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DocumentFluctuations in neuronal synchronization in brain activity correlate with the subjective experience of visual recognition2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-033
Location: Arquivo PCA - Pasta 15/2004
Title:
033 - Dynamic brain patterns in neocortical areas during interpersonal transactions
Duration: 2005-01 - 2008-07
Researcher(s):
Richard Wennberg, Jose Luis Perez Velazquez
Institution(s): Krembil Neuroscience Centre, Toronto Western Hospital and The Hospital for Sick Children, University of Toronto (Canada)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Wennberg, R.
Secondary author(s):
Perez Velazquez, J. L.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Pain / Emotion / Empathy

Reference code: PT/FB/BL-2004-033.07
Location: Arquivo PCA - Pasta 15/2004
Title:
Fluctuations in neuronal synchronization in brain activity correlate with the subjective experience of visual recognition
Publication year: 2007
URL:
http://link.springer.com/article/10.1007%2Fs10867-007-9041-4
Abstract/Results: ABSTRACT:
The scientific study of subjective experience is a current major research area in the neurosciences. Coordination patterns of brain activity are being studied to address the question of how brain function relates to behaviour, and particularly methods to estimate neuronal synchronization can unravel the spatio-temporal dynamics of the transient formation of neuronal assemblies. We report here a biophysical correlate of subjective experience. Subjects visualised figures with different levels of noise, while their brain activity was recorded using magnetoencephalography (MEG), and reported the moment in time (corresponding to a noise level) of figure recognition, which varied between individuals, as well as the moment when they saw the figure more clearly, which was mostly common among the participants (thus less subjective). This latter moment is considered to represent psychophysical stochastic resonance (PSR). Fluctuations in neuronal synchronization, quantified using a diffusion coefficient, were lower in occipital cortex when subjects recognised the figure, for a certain noise level, but did not correlate with the moment of PSR. A different pattern was observed in frontal cortex, where lower values of the diffusion coefficient in neuronal synchronization was maintained from the moment of recognition to the moment of PSR. No specific pattern was found analysing signals from temporal or parietal cortical areas. These observations provide support for distinct synchronization patterns in different cortical areas, and represent another demonstration that the subjective, first-person perspective is accessible to scientific methods.
Accessibility: Document does not exist in file
Language:
eng
Author:
Perez Velazquez, J. L.
Secondary author(s):
Garcia Dominguez, L., Guevara Erra, R.
Document type:
Article
Number of reproductions:
1
Reference:
Perez Velazquez, J. L., Garcia Dominguez, L., & Guevara Erra, R. (2007). Fluctuations in neuronal synchronization in brain activity correlate with the subjective experience of visual recognition. Journal of Biological Physics, 33(1), 49-59. https://doi.org/10.1007/s10867-007-9041-4
2-year Impact Factor: 0.695|2007
Times cited: 4|2025-09-09
Indexed document: Yes
Quartile: Q4
Keywords: Visual perception / Diffusion / Fluctuations / Synchronization / Noise / Brain / Magnetoencephalography / 87.19.La / 05.45.Xt
DocumentDoes impedance matter when recording spikes with polytrodes?2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-190
Location: Arquivo PCA - Pasta 16/2012
Title:
190 - Interfacing Technology with the Brain: Novel materials for implantable neural devices
Duration: 2013-06 - 2016-09
Researcher(s):
Adam Kampff, Elvira Fortunato, Pedro Barquinha, Joana Neto, Joana Nogueira
Institution(s): Fundação Champalimaud and CENIMAT - Materials Research Center, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
Language: eng
Author:
Kampff, A.
Secondary author(s):
Fortunato, E., Barquinha, P., Neto, J., Nogueira, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Assessment tools

Reference code: PT/FB/BL-2012-190.04
Location: Arquivo PCA - Pasta 16/2012
Title:
Does impedance matter when recording spikes with polytrodes?
Publication year: 2018
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188074/
Abstract/Results: ABSTRACT:
Extracellular microelectrodes have been widely used to measure brain activity, yet there are still basic questions about the requirements for a good extracellular microelectrode. One common source of confusion is how much an electrode's impedance affects the amplitude of extracellular spikes and background noise. Here we quantify the effect of an electrode's impedance on data quality in extracellular recordings, which is crucial for both the detection of spikes and their assignment to the correct neurons. This study employs commercial polytrodes containing 32 electrodes (177 mu m(2)) arranged in a dense array. This allowed us to directly compare, side-by-side, the same extracellular signals measured by modified low impedance (similar to 100 k Omega) microelectrodes with unmodified high impedance (similar to 1 M Omega) microelectrodes. We begin with an evaluation of existing protocols to lower the impedance of the electrodes. The poly (3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT-PSS) electrodeposition protocol is a simple, stable, and reliable method for decreasing the impedance of a microelectrode up to 10-fold. We next record in vivo using polytrodes that are modified in a 'chess board' pattern, such that the signal of one neuron is detected by multiple coated and non-coated electrodes. The performance of the coated and non-coated electrodes is then compared on measures of background noise and amplitude of the detected action potentials. If the proper recording system is used, then the impedance of a microelectrode within the range of standard polytrodes (similar to 0.1 to 2 M Omega) does not greatly affect data quality and spike sorting. This study should encourage neuroscientists to stop worrying about one more unknown.
Accessibility: Document exists in file
Language:
eng
Author:
Neto, J. P.
Secondary author(s):
Baião, P., Lopes, G., Frazão, J., Nogueira, J., Fortunato, E., Barquinha, P., Kampff, A. R.
Document type:
Article
Number of reproductions:
1
Reference:
Neto, J. P., Baião, P., Lopes, G., Frazão, J., Nogueira, J., Fortunato, E., Barquinha, P., & Kampff, A. R. (2018). Does impedance matter when recording spikes with polytrodes?. Frontiers in neuroscience, 12: 715. https://doi.org/10.3389/fnins.2018.00715
2-year Impact Factor: 3.648|2018
Times cited: 75|2025-09-17
Indexed document: Yes
Quartile: Q2
Keywords: Microelectrodes / Impedance / Spikes / Noise / Coating

Does impedance matter when recording spikes with polytrodes?

Does impedance matter when recording spikes with polytrodes?