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DocumentNeuronal activation at the spinal cord and medullary pain control centers after joint stimulation: a c-fos study in acute and chronic articular inflammation2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-015
Location: Arquivo PCA - Pasta 21/2004
Title:
015 - Pain control from the brain - Gene therapy in the treatment of chronic pain
Duration: 2005-01 - 2009-01
Researcher(s):
Deolinda Lima, Isaura Ferreira Tavares, Marta Pinto, Isabel Martins
Institution(s): Instituto de Histologia e Embriologia, Faculdade de Medicina da Universidade do Porto (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 posters
Language: eng
Author:
Lima, D.
Secondary author(s):
Tavares, I., Pinto, M., Martins, I.
Number of reproductions:
1
Keywords:
Psychophysiology / Pain

Reference code: PT/FB/BL-2004-015.05
Location: Arquivo PCA - Pasta 21/2004
Title:
Neuronal activation at the spinal cord and medullary pain control centers after joint stimulation: a c-fos study in acute and chronic articular inflammation
Publication year: 2007
URL:
http://www.sciencedirect.com/science/article/pii/S0306452207006628
Abstract/Results: ABSTRACT:
Chronic inflammatory pain induces short- and long-term central changes, which have been mainly studied at the spinal cord level. Supraspinal pain control centers intrinsically connected with the dorsal horn are also prone to be affected by chronic inflammatory pain. C-fos expression was used as a neuronal activation marker at spinal and supraspinal levels to i) compare acute and chronic articular inflammation, and ii) analyze the effects of brief innocuous or noxious stimulation of a chronically inflamed joint. Acute articular inflammation was induced by an inflammatory soup with prostaglandin E(2) and bradykinin, both at 10-5 M. Chronic articular inflammation consisted of 14 days of monoarthritis. Early c-fos expression was studied 4 min after inflammatory soup injection or stimulation of the arthritic joint whereas late c-fos expression was evaluated 2 h after those stimuli. At the spinal cord, the analysis was focused on the dorsal horn (laminae I–V) and supraspinally, five major regions of the endogenous pain control system were considered: the caudal ventrolateral medulla (VLM), the dorsal reticular nucleus (DRt), the ventral reticular nucleus (VRt), the nucleus of the solitary tract (Sol) and the rostroventromedial medulla (RVM). Acute articular inflammation induced early and late increases in c-fos expression at the spinal level and late increases supraspinally whereas the effects of monoarthritis were more moderate and restricted to the spinal cord. When monoarthritic animals were subjected to gentle touch or bending of the joint, early increases in c-fos expression were detected supraspinally, but not at the spinal level. In this region, noxious mechanical stimulation induced late increases in non-inflamed animals and both early and late increases in monoarthritic rats. Supraspinally, noxious stimulation induced only late increases in c-fos expression. The present results show complex differences in the patterns of c-fos expression between the spinal cord and medullary areas of the pain control system during articular inflammation, which indicate that the somatosensory system is differentially affected by the installation of chronic pain.
Accessibility: Document does not exist in file
Language:
eng
Author:
Pinto, M.
Secondary author(s):
Lima, D., Tavares, I.
Document type:
Article
Number of reproductions:
1
Reference:
Pinto, M., Lima, D., & Tavares, I. (2007). Neuronal activation at the spinal cord and medullary pain control centers after joint stimulation: a c-fos study in acute and chronic articular inflammation. Neuroscience, 147(4), 1076-1089. doi: 10.1016/j.neuroscience.2007.05.019
2-year Impact Factor: 3.352|2007
Times cited: 25|2021-05-14
Indexed document: Yes
Quartile: Q2
Keywords: Supraspinal pain control areas / Central sensitization / Plasticity / Monoarthritis / Innocuous stimulation / Noxious stimulation

DocumentMeditators and non-meditators: EEG source imaging during resting2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-044
Location: Arquivo PCA - Pasta 19/2006
Title:
044 - Brain electric activity in meditation: Extension of earlier work and hypothesis testing
Duration: 2007-10 - 2010-01
Researcher(s):
Dietrich Lehmann, Shisei Tei, Pascal Faber, Hiraoki Kumano, Lorena Gianotti, Roberto Pascual-Marqui
Institution(s): The KEY Institute for Brain-Mind Research, University Hospital of Psychiatry, Zurich (Switzerland)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
8 Articles (published or submitted)
14 Posters
Language: eng
Author:
Lehmann, D.
Secondary author(s):
Tei, S., Faber, P., Kumano, H., Gianotti, L., Pascual-Marqui, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Altered states of consciousness / Meditation

Reference code: PT/FB/BL-2006-044.02
Location: Arquivo PCA - Pasta 19/2006
Title:
Meditators and non-meditators: EEG source imaging during resting
Publication year: 2009
URL:
http://link.springer.com/article/10.1007/s10548-009-0107-4
Abstract/Results: ABSTRACT:
Many meditation exercises aim at increased awareness of ongoing experiences through sustained attention and at detachment, i.e., non-engaging observation of these ongoing experiences by the intent not to analyze, judge or expect anything. Long-term meditation practice is believed to generalize the ability of increased awareness and greater detachment into everyday life. We hypothesized that neuroplasticity effects of meditation (correlates of increased awareness and detachment) would be detectable in a no-task resting state. EEG recorded during resting was compared between Qigong meditators and controls. Using LORETA (low resolution electromagnetic tomography) to compute the intracerebral source locations, differences in brain activations between groups were found in the inhibitory delta EEG frequency band. In the meditators, appraisal systems were inhibited, while brain areas involved in the detection and integration of internal and external sensory information showed increased activation. This suggests that neuroplasticity effects of long-term meditation practice, subjectively described as increased awareness and greater detachment, are carried over into non-meditating states.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Tei, S.
Secondary author(s):
Faber, P., Lehmann, D., Tsujiuchi, T., Kumano, H., Pascual-Marqui, R., Gianotti, L., Kochi, K.
Document type:
Article
Number of reproductions:
1
Reference:
Tei, S., Faber, P., Lehmann, D., Tsujiuchi, T., Kumano, H., Pascual-Marqui, R., Gianotti, L., & Kochi, K. (2009). Meditators and non-meditators: EEG source imaging during resting. Brain Topography, 22(3), 158-165. doi: 10.1007/s10548-009-0107-4
2-year Impact Factor: 2.080|2009
Times cited: 35|2021-05-18
Indexed document: Yes
Quartile: Q3
Keywords: Meditation / Qigong / LORETA / Plasticity / Electroencephalogram (EEG) localization

Meditators and non-meditators: EEG source imaging during resting

Meditators and non-meditators: EEG source imaging during resting

DocumentDeactivation of the medial prefrontal cortex in experienced Zen meditators2008

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-044
Location: Arquivo PCA - Pasta 19/2006
Title:
044 - Brain electric activity in meditation: Extension of earlier work and hypothesis testing
Duration: 2007-10 - 2010-01
Researcher(s):
Dietrich Lehmann, Shisei Tei, Pascal Faber, Hiraoki Kumano, Lorena Gianotti, Roberto Pascual-Marqui
Institution(s): The KEY Institute for Brain-Mind Research, University Hospital of Psychiatry, Zurich (Switzerland)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
8 Articles (published or submitted)
14 Posters
Language: eng
Author:
Lehmann, D.
Secondary author(s):
Tei, S., Faber, P., Kumano, H., Gianotti, L., Pascual-Marqui, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Altered states of consciousness / Meditation

Reference code: PT/FB/BL-2006-044.17
Location: Arquivo PCA - Pasta 19/2006
Title:
Deactivation of the medial prefrontal cortex in experienced Zen meditators
Publication year: 2008
Accessibility:
Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Faber, P.
Secondary author(s):
Steiner, M., Lehmann, D., Pascual-Marqui, R., Jäncke, L., Esslen, M., Gianotti, L.
Document type:
Abstract
Number of reproductions:
1
Reference:
Faber, P., Steiner, M., Lehmann, D., Pascual-Marqui, R., Jäncke, L., Esslen, M., & Gianotti, L. (2008). Deactivation of the medial prefrontal cortex in experienced Zen meditators. Brain Topography, 20(3), 172. doi: 10.1007/s10548-007-0042-1
Indexed document: Yes
Keywords: Zazen meditation / Brain activity / Resting / Plasticity

Deactivation of the medial prefrontal cortex in experienced Zen meditators

Deactivation of the medial prefrontal cortex in experienced Zen meditators

DocumentThe role of stress in cortico-basal ganglia loop processing and instrumental conditioning2010

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-134
Location: Arquivo PCA - Pasta 11/2006
Title:
134 - The role of stress in cortico-basal ganglia loop processing and instrumental conditioning
Duration: 2007-01 - 2010-02
Researcher(s):
Nuno Jorge Carvalho de Sousa, Rui Manuel Fernandes da Costa, Eduardo Miguel Gonçalves Dias Ferreira, João José Cerqueira, Pedro Alexandre Teixeira
Institution(s): Life and Health Sciences Research Unit, School of Health Sciences, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Sousa, N.
Secondary author(s):
Costa, R. M., Dias-Ferreira, E., Cerqueira, J., Teixeira, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Stress and health / Chronic stress / Brain structure and function / Cognitive processes / Decision-making

Reference code: PT/FB/BL-2006-134.07
Location: Arquivo PCA - Pasta 11/2006
Title:
The role of stress in cortico-basal ganglia loop processing and instrumental conditioning
Publication year: 2010
URL:
http://www.bial.com/simposio/Livro_de_Actas_8_Simposio.pdf
Abstract/Results: ABSTRACT:
The ability to shift between different behavioral strategies is necessary for appropriate decision-making. In this project, we investigated if chronic stress biases decision-making strategies, affecting the ability of stressed rats to perform actions based on their consequences. Using two different operant tasks, we uncovered that choices made by rats, and now confirmed for mice, submitted to chronic stress become insensitive to changes in outcome value and resistant to changes in action-outcome contingency. Furthermore, we demonstrated that chronic stress caused opposing structural changes in the associative and sensorimotor corticostriatal circuits underlying different behavioral strategies, with atrophy of medial prefrontal cortex (mPFC) and the associative striatum (dorsomedial striatum, DMS), and hypertrophy of the sensorimotor striatum (dorsolateral striatum, DLS). Therefore, we recorded the simultaneous activity of neuronal ensembles in mPFC, DMS and DLS of control and stressed mice during behavioral training and testing to investigate if the changes in wiring observed in the associative and sensorimotor circuits after chronic stress cause changes in neural activity in these circuits that could explain the bias in behavioral strategies towards habit. In conclusion, the results obtained throughout this project demonstrate that chronic stress influences decision-making processes, through changes in the structure and activity of corticostriatal networks.
Accessibility: Document does not exist in file
Language:
eng
Author:
Sousa, N.
Secondary author(s):
Costa, R. M., Dias-Ferreira, E., Cerqueira, J., Teixeira, P.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Sousa, N., Costa, R. M., Dias-Ferreira, E., Cerqueira, J., & Teixeira, P. (2010). The role of stress in cortico-basal ganglia loop processing and instrumental conditioning. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 8th Symposium of Fundação Bial (pp. 231-232). Porto: Fundação Bial.
Indexed document: No
Keywords: Corticosteroids / Decision-making / Plasticity / Striatum / Multielectrode recordings

The role of stress in cortico-basal ganglia loop processing and instrumental conditioning

The role of stress in cortico-basal ganglia loop processing and instrumental conditioning

DocumentThe different faces of one's self: An fMRI study into the recognition of current and past self-facial appearances2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-086
Location: Arquivo PCA - Pasta 4/2010
Title:
086 - The different faces of one's self: Neural correlates of changes in self-identity
Duration: 2011-09 - 2012-10
Researcher(s):
Ana Tajadura-Jiménez, Emmanouil (Manos) Tsakiris
Institution(s): Department of Psychology, Royal Holloway University of London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
1 Article
1 Poster
Language: eng
Author:
Tajadura-Jiménez, A.
Secondary author(s):
Tsakiris, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Self

Reference code: PT/FB/BL-2010-086.02
Location: Arquivo PCA - Pasta 4/2010
Title:
The different faces of one's self: An fMRI study into the recognition of current and past self-facial appearances
Publication year: 2012
URL:
http://www.sciencedirect.com/science/article/pii/S1053811912008610
Abstract/Results: ABSTRACT:
Mirror self-recognition is often considered as an index of self-awareness. Neuroimaging studies have identified a neural circuit specialised for the recognition of one's own current facial appearance. However, faces change considerably over a lifespan, highlighting the necessity for representations of one's face to continually be updated. We used fMRI to investigate the different neural circuits involved in the recognition of the childhood and current, adult, faces of one's self. Participants viewed images of either their own face as it currently looks morphed with the face of a familiar other or their childhood face morphed with the childhood face of the familiar other. Activity in areas which have a generalised selectivity for faces, including the inferior occipital gyrus, the superior parietal lobule and the inferior temporal gyrus, varied with the amount of current self in an image. Activity in areas involved in memory encoding and retrieval, including the hippocampus and the posterior cingulate gyrus, and areas involved in creating a sense of body ownership, including the temporo-parietal junction and the inferior parietal lobule, varied with the amount of childhood self in an image. We suggest that the recognition of one's own past or present face is underpinned by different cognitive processes in distinct neural circuits. Current self-recognition engages areas involved in perceptual face processing, whereas childhood self-recognition recruits networks involved in body ownership and memory processing.
Accessibility: Document exists in file (previous version submitted for publication)
Copyright/Reproduction:
By permission
Language:
eng
Author:
Apps, M. A.
Secondary author(s):
Tajadura-Jiménez, A., Turley, G., Tsakiris, M.
Document type:
Article
Number of reproductions:
1
Reference:
Apps, M. A., Tajadura-Jiménez, A., Turley, G., & Tsakiris, M. (2012). The different faces of one's self: An fMRI study into the recognition of current and past self-facial appearances. NeuroImage, 63(3), 1720-1729. doi: 10.1016/j.neuroimage.2012.08.053
2-year Impact Factor: 6.252|2012
Times cited: 25|2021-05-18
Indexed document: Yes
Quartile: Q1
Keywords: Self / Faces / Recognition / Functional magnetic resonance imaging (fMRI) / Ownership / Plasticity

The different faces of one's self: An fMRI study into the recognition of current and past self-facial appearances

The different faces of one's self: An fMRI study into the recognition of current and past self-facial appearances

DocumentHow does cognitive enrichment impact on neuronal networks and behavioral performance?2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-134
Location: Arquivo PCA - Pasta 22/2008
Title:
134 - How does cognitive enrichment impact on neuronal networks and behavioral performance?
Duration: 2010-05 - 2014-11
Researcher(s):
João José Cerqueira, Igor L. M. Spínola, Irene Melo Carvalho, Pedro Ricardo Luís Morgado, Ricardo Jorge Moreira Taipa
Institution(s): Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Article
Language: eng
Author:
Cerqueira, J.
Secondary author(s):
Spínola, I., Carvalho, I., Morgado, P., Taipa, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Brain structure and function / Stress and health / Chronic stress / Intervention

Reference code: PT/FB/BL-2008-134.03
Location: Arquivo PCA - Pasta 22/2008
Title:
How does cognitive enrichment impact on neuronal networks and behavioral performance?
Publication year: 2012
URL:
http://www.bial.com/imagem/Bial%20Sonhos%20Miolo_Total%20Bolsas.pdf
Abstract/Results: ABSTRACT:
Introduction: Several studies in animal models have demonstrated that chronic stress exposure
induces alterations in the structure and function of the hippocampal formation and medial
prefrontal (mPFC). Also relevant, was the finding that such functional and structural changes
partially reverted following cessation of stress exposure; importantly, functional recovery was
correlated with synaptogenesis and dendritic plasticity, at least in the hippocampus.
Objective: The present study aimed to assess the ability of cognitive stimulation to abrogate the
negative effects of chronic stress exposure on learning and memory performances.
Methods: As it is conceivable that specific cognitive stimulation differently enhance brain circuits,
rats free of stress-exposure (CON) and animals previously submitted to chronic unpredictable
stress (CUS) were submitted to spatial reference memory stimulus using the hole board (RM)
paradigm (CON+RM and CUS+RM) while others were trained in a T-maze (WM), a working memory
tasks (CON+WM and CUS+WM).
Results: Behavioral data confirms that stress impairs both reference and working memory.
Importantly, these behavioural underperformances were reverted with cognitive tasks.
Interestingly, however, each individual task ameliorates predominantly that specific cognitive
behaviour, which reinforces the view that neuronal plasticity is circuit-dependent. Structural
analysis of animals submitted chronic stress reveals a trend to recovery of neuropil changes in the
hippocampal formation, but not in the mPFC, after reference memory stimulation (CUS+RM).
Conversely, after working memory stimulation there’s a trend towards recovery of neuropil
changes in the mPFC but not in the hippocampus.
Conclusion and discussion: In conclusion, these preliminary results suggest that reinforcement of
specific cognitive circuits (“cognitive-enrichment”) triggers synaptic plasticity mainly within the
brain circuits implicated in that particular task. These basic experimental procedures provide an
insight on the ability to recover from stress-induced impairments in animal models, which might
prove relevant in the pathogenesis and recovery of several neurological and psychiatric disorders.
Accessibility: Document does not exist in file
Language:
eng
Author:
Cerqueira, J.
Secondary author(s):
Spínola, I., Carvalho, I., Morgado, P., Taipa, R.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Cerqueira, J., Spínola, I., Carvalho, I., Morgado, P. & Taipa, R. (2012). How does cognitive enrichment impact on neuronal networks and behavioral performance? In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 9th Symposium of Fundação Bial (p. 43/63). Porto: Fundação Bial.
Indexed document: No
Keywords: Chronic stress / Plasticity / Long-term potentiation

Novo ficheiro

Novo ficheiro

DocumentWhat can mice tell us about Foxp2 function?2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-192
Location: Arquivo PCA - Pasta 15/2012
Title:
192 - Effects of conditional Foxp2 deletion on motor-sequence learning
Duration: 2013-06 - 2016-07
Researcher(s):
Catherine Ann French
Institution(s): Fundação Champalimaud, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 articles (published and submitted)
Language: eng
Author:
French, C.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Chromosomal abnormalities / Brain structure and function / Cognitive processes / Learning / Body structure and function / Movement

Reference code: PT/FB/BL-2012-192.03
Location: Arquivo PCA - Pasta 15/2012
Title:
What can mice tell us about Foxp2 function?
Publication year: 2014
URL:
http://www.sciencedirect.com/science/article/pii/S0959438814001299
Abstract/Results: ABSTRACT:
Disruptions of the FOXP2 gene cause a rare speech and language disorder, a discovery that has opened up novel avenues for investigating the relevant neural pathways. FOXP2 shows remarkably high conservation of sequence and neural expression in diverse vertebrates, suggesting that studies in other species are useful in elucidating its functions. Here we describe how investigations of mice that carry disruptions of Foxp2 provide insights at multiple levels: molecules, cells, circuits and behaviour. Work thus far has implicated the gene in key processes including neurite outgrowth, synaptic plasticity, sensorimotor integration and motor-skill learning.
Accessibility: Document does not exist in file
Language:
eng
Author:
French, C. A.
Secondary author(s):
Fisher, S. E.
Document type:
Article
Number of reproductions:
1
Reference:
French, C. A., & Fisher, S. E. (2014). What can mice tell us about Foxp2 function? Current Opinion in Neurobiology, 28, 72–79. doi: 10.1016/j.conb.2014.07.003
2-year Impact Factor: 6.628|2014
Times cited: 43|2021-05-19
Indexed document: Yes
Quartile: Q1
Keywords: Foxp2 / Speech and language / Motor learning / Plasticity

File347 - Driving synaptic plasticity in motor-to-visual neural pathways to enhance action prediction

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-347
Location: BF-GMS
Title:
347 - Driving synaptic plasticity in motor-to-visual neural pathways to enhance action prediction
Researcher(s): Alessio Avenanti, Emmanuele Tidoni, Marco Zanon
Institution(s): Department of Psychology, Alma Mater Studiorum - Università di Bologna (Italy)
Contents: Contents:
Application form
Correspondence
Language: eng
Notes:
This project hasn't started yet
Author: Avenanti, A.
Secondary author(s):
Tidoni, E., Zanon, M.
Number of reproductions:
1
Keywords:
Action observation / Prediction / Plasticity / Connectivity / Psychophysiology

DocumentAge-related changes in cortical connectivity influence the neuromodulatory effects of transcranial electrical stimulation2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-277
Location: BF-GMS
Title:
277 - Cortical excitability and connectivity in the lifespan: a neurophysiological study
Duration: 2015-09 - 2019-06
Researcher(s):
Anna Fertonani, Cornelia Pirulli
Institution(s): IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Fertonani, A.
Secondary author(s):
Pirulli, C., Bollini, A.
Number of reproductions:
1
Keywords:
Aging / Neuroplasticity / Brain stimulation techniques / TMS-EEG / Psychophysiology

Reference code: PT/FB/BL-2014-277.03
Location: BF-GMS
Title:
Age-related changes in cortical connectivity influence the neuromodulatory effects of transcranial electrical stimulation
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0197458019302118
Abstract/Results: ABSTRACT:
Transcranial electrical stimulation (tES) is a potentially viable tool for boosting cognitive performance in aging. However, most knowledge on tES effects is based on studies involving young adults. Here, we applied tES (transcranial random noise stimulation [tRNS] as an effective stimulation and anodal transcranial direct current stimulation [atDCS] as a “control” stimulation) to the visual cortex during visual perceptual learning (VPL) in healthy young and older individuals. Moreover, we measured transcranial magnetic stimulation–evoked potentials to investigate the neurophysiological underpinnings of tES effects. We found that only the tRNS in the young, but not in the older, subjects modulated VPL, by decreasing performance. Transcranial magnetic stimulation–evoked potentials revealed age-related changes in connectivity, that is, a stronger activation of the prefrontal cortex after visual cortex stimulation, and a stronger modulation of the prefrontal cortex after VPL in the older subjects. These results may indicate that task performance in older adults relies on the recruitment of a wider network and a crucial contribution of the anterior portion of the brain, which may dramatically influence tES effects in aging.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Fertonani, A.
Secondary author(s):
Pirulli, C., Bollini, A., Miniussi, C., Bortoletto, M.
Document type:
Article
Number of reproductions:
1
Reference:
Fertonani, A., Pirulli, C., Bollini, A., Miniussi, C., & Bortoletto, M. (2019). Age-related changes in cortical connectivity influence the neuromodulatory effects of transcranial electrical stimulation. Neurobiology of Aging, 82, 77-87. doi: 10.1016/j.neurobiolaging.2019.07.009
2-year Impact Factor: 4.347|2019
Impact factor notes: Impact factor not available yet for 2019
Times cited: 1|2021-05-21
Indexed document: Yes
Quartile: Q1
Keywords: Learning / TMS-EEG / Visual cortex / Connectivity / Plasticity / Noninvasive brain stimulation

DocumentFinal report - Maternal Brain Gain: Changes in neural representations and body perception during pregnancy2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-121
Location: BF-GMS
Title:
121 - Maternal Brain Gain: Changes in neural representations and body perception during pregnancy
Duration: 2015-11 - 2019-06
Researcher(s):
Jane Aspell, Flavia Cardini
Institution(s): Anglia Ruskin University, Cambridge (UK)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Aspell, J. E.
Secondary author(s):
Cardini, F.
Number of reproductions:
1
Keywords:
Pregnancy / Peripersonal space / Interoception / Tactile perception / Psychophysiology

Reference code: PT/FB/BL-2014-121.03
Location: BF-GMS
Title:
Final report - Maternal Brain Gain: Changes in neural representations and body perception during pregnancy
Publication year: 2019
Abstract/Results:
ABSTRACT
BACKGROUND
The space immediately surrounding our body – i.e. ‘peripersonal space’ (PPS; Rizzolatti et al., 1997) - is important, as it is where we interact with stimuli in the external world. Recent studies have shown that the PPS boundaries are malleable. For example, it has been found that being in proximity to an individual we have previously co-operated with induces an expansion of our PPS towards that person.
AIMS
With our study we aimed at investigating whether the PPS changes during pregnancy, a critical stage in life, when extremely rapid changes occur in the body size and shape. As pregnancy advances, the PPS should expand, reflecting an updated mental representation of one’s body that makes external stimuli, initially perceived as being outside of the PPS, to be perceived closer, within the PPS.
METHODS
To this aim, we tested 37 pregnant women and 19 non-pregnant women three times: at the 20th and at 34th week of the gestational period and 8 weeks postpartum (and at the same time intervals in the control group). To assess the PPS boundaries we used a well-established audiotactile task (Canzoneri et al., 2012) whereby participants’ reaction times (RTs) to a tactile stimulus on the abdomen, were measured while listening to a dynamic sound that seems to start at a location far from the participant and progressively approach the participant’s body. When touches occurred at short temporal delays the sound was perceived far and gradually closer to the participant’s body as the delays increase. As sounds facilitate tactile RTs only when presented close to the body (Serino et al., 2007), we expected RTs to progressively decrease as the sound was approaching. The critical distance where the sound speeds up tactile RTs can be taken as a proxy of the PPS boundary.
RESULTS
By comparing this critical distance across the three time periods we found that whereas at the first and the third testing period no differences in the PPS size were observed between the groups, in the second period, the pregnant participants’ PPS was larger than the controls’.
CONCLUSIONS
We conclude that during pregnancy our brain adapts to the sudden change in body size, by expanding the representation of the space around us, possibly in order to protect the vulnerable abdomen from bumping against objects.
Accessibility: Document exists in file
Language:
eng
Author:
Aspell, J. E.
Secondary author(s):
Cardini, F.
Document type:
Final report
Number of reproductions:
1
Reference:
Aspell, J. E., & Cardini, F. (2019). Final report - Maternal Brain Gain: Changes in neural representations and body perception during pregnancy.
Indexed document: No
Keywords: Pregnancy / Plasticity / Interoception / Exteroception / Peripersonal Space

Final report - Maternal Brain Gain: Changes in neural representations and body perception during pregnancy

Final report - Maternal Brain Gain: Changes in neural representations and body perception during pregnancy

DocumentBrain mechanisms of insomnia: new perspectives on causes and consequences2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-190
Location: BF-GMS
Title:
190 - Sleeping body, sentient mind? Searching for the neural bases of conscious experiences during sleep
Duration: 2017-10 - 2019-06
Researcher(s):
Eus Van Someren, Yishul Wei
Institution(s): Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Article
Author: Van Someren, E.
Secondary author(s):
Wei, Y.
Number of reproductions:
1
Keywords:
Interoception / Insomnia / Neural correlates of consciousness / Salience / Psychophysiology

Reference code: PT/FB/BL-2016-190.07
Location: BF-GMS
Title:
Brain mechanisms of insomnia: new perspectives on causes and consequences
Publication year: 2020
URL:
https://journals.physiology.org/doi/pdf/10.1152/physrev.00046.2019
Abstract/Results: ABSTRACT:
While insomnia is the second most common mental disorder, progress in our understanding of underlying neurobiological mechanisms has been limited. The present review addresses the definition and prevalence of insomnia and explores its subjective and objective characteristics across the 24-hour day. Subsequently, the review extensively addresses how the vulnerability to develop insomnia is affected by gene variants, early life stress and major life events and brain structure and function. Further supported by the clear mental health risks conveyed by insomnia, the integrated findings suggest that the vulnerability to develop insomnia could rather be found in brain circuits regulating emotion and arousal than in circuits involved in circadian and homeostatic sleep regulation. Finally, a testable model is presented. The model proposes that in people with a vulnerability to develop insomnia, the locus coeruleus is more sensitive to - or receives more input from - the salience network and related circuits, even during REM sleep, when it should normally be sound asleep. This vulnerability may ignite a downwards spiral of insufficient overnight adaptation to distress, resulting in accumulating hyperarousal which in turn impedes restful sleep and moreover increases the risk of other mental health adversity. Sensitized brain circuits are likely to be subjectively experienced as "sleeping with one eye open". The proposed model opens up the possibility for novel intervention studies and animal studies, thus accelerating the ignition of a neuroscience of insomnia, which is direly needed for better treatment.
Accessibility: Document does not exist in file
Language:
eng
Author:
Van Someren, E. J. W.
Document type:
Article
Number of reproductions:
1
Reference:
Van Someren, E. J. W. (2020). Brain mechanisms of insomnia: New perspectives on causes and consequences. Physiological Reviews. doi: 10.1152/physrev.00046.2019
2-year Impact Factor: 37.312|2020
Times cited: 6|2021-08-24
Indexed document: Yes
Quartile: Q1
Keywords: Insomnia / Plasticity / Locus coeruleus / Anxiety / Depression