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DocumentExcess of high frequency electroencephalogram oscillations in boys with autism2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-087
Location: Arquivo PCA - Pasta 9/2004
Title:
087 - Early neurophysiological correlates of autism: visual attention and EEG rhythms
Duration: 2005-01 - 2007-04
Researcher(s):
Stroganova Tatiana Alexandrovna, Elam Mikael, Orekhova Elena, Tsetlin Mariana Mihailovna, Morozov Alexei Alexandrovich
Institution(s): Moscow University for Psychology and Education, Faculty of Abnormal Psychology, Moscow (Russia)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
2 Articles
3 Unpublished document (1 poster and 2 articles submitted for publication)
Language: eng
Author:
Stroganova, T. A.
Secondary author(s):
Elam, M., Orekhova, E. V., Tsetlin, M. M., Morozov, A. A.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Childhood and adolescent disorders / Autism spectrum disorder (ASD)

Reference code: PT/FB/BL-2004-087.03
Location: Arquivo PCA - Pasta 9/2004
Title:
Excess of high frequency electroencephalogram oscillations in boys with autism
Publication year: 2007
URL:
http://www.sciencedirect.com/science/article/pii/S0006322307000145
Abstract/Results: ABSTRACT:
BACKGROUND:
An elevated excitation/inhibition ratio has been suggested as one mechanism underpinning autism. An imbalance between cortical excitation and inhibition may manifest itself in electroencephalogram (EEG) abnormalities in the high frequency range. The aim of this study was to investigate whether beta and gamma range EEG abnormalities are characteristic for young boys with autism (BWA).
METOHDS:
EEG was recorded during sustained visual attention in two independent samples of BWA from Moscow and Gothenburg, aged 3 to 8 years, and in age matched typically developing boys (TDB). High frequency EEG spectral power was analyzed.
RESULTS:
In both samples, BWA demonstrated a pathological increase of gamma (24.4–44.0 Hz) activity at the electrode locations distant from the sources of myogenic artefacts. In both samples, the amount of gamma activity correlated positively with degree of developmental delay in BWA.
CONCLUSIONS:
The excess of high frequency oscillations may reflect imbalance in the excitation–inhibition homeostasis in the cortex. Given the important role of high frequency EEG rhythms for perceptual and cognitive processes, early and probably genetically determined abnormalities in the neuronal mechanisms generating high frequency EEG rhythms may contribute to development of the disorder. Further studies are needed to investigate the specificity of the findings for autism.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Orekhova, E. V.
Secondary author(s):
Stroganova, T. A., Nygren, G., Tsetlin, M. M., Posikera, I. N., Gillberg, C., Elam, M.
Document type:
Article
Number of reproductions:
1
Reference:
Orekhova, E. V., Stroganova, T. A., Nygren, G., Tsetlin, M. M., Posikera, I. N., Gillberg, C., & Elam, M. (2007). Excess of high frequency electroencephalogram oscillations in boys with autism. Biological Psychiatry, 62(9), 1022–1029. https://doi.org/10.1016/j.biopsych.2006.12.029
2-year Impact Factor: 8.456|2007
Times cited: 213|2024-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Autism spectrum disorder (ASD) / Beta / Children / Electroencephalogram (EEG) / Gamma / High frequency / Oscillations

Excess of high frequency electroencephalogram oscillations in boys with autism

Excess of high frequency electroencephalogram oscillations in boys with autism
DocumentTwenty-four hours retention of visuospatial memory correlates with the number of parietal sleep spindles2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-168
Location: Arquivo PCA - Pasta 13/2004
Title:
168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Duration: 2005-02 - 2007-07
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Dániel Fabó
Institution(s): National Institute of Psychiatry and Neurology, Department of Neurology, Epilepsy Center, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Epilepsy / Sleep and dreams

Reference code: PT/FB/BL-2004-168.03
Location: Arquivo PCA - Pasta 13/2004
Title:
Twenty-four hours retention of visuospatial memory correlates with the number of parietal sleep spindles
Publication year: 2006
URL:
http://www.ncbi.nlm.nih.gov/pubmed/16714084
Abstract/Results: ABSTRACT:
Recent evidence suggests that the sleep-dependent consolidation of declarative memories relies on the non-rapid eye movement (NREM) rather than the rapid eye movement (REM) phase of sleep. Moreover, a few studies both at the cellular and the behavioural levels have suggested the involvement of sleep spindles, the most synchronous oscillatory waveforms during NREM sleep stage 2, in this process. Our previous study showed that overnight verbal memory retention correlates with the total number of sleep spindles in left frontocentral areas, while spindling in other regions did not correlate with mnemonic retention. In the present study, we show that retention of visuospatial memories over a 24-h period correlates with the total number of sleep spindles detected over parietal regions during the intervening night-time sleep. This result provides further evidence for the association between sleep spindle activity and declarative memory consolidation, and suggests that visuospatial and verbal memory retention differ in the topographic distribution of the NREM spindle activity with which they are associated.
Accessibility: Document does not exist in file
Language:
eng
Author:
Clemens, Z.
Secondary author(s):
Fabó, D., Halász, P.
Document type:
Article
Number of reproductions:
1
Reference:
Clemens, Z., Fabó, D., & Halász, P. (2006). Twenty-four hours retention of visuospatial memory correlates with the number of parietal sleep spindles. Neuroscience Letters, 403(1-2), 52-56. https://doi.org/10.1016/j.neulet.2006.04.035
2-year Impact Factor: 2.092|2006
Times cited: 115|2024-02-05
Indexed document: Yes
Quartile: Q3
Keywords: Sleep spindles / Rey-Osterrieth complex figure task / Memory consolidation / Oscillations / Hippocampus / Declarative memory

Twenty-four hours retention of visuospatial memory correlates with the number of parietal sleep spindles

Twenty-four hours retention of visuospatial memory correlates with the number of parietal sleep spindles
DocumentSwitching-on and -off of bistable spontaneous discharges in rat spinal deep dorsal horn neurons2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-084
Location: Arquivo PCA - Pastas 19 a 20/2004
Title:
084 - A consciência da dor: Alterações induzidas por dor crónica nos mecanismos neurobiológicos de aprendizagem, atenção e recompensa
Duration: 2005-01 - 2008-11
Researcher(s):
Vasco Miguel Clara Lopes Galhardo, Deolinda Maria Valente Alves de Lima Teixeira, Miguel Santos Pais-Vieira, Clara Maria Pires Costa Bastos Monteiro
Institution(s): IBMC - Instituto de Biologia Molecular e Celular, Porto (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng / por
Related objects:
PT/FB/BL-2008-126
Author: Galhardo, V.
Secondary author(s):
Lima, D., Pais-Vieira, M., Monteiro, C.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain / Cognitive processes / Decision-making / Memory / Attention / Learning / Brain structure and function / Assessment tools

Reference code: PT/FB/BL-2004-084.08
Location: Arquivo PCA - Pasta 19/2004
Title:
Switching-on and -off of bistable spontaneous discharges in rat spinal deep dorsal horn neurons
Publication year: 2006
URL:
http://www.sciencedirect.com/science/article/pii/S0304394006000231
Abstract/Results: ABSTRACT:
Somatosensory deep dorsal horn spinal neurons were previously shown to present in vitro a bistable state of activity in which a fixed firing rate is maintained over prolonged periods in the absence of stimulation. Those periods of enhanced spinal spontaneous discharge may play a role in the genesis or maintenance of hyperalgesic states, where episodes of durable spontaneous pain are commonly reported. Here we show in vivo that a small percentage of deep spinal neurons (4% of the recorded population) are capable of rapidly shifting between low-frequency and high-frequency levels of spontaneous activity. At least one of the transitions between the two states was induced by stimulation of the receptive field, making this an interesting and unique case in which stable firing rates are switched-on or -off by somatosensory stimuli.
Accessibility: Document exists in file (in attachment to the final report)
Copyright/Reproduction:
By permission
Language:
eng
Author:
Monteiro, C.
Secondary author(s):
Lima, D., Galhardo, V.
Document type:
Article
Number of reproductions:
1
Reference:
Monteiro, C., Lima, D., & Galhardo, V. (2006). Switching-on and -off of bistable spontaneous discharges in rat spinal deep dorsal horn neurons. Neuroscience Letters, 398(3), 258-63. https://doi.org/10.1016/j.neulet.2006.01.008
2-year Impact Factor: 2.092|2006
Times cited: 5|2024-02-05
Indexed document: Yes
Quartile: Q3
Keywords: Strychnine / Formalin / Pain / Oscillations / Multielectrode extracellular recordings
DocumentElectrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy. In Aquém e além do cérebro. Behind and beyond the brain2008

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-168
Location: Arquivo PCA - Pasta 13/2004
Title:
168 - Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy
Duration: 2005-02 - 2007-07
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Dániel Fabó
Institution(s): National Institute of Psychiatry and Neurology, Department of Neurology, Epilepsy Center, Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Diseases/Injuries / Epilepsy / Sleep and dreams

Reference code: PT/FB/BL-2004-168.06
Location: Arquivo PCA - Pasta 13/2004
Title:
Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy. In Aquém e além do cérebro. Behind and beyond the brain
Publication year: 2008
URL:
http://www.bial.com/imagem/Actas_7Simp.pdf
Abstract/Results: ABSTRACT:
Ripples are high-frequency oscillation bursts in the mammalian hippocampus mainly present during Non-
REM sleep. In rodents they occur in association with sharp waves and are grouped by the cortical slow oscillation such that, in parallel with sleep spindles, ripple activity is suppressed during the hyperpolarized down-state and enhanced during the depolarized up-state. The temporal coupling between these oscillations has been suggested to serve a hippocampo-neocortical dialogue underlying memory consolidation during sleep. Here we examined whether a similar coupling exists between these oscillatory phenomena in humans. We based our investigations on epilepsy patients undergoing presurgical evaluation implanted with foramen ovale electrodes. Recording with foramen ovale electrodes is a unique technique allowing parahippocampal electrocorticography in a semi-invasive way. In sleep recordings from seven epileptic patients, scalp-recorded slow oscillations and spindles as well as parahippocampal ripples recorded from foramen ovale electrodes were identified by automatic algorithms. Additionally, ripple and spindle root mean square activity was determined for relevant frequency bands. Ripple activity distinctly decreased time-locked to slow oscillation negative half-waves in the three patients without temporal structural alterations, whereas in the four patients with severe mesiotemporal structural alterations this coupling was obscure. Generally, in the patients ripple activity was increased before spindle peaks and distinctly decreased after the peak. Ripples were consistently associated with interictal spikes suggesting that spike/ripple complexes represent an epileptic transformation of sharp wave/ripple complexes in the epileptic hippocampus. Our findings are consistent with the notion of a hippocampo-to-neocortical information transfer during sleep that is linked to coordinate ripple and spindle activity, and that in the intact temporal lobe is synchronized to cortical slow oscillations.
PUBLICATIONS:
Clemens Z, Mölle M, Eross L, Barsi P, Halász P, Born J. Temporal coupling of parahippocampal ripples, sleep spindles and slow oscillations in humans. 2007 Brain, 130:2868-2878.
Accessibility: Document does not exist in file
Language:
eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Halász, P., Clemens, Z., Borbély, C., & Fabó, D. (2008). Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 7th Symposium of Fundação Bial. Porto: Fundação Bial.
Indexed document: No
Keywords: Hippocampus / Oscillations / Memory consolidation

Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy. In Aquém e além do cérebro. Behind and beyond the brain

Electrocortical studies of the hippocampal-parahippocampal (HP) structures in humans: Foramen ovale (FO) electrodes, as a research tool in human cognition and epilepsy. In Aquém e além do cérebro. Behind and beyond the brain
File348 - Neural basis of mother-child relationship processes: Neural events, theta dynamics, and oxytocin2015-102021-09

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-348
Location: BF-GMS
Title:
348 - Neural basis of mother-child relationship processes: Neural events, theta dynamics, and oxytocin
Duration: 2015-10 - 2021-09
Researcher(s):
Michael J Crowley, Omri Weisman, Richard M. Pasco Fearon, William Moran, Yael Shmueli-Goetz, Lauren Vazquez
Institution(s): Yale University, New Haven, CT (USA)
Abstract/Results: Contents:
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Crowley, M.
Secondary author(s):
Weisman, O., Fearon, P., Moran, W., Shmueli-Goetz, Y., Vazquez, L.
Number of reproductions:
1
Keywords:
Mother-child relationship / Attachment / Oscillations / Oxytocin / Psychophysiology
DocumentInsights into local properties and synchrony of sleep spindles from ECoG in humans 2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-220
Location: Arquivo PCA - Pasta 15/2012
Title:
220 - Consciousness disconnects during sleep
Duration: 2013-04 - 2016-05
Researcher(s):
Giovanni Piantoni
Institution(s): Cortical Physiology Lab, Massachusets General Hospital, Harvard Medical School (USA) and Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final reports
1 article
Submitted papers
Language: eng
Author:
Piantoni, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Sleep and dreams

Reference code: PT/FB/BL-2012-220.03
Location: Arquivo PCA - Pasta 15/2012
Title:
Insights into local properties and synchrony of sleep spindles from ECoG in humans
Publication year: 2014
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=4da09ec6-f098-4bf1-9af3-8457926fe748&cKey=fefbc49d-14b7-4304-a5b2-616c6815d739&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Abstract/Results: ABSTRACT:
During non-REM sleep, neuronal firing is grouped by the slow oscillations at around 1 Hz, and sleep spindles, 0.5-2s long bursts of oscillatory activity between 11 and 18 Hz. Spindles are thought to arise from the interplay between thalamic and cortical neurons and are hypothesized to be involved in a wide variety of fundamental processes including the solidification of learning during sleep. However many of the physiological mechanisms and characteristics of spindles remain poorly understood. The spatial extent of spindle activity, as one key feature, has been the object of substantial debate, with conflicting evidence pointing both to an increase in synchronization, assessed with scalp EEG, and to strong regional localization, as measured by MEG and intraparenchymal depth electrode recordings (iEEG). Here, we examine spindle localization and synchrony across broad areas of neocortex using recordings from, on average, 80 electrodes (ECoG) placed directly on the pial surface in six patients undergoing evaluation for intractable epilepsy. The research was approved by the local institutional review board and electrode placement was determined solely by clinical criteria. At least one hour of visually scored sleep was included in the analysis. Spindles were automatically detected on each electrode independently, based on custom code. Spindles were considered synchronous when two spindles on separate channels overlapped in time. We observed that spindles were more likely than expected by chance to appear at the same time over multiple cortical locations. However, when we estimated the distribution of spindles in relation to the number of active electrodes, we observed that there was a strong positive skew. This indicates that most spindles were synchronous only in one or a few channels at the same time but some spindles were widely distributed. This distinction between focal spindles and distributed spindles was further investigated by measuring the spreading over cortical regions with a 3D reconstruction of the electrode locations and by comparing it with the underlying anatomical structures. These results indicate a dynamic interplay between local properties of focal spindles and widespread synchrony of global spindles. We suggest that the multiple spatial scales at which sleep oscillations operate might provide a flexible framework to support the many functions ascribed to sleep and to spindles in particular, such as sensory gating, memory consolidation, and synaptic homeostasis.
Accessibility: Document does not exist in file
Language:
eng
Author:
Piantoni, G.
Secondary author(s):
Halgren, E., Cash, S.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Piantoni, G., Halgren, E., & Cash, S. (2014, November). Insights into local properties and synchrony of sleep spindles from ECoG in humans. Poster presented at the 2014 Society for Neuroscience meeting, Washington, D. C. Abstract retrieved from http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=4da09ec6-f098-4bf1-9af3-8457926fe748&cKey=fefbc49d-14b7-4304-a5b2-616c6815d739&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Indexed document: No
Keywords: Sleep / Electrophysiology / Oscillations
DocumentInvolvement of phasic brainstem activity in the preferential anterior-to-posterior direction of traveling cortical slow waves in human sleep EEG 2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-220
Location: Arquivo PCA - Pasta 15/2012
Title:
220 - Consciousness disconnects during sleep
Duration: 2013-04 - 2016-05
Researcher(s):
Giovanni Piantoni
Institution(s): Cortical Physiology Lab, Massachusets General Hospital, Harvard Medical School (USA) and Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final reports
1 article
Submitted papers
Language: eng
Author:
Piantoni, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Sleep and dreams

Reference code: PT/FB/BL-2012-220.04
Location: Arquivo PCA - Pasta 15/2012
Title:
Involvement of phasic brainstem activity in the preferential anterior-to-posterior direction of traveling cortical slow waves in human sleep EEG
Publication year: 2014
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=839ccbfd-050c-4315-b1eb-4b593af117b8&cKey=36a00cdf-d67d-4c90-ab1a-dff420912256&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Abstract/Results: ABSTRACT:
The slow waves of sleep arise from the alternation of periods of relative neuronal silence and periods of high neuronal activity. Intriguingly, slow waves travel preferentially from anterior to posterior cortical regions. It has been proposed that phasic activity of subcortical regions that modulate cortical excitability may be involved in state transitions. The neuronal mechanisms contributing to the directional preference of traveling however remain elusive. Since the active phase of the cortical slow wave can be preceded by phasic activity in the locus coeruleus (LC), we hypothesized that the LC, due to the anteroposterior gradient of the length and consequently axonal propagation duration of its cortically projecting fibers, might depolarize frontal cortical neurons slightly earlier than more posterior neurons and thus prime the cortex for a preferential propagation of slow waves along the anterior-to-posterior axis. High-density electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI) were recorded in 14 participants while sleeping. Slow waves were automatically detected and classified according to their direction of propagation on the scalp as traveling either in the anterior-to-posterior or posterior-to-anterior direction. Statistical parameter mapping (SPM) analysis was used to evaluate to which extent these two event types were preceded by phasic activation in the brainstem. A brainstem area compatible with the right LC was significantly activated in association with slow waves traveling in the anterior-to-posterior direction, but not significantly with slow waves traveling in the opposite, posterior-to-anterior, direction. Phasic activity in the LC may thus contribute to the bias of slow waves to travel in an anterior-to-posterior direction.
Accessibility: Document does not exist in file
Language:
eng
Author:
Van Someren, E.
Secondary author(s):
Piantoni, G., Stoffers, D., Van Der Werf, Y., Dang-Vu, T., Maquet, P.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Van Someren, E., Piantoni, G., Stoffers, D., Van Der Werf, Y., Dang-Vu, T., & Maquet, P. (2014, November). Involvement of phasic brainstem activity in the preferential anterior-to-posterior direction of traveling cortical slow waves in human sleep EEG. Paper presented at the 2014 Society for Neuroscience meeting, Washington, D. C. Abstract retrieved from http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=839ccbfd-050c-4315-b1eb-4b593af117b8&cKey=36a00cdf-d67d-4c90-ab1a-dff420912256&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Indexed document: No
Keywords: Sleep / Locus coeruleus / Oscillations
DocumentDissociation between amplitude and synchrony of brain activity in a human model of loss of coherence2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-132
Location: Arquivo PCA - Pasta 11/2012
Title:
132 - A direct test of the binding by synchrony hypothesis in humans: the neural correlates of coherent object perception
Duration: 2013-11 - 2016-01
Researcher(s):
Miguel Castelo-Branco, Maria Ribeiro, João Duarte, Gabriel Costa
Institution(s): IBILI, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress reports
Final report
Article
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Ribeiro, M., Duarte, J., Costa, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Perception / Brain structure and function

Reference code: PT/FB/BL-2012-132.13
Location: Arquivo PCA - Pasta 11/2012
Title:
Dissociation between amplitude and synchrony of brain activity in a human model of loss of coherence
Publication year: 2014
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=44b49305-57b1-4f13-8b1a-4918517cf24d&cKey=380ee307-f56e-45fe-92eb-1ba81f66558a&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Abstract/Results: ABSTRACT:
The central coherence hypothesis was proposed to explain abnormal cognition in ASD and Williams syndrome (WS), a neurodevelopmental disorder linked with autism, and the most clearcut model for impaired central coherence. We studied this model of impaired holistic processing to test a functional role for neural synchrony using EEG and a set of experimental tasks requiring visual integration at different complexity levels. We tested whether synchronization and amplitude modulation of gamma patterns can be segregated in this model. We used a set of experimental tasks requiring feature integration at different complexity levels (static and motion, 2D and 3D face stimuli) and compared gamma-band activity and synchrony between WS patients (n=9; 21.44 ± 2.30 years) and a normal control group. WS diagnostic was confirmed based on clinical and genetic criteria. Control participants (n=8) were matched on chronological age, gender and handedness. EEG was recorded using a SynAmps2 64 channel system, at 2kHz and processed offline. Data were corrected and segmented into epochs locked to the stimulus onset (-0.5s to 1.5s) for all conditions. Time-frequency (TF) and phase synchrony analysis were performed as in Uhlhaas et al., 2006. TF analysis was carried out in Matlab® across distinct defined electrode clusters (Parietal, Temporal, Parieto-Occipital and Occipital) for frequencies ranging from 10Hz to 90Hz. Phase-locking values (PLV) were computed between all possible pairs of electrodes, and the stability of phase differences was evaluated through all the trials. For the statistical comparison between groups, Wilcoxon ranksum tests were carried out including false discovery rate (FDR) correction for multiple comparisons. Groups differed (p<0.02 FDR corrected) in three main frequency sub-bands: controls showed higher synchrony at 10-22Hz and 30-43Hz and WS showed increased synchrony for the 62-79Hz frequency band. The condition requiring the highest level of integration (SFM) was the one associated with the most dramatic loss of synchrony in the WS group. This suggests a dependence on visual complexity and integration requirements and is in line with the proposal that perception requires mechanisms for integration and feature binding that rely on the neuronal synchrony. Moreover, synchrony was reduced in WS across stimulus conditions in striking contrast with increased amplitude modulation at 25-45Hz. This signature of dramatic loss of synchrony as opposed to concomitantly increased activation (amplitude), provides evidence that synchrony underlies central coherence irrespective of power changes in gamma activity.
Accessibility: Document does not exist in file
Language:
eng
Author:
Castelhano, J.
Secondary author(s):
Bernardino, I., Rebola, J., Castelo-Branco, M.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Castelhano, J., Bernardino, I., Rebola, J., & Castelo-Branco, M. (2014, November). Dissociation between amplitude and synchrony of brain activity in a human model of loss of coherence. Poster presented at Society for Neuroscience 2014, Washington, DC. Online abstract available at http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=44b49305-57b1-4f13-8b1a-4918517cf24d&cKey=380ee307-f56e-45fe-92eb-1ba81f66558a&mKey=54c85d94-6d69-4b09-afaa-502c0e680ca7
Indexed document: No
Keywords: Electrophysiology / Oscillations / Synchrony
DocumentBinding of ambiguous visual stimuli is associated with changes in beta power but not with synchrony2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-373
Location: BF-GMS
Title:
373 - Multimodal Mapping of Visual Motion Perceptual Decision: Dissecting the Role of Different Motion Integration Areas in Visual Surface Reconstruction
Duration: 2016-02 - 2017-10
Researcher(s):
Miguel de Sá e Sousa de Castelo Branco, Gabriel Nascimento Ferreira da Costa, Gilberto Silva, João Valente Duarte, Ricardo Martins
Institution(s): ICNAS - Institute for Nuclear Sciences Applied to Health, Coimbra, Portugal; IBILI - Institute for Biomedical Imaging and Life Sciences, Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Author: Castelo-Branco, M.
Secondary author(s):
Costa, G., Silva, G., Duarte, J., Martins, R.
Number of reproductions:
1
Keywords:
Motion perception / Decision-making / Perceptual Ambiguity / Decision Models / Psychophysiology

Reference code: PT/FB/BL-2014-373.03
Location: BF-GMS
Title:
Binding of ambiguous visual stimuli is associated with changes in beta power but not with synchrony
Publication year: 2016
URL:
https://ww5.aievolution.com/hbm1601/index.cfm?do=abs.viewAbs&abs=2992
Abstract/Results: ABSTRACT:
INTRODUCTION
In vision, perceptual features are processed in several regions distributed across the brain. Yet the brain achieves a coherent perception of visual scenes and objects through integration of features that are encoded in spatially segregated brain areas. How the brain seamlessly achieves this accurate integration is currently unknown and is referred to as the "binding problem" (Von der Malsburg, 1981). Among the proposed mechanisms meant to resolve the binding problem, the binding-by-synchrony hypothesis (BBS) proposes that binding is carried out through the synchronous discharge of different neuronal assemblies (Singer & Gray, 1995). The present study aimed at providing a critical test to the BBS hypothesis by evaluating long range connectivity during a motion integration visual task that entails binding across hemispheres.
METHODS
EEG (58 channels) was recorded while participants observed an ambiguous stimulus that could be perceived in either a "bound" configuration, requiring visual integration across hemispheres, or an "unbound" configuration, where the images at each hemifield were perceived as being separate (Wallach, 1935; English translation in Wuerger et al., 1996). Participants reported continuously their perceptual decision. 21 subjects performed this task.
RESULTS
Synchrony between neural populations belonging to distinct hemispheres was estimated using the imaginary part of coherency (ImCoh) in search of a correlation between interhemispheric synchrony and perceptual binding. We found no evidence of increased synchrony during periods of bound perception, compared to unbound, at alpha (8-12 Hz), beta (13-30 Hz) or gamma frequencies (> 30 Hz) and perceptual changes were not accompanied by changes in ImCoh. The distinct visual experiences showed, nonetheless, differences in power, particularly at the beta frequency range (12-23 Hz) over parietal regions. Moreover, around the moment of perceptual switches, changes in alpha and beta power provided clear neurophysiological correlates of a change in visual experience, with an increase in beta oscillations indicating a change towards a bound configuration.
CONCLUSIONS
Our findings reveal that the visual experience of binding can be identified by distinct signatures of oscillatory activity, regardless of long range synchrony. In our current paradigm, visual binding occurred under ambiguous conditions, but integration of visual information across hemifields was found not to correlate with increased synchrony across hemispheres. On the other hand, spectral signatures of increased power at beta frequencies were found to correlate with the perception of the bound stimulus. When the bound configuration was the dominant percept, beta activity was increased compared to the unbound perception, with greater differences found over parietal regions. This suggests that the ambiguity might be resolved at hierarchically higher cortical areas without the need for synchronous activity at lower visual ones.
Accessibility: Document does not exist in file
Language:
eng
Author:
Costa, G.
Secondary author(s):
Duarte, J., Martins, R., Castelo-Branco, M.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Costa, G., Duarte, J., Martins, R., & Castelo-Branco, M. (2016, June). Binding of ambiguous visual stimuli is associated with changes in beta power but not with synchrony. Poster presented at the 22nd Annual Meeting of the Organization for Human Brain Mapping, Geneve, Switzwerland. Abstract retrieved at https://ww5.aievolution.com/hbm1601/index.cfm?do=abs.viewAbs&abs=2992
Indexed document: No
Keywords: Electroencephalogram (EEG) / Vision / Binding / Synchrony / Oscillations
DocumentAstrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-207
Location: BF-GMS
Title:
207 - The role of astrocytes in complex cognitive processing
Duration: 2015-10
Researcher(s):
João Filipe Pedreira de Oliveira, Joana Correia, Joana Marques, Luísa Pinto, Nuno Dias, Sónia Guerra Gomes, Vanessa Sardinha, Inês Caetano Campos
Institution(s): ICVS/3B's Laboratório Associado - Universidade do Minho, Braga (Portugal)
Contents: Contents:
Application form
Correspondence
Author: Oliveira, J. F.
Secondary author(s):
Correia, J., Marques, J., Pinto, L., Dias, N., Gomes, S., Sardinha, V.
Number of reproductions:
1
Keywords:
Psychophysiology

Reference code: PT/FB/BL-2014-207.02
Location: BF-GMS
Title:
Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function
Publication year: 2017
URL:
http://onlinelibrary.wiley.com/doi/10.1002/glia.23205/abstract
Abstract/Results: ABSTRACT:
Astrocytes interact with neurons at the cellular level through modulation of synaptic formation, maturation, and function, but the impact of such interaction into behavior remains unclear. Here, we studied the dominant negative SNARE (dnSNARE) mouse model to dissect the role of astrocyte-derived signaling in corticolimbic circuits, with implications for cognitive processing. We found that the blockade of gliotransmitter release in astrocytes triggers a critical desynchronization of neural theta oscillations between dorsal hippocampus and prefrontal cortex. Moreover, we found a strong cognitive impairment in tasks depending on this network. Importantly, the supplementation with d-serine completely restores hippocampal-prefrontal theta synchronization and rescues the spatial memory and long-term memory of dnSNARE mice. We provide here novel evidence of long distance network modulation by astrocytes, with direct implications to cognitive function.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2014-427.02
Author: Sardinha, V. M.
Secondary author(s):
Guerra-Gomes, S., Caetano, I., Tavares, G., Martins, M., Reis, J. S., Correia, J. S., Teixeira-Castro, A., Pinto, L., Sousa, N., Oliveira, J. F.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Sardinha, V. M., Martins, M., Reis, J. S., Correia, J. S., Teixeira-Castro, A., ..., Oliveira, J. F. (2017). Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function. Glia, 65(12), 1-17. https://doi.org/10.1002/glia.23205
2-year Impact Factor: 5.846|2017
Times cited: 60|2024-02-08
Indexed document: Yes
Quartile: Q1
Keywords: Astrocyte / Behavior / Local field potential / Neuronal morphology / Oscillations
DocumentAstrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-427
Location: BF-GMS
Title:
427 - Gliogenesis control of brain neuroplasticity, neurophysiology and cognitive function
Duration: 2015-09
Researcher(s):
Luísa Alexandra Meireles Pinto, Ana Rita Machado dos Santos, António Maria Restolho Mateus Pinheiro, Cristina Joana Moreira Marques, Joana Sofia da Silva Correia, João Filipe Pedreira de Oliveira, João Miguel Bessa Peixoto, Nuno Dinis Alves, Patrícia Carvalho Patrício, Vítor Manuel da Silva Pinto
Institution(s): Life and Health Sciences Research Institute - ICVS, University of Minho and ICVS/3B's- Government Associate Laboratory, Braga (Portugal); Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Language: eng
Author:
Pinto, L.
Secondary author(s):
Santos, A., Pinho, A., Marques, A., Correia, J., Oliveira, J. F., Peixoto, J., Alves, N., Patrício, P., Pinto, V.
Number of reproductions:
1
Keywords:
Astrogliogenesis / Neuroplasticity / Cognition / Electrophysiology / Psychophysiology

Reference code: PT/FB/BL-2014-427.02
Location: BF-GMS
Title:
Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function
Publication year: 2017
URL:
http://onlinelibrary.wiley.com/doi/10.1002/glia.23205/abstract
Abstract/Results: ABSTRACT:
Astrocytes interact with neurons at the cellular level through modulation of synaptic formation, maturation, and function, but the impact of such interaction into behavior remains unclear. Here, we studied the dominant negative SNARE (dnSNARE) mouse model to dissect the role of astrocyte-derived signaling in corticolimbic circuits, with implications for cognitive processing. We found that the blockade of gliotransmitter release in astrocytes triggers a critical desynchronization of neural theta oscillations between dorsal hippocampus and prefrontal cortex. Moreover, we found a strong cognitive impairment in tasks depending on this network. Importantly, the supplementation with d-serine completely restores hippocampal-prefrontal theta synchronization and rescues the spatial memory and long-term memory of dnSNARE mice. We provide here novel evidence of long distance network modulation by astrocytes, with direct implications to cognitive function.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2014-207.02
Author: Sardinha, V. M.
Secondary author(s):
Martins, M., Reis, J. S., Correia, J. S., Teixeira-Castro, A., Pinto, L., Sousa, N., Oliveira, J. F.
Document type:
Article-d
Number of reproductions:
1
Reference:
Sardinha, V. M., Martins, M., Reis, J. S., Correia, J. S., Teixeira-Castro, A., ..., Oliveira, J. F. (2017). Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function. Glia, 65(12), 1-17. https://doi.org/10.1002/glia.23205
2-year Impact Factor: 5.846|2017
Times cited: 60|2024-02-08
Indexed document: Yes
Quartile: Q1
Keywords: Astrocyte / Behavior / Local field potential / Neuronal morphology / Oscillations
DocumentFinal report - Neural oscillations underlie individual differences in brightness perception2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-535
Location: BF-GMS
Title:
535 - Neural oscillations underlie individual differences in brightness perception
Duration: 2015-11 - 2021-07
Researcher(s):
James Stuart Peter Macdonald
Institution(s): University of Roehampton, London (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
MacDonald, J. S. P.
Number of reproductions:
1
Keywords:
Vision / Perception / Brightness / Oscillation / Psychophysiology

Reference code: PT/FB/BL-2014-535.01
Location: BF-GMS
Title:
Final report - Neural oscillations underlie individual differences in brightness perception
Publication year: 2019
URL:
https://www.bial.com/media/3762/neural-oscillations-underlie-individual-differences-in-brightness-perception.pdf
Abstract/Results: ABSTRACT:
EEG recordings of human occipital alpha-band oscillations have been strongly linked to visual perception. In particular, cortical excitability is increased in areas exhibiting low alpha amplitude. Although the frequency of alpha oscillations varies significantly between individuals, it has only rarely been studied as an independent factor in shaping perception. Temporal integration of successive stimuli has recently been shown to depend on individual alpha oscillation frequency, with faster frequencies resulting in finer temporal resolution in perception. This suggests that perception may qualitatively differ between individuals with different spontaneous alpha frequencies. Moreover, underlying the differences in temporal resolution may be a more basic visual process: differences in sensitivity to visual flicker. We tested this hypothesis by correlating performance in a flicker detection task with the speed of individual alpha rhythms. For each participant, we obtained temporal contrast sensitivity functions and related the stimulus frequency at peak sensitivity to individual alpha frequency. Our results demonstrate that individual alpha frequency predicts contrast sensitivity to visual flicker. Individuals with faster spontaneous alpha rhythms were maximally sensitive at faster stimulus flicker frequencies. Importantly, such individuals performed worse at slower stimulus frequencies than those with naturally slower alpha rhythms. This suggests that individual alpha frequency specifically predicts the stimulus flicker frequency which produces maximum contrast sensitivity. The findings provide evidence for a link between alpha frequency and individual differences in basic, low-level visual perception.
Accessibility: Document exists in file
Language:
eng
Author:
MacDonald, J.
Document type:
Final report
Number of reproductions:
1
Reference:
MacDonald, J. (2019). Final report - Neural oscillations underlie individual differences in brightness perception.
Indexed document: No
Keywords: Electroencephalogram (EEG) / Oscillations / Alpha / Visual / Perception

Final report - Neural oscillations underlie individual differences in brightness perception

Final report - Neural oscillations underlie individual differences in brightness perception
DocumentThe anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-132
Location: Arquivo PCA - Pasta 11/2012
Title:
132 - A direct test of the binding by synchrony hypothesis in humans: the neural correlates of coherent object perception
Duration: 2013-11 - 2016-01
Researcher(s):
Miguel Castelo-Branco, Maria Ribeiro, João Duarte, Gabriel Costa
Institution(s): IBILI, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Progress reports
Final report
Article
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Ribeiro, M., Duarte, J., Costa, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Perception / Brain structure and function

Reference code: PT/FB/BL-2012-132.19
Location: Arquivo PCA - Pasta 11/2012
Title:
The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study
Publication year: 2016
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036430/
Abstract/Results: ABSTRACT:
Introduction:
Hippocampal oscillations have been regularly described as playing a dominant role in spatial memory and navigation in rodents. In humans, the relative role of anterior versus posterior rhythms during navigational memory is not established.
Methods: Here, we tested this hypothesis using direct brain ECoG recordings in the anterior and posterior hippocampus of a patient, in a navigational task requiring spatial memory. We assessed multiple oscillatory bands during encoding and retrieval phases.
Results: We found navigation related 1-3.5 Hz activity during retrieval, both in the anterior and posterior hippocampus. Activity between 4 and 8 Hz was identified during both encoding and retrieval, only in the anterior hippocampus.
Conclusions: Our findings are consistent with the view that an anterior/posterior functional gradient is present in the hippocampus, and involves two distinct neuronal networks, supporting either encoding or retrieval processes. Although this is a single case scenario, these findings suggest that neural oscillations during spatial navigation do vary across hippocampal subregions, as a function of encoding versus retrieval processes during the mnemonic process. In this single case study, the results point to the presence of a dual involvement of multiple frequency bands across hippocampal subregions during encoding and retrieval. Although these results need generalization, they provide a new perspective on distinct physiological properties of the anterior and posterior hippocampus in human spatial navigation during encoding and retrieval.
Accessibility: Document exists in file
Language:
eng
Related objects:
BL-2012-133.16
Author: Duarte, I. C.
Secondary author(s):
Castelhano, J. , Sales, F. , Castelo-Branco, M.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Duarte, I. C., Castelhano, J., Sales, F., & Castelo-Branco, M. (2016). The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study. Brain and behavior, 6(9), e00507. https://doi.org/10.1002/brb3.507
2-year Impact Factor: 2.157|2016
Times cited: 6|2024-02-07
Indexed document: Yes
Quartile: Q3
Keywords: Delta / Electrocorticography / Hippocampus / Oscillations / Theta

The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study

The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study
DocumentThe anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-133
Location: Arquivo PCA - Pasta 9/2012
Title:
133 - The role of the core and extended face networks in visual perception and high level social cognition
Duration: 2013-11 - 2016-01
Researcher(s):
Miguel Castelo-Branco, Marco Simões, Carlos Amaral, Gregor Philipiak, José Rebola, João Castelhano
Institution(s): IBILI, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Language: eng
Author:
Castelo-Branco, M.
Secondary author(s):
Simões, M., Amaral, C., Philipiak, G., Rebola, J., Castelhano, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Perception / Attention / Affective and social behavior / Social cognition / Brain structure and function

Reference code: PT/FB/BL-2012-133.16
Location: Arquivo PCA - Pasta 9/2012
Title:
The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study
Publication year: 2016
URL:
https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.507
Abstract/Results: ABSTRACT:
Introduction:
Hippocampal oscillations have been regularly described as playing a dominant role in spatial memory and navigation in rodents. In humans, the relative role of anterior versus posterior rhythms during navigational memory is not established.
Methods: Here, we tested this hypothesis using direct brain ECoG recordings in the anterior and posterior hippocampus of a patient, in a navigational task requiring spatial memory. We assessed multiple oscillatory bands during encoding and retrieval phases.
Results: We found navigation related 1-3.5 Hz activity during retrieval, both in the anterior and posterior hippocampus. Activity between 4 and 8 Hz was identified during both encoding and retrieval, only in the anterior hippocampus.
Conclusions: Our findings are consistent with the view that an anterior/posterior functional gradient is present in the hippocampus, and involves two distinct neuronal networks, supporting either encoding or retrieval processes. Although this is a single case scenario, these findings suggest that neural oscillations during spatial navigation do vary across hippocampal subregions, as a function of encoding versus retrieval processes during the mnemonic process. In this single case study, the results point to the presence of a dual involvement of multiple frequency bands across hippocampal subregions during encoding and retrieval. Although these results need generalization, they provide a new perspective on distinct physiological properties of the anterior and posterior hippocampus in human spatial navigation during encoding and retrieval.
Accessibility: Document exists in file
Language:
eng
Related objects:
BL-2012-132.19
Author: Duarte, I. C.
Secondary author(s):
Castelhano, J., Sales, F., Castelo-Branco, M.
Document type:
Article-d
Number of reproductions:
1
Reference:
Duarte, I. C., Castelhano, J., Sales, F., & Castelo-Branco, M. (2016). The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study. Brain and behavior, 6(9), e00507. https://doi.org/10.1002/brb3.507
2-year Impact Factor: 2.157|2016
Times cited: 6|2024-02-07
Indexed document: Yes
Quartile: Q3
Keywords: Delta / Electrocorticography / Hippocampus / Oscillations / Theta

The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study

The anterior versus posterior hippocampal oscillations debate in human spatial navigation: evidence from an electrocorticographic case study
DocumentIncreasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-044
Location: BF-GMS
Title:
044 - Inducing and measuring plasticity in response control mechanisms in the human brain
Duration: 2017-10 - 2021-09
Researcher(s):
Alejandra Sel de Felipe, Matthew Rushworth
Institution(s): Department of Experimental Psychology, University of Oxford (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Sel, A.
Secondary author(s):
Rushworth, M.
Number of reproductions:
1
Keywords:
Cognitive control / Response inhibition / Cortical plasticity / Neurostimulation / Psychophysiology

Reference code: PT/FB/BL-2016-044.04
Location: BF-GMS
Title:
Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain
Publication year: 2021
URL:
https://www.pnas.org/content/118/37/e2100652118
Abstract/Results: ABSTRACT:
The origins of oscillatory activity in the brain are currently debated, but common to many hypotheses is the notion that they reflect interactions between brain areas. Here, we examine this possibility by manipulating the strength of coupling between two human brain regions, ventral premotor cortex (PMv) and primary motor cortex (M1), and examine the impact on oscillatory activity in the motor system measurable in the electroencephalogram. We either increased or decreased the strength of coupling while holding the impact on each component area in the pathway constant. This was achieved by stimulating PMv and M1 with paired pulses of transcranial magnetic stimulation using two different patterns, only one of which increases the influence exerted by PMv over M1. While the stimulation protocols differed in their temporal patterning, they were comprised of identical numbers of pulses to M1 and PMv. We measured the impact on activity in alpha, beta, and theta bands during a motor task in which participants either made a preprepared action (Go) or withheld it (No-Go). Augmenting cortical connectivity between PMv and M1, by evoking synchronous pre- and postsynaptic activity in the PMv–M1 pathway, enhanced oscillatory beta and theta rhythms in Go and No-Go trials, respectively. Little change was observed in the alpha rhythm. By contrast, diminishing the influence of PMv over M1 decreased oscillatory beta and theta rhythms in Go and No-Go trials, respectively. This suggests that corticocortical communication frequencies in the PMv–M1 pathway can be manipulated following Hebbian spike-timing–dependent plasticity.
Accessibility: Document exists in file
Language:
eng
Author:
Sel, A.
Secondary author(s):
Verhagen, L., Angerer, K., David, R., Klein-Flügge, M. C., Rushworth, M.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Sel, A., Verhagen, L., Angerer, K., David, R., Klein-Flügge, M. C., & Rushworth, M. (2021). Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain. Proceedings of the National Academy of Sciences of the United States of America, 118(37), e2100652118. https://doi.org/10.1073/pnas.2100652118
2-year Impact Factor: 11.779|2021
Times cited: 11|2024-02-14
Indexed document: Yes
Quartile: Q1
Keywords: Action control / Transcranial magnetic stimulation / Ventral premotor cortex / Primary motor / Cortex / Oscillations

Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain

Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain
DocumentAcross-area synchronization supports feature integration in a biophysical network model of working memory2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-356
Location: BF-GMS
Title:
356 - Neural mechanisms underlying unconscious working memory
Duration: 2019-05 - 2021-09
Researcher(s):
Albert Compte, João Barbosa, Josep Valls-Sole
Institution(s): Institut d'investigacions Biomèdiques August Pi i Sunyer - IDIBAPS, Barcelona (Spain)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Compte, A.
Secondary author(s):
Barbosa, J., Valls-Sole, J.
Number of reproductions:
1
Keywords:
Working memory / Consciousness / Transcranial magnetic stimulation (TMS) / Psychophysiology

Reference code: PT/FB/BL-2018-356.06
Location: BF-GMS
Title:
Across-area synchronization supports feature integration in a biophysical network model of working memory
Publication year: 2021
URL:
https://www.frontiersin.org/articles/10.3389/fncir.2021.716965/full
Abstract/Results: ABSTRACT:
Working memory function is severely limited. One key limitation that constrains the ability to maintain multiple items in working memory simultaneously is so-called swap errors. These errors occur when an inaccurate response is in fact accurate relative to a non-target stimulus, reflecting the failure to maintain the appropriate association or “binding” between the features that define one object (e.g., color and location). The mechanisms underlying feature binding in working memory remain unknown. Here, we tested the hypothesis that features are bound in memory through synchrony across feature-specific neural assemblies. We built a biophysical neural network model composed of two one-dimensional attractor networks – one for color and one for location – simulating feature storage in different cortical areas. Within each area, gamma oscillations were induced during bump attractor activity through the interplay of fast recurrent excitation and slower feedback inhibition. As a result, different memorized items were held at different phases of the network’s oscillation. These two areas were then reciprocally connected via weak cortico-cortical excitation, accomplishing binding between color and location through the synchronization of pairs of bumps across the two areas. Encoding and decoding of color-location associations was accomplished through rate coding, overcoming a long-standing limitation of binding through synchrony. In some simulations, swap errors arose: “color bumps” abruptly changed their phase relationship with “location bumps.” This model, which leverages the explanatory power of similar attractor models, specifies a plausible mechanism for feature binding and makes specific predictions about swap errors that are testable at behavioral and neurophysiological levels.
Accessibility: Document exits in file
Language:
eng
Author:
Barbosa, J.
Secondary author(s):
Babushkin, V., Temudo, A., Sreenivasan, K. K., Compte, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Barbosa, J., Babushkin, V., Temudo, A., Sreenivasan, K. K., & Compte, A. (2021). Across-area synchronization supports feature integration in a biophysical network model of working memory. Frontiers in Neural Circuits, 15, 716965. https://doi.org/10.3389/fncir.2021.716965
2-year Impact Factor: 3.342|2021
Times cited: 2|2024-02-14
Indexed document: Yes
Quartile: Q3
Keywords: Working memory / Binding / Oscillations / Multi-area / Attractor network

Across-area synchronization supports feature integration in a biophysical network model of working memory

Across-area synchronization supports feature integration in a biophysical network model of working memory
DocumentParietal alpha oscillatory peak frequency mediates the effect of practice on visuospatial working memory performance2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-204
Location: BF-GMS
Title:
204 - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway
Duration: 2019-03 - 2023-04
Researcher(s):
Vincenzo Romei
Institution(s): Centre for studies and research in Cognitive Neuroscience - CsrNC, Department of Psychology, University of Bologna (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Romei, V.
Secondary author(s):
Poch, C.
Number of reproductions:
1
Keywords:
Brain oscillations / Working memory / Functional connectivity / Neurostimulation / Psychophysiology

Reference code: PT/FB/BL-2018-204.16
Location: BF-GMS
Title:
Parietal alpha oscillatory peak frequency mediates the effect of practice on visuospatial working memory performance
Publication year: 2022
URL:
https://www.mdpi.com/2411-5150/6/2/30/htm
Abstract/Results: Visuospatial working memory (WM) requires the activity of a spread network, including right parietal regions, to sustain storage capacity, attentional deployment, and active manipulation of information. Notably, while the electrophysiological correlates of such regions have been explored using many different indices, evidence for a functional involvement of the individual frequency peaks in the alpha (IAF) and theta bands (ITF) is still poor despite their relevance in many influential theories regarding WM. Interestingly, there is also a parallel lack of literature about the effect of short-term practice on WM performance. Here, we aim to clarify whether the simple repetition of a change-detection task might be beneficial to WM performance and to which degree these effects could be predicted by IAF and ITF. For this purpose, 25 healthy participants performed a change-detection task at baseline and in a retest session, while IAF and ITF were also measured. Results show that task repetition improves WM performance. In addition, right parietal IAF, but not ITF, accounts for performance gain such that faster IAF predicts higher performance gain. Our findings align with recent literature suggesting that the faster the posterior alpha, the finer the perceptual sampling rate, and the higher the WM performance gain.
Accessibility: Document exists in file
Language:
eng
Author:
Bertaccini, R.
Secondary author(s):
Ellena, G., Macedo-Pascual, J., Carusi, F., Trajkovic, J., Poch, C., Romei, V.
Document type:
Article
Number of reproductions:
1
Reference:
Bertaccini, R., Ellena, G., Macedo-Pascual, J., Carusi, F., Trajkovic, J., Poch, C., & Romei, V. (2022). Parietal alpha oscillatory peak frequency mediates the effect of practice on visuospatial working memory performance. Vision, 6(30). https://doi.org/10.3390/vision6020030
2-year Impact Factor: N/A
Times cited: N/A
Indexed document: Yes
Quartile: N/A
Keywords: Working memory / Oscillations / Theta / Alpha / Individual peak frequency / Inverse efficiency score / Practice

Parietal alpha oscillatory peak frequency mediates the effect of practice on visuospatial working memory performance

Parietal alpha oscillatory peak frequency mediates the effect of practice on visuospatial working memory performance
DocumentChanging connectivity between premotor and motor cortex changes inter-areal communication in the human brain2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-044
Location: BF-GMS
Title:
044 - Inducing and measuring plasticity in response control mechanisms in the human brain
Duration: 2017-10 - 2021-09
Researcher(s):
Alejandra Sel de Felipe, Matthew Rushworth
Institution(s): Department of Experimental Psychology, University of Oxford (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Sel, A.
Secondary author(s):
Rushworth, M.
Number of reproductions:
1
Keywords:
Cognitive control / Response inhibition / Cortical plasticity / Neurostimulation / Psychophysiology

Reference code: PT/FB/BL-2016-044.05
Location: BF-GMS
Title:
Changing connectivity between premotor and motor cortex changes inter-areal communication in the human brain
Publication year: 2023
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0301008223000886?via%3Dihub
Abstract/Results: ABSTRACT:
The ventral premotor cortex (PMv) is an important component of cortico-cortical pathways mediating prefrontal control over primary motor cortex (M1) function. Paired associative stimulation (ccPAS) is known to change PMv influence over M1 in humans, which manifests differently depending on the behavioural context. Here we show that these changes in influence are functionally linked to PMv-M1 phase synchrony changes induced by repeated paired stimulation of the two areas. PMv-to-M1 ccPAS leads to increased phase synchrony in alpha and beta bands, while reversed order M1-to-PMv ccPAS leads to decreased theta phase synchrony. These changes are visible at rest but are predictive of changes in oscillatory power in the same frequencies during movement execution and inhibition, respectively. The results unveil a link between the physiology of the motor network and the resonant frequencies mediating its interactions and provide a putative mechanism underpinning the relationship between synaptic efficacy and brain oscillations.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Trajkovic, J.
Secondary author(s):
Romei, V., Rushworth, M. F. S., Sel, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Trajkovic, J., Romei, V., Rushworth, M. F. S., & Sel, A. (2023). Changing connectivity between premotor and motor cortex changes inter-areal communication in the human brain. Progress in Neurobiology, 228, 102487. https://doi.org/10.1016/j.pneurobio.2023.102487
2-year Impact Factor: 6.7|2023
Times cited: 2|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Communication through coherence / Cortico-cortical paired associative stimulation / Oscillations / Primary motor cortex / Transcranial magnetic stimulation (TMS) / Ventral pre-motor cortex
DocumentDistinct oscillatory patterns differentiate between segregation and integration processes in perceptual grouping2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-207
Location: BF-GMS
Title:
207 - The role of motion adaptation in bottom-up mechanisms of perceptual decision-making
Duration: 2017-11
Researcher(s):
Miguel Castelo-Branco, João Duarte, Ricardo Martins, Teresa Sousa, Gabriel Costa
Institution(s): Institute for Nuclear Sciences Applied to Health - ICNAS, University of Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Author: Castelo-Branco, M.
Secondary author(s):
Duarte, J., Martins, R., Sousa, T., Costa, G.
Number of reproductions:
1
Keywords:
Adaptation / Neuroimaging / Perceptual decision / Electroencephalogram (EEG) / Psychophysiology

Reference code: PT/FB/BL-2016-207.11
Location: BF-GMS
Title:
Distinct oscillatory patterns differentiate between segregation and integration processes in perceptual grouping
Publication year: 2024
URL:
https://doi.org/10.1002/hbm.26779
Abstract/Results: ABSTRACT:
Recently, there has been a resurgence in experimental and conceptual efforts to understand how brain rhythms can serve to organize visual information. Oscillations can provide temporal structure for neuronal processing and form a basis for integrating information across brain areas. Here, we use a bistable paradigm and a data-driven approach to test the hypothesis that oscillatory modulations associate with the integration or segregation of visual elements. Spectral signatures of perception of bound and unbound configurations of visual moving stimuli were studied using magnetoencephalography (MEG) in ambiguous and unambiguous conditions. Using a 2 × 2 design, we were able to isolate correlates from visual integration, either perceptual or stimulus-driven, from attentional and ambiguity-related activity. Two frequency bands were found to be modulated by visual integration: an alpha/beta frequency and a higher frequency gamma-band. Alpha/beta power was increased in several early visual cortical and dorsal visual areas during visual integration, while gamma-band power was surprisingly increased in the extrastriate visual cortex during segregation. This points to an integrative role for alpha/beta activity, likely from top-down signals maintaining a single visual representation. On the other hand, when more representations have to be processed in parallel gamma-band activity is increased, which is at odds with the notion that gamma oscillations are related to perceptual coherence. These modulations were confirmed in intracranial EEG recordings and partially originate from distinct brain areas. Our MEG and stereo-EEG data confirms predictions of binding mechanisms depending on low-frequency activity for long-range integration and for organizing visual processing while refuting a straightforward correlation between gamma-activity and perceptual binding. PRACTITIONER POINTS: Distinct neurophysiological signals underlie competing bistable percepts. Increased alpha/beta activity correlate with visual integration while gamma correlates with segmentation. Ambiguous percepts drive alpha/beta activity in the posterior cingulate cortex.
Accessibility: Document exists in file
Language:
eng
Author:
Costa, G. N.
Secondary author(s):
Schaum, M., Duarte, J. V., Martins, R., Duarte, I. C., Castelhano, J., Wibral, M., Castelo-Branco, M.
Document type:
Article
Number of reproductions:
1
Reference:
Costa, G. N., Schaum, M., Duarte, J. V., Martins, R., Duarte, I. C., Castelhano, J., Wibral, M., & Castelo-Branco, M. (2024). Distinct oscillatory patterns differentiate between segregation and integration processes in perceptual grouping. Human Brain Mapping, 45(12), e26779. https://doi.org/10.1002/hbm.26779
2-year Impact Factor: 1.06|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2024-10-15
Indexed document: Yes
Quartile: Q1
Keywords: Alpha and beta rhythms / Gamma activity / Intracranial recordings / Magnetoencephalography (MEG) / Oscillations / Perceptual binding / StereoEEG

Distinct oscillatory patterns differentiate between segregation and integration processes in perceptual grouping

Distinct oscillatory patterns differentiate between segregation and integration processes in perceptual grouping