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BIAL Foundation
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DocumentI keep a close watch on this heart of mine: increased interoception in insomnia2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-252
Location: SEC PCA 252/12
Title:
252 - Sleep state misperception mispercieved
Duration: 2014-06 - 2017-01
Researcher(s):
Eus J. W. Van Someren, J. Ramautar
Institution(s): Netherlands Institute for Neuroscience, Dept. Sleep & Cognition, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress reports
Final reports
2 Articles
Language: eng
Author:
Van Someren, E.
Secondary author(s):
Ramautar, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Sleep and dreams / Biopsychological problems / Mental health / Sleep disorders / Brain structure and function / Cognitive processes / Memory / Consciousness

Reference code: PT/FB/BL-2012-252.03
Location: SEC PCA 252/12
Title:
I keep a close watch on this heart of mine: increased interoception in insomnia
Publication year: 2016
URL:
https://www.ncbi.nlm.nih.gov/pubmed/27634787
Abstract/Results: ABSTRACT:
STUDY OBJECTIVES:
Whereas both insomnia and altered interoception are core symptoms in affective disorders, their neural mechanisms remain insufficiently understood and have not previously been linked. Insomnia Disorder (ID) is characterized by sensory hypersensitivity during wakefulness and sleep. Previous studies on sensory processing in ID addressed external stimuli only, but not interoception. Interoceptive sensitivity can be studied quantitatively by measuring the cerebral cortical response to one's heartbeat (heartbeat-evoked potential, HEP). We here investigated whether insomnia is associated with increased interoceptive sensitivity as indexed by the HEP amplitude.
METHODS:
Sixty-four participants aged 21-70 years were recruited through www.sleepregistry.nl including 32 people suffering from ID and 32 age- and sex-matched controls without sleep complaints. HEPs were obtained from resting-state high-density electroencephalography (HD-EEG) recorded during evening wakeful rest in eyes-open (EO) and eyes-closed (EC) conditions of 5-minute duration each. Significance of group differences in HEP amplitude and their topographical distribution over the scalp were assessed by means of cluster-based permutation tests.
RESULTS:
In particular during EC, and to a lesser extent during EO, people with ID had a larger amplitude late HEP component than controls at frontal electrodes 376-500 ms after the R-wave peak. Source localization suggested increased neural activity time-locked to heartbeats in people with ID mainly in anterior cingulate/medial frontal cortices.
CONCLUSIONS:
People with insomnia show insufficient adaptation of their brain responses to the ever-present heartbeats. Abnormalities in the neural circuits involved in interoceptive awareness including the salience network may be of key importance to the pathophysiology of insomnia.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Ramautar, J., Colombo, M., Stoffers, D., Gomez-Herrero, G., van der Meijden, W. P., Te Lindert, B. H., van der Werf, Y., Van Someren, E.
Document type:
Article
Number of reproductions:
1
Percentiles:
5
Reference:
Wei, Y., Ramautar, J., Colombo, M., Stoffers, D., Gomez-Herrero, G., van der Meijden, W. P., Te Lindert, B. H., van der Werf, Y., & Van Someren, E. (2016). I keep a close watch on this heart of mine: increased interoception in insomnia. Sleep, 39(12), 2113-2124. https://doi.org/10.5665/sleep.6308
2-year Impact Factor: 4.923|2016
Times cited: 51|2024-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Insomnia disorder / Interoception / Heartbeat-evoked potential / Event-related potential / High-density EEG / Hyperarousal / Resting state / Salience network
DocumentEEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-190
Location: BF-GMS
Title:
190 - Sleeping body, sentient mind? Searching for the neural bases of conscious experiences during sleep
Duration: 2017-10 - 2019-06
Researcher(s):
Eus Van Someren, Yishul Wei
Institution(s): Department of Sleep and Cognition, Netherlands Institute for Neuroscience, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Article
Author: Van Someren, E.
Secondary author(s):
Wei, Y.
Number of reproductions:
1
Keywords:
Interoception / Insomnia / Neural correlates of consciousness / Salience / Psychophysiology

Reference code: PT/FB/BL-2016-190.04
Location: BF-GMS
Title:
EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content
Publication year: 2018
URL:
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00395/full
Abstract/Results: ABSTRACT:
People with Insomnia Disorder (ID) not only experience abundant nocturnal mentation, but also report altered spontaneous mental content during daytime wakefulness, such as an increase in bodily experiences (heightened somatic awareness). Previous studies have shown that resting-state EEG can be temporally partitioned into quasi-stable microstates, and that these microstates form a small number of canonical classes that are consistent across people. Furthermore, the microstate classes have been associated with individual differences in resting mental content including somatic awareness. To address the hypothesis that altered resting mental content in ID would be reflected in an altered representation of the corresponding EEG microstates, we analyzed resting-state high-density EEG of 32 people with ID and 32 age- and sex-matched controls assessed during 5-min eyes-closed wakefulness. Using data-driven topographical k-means clustering, we found that 5 microstate classes optimally explained the EEG scalp voltage map sequences across participants. For each microstate class, 3 dynamic features were obtained: mean duration, frequency of occurrence, and proportional coverage time. People with ID had a shorter mean duration of class C microstates, and more frequent occurrence of class D microstates. The finding is consistent with previously established associations of these microstate properties with somatic awareness, and increased somatic awareness in ID. EEG microstate assessment could provide objective markers of subjective experience dimensions in studies on consciousness during the transition between wake and sleep, when self-report is not possible because it would interfere with the very process under study. Addressing somatic awareness may benefit psychotherapeutic treatment of insomnia.
Accessibility: Document exists in file
Language:
eng
Author:
Wei, Y.
Secondary author(s):
Ramautar, J. R., Colombo, M. A., Te Lindert, B. H. W., Van Someren, E. J. W.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Wei, Y., Ramautar, J. R., Colombo, M. A., Te Lindert, B. H. W., & Van Someren, E. J. W. (2018). EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content. Frontiers in Psychiatry, 9: 395. https://doi.org/10.3389/fpsyt.2018.00395
2-year Impact Factor: 3.161|2018
Times cited: 21|2024-02-09
Indexed document: Yes
Quartile: Q2
Keywords: Electrical neuroimaging / High-density EEG / Insomnia disorder / Mental content / Microstate / Resting state / Somatic awareness / Wakefulness

EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content

EEG microstates indicate heightened somatic awareness in insomnia: Toward objective assessment of subjective mental content
DocumentMemory consolidation during waking rest2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-083
Location: Arquivo PCA - Pasta 20/2012
Title:
083 - The impact of future relevance on dream content and sleep-dependent memory processing
Duration: 2013-05 - 2016-11
Researcher(s):
Erin J. Wamsley, Robert Stickgold, Nam Nguyen
Institution(s): Beth Israel Deaconess Medical Center, Boston (USA)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
2 Bachelor dissertations
Article
Language: eng
Author:
Wamsley, E.
Secondary author(s):
Stickgold, R., Nguyen, N.
Number of reproductions:
1
Keywords:
Psychophysiology / Sleep and dreams / Cognitive processes / Memory

Reference code: PT/FB/BL-2012-083.06
Location: Arquivo PCA - Pasta 20/2012
Title:
Memory consolidation during waking rest
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/pii/S1364661319300142
Abstract/Results: ABSTRACT
Recent studies show that brief periods of rest after learning facilitate consolidation of new memories. This effect is associated with memory-related brain activity during quiet rest and suggests that in our daily lives, moments of unoccupied rest may serve an essential cognitive function.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Wamsley, E.
Document type:
Article-d
Number of reproductions:
1
Reference:
Wamsley, E. (2019). Memory consolidation during waking rest. Trends in Cognitive Sciences, 23(3), 171-173. https://doi.org/10.1016/j.tics.2018.12.007
2-year Impact Factor: 15.218|2019
Times cited: 53|2024-02-12
Indexed document: Yes
Quartile: Q1
Keywords: Declarative memory / Memory consolidation / Mind wandering / Offline processing / Resting state
DocumentMemory consolidation during waking rest2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-211
Location: BF-GMS
Title:
211 - Waking conscious states and offline memory processing
Duration: 2017-08 - 2020-09
Researcher(s):
Erin Wamsley, Theodore Summer
Institution(s): Department of Psychology, Furman University, Greenville (USA)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Author: Wamsley, E. J.
Secondary author(s):
Summer, T.
Number of reproductions:
1
Keywords:
Consciousness / Conscious States / Attention / Electroencephalography / Psychophysiology

Reference code: PT/FB/BL-2016-211.03
Location: BF-GMS
Title:
Memory consolidation during waking rest
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/abs/pii/S1364661319300142
Abstract/Results: ABSTRACT:
Recent studies show that brief periods of rest after learning facilitate consolidation of new memories. This effect is associated with memory-related brain activity during quiet rest and suggests that in our daily lives, moments of unoccupied rest may serve an essential cognitive function.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Wamsley, E.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Wamsley, E. J. (2019). Memory consolidation during waking rest. Trends in Cognitive Sciences, 23(3), 171-173. https://doi.org/10.1016/j.tics.2018.12.007
2-year Impact Factor: 15.218|2019
Times cited: 53|2024-02-08
Indexed document: Yes
Quartile: Q1
Keywords: Memory consolidation / Offline processing / Resting state / Mind wandering / Declarative memory
DocumentHigh-density EEG in a Charles Bonnet Syndrome Patient during and without visual hallucinations: A case-report study2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Number of reproductions:
3
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-91
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
High-density EEG in a Charles Bonnet Syndrome Patient during and without visual hallucinations: A case-report study
Publication year: 2021
URL:
https://www.mdpi.com/2073-4409/10/8/1991
Abstract/Results: ABSTRACT:
Charles Bonnet syndrome (CBS) is a rare clinical condition characterized by complex visual hallucinations in people with loss of vision. So far, the neurobiological mechanisms underlying the hallucinations remain elusive. This case-report study aims at investigating electrical activity changes in a CBS patient during visual hallucinations, as compared to a resting-state period (without hallucinations). Prior to the EEG, the patient underwent neuropsychological, ophthalmologic, and neurological examinations. Spectral and connectivity, graph analyses and signal diversity were applied to high-density EEG data. Visual hallucinations (as compared to resting-state) were characterized by a significant reduction of power in the frontal areas, paralleled by an increase in the midline posterior regions in delta and theta bands and by an increase of alpha power in the occipital and midline posterior regions. We next observed a reduction of theta connectivity in the frontal and right posterior areas, which at a network level was complemented by a disruption of small-worldness (lower local and global efficiency) and by an increase of network modularity. Finally, we found a higher signal complexity especially when considering the frontal areas in the alpha band. The emergence of hallucinations may stem from these changes in the visual cortex and in core cortical regions encompassing both the default mode and the fronto-parietal attentional networks.
Accessibility: Document exists in file
Language:
eng
Author:
Piarulli, A.
Secondary author(s):
Annen, J., Kupers, R., Laureys, S., Martial, C.
Document type:
Article
Number of reproductions:
3
Percentiles:
7
Reference:
Piarulli, A., Annen, J., Kupers, R., Laureys, S., & Martial, C. (2021). High-density EEG in a Charles Bonnet Syndrome Patient during and without visual hallucinations: A case-report study. Cells, 10(8), 1991. https://doi.org/10.3390/cells10081991
2-year Impact Factor: 6.600|2020
Impact factor notes: Impact factor not available yet for 2021
Times cited: 4|2024-02-14
Indexed document: Yes
Quartile: Q2
Keywords: Charles Bonnet syndrome / EEG / Visual hallucination / Resting state

High-density EEG in a Charles Bonnet Syndrome Patient during and without visual hallucinations: A case-report study

High-density EEG in a Charles Bonnet Syndrome Patient during and without visual hallucinations: A case-report study
DocumentInterplay between the salience and the default mode network in a social-cognitive task toward a close other2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-217
Location: BF-GMS
Title:
217 - Physiological indices of the deleterious effects of unrealistic media images on body satisfaction: A cross-cultural investigation
Duration: 2018-06 - 2023-07
Researcher(s):
Clédna Patrícia de Oliveira-Silva, Rachel Rodgers, Óscar Gonçalves, Pedro Dias, Rosana Magalhães, Eugénia Fernandes, Bárbara Machado, Joana Coutinho, Paulo Boggio
Institution(s): Centre for Studies in Human Development, Faculty of Education and Psychology, Universidade Católica Portuguesa, Porto (Portugal); Department of Applied Psychology, Northeastern University, Boston (USA)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Master's thesis
Articles
Author: Oliveira-Silva, P.
Secondary author(s):
Rodgers, R., Gonçalves, O., Dias, P., Magalhães, R., Fernandes, E., Machado, B., Coutinho, J., Boggio, P.
Number of reproductions:
1
Keywords:
Disclaimer labels / Body image / Emotion dysregulation / Cross-cultural / Psychophysiology

Reference code: PT/FB/BL-2016-217.05
Location: BF-GMS
Title:
Interplay between the salience and the default mode network in a social-cognitive task toward a close other
Publication year: 2022
URL:
https://pubmed.ncbi.nlm.nih.gov/35197871/
Abstract/Results: Abstract
Social cognition relies on two main subsystems to construct the understanding of others, which are sustained by different social brain networks. One of these social networks is the default mode network (DMN) associated with the socio-cognitive subsystem (i.e., mentalizing), and the other is the salience network (SN) associated with the socio-affective route (i.e., empathy). The DMN and the SN are well-known resting state networks that seem to constitute a baseline for the performance of social tasks. We aimed to investigate both networks' functional connectivity (FC) pattern in the transition from resting state to social task performance. A sample of 38 participants involved in a monogamous romantic relationship completed a questionnaire of dyadic empathy and underwent an fMRI protocol that included a resting state acquisition followed by a task in which subjects watched emotional videos of their romantic partner and elaborated on their partner's (Other condition) or on their own experience (Self condition). Independent component and ROI-to-ROI correlation analysis were used to assess alterations in task-independent (Rest condition) and task-dependent (Self and Other conditions) FC. We found that the spatial FC maps of the DMN and SN evidenced the traditional regions associated with these networks in the three conditions. Anterior and posterior DMN regions exhibited increased FC during the social task performance compared to resting state. The Other condition revealed a more limited SN's connectivity in comparison to the Self and Rest conditions. The results revealed an interplay between the main nodes of the DMN and the core regions of the SN, particularly evident in the Self and Other conditions.
Accessibility: Document exists in file
Language:
eng
Author:
Costa, C.
Secondary author(s):
Soares, J., Oliveira-Silva, P., Sampaio, A., Coutinho, J.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Costa, C., Soares, J., Oliveira-Silva, P., Sampaio, A., & Coutinho, J. (2022). Interplay between the salience and the default mode network in a social-cognitive task toward a close other. Frontiers in Psychiatry, 12, 718400. https://doi.org/10.3389/fpsyt.2021.718400
2-year Impact Factor: 4.700|2022
Times cited: 2|2024-02-15
Indexed document: Yes
Quartile: Q2
Keywords: Default mode network / Functional connectivity / Resting state / Salience network / Self/other processing / Social cognition

Interplay between the salience and the default mode network in a social-cognitive task toward a close other

Interplay between the salience and the default mode network in a social-cognitive task toward a close other
File102 - Identifying altered resting state connectivity dynamics as predictors of auditory verbal hallucinations (AVH)

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-102
Location: BF-GMS
Title:
102 - Identifying altered resting state connectivity dynamics as predictors of auditory verbal hallucinations (AVH)
Researcher(s): Sonja Kotz, Hanna Honcamp, Michael Schwartze, David Linden, Federico de Martino, Ana Pinheiro
Institution(s): Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Article
Language: eng
Author:
Kotz, S. A.
Secondary author(s):
Honcamp, H., Schwartze, M., Linden, D. E., De Martino, F., Pinheiro, A. P.
Number of reproductions:
1
Keywords:
Auditory verbal hallucinations / Resting state / Brain dynamics / Hidden semi-markov modeling / Psychophysiology
DocumentTemporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-292
Location: BF-GMS
Title:
292 - Oxytocin: On the psychophysiology of trust and cooperation
Duration: 2017-10 - 2023-11
Researcher(s):
Diana Prata, James Rilling, Manuel Lopes, Duarte Ferreira, Daniel Martins, Pedro Levy
Institution(s): FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências (Portugal); Emory University, Atlanta (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Prata, D.
Secondary author(s):
Rilling, J., Lopes, M., Ferreira, D. , Martins, D., Levy, P.
Number of reproductions:
1
Keywords:
Oxytocin / Mentalizing / Theory of mind / Dopamine / Psychophysiology

Reference code: PT/FB/BL-2016-292.16
Location: BF-GMS
Title:
Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study
Publication year: 2023
URL:
https://journals.sagepub.com/doi/full/10.1177/02698811231158233?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
Abstract/Results: ABSTRACT:
Background:
Human social behavior is modulated by oxytocin (OT). Intranasal administration of OT (IN-OT) is a noninvasive route shown to elicit changes in the autonomic nervous system (ANS) activity; however, IN-OT’s effect on the temporal profile of ANS activity at rest is yet to be described.
Aims:
We aimed to describe the temporal profile of IN-OT at six 10-min time windows from 15- to 100-min post-administration in 20 male participants at rest while continuously recording their pupillary in an eyes-open condition and cardiac activity in eyes-open and eyes-closed conditions.
Methods:
We used a double-blind, placebo-controlled, within-subjects design study where we extracted two proxies of parasympathetic nervous system (PNS) activity: high-frequency heart rate variability (HF-HRV) and pupillary unrest index (PUI); and a proxy of sympathetic nervous system activity: sample entropy of the pupillary unrest.
Results:
In the eyes-open condition, we found an effect of IN-OT on the proxies of PNS activity: decreased PUI in the three-time windows post-administration spanning 65–100 min, and as an exploratory finding, an increased HF-HRV in the 80–85 min time window.
Conclusions:
We suggest there is a role of OT in PNS regulation that may be consistent with OT’s currently theorized role in the facilitation of alertness and approach behavior.
Accessibility: Document exists in file
Language:
eng
Author:
Cosme, G.
Secondary author(s):
Arriaga, P., Rosa, P. J., Mehta, M. A., Prata, D.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Cosme, G., Arriaga, P., Rosa, P. J., Mehta, M. A., & Prata, D. (2023). Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study. Journal of Psychopharmacology, 37(6), 566-576. https://doi.org/10.1177/02698811231158233
2-year Impact Factor: 4.5|2023
Times cited: 0|2024-02-16
Indexed document: Yes
Quartile: Q2
Keywords: Electrocardiography / Neuropeptide / Pharmacodynamics / Pupil unrest / Resting state

Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study

Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study
DocumentThe secret life of predictive brains: What’s spontaneous activity for?2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-361
Location: BF-GMS
Title:
361 - When style matters: Do oculomotor fingerprint and brain dynamics explain visual exploration and memory strategies?
Duration: 2019-04 - 2023-11
Researcher(s):
Maurizio Corbetta, Andrea Zangrossi
Institution(s): Venetian Institute of Molecular Medicine - VIMM, Fondazione per la Ricerca Biomedica Avanzata, Padova (Italy); Padova Neuroscience Center – PNC, Università di Padova (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Corbetta, M.
Secondary author(s):
Zangrossi, A.
Number of reproductions:
1
Keywords:
Inter-individual variability / Memory / Visual exploration / Brain dynamics / Psychophysiology

Reference code: PT/FB/BL-2018-361.25
Location: BF-GMS
Title:
The secret life of predictive brains: What’s spontaneous activity for?
Publication year: 2021
URL:
https://doi.org/10.1016/j.tics.2021.05.007
Abstract/Results: ABSTRACT:
Brains at rest generate dynamical activity that is highly structured in space and time. We suggest that spontaneous activity, as in rest or dreaming, underlies top-down dynamics of generative models. During active tasks, generative models provide top-down predictive signals for perception, cognition, and action. When the brain is at rest and stimuli are weak or absent, top-down dynamics optimize the generative models for future interactions by maximizing the entropy of explanations and minimizing model complexity. Spontaneous fluctuations of correlated activity within and across brain regions may reflect transitions between ‘generic priors’ of the generative model: low dimensional latent variables and connectivity patterns of the most common perceptual, motor, cognitive, and interoceptive states. Even at rest, brains are proactive and predictive.
Accessibility: Document exists in file
Language:
eng
Author:
Pezzulo, G.
Secondary author(s):
Zorzi, M., Corbetta, M.
Document type:
Article
Number of reproductions:
1
Reference:
Pezzulo, G., Zorzi, M., & Corbetta, M. (2021). The secret life of predictive brains: What’s spontaneous activity for? Trends in Cognitive Sciences, 25(9), 730–743. https://doi.org/10.1016/j.tics.2021.05.007
2-year Impact Factor: 19.9|2022
Times cited: 76|2024-05-07
Indexed document: Yes
Quartile: Q1
Keywords: Spontaneous activity / Generative models / Resting state / Predictive brains

The secret life of predictive brains: what’s spontaneous activity for?

The secret life of predictive brains: what’s spontaneous activity for?
DocumentRevisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-102
Location: BF-GMS
Title:
102 - Identifying altered resting state connectivity dynamics as predictors of auditory verbal hallucinations (AVH)
Researcher(s): Sonja Kotz, Hanna Honcamp, Michael Schwartze, David Linden, Federico de Martino, Ana Pinheiro
Institution(s): Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Article
Language: eng
Author:
Kotz, S. A.
Secondary author(s):
Honcamp, H., Schwartze, M., Linden, D. E., De Martino, F., Pinheiro, A. P.
Number of reproductions:
1
Keywords:
Auditory verbal hallucinations / Resting state / Brain dynamics / Hidden semi-markov modeling / Psychophysiology

Reference code: PT/FB/BL-2022-102.02
Location: BF-GMS
Title:
Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling
Publication year: 2024
URL:
https://doi.org/10.1016/j.jneumeth.2024.110138
Abstract/Results: ABSTRACT:
Background: Resting state (RS) brain activity is inherently non-stationary. Hidden semi-Markov Models (HsMM) can characterize continuous RS data as a sequence of recurring and distinct brain states along with their spatiotemporal dynamics.
New method: Recent explorations suggest that HsMM state dynamics in the alpha frequency band link to auditory hallucination proneness (HP) in non-clinical individuals. The present study aimed to replicate these findings to elucidate robust neural correlates of hallucinatory vulnerability. Specifically, we aimed to investigate the reproducibility of HsMM states across different data sets and within-data set variants as well as the replicability of the association between alpha brain state dynamics and HP.
Results: We found that most brain states are reproducible in different data sets, confirming that the HsMM characterized robust and generalizable EEG RS dynamics on a sub-second timescale. Brain state topographies and temporal dynamics of different within-data set variants showed substantial similarities and were robust against reduced data length and number of electrodes. However, the association with HP was not directly reproducible across data sets. Comparison with existing methods: The HsMM optimally leverages the high temporal resolution of EEG data and overcomes time-domain restrictions of other state allocation methods.
Conclusion: The results indicate that the sensitivity of brain state dynamics to capture individual variability in HP may depend on the data recording characteristics and individual variability in RS cognition, such as mind wandering. Future studies should consider that the order in which eyes-open and eyes-closed RS data are acquired directly influences an individual’s attentional state and generation of spontaneous thoughts, and thereby might mediate the link to hallucinatory vulnerability.
Accessibility: Document exists in file
Language:
eng
Related objects:
BL-2020-146.06
Author: Honcamp, H.
Secondary author(s):
Schwartze, M., Amorim, M., Linden, D., Pinheiro, A., Kotz, S.
Document type:
Article
Number of reproductions:
1
Reference:
Honcamp, H., Schwartze, M., Amorim, M., Linden, D., Pinheiro, A., & Kotz, S. (2024). Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling. Journal of Neuroscience Methods, 110138. https://doi.org/10.1016/j.jneumeth.2024.110138
2-year Impact Factor: 3|2022
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2024-06-19
Indexed document: Yes
Quartile: Q3
Keywords: Hidden semi-markov model / Resting state / Alpha dynamics / Reproducibility / Hallucination proneness / Spontaneous thoughts

Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling

Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling
DocumentRevisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-146
Location: BF-GMS
Title:
146 - The me and the I: Dissociating ownership and agency in sensorimotor processing
Duration: 2021/09
Researcher(s):
Ana Pinheiro, Sonja Kotz, Michael Schwartze
Institution(s): Centro de Investigação em Ciência Psicológica - CICPSI, Faculdade de Psicologia da Universidade de Lisboa (Portugal); Faculty of Psychology and Neuroscience, University of Maastricht (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Article
Language: eng
Notes:
Ongoing project
Author: Pinheiro, A. P.
Secondary author(s):
Kotz, S., Schwartze, M.
Number of reproductions:
1
Keywords:
Self / Agency / Ownership / Electroencephalogram (EEG) / Psychophysiology

Reference code: PT/FB/BL-2020-146.06
Location: BF-GMS
Title:
Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling
Publication year: 2024
URL:
https://doi.org/10.1016/j.jneumeth.2024.110138
Abstract/Results: ABSTRACT:
Background: Resting state (RS) brain activity is inherently non-stationary. Hidden semi-Markov Models (HsMM) can characterize continuous RS data as a sequence of recurring and distinct brain states along with their spatiotemporal dynamics.
New method: Recent explorations suggest that HsMM state dynamics in the alpha frequency band link to auditory hallucination proneness (HP) in non-clinical individuals. The present study aimed to replicate these findings to elucidate robust neural correlates of hallucinatory vulnerability. Specifically, we aimed to investigate the reproducibility of HsMM states across different data sets and within-data set variants as well as the replicability of the association between alpha brain state dynamics and HP.
Results: We found that most brain states are reproducible in different data sets, confirming that the HsMM characterized robust and generalizable EEG RS dynamics on a sub-second timescale. Brain state topographies and temporal dynamics of different within-data set variants showed substantial similarities and were robust against reduced data length and number of electrodes. However, the association with HP was not directly reproducible across data sets. Comparison with existing methods: The HsMM optimally leverages the high temporal resolution of EEG data and overcomes time-domain restrictions of other state allocation methods.
Conclusion: The results indicate that the sensitivity of brain state dynamics to capture individual variability in HP may depend on the data recording characteristics and individual variability in RS cognition, such as mind wandering. Future studies should consider that the order in which eyes-open and eyes-closed RS data are acquired directly influences an individual’s attentional state and generation of spontaneous thoughts, and thereby might mediate the link to hallucinatory vulnerability.
Accessibility: Document exists in file
Language:
eng
Related objects:
BL-2022-102.02
Author: Honcamp, H.
Secondary author(s):
Schwartze, M., Amorim, M., Linden, D., Pinheiro, A., Kotz, S.
Document type:
Article-d
Number of reproductions:
1
Reference:
Honcamp, H., Schwartze, M., Amorim, M., Linden, D., Pinheiro, A., & Kotz, S. (2024). Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling. Journal of Neuroscience Methods, 110138. https://doi.org/10.1016/j.jneumeth.2024.110138
2-year Impact Factor: 2.39|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2025-01-08
Indexed document: Yes
Quartile: Q3
Keywords: Hidden semi-markov model / Resting state / Alpha dynamics / Reproducibility / Hallucination proneness / Spontaneous thoughts

Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling

Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling