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DocumentAn encounter with the self: A thematic and content analysis of DMT experiences from a naturalistic field study2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-359
Location: BF-GMS
Title:
359 - A comparison of NN-DMT, Changa & 5-MeO-DMT and the Near-death Experience: Qualitative analyses and reviews of the neuroscience
Duration: 2020/01 - 2024/05
Researcher(s):
Pascal Michael, David Luke
Institution(s): Department of Psychology, Social Work and Counselling, Greenwich University, London (UK); Psychedelic Research Group, Imperial College London (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Michael, P.
Secondary author(s):
Luke, D.
Number of reproductions:
3
Keywords:
Near-death experience / Dimethyltryptamine/DMT / Phenomenology / Pineal Gland / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2018-359.02
Location: BF-GMS
Title:
An encounter with the self: A thematic and content analysis of DMT experiences from a naturalistic field study
Publication year: 2023
URL:
https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1083356/full
Abstract/Results: ABSTRACT:
Introduction:
N,N-Dimethyltryptamine (DMT) is an endogenous serotonergic psychedelic capable of producing radical shifts in an experience that have significant implications for consciousness and its neural correlates, especially given the "disconnected consciousness" suggested by the "breakthrough" DMT state. Its increasing usage and clinical trial indicate the growing importance of a thorough elucidation of the experience's qualitative content, over and above the phenomenological structure. This is particularly in light of the intensely pervasive effects of DMT occasions in all dimensions of the self, which are often ontologically challenging yet potentially transformative.
Methods:
This is the second report on the first naturalistic field study of DMT use exploring its qualitative analysis. Screened, healthy, anonymized, and experienced DMT users were observed during their non-clinical use of the drug at home (40-75-mg inhaled). In-depth semi-structured interviews, inspired by the micro-phenomenological technique, were employed immediately after their experience. This study reports on the thematic and content analysis of one major domain of the breakthrough experiences elicited, the "self"; where analyses of the "other" were previously reported. A total of 36 post-DMT experience interviews with mostly Caucasian (83%) men (eight women) of a mean of 37 years were predominantly inductively coded.
Results:
Invariably, profound and highly intense experiences occurred. The first overarching category comprised the onset of effects, encompassing super-ordinate themes including sensory, emotion and body, and space-time shifts; the second category comprised bodily effects, encompassing themes including pleasurable, neutral/both, and uncomfortable; the third category comprised the sensorial effects, encompassing open-eye, visual, and cross-modal and other; the fourth comprised the psychological effects, encompassing memory and language, awareness and sense of self, and time distortions; and the fifth comprised the emotional effects, encompassing positive, neither/both, and challenging experiences. Many further subthemes also illuminate the rich content of the DMT experience.
Discussion:
The present study provides a systematic and nuanced analysis of the content of the breakthrough DMT state pertaining to one's personal and self-referential experiences of the body, senses, psychology, and emotions. The resonances both with previous DMT studies and other types of extraordinary experiences, such as the alien abduction, shamanic and near-death experiences, are also elaborated upon. Putative neural mechanisms and their promise as a psychotherapeutic agent, especially owing to deep emotional impact, are discussed.
Accessibility: Document exists in file
Language:
eng
Author:
Michael, P.
Secondary author(s):
Luke, D., Robinson, O.
Document type:
Article
Number of reproductions:
3
Reference:
Michael, P., Luke, D., & Robinson, O. (2023). An encounter with the self: A thematic and content analysis of the DMT experience from a naturalistic field study. Frontiers in Psychology, 14, 1083356. https://doi.org/10.3389/fpsyg.2023.1083356
2-year Impact Factor: 2.6|2023
Times cited: 7|2025-09-26
Indexed document: Yes
Quartile: Q1
Keywords: Dimethyltryptamine / Thematic analysis / Naturalistic / Field study / Social / Psychedelic

An encounter with the other: A thematic and content analysis of DMT experiences from a naturalistic field study

An encounter with the other: A thematic and content analysis of DMT experiences from a naturalistic field study
DocumentAn encounter with the other: A thematic and content analysis of DMT experiences from a naturalistic field study2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-359
Location: BF-GMS
Title:
359 - A comparison of NN-DMT, Changa & 5-MeO-DMT and the Near-death Experience: Qualitative analyses and reviews of the neuroscience
Duration: 2020/01 - 2024/05
Researcher(s):
Pascal Michael, David Luke
Institution(s): Department of Psychology, Social Work and Counselling, Greenwich University, London (UK); Psychedelic Research Group, Imperial College London (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Michael, P.
Secondary author(s):
Luke, D.
Number of reproductions:
3
Keywords:
Near-death experience / Dimethyltryptamine/DMT / Phenomenology / Pineal Gland / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2018-359.03
Location: BF-GMS
Title:
An encounter with the other: A thematic and content analysis of DMT experiences from a naturalistic field study
Publication year: 2021
URL:
https://www.frontiersin.org/articles/10.3389/fpsyg.2021.720717/full
Abstract/Results: ABSTRACT:
Introduction: N,N-dimethyltryptamine (DMT) is an endogenous serotonergic psychedelic capable of producing radical shifts in conscious experience. Increasing trends in its use, as well as new trials administering DMT to patients, indicate the growing importance of a thorough elucidation of the qualitative content, over and above structure, which the drug occasions. This is particularly in light of the hyper-real, otherworldly, and often ontologically challenging yet potentially transformative, nature of the experience, not least encounters with apparently non-self social agents. Laboratory studies have been limited by clinical setting and lacking qualitative analyses of experiential content, while online surveys’ limitations lie in retrospective design, uncontrolled use, and both of which not guaranteeing ‘breakthrough’ experiences, i.e., producing very strong psychoactive effects.
Methods: We report on the first naturalistic field study of DMT use including its qualitative analysis. Screened, healthy, anonymised and experienced DMT users were observed during their non-clinical use of the drug at home (40–75 mg inhaled). In-depth semi-structured interviews (inspired by the micro-phenomenological technique) were employed immediately after their experience. This paper reports on the thematic analysis of one major domain of the breakthrough experiences elicited, the ‘other’. Thirty-six post-DMT experience interviews with mostly Caucasian (83%) males (eight female) of average 37 years were predominantly inductively coded.
Results: Invariably, profound and highly intense experiences occurred. The first overarching category comprised the encounter with other ‘beings’ (94% of reports), encompassing super-ordinate themes including the entities’ role, appearance, demeanour, communication and interaction; while the second overarching category comprised experiences of emerging into other ‘worlds’ (100% of reports), encompassing super-ordinate themes of the scene, the contents and quality of the immersive spaces. Many further mid-level themes and subthemes also illuminate the rich content of the DMT experience.
Discussion: The present study provides a systematic and in-depth analysis of the nuanced content of the otherworldly encounter within the breakthrough DMT experience, as well as elaborating on the resonances both with previous DMT studies focusing on entity encounters and other types of extraordinary experiences entailing such encounters. These include the alien abduction, folkloric, shamanic and near-death experience. Putative neural mechanisms of these features of the DMT experience and its promise as a psychotherapeutic agent are discussed in light of such findings.
Accessibility: Document exists in file
Language:
eng
Author:
Michael, P.
Secondary author(s):
Luke, D., Robinson, O.
Document type:
Article
Number of reproductions:
3
Reference:
Michael, P., Luke, D., & Robinson, O. (2021). An encounter with the other: A thematic and content analysis of DMT experiences from a naturalistic field study. Frontiers in Psychology, 12:720717. https://doi.org/10.3389/fpsyg.2021.720717
2-year Impact Factor: 4.232|2021
Times cited: 23|2025-09-20
Indexed document: Yes
Quartile: Q1
Keywords: Dimethyltryptamine / Thematic analysis / Naturalistic / Field study / Social / Psychedelic

An encounter with the other: A thematic and content analysis of DMT experiences from a naturalistic field study

An encounter with the other: A thematic and content analysis of DMT experiences from a naturalistic field study
DocumentBridging the gap: (a)typical psychedelic and near-death experience insights2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-065
Location: BF-GMS
Title:
065 - Unintended returns of awareness during cardiopulmonary resuscitation
Duration: 2023-02
Researcher(s):
Charlotte Martial, Pauline Fritz, Alice Clerget
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Articles
Language: eng
Notes:
Ongoing project
Author: Martial, C.
Secondary author(s):
Fritz, P., Clerget, A.
Number of reproductions:
3
Keywords:
Disconnected consciousness / Connected consciousness / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2022-065.03
Location: BF-GMS
Title:
Bridging the gap: (a)typical psychedelic and near-death experience insights
Publication year: 2024
URL:
https://doi.org/10.1016/j.cobeha.2023.101349
Abstract/Results: ABSTRACT:
Mystical-like states of consciousness may arise in different contexts, two of the most well-known being drug-induced psychedelic experiences and near-death experiences, which arise in potentially life-threatening contexts. We suggest and review emerging evidence that the former may model the latter in laboratory settings. This suggestion is based on their phenomenologically striking similarities. In addition, this paper highlights crucial directions and relevant questions that require future research in the field, including the challenges associated with their study in laboratory settings and their neurophysiological underpinnings.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Fritz, P.
Secondary author(s):
Lejeune, N., Cardone, P., Gosseries, O., Martial, C.
Document type:
Article
Number of reproductions:
3
Reference:
Fritz, P., Lejeune, N., Cardone, P., Gosseries, O., & Martial, C. (2024). Bridging the gap: (a)typical psychedelic and near-death experience insights. Current Opinion in Behavioral Sciences, 55, 101349. https://doi.org/10.1016/j.cobeha.2023.101349
2-year Impact Factor: 3.5|2024
Times cited: 7|2025-09-26
Indexed document: Yes
Quartile: Q1
Keywords: Near-death experience / Psychedelic / Phenomenology / Model
DocumentFinal report - A comparison of NN-DMT, Changa & 5-MeO-DMT and the Near-death Experience: Qualitative analyses and reviews of the neuroscience2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-359
Location: BF-GMS
Title:
359 - A comparison of NN-DMT, Changa & 5-MeO-DMT and the Near-death Experience: Qualitative analyses and reviews of the neuroscience
Duration: 2020/01 - 2024/05
Researcher(s):
Pascal Michael, David Luke
Institution(s): Department of Psychology, Social Work and Counselling, Greenwich University, London (UK); Psychedelic Research Group, Imperial College London (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Michael, P.
Secondary author(s):
Luke, D.
Number of reproductions:
3
Keywords:
Near-death experience / Dimethyltryptamine/DMT / Phenomenology / Pineal Gland / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2018-359.01
Location: BF-GMS
Title:
Final report - A comparison of NN-DMT, Changa & 5-MeO-DMT and the Near-death Experience: Qualitative analyses and reviews of the neuroscience
Publication year: 2024
Abstract/Results:
Abstract:
Background: The near-death experience (NDE) remains incompletely understood, but the parallels between psychedelic effects and NDE suggest a potential role for psychedelics in consciousness recovery. Psychometric and semantic analyses suggest psychedelics mimic NDEs. However, no dedicated comparative studies have explored qualitative differences, especially in participants experiencing both.
Methods: This thesis aimed to elucidate N,N-DMT experiences through thematic analysis of interviews conducted during a field study of DMT. Comparative analyses between this and classical NDEs were achieved, via near-death experience scale (NDES) administration, and comparing the DMT results with a re-analysis of a previously published thematic analyses of NDEs. NDE comparisons were also made in a within-subjects way, including a case study of 5-MeO-DMT and NDE, and two case studies of changa and NDE.
Results: DMT participants reported breakthrough experiences meeting entities with pervasive transformations. While some similarities to NDEs were found, notable differences in qualitative content were observed. 5-MeO-DMT showed partial replication of NDE mystical dimensions. Changa reports displayed moderate similarity to personal NDEs but higher similarity to NDEs in general.
Discussion and Conclusions: Each drug state mimics some NDE features but fails to replicate identical content. Therapeutic applications and neural correlates were discussed, along with the neurobiological and parapsychological aspects. Suggestions for future research include qualitative investigations into long-term consequences of these states.
Accessibility: Document exists in file
Language:
eng
Author:
Michael, P.
Document type:
Final report
Number of reproductions:
3
Reference:
Michael, P. (2024). Final report - A comparison of NN-DMT, Changa & 5-MeO-DMT and the Near-death Experience: Qualitative analyses and reviews of the neuroscience.
Indexed document: No
Keywords: Near-death experience / Psychedelic / DMT / Qualitative analysis / Neuroscience

Final report - A comparison of NN-DMT, Changa & 5-MeO-DMT and the near-death experience: Qualitative analyses and reviews of the neuroscience

Final report - A comparison of NN-DMT, Changa & 5-MeO-DMT and the near-death experience: Qualitative analyses and reviews of the neuroscience
DocumentMeditating on psychedelics. A randomized placebo-controlled study of DMT and harmine in a mindfulness retreat2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-333
Location: BF-GMS
Title:
333 - Mindfulness and psychedelics: A neurophenomenological approach to the characterization of acute and sustained response to DMT in experienced meditators
Duration: 2021-10 - 2024-05
Researcher(s):
Milan Scheidegger, Daniel Meling, Michael Kometer, Dario Dornbierer
Institution(s): Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich (Switzerland); University Medical Center Freiburg (Germany)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Articles
Final report
Language: eng
Author:
Scheidegger, M.
Secondary author(s):
Meling, D., Kometer, M., Dornbierer, D.
Number of reproductions:
3
Keywords:
Meditation / Psychedelics / Neurophenomenology / Brain imaging / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2020-333.07
Location: BF-GMS
Title:
Meditating on psychedelics. A randomized placebo-controlled study of DMT and harmine in a mindfulness retreat
Publication year: 2024
URL:
https://doi.org/10.1177/02698811241282637
Abstract/Results: ABSTRACT:
Background: In recent years, both meditation and psychedelics have attracted rapidly increasing scientific interest. While the current state of evidence suggests the promising potential of psychedelics, such as psilocybin, to enhance meditative training, it remains equivocal whether these effects are specifically bound to psilocybin or if other classical psychedelics might show synergistic effects with meditation practice. One particularly promising candidate is N,N-dimethyltryptamine (DMT), an active ingredient of ayahuasca.Aim: This study aims to investigate the effect of the psychedelic substance DMT, combined with the monoamine oxidase inhibitor harmine (DMT-harmine), on meditative states, compared to meditation with a placebo.Method: Forty experienced meditators (18 females and 22 males) participated in a double-blind, placebo-controlled study over a 3-day meditation retreat, receiving either placebo or DMT-harmine. Participants' levels of mindfulness, compassion, insight, and transcendence were assessed before, during, and after the meditation group retreat, using psychometric questionnaires.Results: Compared to meditation with a placebo, meditators who received DMT and harmine self-attributed greater levels of mystical-type experiences, non-dual awareness, and emotional breakthrough during the acute substance effects and, when corrected for baseline differences, greater psychological insight 1 day later. Mindfulness and compassion were not significantly different in the DMT-harmine group compared to placebo. At 1-month follow-up, the meditators who received DMT and harmine rated their experience as significantly more personally meaningful, spiritually significant, and well-being-enhancing than the meditators who received placebo.Conclusion: Investigating the impact of DMT-harmine on meditators in a naturalistic mindfulness group retreat, this placebo-controlled study highlights the specific effects of psychedelics during meditation. Trial registration: ClinicalTrials.gov identifier NCT05780216.
Accessibility: Document exists in file
Language:
eng
Author:
Meling, D.
Secondary author(s):
Egger, K., Aicher, H. D., Jareño Redondo, J., Mueller, J., Dornbierer, J., Temperli, E., Vasella, E. A., Caflisch, L., Pfeiffer, D. J., Schlomberg, J. T., Smallridge, J. W., Dornbierer, D. A., Scheidegger, M.
Document type:
Article
Number of reproductions:
3
Reference:
Meling, D., Egger, K., Aicher, H. D., Jareño Redondo, J., Mueller, J., Dornbierer, J., Temperli, E., Vasella, E. A., Caflisch, L., Pfeiffer, D. J., Schlomberg, J. T., Smallridge, J. W., Dornbierer, D. A., & Scheidegger, M. (2024). Meditating on psychedelics. A randomized placebo-controlled study of DMT and harmine in a mindfulness retreat. Journal of Psychopharmacology, 38(10), 897–910. https://doi.org/10.1177/02698811241282637
2-year Impact Factor: 5.5|2024
Times cited: 4|2025-09-27
Indexed document: Yes
Quartile: Q1
Keywords: DMT / Psychedelic / Ayahuasca / Compassion / Dimethyltryptamine / Insight / Meditation / Mindfulness / Mystical experience

Meditating on psychedelics. A randomized placebo-controlled study of DMT and harmine in a mindfulness retreat

Meditating on psychedelics. A randomized placebo-controlled study of DMT and harmine in a mindfulness retreat
DocumentWithin-subject comparison of near-death and psychedelic experiences: acute and enduring effects2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-065
Location: BF-GMS
Title:
065 - Unintended returns of awareness during cardiopulmonary resuscitation
Duration: 2023-02
Researcher(s):
Charlotte Martial, Pauline Fritz, Alice Clerget
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Articles
Language: eng
Notes:
Ongoing project
Author: Martial, C.
Secondary author(s):
Fritz, P., Clerget, A.
Number of reproductions:
3
Keywords:
Disconnected consciousness / Connected consciousness / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2022-065.08
Location: BF-GMS
Title:
Within-subject comparison of near-death and psychedelic experiences: acute and enduring effects
Publication year: 2024
URL:
https://doi.org/10.1093/nc/niae033
Abstract/Results: ABSTRACT:
Mystical-like states of consciousness may arise through means such as psychedelic substances, but may also occur unexpectedly during near-death experiences (NDEs). So far, research studies comparing experiences induced by serotonergic psychedelics and NDEs, along with their enduring effects, have employed between-subject designs, limiting direct comparisons. We present results from an online survey exploring the phenomenology, attribution of reality, psychological insights, and enduring effects of NDEs and psychedelic experiences (PEs) in individuals who have experienced both at some point during their lifetime. We used frequentist and Bayesian analyses to determine significant differences and overlaps (evidence for null hypotheses) between the two. Thirty-one adults reported having experienced both an NDE (i.e. NDE-C scale total score =27/80) and a PE (intake of lysergic acid diethylamide, psilocybin/mushrooms, ayahuasca, N,N-dimethyltryptamine, or mescaline). Results revealed areas of overlap between both experiences for phenomenology, attribution of reality, psychological insights, and enduring effects. A finer-grained analysis of the phenomenology revealed a significant overlap in mystical-like effects, while low-level phenomena (sensory effects) were significantly different, with NDEs displaying higher scores of disembodiment and PEs higher scores of visual imagery. This suggests psychedelics as a useful model for studying mystical-like effects induced by NDEs, while highlighting distinctions in sensory experiences.
Accessibility: Document exists in file
Language:
eng
Author:
Martial, C.
Secondary author(s):
Carhart-Harris, R., Timmermann, C.
Document type:
Article
Number of reproductions:
3
Reference:
Martial, C., Carhart-Harris, R., & Timmermann, C. (2024). Within-subject comparison of near-death and psychedelic experiences: Acute and enduring effects. Neuroscience of Consciousness, 2024(1), niae033. https://doi.org/10.1093/nc/niae033
2-year Impact Factor: 4.3|2024
Times cited: 5|2025-09-27
Indexed document: Yes
Quartile: Q1
Keywords: Near-death experience / Psychedelic / Phenomenology / Impact / Memory

Within-subject comparison of near-death and psychedelic experiences: acute and enduring effects

Within-subject comparison of near-death and psychedelic experiences: acute and enduring effects
DocumentAn encounter with death: A comparative thematic and content analysis of naturalistic DMT experiences and the near-death experience2025

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-359
Location: BF-GMS
Title:
359 - A comparison of NN-DMT, Changa & 5-MeO-DMT and the Near-death Experience: Qualitative analyses and reviews of the neuroscience
Duration: 2020/01 - 2024/05
Researcher(s):
Pascal Michael, David Luke
Institution(s): Department of Psychology, Social Work and Counselling, Greenwich University, London (UK); Psychedelic Research Group, Imperial College London (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Michael, P.
Secondary author(s):
Luke, D.
Number of reproductions:
3
Keywords:
Near-death experience / Dimethyltryptamine/DMT / Phenomenology / Pineal Gland / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2018-359.06
Location: BF-GMS
Title:
An encounter with death: A comparative thematic and content analysis of naturalistic DMT experiences and the near-death experience
Publication year: 2025
URL:
https://doi.org/10.3389/fpsyg.2025.1532937
Abstract/Results: ABSTRACT:
Introduction: Classical near-death experiences (NDEs) refer to states of disconnected consciousness characterised by a range of features occurring in the context of being close to death. Various psychedelic substances, such as N,N-dimethyltryptamine (DMT), consistently replicate NDE features and may be considered 'near-death-like experiences.' However, a systematic qualitative analysis comparing the specifics of content with the broader themes of both psychedelic and NDEs has yet to be conducted.
Methods: We report the third thematic and content analysis of the DMT experience from a naturalistic field study, focusing on themes related to death and dying. Based on 36 semi-structured interviews, this analysis is then directly compared, qualitatively and in terms of content frequency, with a novel extension of a previous thematic analysis of 34 written NDE narratives.
Results: The 'canonical NDE themes' identified across the DMT experiences included Translocation, Bright Light(s), Sense of Dying, The Void, Disembodiment, Tunnel-like Structures, Light Being-esque Entities, Deceased Family, Life Review-like, and Hyper-empathic Experiences. A total of 95% of participants reported at least one of these. Twelve 'less typical NDE motifs' were also noted. Five classical NDE features were entirely absent from DMT, while DMT exhibited an even broader array of experience features that were absent from NDEs. DMT clearly shares a more basic phenomenological structure with NDEs but shows differences in the prevalence of certain features. Furthermore, DMT did not present any immediately recognisable linear sequencing of themes. Overall, DMT is distinctly unique in its qualitative content, characterised by its more prodigious and stereotypical nature, which includes kaleidoscopic, extraterrestrial, transcultural, fluctuating, and overwhelming elements.
Discussion: When examining the comparability between DMT and NDEs at a fundamentally more nuanced level of qualitative content (as opposed to broad themes or questionnaire items), the two experiences clearly diverge. However, a minority of NDEs, which are themselves unique, do share significant content with DMT. Taken together, DMT could be considered an 'NDE-mimetic.' The weaker comparability is likely due not only to differences in context but also to the complex neural processes occurring near death, in which endogenous DMT may only play a small role. In light of this level of parallelism with NDEs, some potential clinical applications of DMT are also discussed.
Accessibility: Document exists in file
Language:
eng
Author:
Michael, P.
Secondary author(s):
Luke, D., Robinson, O.
Document type:
Article
Number of reproductions:
3
Reference:
Michael, P., Luke, D., & Robinson, O. (2025). An encounter with death: a comparative thematic and content analysis of naturalistic DMT experiences and the near-death experience. Frontiers in Psychology, 16, 1532937. https://doi.org/10.3389/fpsyg.2025.1532937
2-year Impact Factor: 2.9|2024
Impact factor notes: Impact factor not available yet for 2025
Times cited: 0|2025-09-27
Indexed document: Yes
Quartile: Q1
Keywords: DMT / Dimethyltryptamine / NDE / Naturalistic / Near-death experience / Psychedelic / Thematic analysis

An encounter with death: A comparative thematic and content analysis of naturalistic DMT experiences and the near-death experience

An encounter with death: A comparative thematic and content analysis of naturalistic DMT experiences and the near-death experience