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Document

Focal basal ganglia damage and procedural memory

2004

BIAL Foundation Archive
- BIAL Grants
  - 2002 Grants
    - 003 - The neural structures involved in procedural memory
      - Focal basal ganglia damage and procedural memory

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2002
Location:	Arquivo PCA - Pastas 1 a 21/2002
Title:	2002 Grants
Start date:	2003-01 - 2009-11
Dimension/support:	21 caixas de arquivo

Reference code:	PT/FB/BL-2002-003
Location:	Arquivo PCA - Pasta 8/2002
Title:	003 - The neural structures involved in procedural memory
Duration:	2003-11 - 2006-11
Researcher(s):	Sara Cavaco, Alexandre Lemos de Castro Caldas, Steven Anderson
Institution(s):	Centro de Estudos Egas Moniz, Lisboa (Portugal)
Contents:	Contents: Application form Correspondence Financial report and expenditure documents Progress reports Final report
Language:	eng
Author:	Cavaco, S.
Secondary author(s):	Castro-Caldas, A., Anderson, S.
Number of reproductions:	1
Keywords:	Psychophysiology / Biopsychological problems / Diseases/Injuries / Brain dysfunction / Cognitive processes / Learning

Reference code:	PT/FB/BL-2002-003.02
Location:	Arquivo PCA - Pasta 8/2002
Title:	Focal basal ganglia damage and procedural memory
Publication year:	2004
URL:	http://journals.cambridge.org/download.php?file=%2FINS%2FINS10_S2%2FS1355617704040032a.pdf&code=d2229a98a90450fba8274c4fdfabca59
Abstract/Results:	ABSTRACT: There is evidence that damage to the basal ganglia impairs acquisition of perceptual-motor skills. The data have come primarily from studies of patients with neurodegenerative diseases (Parkinson’s and Huntington’s Disease), and have relied on a limited number of laboratory tasks (i.e., Serial Reaction Time Test, Rotor Pursuit, Mirror Tracing). The goal of this study was to further explore the impairments of procedural memory that result from basal ganglia dysfunction, by examining the performances of subjects with focal lesions in this region on a new set of procedural memory tasks. The performances of 8 subjects with unilateral basal ganglia vascular lesions (2 left; 6 right) were compared to 25 normal control subjects on 5 new laboratory-controlled tasks based on real world activities, encompassing a range of perceptual-motor requirements. The tasks were administered in two time periods (Time 1 and Time 2 - 24 hours). The 1st task consisted of pressing a sequence of 5 buttons without visual guidance. The 2nd task consisted of manually tracking constant series of 8 target locations using a joystick. The 3rd task consisted of weaving fabric with an actual loom, by performing a recurrent 5-step routine. The 4th consisted of tracing moving geometric figures with a stylus on a touch screen monitor. The 5th consisted of pouring water from a small watering can into graduated containers, from a point at 20cm distance. The basal ganglia group showed a trend toward reduced acquisition and/or retention on 4 of the 5 tasks (all except the 2nd task), relative to the control group, but the differences between groups were statistically nonsignificant. Each basal ganglia subject showed impaired acquisition and/or retention on at least one of the tasks. The findings provide further evidence for impairment of perceptual-motor skill learning and retention following basal ganglia damage, and suggest that lesion and patient characteristics may influence expression of the impairment.
Accessibility:	Document does not exist in file
Language:	eng
Author:	Cavaco, S.
Secondary author(s):	Castro-Caldas, A.
Document type:	Abstract
Number of reproductions:	1
Reference:	Cavaco, S., Anderson, S., Castro-Caldas, A., & Damásio, H. (2004). Focal basal ganglia damage and procedural memory. Journal of the International Neuropsychological Society, 10(4), 5.
Indexed document:	Yes
Keywords:	Psychophysiology / Procedural memory / Basal ganglia dysfunction / Perceptual-motor skill learning

Document

The neural structures involved in procedural memory

2008

BIAL Foundation Archive
- BIAL Grants
  - 2002 Grants
    - 003 - The neural structures involved in procedural memory
      - The neural structures involved in procedural memory

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2002
Location:	Arquivo PCA - Pastas 1 a 21/2002
Title:	2002 Grants
Start date:	2003-01 - 2009-11
Dimension/support:	21 caixas de arquivo

Reference code:	PT/FB/BL-2002-003
Location:	Arquivo PCA - Pasta 8/2002
Title:	003 - The neural structures involved in procedural memory
Duration:	2003-11 - 2006-11
Researcher(s):	Sara Cavaco, Alexandre Lemos de Castro Caldas, Steven Anderson
Institution(s):	Centro de Estudos Egas Moniz, Lisboa (Portugal)
Contents:	Contents: Application form Correspondence Financial report and expenditure documents Progress reports Final report
Language:	eng
Author:	Cavaco, S.
Secondary author(s):	Castro-Caldas, A., Anderson, S.
Number of reproductions:	1
Keywords:	Psychophysiology / Biopsychological problems / Diseases/Injuries / Brain dysfunction / Cognitive processes / Learning

Reference code:	PT/FB/BL-2002-003.09
Location:	Arquivo PCA - Pasta 8/2002
Title:	The neural structures involved in procedural memory
Publication year:	2008
URL:	http://www.bial.com/imagem/Actas_7Simp.pdf
Accessibility:	Document does not exist in file
Language:	eng
Author:	Cavaco, S.
Secondary author(s):	Castro-Caldas, A., Anderson, A.
Document type:	Conference abstract
Number of reproductions:	1
Reference:	Cavaco, S., Castro-Caldas, A., & Anderson, A. (2008). The neural structures involved in procedural memory. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 7th Symposium of Fundação Bial. Porto: Fundação Bial.
Indexed document:	No
Keywords:	Procedural memory / Skill learning / Striatum
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