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DocumentFinal report - Biological and psychological features of anxious symptoms in children2000

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1998
Location: Arquivo PCA - Pastas 1 a 11/1998
Title:
1998 Grants
Start date: 1999-01 - 2005-12
Dimension/support:
11 caixas de arquivo

Reference code: PT/FB/BL-1998-002
Location: Arquivo PCA - Pasta 1/1998
Title:
002 - Biological and psychological features of anxious symptoms in children
Duration: 1998-12 - 2000-12
Researcher(s):
Jerome Kagan, Nancy Snidman, Mark McManis
Institution(s): Harvard University (USA)
Contents: Contents:
Application form
Financial report and expenditure documents
Final report
2 Articles
Language: eng
Author:
Kagan, J.
Secondary author(s):
Snidman, N., McManis, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Psychosocial development

Reference code: PT/FB/BL-1998-002.01
Location: Arquivo PCA - Pasta 1/1998
Title:
Final report - Biological and psychological features of anxious symptoms in children
Publication year: 2000
URL:
http://www.bial.com/imagem/Bolsa0298_19022014.pdf
Abstract/Results: RESULTS:
A group of 237 children were seen at 11 years of age. These children had been followed from 4 months to 11 years. Some of the children had been categorized at 4 months as high reactive and some as low reactive. The high reactives, compared with the low reactives, were more likely to show at age 11 greater activation of the right hemisphere, a larger evoked potential from the inferior colliculus, greater magnitude of waveforms in the event related potential to discrepant scenes, and greater activation of the sympathetic nervous system.
These data imply that the high reactive infants preserved an inherited excitability of the amygdala and its projections from infancy to early adolescence. Furthermore high reactives were very shy and had anxious symptoms.
These results point to the stability of temperamental biases favoring shy/avoidant vs, bold/sociable behavior.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Kagan, J.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Anxious symptoms in children / Reactivity

Relatório final - Biological and Psychological Features of Anxious Symptoms in Children

Relatório final - Biological and Psychological Features of Anxious Symptoms in Children

DocumentBehavioral and psysiological consequences of infant temperament: The distinction between anima and persona2001

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1998
Location: Arquivo PCA - Pastas 1 a 11/1998
Title:
1998 Grants
Start date: 1999-01 - 2005-12
Dimension/support:
11 caixas de arquivo

Reference code: PT/FB/BL-1998-002
Location: Arquivo PCA - Pasta 1/1998
Title:
002 - Biological and psychological features of anxious symptoms in children
Duration: 1998-12 - 2000-12
Researcher(s):
Jerome Kagan, Nancy Snidman, Mark McManis
Institution(s): Harvard University (USA)
Contents: Contents:
Application form
Financial report and expenditure documents
Final report
2 Articles
Language: eng
Author:
Kagan, J.
Secondary author(s):
Snidman, N., McManis, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Psychosocial development

Reference code: PT/FB/BL-1998-002.06
Location: Arquivo PCA - Pasta 1/1998
Title:
Behavioral and psysiological consequences of infant temperament: The distinction between anima and persona
Publication year: 2001
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/3%C2%BA_simposio.a109.html
Accessibility: Document does not exist in file
Language:
eng
Author:
Snidman, N.
Secondary author(s):
Kagan, J., McManis, M., Woodward, S., Lewis, M., Shissler, T.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Snidman, N., Kagan, J., McManis, M., Woodward, S., Lewis, M., & Shissler, T. (2001). Behavioral and psysiological consequences of infant temperament: The distinction between anima and persona. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 3rd Symposium of Fundação Bial (p. 399). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Psychopathology / Reactivity / Temperament

Behavioral and psysiological consequences of infant temperament: The distinction between anima and persona

Behavioral and psysiological consequences of infant temperament: The distinction between anima and persona
DocumentBiological and psychological features of anxious symptoms in children2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-1998
Location: Arquivo PCA - Pastas 1 a 11/1998
Title:
1998 Grants
Start date: 1999-01 - 2005-12
Dimension/support:
11 caixas de arquivo

Reference code: PT/FB/BL-1998-002
Location: Arquivo PCA - Pasta 1/1998
Title:
002 - Biological and psychological features of anxious symptoms in children
Duration: 1998-12 - 2000-12
Researcher(s):
Jerome Kagan, Nancy Snidman, Mark McManis
Institution(s): Harvard University (USA)
Contents: Contents:
Application form
Financial report and expenditure documents
Final report
2 Articles
Language: eng
Author:
Kagan, J.
Secondary author(s):
Snidman, N., McManis, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Psychosocial development

Reference code: PT/FB/BL-1998-002.07
Location: Arquivo PCA - Pasta 1/1998
Title:
Biological and psychological features of anxious symptoms in children
Publication year: 2002
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/4%C2%BA_simposio.a110.html
Accessibility: Document does not exist in file
Language:
eng
Author:
Kagan, J.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Kagan, J. (2002). Biological and psychological features of anxious symptoms in children. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 4th Symposium of Fundação Bial (p. 406). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Psychopathology / Reactivity / Temperament

Biological and psychological features of anxious symptoms in children

Biological and psychological features of anxious symptoms in children
DocumentNewborn predictors of reactivity at four months 2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-028
Location: Arquivo PCA - Pasta 6/2000
Title:
028 - Newborn predictors of reactivity at 4 months
Duration: 2001-01 - 2002-05
Researcher(s):
Jerome Kagan, Nancy Snidman
Institution(s): Universidade de Harvard, Cambridge, (USA)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report (2 copies)
3 Articles
Unpublished document (oral communication)
Language: eng
Author:
Kagan, J.
Secondary author(s):
Snidman, N.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Psychosocial development

Reference code: PT/FB/BL-2000-028.07
Location: Arquivo PCA - Pasta 6/2000
Title:
Newborn predictors of reactivity at four months
Publication year: 2002
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/4%C2%BA_simposio.a110.html
Accessibility: Document does not exist in file
Language:
eng
Author:
Kagan, J.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Kagan, J. (2002). Newborn predictors of reactivity at four months. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 4th Symposium of Fundação Bial (p. 440). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Developmental psychology / Reactivity

Newborn predictors of reactivity at four months

Newborn predictors of reactivity at four months
DocumentInsomnia really hurts: Effect of a bad night's sleep on pain increases with insomnia severity2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-190
Location: BF-GMS
Title:
190 - Sleeping body, sentient mind? Searching for the neural bases of conscious experiences during sleep
Duration: 2017-10 - 2019-06
Researcher(s):
Eus Van Someren, Yishul Wei
Institution(s): Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Author: Van Someren, E.
Secondary author(s):
Wei, Y.
Number of reproductions:
1
Keywords:
Interoception / Insomnia / Neural correlates of consciousness / Salience / Psychophysiology

Reference code: PT/FB/BL-2016-190.03
Location: BF-GMS
Title:
Insomnia really hurts: Effect of a bad night's sleep on pain increases with insomnia severity
Publication year: 2018
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121188/
Abstract/Results: ABSTRACT:
Insomnia and chronic pain are highly prevalent conditions and are often comorbid. Somatic complaints other than pain are also often observed in insomnia. Poor sleep and pain are known to mutually reinforce each other. However, it is unknown whether the habitual severity of insomnia modulates the acute effect of a particularly bad night's sleep on the next day's pain severity, and whether it modulates the acute effect of pain on the following night's sleep quality. Using data from 3,508 volunteers (2,684 female, mean age 50.09 y), we addressed these questions in addition to the associations between the habitual severity of insomnia, somatic complaints, and pain. Results indicated that people suffering from more severe habitual insomnia showed stronger mutual acute within-day reactivity of pain and poor sleep quality. The same increased reactivity was found in people with more severe habitual pain. Interestingly, the acute within-day mutual reactivity of pain and sleep quality showed consistent asymmetry. Pain worsened more after a particularly bad night's sleep than it improved after a particularly good night's sleep. Likewise, sleep worsened more after a day with more-than-usual pain than it improved after a day with less-than-usual pain. Future interventions may profit from addressing this asymmetric mutual reactivity especially in people with severe comorbid insomnia and chronic pain.
Accessibility: Document exists in file
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Blanken, T. F., Van Someren, E. J. W.
Document type:
Article
Number of reproductions:
1
Reference:
Wei, Y., Blanken, T. F., & Van Someren, E. J. W. (2018). Insomnia really hurts: Effect of a bad night's sleep on pain increases with insomnia severity. Frontiers in Psychiatry, 9: 377. https://doi.org/10.3389/fpsyt.2018.00377
2-year Impact Factor: 3.161|2018
Times cited: 38|2025-09-17
Indexed document: Yes
Quartile: Q2
Keywords: Sleep quality / Pain / Insomnia disorder / Somatic complaints / Symptom dynamics / Reactivity / Sensitization

Insomnia really hurts: Effect of a bad night's sleep on pain increases with insomnia severity

Insomnia really hurts: Effect of a bad night's sleep on pain increases with insomnia severity
DocumentBrain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-190
Location: BF-GMS
Title:
190 - Sleeping body, sentient mind? Searching for the neural bases of conscious experiences during sleep
Duration: 2017-10 - 2019-06
Researcher(s):
Eus Van Someren, Yishul Wei
Institution(s): Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Articles
Author: Van Someren, E.
Secondary author(s):
Wei, Y.
Number of reproductions:
1
Keywords:
Interoception / Insomnia / Neural correlates of consciousness / Salience / Psychophysiology

Reference code: PT/FB/BL-2016-190.07
Location: BF-GMS
Title:
Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/pii/S2213158219303699
Abstract/Results: ABSTRACT:
Insomnia Disorder (ID) is a prevalent and persistent condition, yet its neural substrate is not well understood. The cognitive, emotional, and behavioral characteristics of ID suggest that vulnerability involves distributed brain networks rather than a single brain area or connection. The present study utilized probabilistic diffusion tractography to compare the whole-brain structural connectivity networks of people with ID and those of matched controls without sleep complaints.
Diffusion-weighted images and T1-weighed images were acquired in 51 people diagnosed with ID (21–69 years of age, 37 female) and 48 matched controls without sleep complaints (22–70 years of age, 31 female). Probabilistic tractography was performed to construct the whole-brain structural connectivity network of each participant. Case–control differences in connectivity strength and network efficiency were evaluated with permutation tests.
People with ID showed structural hyperconnectivity within a subnetwork that spread over frontal, parietal, temporal, and subcortical regions and was anchored at the right angular gyrus. The result was robust across different edge-weighting strategies. Moreover, converging support was given by the finding of heightened right angular gyrus nodal efficiency (harmonic centrality) across varying graph density in people with ID. Follow-up correlation analyses revealed that subnetwork connectivity was associated with self-reported reactive hyperarousal.
The findings demonstrate that the right angular gyrus is a hub of enhanced structural connectivity in ID. Hyperconnectivity within the identified subnetwork may contribute to increased reactivity to stimuli and may signify vulnerability to ID.
Accessibility: Document exist in file
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Bresser, T., Wassing, R., Stoffers, D., Van Someren, E. J. W., Foster-Dingleya, J. C.
Document type:
Article
Number of reproductions:
1
Reference:
Wei, Y., Bresser, T., Wassing, R., Stoffers, D., Van Someren, E. J. W., & Foster-Dingleya, J. C. (2019). Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus. NeuroImage: Clinical, 24: 102019. https://doi.org/10.1016/j.nicl.2019.102019
2-year Impact Factor: 4.350|2019
Times cited: 21|2025-09-17
Indexed document: Yes
Quartile: Q2
Keywords: Tractography / Diffusion-weighted MRI / Connectome / Angular gyrus / Insomnia disorder / Reactivity

Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus

Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus
DocumentBrain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-253
Location: Arquivo PCA - Pasta 25/2012
Title:
253 - REM-sleep, the regulation of self-conscious emotion and hyperarousal in psychophysiological insomnia
Duration: 2015-11 - 2017-09
Researcher(s):
Lucia Talamini, Ekaterini Georgopoulou, Eus Van Someren
Institution(s): University of Amsterdam, Psychology, Dept. Brain and Cognition (The Netherlands) and Netherlands Institute for Neuroscience, Dept. Sleep & Cognition, Amsterdam (The Netherlands)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Talamini, L.
Secondary author(s):
Georgopoulou, E., Van Someren, E.
Number of reproductions:
1
Keywords:
Psychophysiology / Psychophysiological insomnia / Hyperarousal / Self-conscious emotion / REM-sleep

Reference code: PT/FB/BL-2012-253.08
Location: Arquivo PCA - Pasta 25/2012
Title:
Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/pii/S2213158219303699
Abstract/Results: ABSTRACT:
Insomnia Disorder (ID) is a prevalent and persistent condition, yet its neural substrate is not well understood. The cognitive, emotional, and behavioral characteristics of ID suggest that vulnerability involves distributed brain networks rather than a single brain area or connection. The present study utilized probabilistic diffusion tractography to compare the whole-brain structural connectivity networks of people with ID and those of matched controls without sleep complaints.
Diffusion-weighted images and T1-weighed images were acquired in 51 people diagnosed with ID (21–69 years of age, 37 female) and 48 matched controls without sleep complaints (22–70 years of age, 31 female). Probabilistic tractography was performed to construct the whole-brain structural connectivity network of each participant. Case–control differences in connectivity strength and network efficiency were evaluated with permutation tests.
People with ID showed structural hyperconnectivity within a subnetwork that spread over frontal, parietal, temporal, and subcortical regions and was anchored at the right angular gyrus. The result was robust across different edge-weighting strategies. Moreover, converging support was given by the finding of heightened right angular gyrus nodal efficiency (harmonic centrality) across varying graph density in people with ID. Follow-up correlation analyses revealed that subnetwork connectivity was associated with self-reported reactive hyperarousal.
The findings demonstrate that the right angular gyrus is a hub of enhanced structural connectivity in ID. Hyperconnectivity within the identified subnetwork may contribute to increased reactivity to stimuli and may signify vulnerability to ID.
Accessibility: Document exists in file
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Bresser, T., Wassing, R., Stoffers, D., Van Someren, E. J. W., Foster-Dingleya, J. C.
Document type:
Article-d
Number of reproductions:
1
Reference:
Wei, Y., Bresser, T., Wassing, R., Stoffers, D., Van Someren, E. J. W., & Foster-Dingleya, J. C. (2019). Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus. NeuroImage: Clinical, 24: 102019. https://doi.org/10.1016/j.nicl.2019.102019
2-year Impact Factor: 4.350|2019
Times cited: 21|2025-09-17
Indexed document: Yes
Quartile: Q2
Keywords: Tractography / Diffusion-weighted MRI / Connectome / Angular gyrus / Insomnia disorder / Reactivity

Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus

Brain structural connectivity network alterations in insomnia disorder reveal a central role of the right angular gyrus