report - Neural mechanisms of social transmission of fear
DocumentNeural substrates of withholding impulsive actions in rat frontal cortex2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-127
Location: Arquivo PCA - Pasta 6/2008
Title:
127 - Prefrontal control of impulsive action
Duration: 2009-02 - 2011-03
Researcher(s):
Masayoshi Murakami, Zachary F. Mainen
Institution(s): Instituto Gulbenkian de Ciência, Oeiras (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Final report
Poster
Language: eng
Author:
Murakami, M.
Secondary author(s):
Mainen, Z.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes

Reference code: PT/FB/BL-2008-127.04
Location: Arquivo PCA - Pasta 6/2008
Title:
Neural substrates of withholding impulsive actions in rat frontal cortex
Publication year: 2010
URL:
http://fens2010.neurosciences.asso.fr/abstracts/R6/A176_42.html
Abstract/Results: ABSTRACT:
Withholding impulsive actions for short term gains to achieve longer term goals is an important facet of goal-directed behavior. The frontal cortex has been hypothesized to exert top-down inhibition of impulsive actions, but little is known about the nature of the neural signals responsible for such control. To address this question, we have developed a novel impulse control task in rats and begun to investigate the neural signals of frontal cortical areas, namely medial frontal cortex (MFC) and secondary motor cortex (M2), during the task.
In the impulse control task, subjects interact with a waiting port and a reward port. While waiting, two tones are generated, the first at a fixed short delay (0.4 s) and the second at a longer random delay (exponentially-distributed, min. 0.7 s, approx. 2s mean). Responses after the first tone garner a reward, but the amount is 3-4 times larger after the second tone. For a given set of reward amounts and delays, the time a rat is willing to wait varies randomly from trial to trial, approximating the distribution of second tone delays.
To characterize neural signals related to impulse control, we made single-unit recordings from MFC and M2 neurons, testing for signals that correlated on a trial-by-trial basis with waiting time. While approximately 20% of neurons in M2 (109/548 neurons) showed activity that correlated with and predicted waiting time, only 6.6% of MFC neurons (8/122 neurons) showed such a predictive activity. Waiting-predictive neurons in M2 showed a variety of time courses of activity. The most frequent one was a phasic signal locked to waiting-port entry, but other neurons showed ramping activity peaking at waiting-port exit.
To test whether the predictive activity in M2 is specific to waiting action or not, we compared the activity during two impulse control tasks which require different actions for waiting, nose-poke for one task and lever-press for the other. Most of the predictive signals are specific to one type of waiting, which suggests the action specificity of the predictive signal.
These results establish a task suitable for studying impulse control, reveal properties of single neuronal activity in frontal cortex during the task and suggest a role of M2 in planning timing of actions.
Accessibility: Document does not exist in file
Language:
eng
Author:
Murakami, M.
Secondary author(s):
Vicente, M., Costa, G., Mainen, Z.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Murakami, M., Vicente, M., Costa, G., & Mainen, Z. (2010). Neural substrates of withholding impulsive actions in rat frontal cortex. FENS Abstr., vol.5, 176.42
Indexed document: No
Keywords: Impulse control / Frontal cortex / Rat / Neural activity