History
Processing, please wait...
Database
search
in
Filter year from
to
Language
Country
  • Enter your search phrase in the search box.
  • General search:
    • The Boolean operator AND between the terms is assumed by default. If you enter the words European Union in the search box, the system returns all records in which both words occur, regardless of their order.
    • When entering a set of words in quotes, e.g "european union", all records containing the literal term "European Union" will be retrieved.
  • Search by access fields (e.g. author, title, etc.):
    • To direct your search, choose the field in which you want to search the word or expression.
    • Search in the field assumes by default the expression in quotes, e.g. European union will retrieve all records containing the literal term "European Union"
  • To perform more complex searches, additional words or expressions may be added.
  • If you want to refine the search results, you can always access the link "search" in the upper left corner of the page of search results.
  • The search engine is not case sensitive. For example, the word congress has the same meaning that Congress or CONGRESS.
  • To truncate your search expression, use the $ character
  • You can filter the results of your search by a date or date range, filling the appropriate boxes.
Base:
BIAL Foundation
Search:
DE:"Neuroendocrinology"
Results
1
to
4
from
4
found.
View
Selection Description
Type Title Begin End
DocumentFinal report - The Neuropsychophysiological Basis of Empathy: The role of neuroendocrine; autonomic and central nervous system variables2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-089
Location: Arquivo PCA - Pasta 11/2008
Title:
089 - The Neuropsychophysiological Basis of Empathy: The role of neuroendocrine, autonomic and central nervous system variables
Duration: 2009-01 - 2012-03
Researcher(s):
Óscar Filipe Coelho Neves Gonçalves, Patrícia Silva, Ana Pinheiro
Institution(s): Cipsi – Centro de Investigação em Psicologia, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Articles
Language: eng, por
Author:
Gonçalves, O.
Secondary author(s):
Silva, P., Pinheiro, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Empathy / Assessment tools / Psychoneuroimmunology / Endocrinology / Brain structure and function

Reference code: PT/FB/BL-2008-089.01
Location: Arquivo PCA - Pasta 11/2008
Title:
Final report - The Neuropsychophysiological Basis of Empathy: The role of neuroendocrine; autonomic and central nervous system variables
Publication year: 2012
URL:
https://www.bial.com/imagem/Bolsa8908_24042015.pdf
Abstract/Results: ABSTRACT:
The defined objectives for this project were: (i) to develop and validate a scale of empathy to assess empathy skills, (ii) assess the psychophysiological, neuroendocrine and neuroimagiological correlates related to different empathic responses, and (iii) evaluate different category of stimuli and psychophysiological measures related to emotional modulation. Initially, a large dataset of empathy-eliciting vignettes were developed and validated in order to allow the assessment of the empathy responding ability. This database for research and clinical application is based on three level of empathic response, ranging from less to more empathic. At the peripheral level, we showed that the highest level of empathic response were accompanied by changes in the heart rate, suggesting that the cardiac response is a good candidate for a biomarker of complex human process, such as the empathic response. At the neuroimagiological level, we found that more empathic responses were associated with sustained activation of the default mode network, which has been associated with emotional and cognitive domains of empathy. Additionally, our results also suggest that the medial prefrontal cortex seems to execute a reciprocal modulation of cognitive and emotional regulating functions during an empathic experience. In order to address others of our objectives, results showed that the cognitive component of the event-related potential could not function as a psychophysiological measure of emotional modulation, while the skin conductance and cardiac measures reflect similar processes of sustained attention, representing a good predictor of the attentional resources allocated to demanding tasks.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng / por
Author:
Gonçalves, O.
Secondary author(s):
Silva, P., Pinheiro, A.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Empathy / Neuropsychophysiology / Neuroimaging / Endocrinology / Neuroendocrinology / Empathy scale
DocumentFinal report - Quality of Subjective Experience and Psychophysiology: Implications for Optimal Human Functioning2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-130
Location: Arquivo PCA - Pasta 12/2008
Title:
130 - As Experiências Óptimas na vida diária e Padrões Fisiológicos associados: para um conhecimento da Personalidade Autotélica
Duration: 2009-01 - 2011-09
Researcher(s):
Teresa Freire, Mário João Pereira Sequeira Santos, Marta Bassi, Gabriela Matias
Institution(s): Centro de Investigação em Psicologia (CIPsi), Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Articles
Posters
Language: por, eng
Author:
Freire, T.
Secondary author(s):
Santos, M. J., Bassi, M., Matias, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Personality / Psychoneuroimmunology / Endocrinology

Reference code: PT/FB/BL-2008-130.01
Location: Arquivo PCA - Pasta 12/2008
Title:
Final report - Quality of Subjective Experience and Psychophysiology: Implications for Optimal Human Functioning
Publication year: 2012
URL:
http://www.bial.com/imagem/Bolsa13008_04022014.pdf
Abstract/Results: RESULTS:
Objectives: The autotelic personality is associated with traits associated with positive mental and physical health outcomes. Furthermore, the autotelic personality was associated with a better functioning in daily life contexts. The aim of this study was to investigate whether autotelic personality characteristics are associated with experiential and physiological momentary responses to daily life contexts.
Methods: Sixty-seven female college students from the University of Minho, Portugal, used the Experience Sampling Method during a week, completing questionnaires and collecting saliva samples 8 times daily. We performed multi-level analyses to investigate the effects of autotelic personality characteristics on subjective experience and cortisol secretion.
Results: Autotelic students experienced lower negative affect and fatigue, and higher levels of engagement in daily life, than less autotelic students. In solitude, autotelic students did not experience heightened negative affect in solitude as their less autotelic individuals did. Although daily solitude was associated with heightened cortisol levels, we did not find a moderating effect of autotelic personality on cortisol levels in solitude.
Conclusions: Current results shed new clues about the assessment of the psychophysiology of the autotelic personality. Findings help clarify how daily contexts influence the affective and neuroendocrine responses of individuals, contributing for future health outcomes.
Discussion: We discuss future directions such as the inclusion of other physiological measures (e.g., salivary alpha-amylase) and the study of different moments in time to understand the effects of positive personality characteristics on processes such as adaptation and health outcomes.
Accessibility: Document does not exist in file
Language:
eng
Notes:
The final report is presented as a doctoral thesis
Author: Matias, G.
Document type:
Doctoral thesis. Final report
Number of reproductions:
1
Reference:
Matias, G. (2012). Quality of Subjective Experience and Psychophysiology: Implications for Optimal Human Functioning. (Unpublished doctoral dissertation, Universidade do Minho, Portugal).
Indexed document: No
Keywords: Psychophysiology / Neuroendocrinology / Flow model / Autotelic personality / Affectivity / Cortisol / Optimal human functioning

Novo ficheiro

Novo ficheiro

Novo ficheiro

Novo ficheiro
DocumentEffects of institutionalization on infants’ physical growth, mental development, temperament, neuro-endocrine, and social-emotional functioning: Preliminary data2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-013
Location: Arquivo PCA - Pasta 15/2006
Title:
013 - Vinculação em bebés institucionalizados e competência narrativa dos seus principais cuidadores: Estudo sobre a actividade cardíaca do bebé na interacção com a figura de cuidados através do BioBeAMS 2.0
Duration: 2007-04 - 2010-05
Researcher(s):
Isabel Soares, João Paulo Silva Cunha, Margarida Isabel Rangel Santos Henriques, Carla Cristina Esteves Martins, Pedro Miguel Brito da Silva Dias
Institution(s): Centro de Investigação em Psicologia (CIPSi), Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Conference papers (posters and oral communications)
Language: por
Author:
Soares, I.
Secondary author(s):
Cunha, J., Henriques, M. R., Martins, C., Dias, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Affective and social behavior / Attachment / Developmental psychology

Reference code: PT/FB/BL-2006-013.06
Location: Arquivo PCA - Pasta 15/2006
Title:
Effects of institutionalization on infants’ physical growth, mental development, temperament, neuro-endocrine, and social-emotional functioning: Preliminary data
Publication year: 2009
URL:
http://www.psychotherapyresearch.org/associations/6344/files/events/santiago/boa_santiago.pdf
Abstract/Results: ABSTRACT:
Clinicians and researchers have been documenting the deleterious effects of institutional rearing on multiple developmental domains of young children. Most of these studies were conducted in very deprived institutional settings. In Portugal there is a lack of empirical evidence about the developmental effects in children reared in institutions. The sample is composed by fifty children early deprived from parental care and placed in institutions from birth to 30 months. Two groups of children were assessed: children newly admitted at the institution (Group 1) and children that had been at the institution for at least 6 months (Group 2). The measures were: a) standard measures of weight, height, head circumference for physical growth; b) the Bayley Scales of Infant Development III for assessment of cognitive development; c) saliva samples for determination the cortisol levels; d) Ages & Stages Questionnnaires – SE for social-emotional development (Squires,Bricker & Twombly, 2002), and the Infant Characteristics Questionnaire (Bates, Freeland & Lounsbury,1979) to assess temperament. Physical growth and neuro-cognitive functioning differences will be examined between groups. In addition, intra-group variability in neuro-cognitive functioning and social emotional development will be explored within Group 2 as a function of the length of institutional rearing.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Soares, I.
Secondary author(s):
Silva, J., Marques, S., Baptista, J., Pereira, M., Mesquita, A. R., Teixeira, D., Sousa, N., Henriques, M. R., Palha, J., Dias, P., Martins, C.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Soares, I., Silva, J., Marques, S., Baptista, J., Pereira, M., ... Martins, C. (2009). Effects of institutionalization on infants’ physical growth, mental development, temperament, neuro-endocrine, and social-emotional functioning: Preliminary data. In Abstract book of the 40th International Annual Meeting of the Society for Psychotherapy Research, Santiago do Chile (pp. 186-187). Society for Psychotherapy Research.
Indexed document: No
Keywords: Institutionally reared children / Infant / Development / Temperament / Neuroendocrinology

Abstract

Abstract

Poster

Poster
DocumentHypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-036
Location: Arquivo PCA - Pasta 18/2006
Title:
036 - The psychophysiology of neurological abnormalities in first episode psychosis and in healthy individuals - A study using multimodal brain imaging
Duration: 2007-03 - 2010-09
Researcher(s):
Paola Dazzan, Philip McGuire, Carmine Pariante, Marta Di Forti, Julia Lappin, Valeria Mondelli
Institution(s): Division of Psychological Medicine, Institute of Psychiatry, London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
1 Article
Language: eng
Author:
Dazzan, P.
Secondary author(s):
McGuire, P., Pariante, C., Di Forti, M., Lappin, J., Mondelli, V.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders / Body structure and function / Audition / Movement / Vision

Reference code: PT/FB/BL-2006-036.07
Location: Arquivo PCA - Pasta 18/2006
Title:
Hypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis
Publication year: 2011
URL:
http://www.psyneuen-journal.com/article/PIIS030645301100268X/abstract?rss=yes
Abstract/Results: ABSTRACT:
BACKGROUND:
Abnormalities in hypothalamic-pituitary-adrenal (HPA) axis activity have been reported in patients with psychosis, but it is still unclear how these are related to the clinical symptomatology. Inconsistent findings have emerged from previous studies on the association between cortisol levels and clinical symptoms. Methodological and/or clinical factors, such as patients' diagnosis or illness phase, might partially account for these inconsistencies. The aim of this study was to investigate the association between HPA axis activity and clinical symptoms in first-episode psychosis, taking into account diagnosis and illness phase.
METHOD:
Saliva samples were collected in 55 subjects with first-episode psychosis to assess the Cortisol Awakening Response (CAR) and diurnal cortisol levels (AUC-DAY). Severity of symptoms was assessed with the Positive and Negative Syndrome Scale (PANSS). Scores for subscales and symptom dimensions were used as predictors in multivariate analyses in different diagnostic subgroups and in clinically remitted patients. In addition, a systematic review of the literature on this topic was conducted.
RESULTS:
In subjects with schizophrenia (n=36), the CAR was predicted by the severity of positive symptoms (beta=0.47, p=0.04); in subjects with depressive psychoses (n=8) the CAR was predicted by excitement (beta=0.58, p=0.005), disorganization (beta=0.39, p=0.007) and depressive symptoms (beta=0.32, p=0.005). In patients with bipolar psychoses (n=11) AUC-DAY was predicted negatively by disorganization (beta=-2.82, p=0.009) and positively by excitement (beta=2.06, p=0.009) and positive symptoms (beta=1.28, p=0.02). In the sample in clinical remission (n=9), the CAR was associated with the severity of positive symptoms (beta=1.34, p=0.009) and, negatively, with excitement (beta=-1.05, p=0.04). The systematic review (on a total of 28 papers, including n=1022 patients), found that in patients with psychosis cortisol levels have been associated with the severity of multiple symptom dimensions.
CONCLUSIONS:
HPA axis activity is associated with the severity of multiple types of symptoms in first-episode psychosis. Patients' diagnosis and clinical phase partially influence these associations.
Accessibility: Document does not exist in file
Language:
eng
Author:
Belvederi Murri, M.
Secondary author(s):
Pariante, C., Dazzan, P., Hepgul, N., Papadopoulos, A., Zunszain, P., Di Forti, M., Murray, R., Mondelli, V.
Document type:
Article
Number of reproductions:
1
Reference:
Belvederi Murri, M., Pariante, C., Dazzan, P., Hepgul, N., Papadopoulos, A., Zunszain, P., Di Forti, M., Murray, R., & Mondelli, V. (2011). Hypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis. Psychoneuroendocrinology, 37(5), 629-644. https://doi.org/10.1016/j.psyneuen.2011.08.013
2-year Impact Factor: 5.809|2011
Times cited: 70|2025-09-10
Indexed document: Yes
Quartile: Q1
Keywords: Cortisol / Cortisol awakening response / Hypothalamic-pituitary-adrenal axis / Symptoms / Psychosis / Schizophrenia / Bipolar / Depression / Diagnosis / Remission / Neuroendocrinology