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BIAL Foundation
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DocumentMore severe insomnia complaints in people with stronger long-range temporal correlations in wake resting-state EEG2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-252
Location: SEC PCA 252/12
Title:
252 - Sleep state misperception mispercieved
Duration: 2014-06 - 2017-01
Researcher(s):
Eus J. W. Van Someren, J. Ramautar
Institution(s): Netherlands Institute for Neuroscience, Dept. Sleep & Cognition, Amsterdam (The Netherlands)
Contents: Contents:
Application form
Correspondence
Progress reports
Final reports
2 Articles
Language: eng
Author:
Van Someren, E.
Secondary author(s):
Ramautar, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Sleep and dreams / Biopsychological problems / Mental health / Sleep disorders / Brain structure and function / Cognitive processes / Memory / Consciousness

Reference code: PT/FB/BL-2012-252.04
Title: More severe insomnia complaints in people with stronger long-range temporal correlations in wake resting-state EEG
Publication year: 2016
URL:
http://journal.frontiersin.org/article/10.3389/fphys.2016.00576/full
Abstract/Results: ABSTRACT:
The complaints of people suffering from Insomnia Disorder (ID) concern both sleep and daytime functioning. However, little is known about wake brain temporal dynamics in people with ID. We therefore assessed possible alterations in Long-Range Temporal Correlations (LRTC) in the amplitude fluctuations of band-filtered oscillations in electroencephalography (EEG) recordings. We investigated whether LRTC differ between cases with ID and matched controls. Within both groups, we moreover investigated whether individual differences in subjective insomnia complaints are associated with LRTC. Resting-state high-density EEG (256-channel) was recorded in 52 participants with ID and 43 age- and sex-matched controls, during Eyes Open (EO) and Eyes Closed (EC). Detrended fluctuation analysis was applied to the amplitude envelope of band-filtered EEG oscillations (theta, alpha, sigma, beta-1, beta-2) to obtain the Hurst exponents (H), as measures of LRTC. Participants rated their subjective insomnia complaints using the Insomnia Severity Index (ISI). Through general linear models, we evaluated whether H, aggregated across electrodes and frequencies, differed between cases and controls, or showed within-group associations with individual differences in ISI. Additionally, we characterized the spatio-spectral profiles of group differences and associations using non-parametric statistics. H did not differ between cases with ID and controls in any of the frequency bands, neither during EO nor EC. During EO, however, within-group associations between H and ISI indicated that individuals who experienced worse sleep quality had stronger LRTC. Spatio-spectral profiles indicated that the associations held most prominently for the amplitude fluctuations of parietal theta oscillations within the ID group, and of centro-frontal beta-1 oscillations in controls. While people suffering from insomnia experience substantially worse sleep quality than controls, their brain dynamics express similar strength of LRTC. In each group, however, individuals experiencing worse sleep quality tend to have stronger LRTC during eyes open wakefulness, in a spatio-spectral range specific for each group. Taken together, the findings indicate that subjective insomnia complaints involve distinct dynamical processes in people with ID and controls. The findings are in agreement with recent reports on decreasing LRTC with sleep depth, and with the hypothesis that sleep balances brain excitability.
Accessibility: Document exists in file
Language:
eng
Author:
Colombo, M.
Secondary author(s):
Wei, Y., Ramautar, J., Linkenkaer-Hansen, K., Tagliazucchi, E., Van Someren, E.
Document type:
Article
Number of reproductions:
1
Reference:
Colombo, M., Wei, Y., Ramautar, J., Linkenkaer-Hansen, K., Tagliazucchi, E., & Van Someren, E. (2016). More severe insomnia complaints in people with stronger long-range temporal correlations in wake resting-state EEG. Frontiers in Physiology, 7:576. https://doi.org/10.3389/fphys.2016.00576
2-year Impact Factor: 4.134|2016
Times cited: 31|2025-09-16
Indexed document: Yes
Quartile: Q1
Keywords: Resting-state / Insomnia / Sleep / HD-EEG / Long-range temporal correlations / Criticality / Detrended fluctuation analysis / Excitation-inhibition balance

More severe insomnia complaints in people with stronger long-range temporal correlations in wake resting-state EEG

More severe insomnia complaints in people with stronger long-range temporal correlations in wake resting-state EEG
DocumentDoes cognitive-behavioral therapy for insomnia change the brain? A case series study2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-170
Location: Arquivo PCA - Pasta 10/2010
Title:
170 - The role of fusion of multisensory percepts in dynamic facial/body expressions: an fMRI study
Duration: 2011-04 - 2013-11
Researcher(s):
Gina Maria Costa Caetano, Miguel Castelo-Branco, Beatrice de Gelder, Gregor Philipak
Institution(s): Instituto Biomédico de Investigação de Luz e Imagem - IBILI-, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
1 Article
1 Master's thesis
Language: eng
Author:
Caetano, G.
Secondary author(s):
Castelo-Branco, M., Gelder, B., Philipiak, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Cognitive processes / Perception / Brain structure and function

Reference code: PT/FB/BL-2010-170.06
Location: Arquivo PCA - Pasta 9/2010
Title:
Does cognitive-behavioral therapy for insomnia change the brain? A case series study
Publication year: 2019
URL:
https://link.springer.com/article/10.1007/s41782-019-00081-5
Abstract/Results: ABSTRACT:
PURPOSE
In this study, our aim was to examine neural correlates of cognitive–behavioral therapy for insomnia (CBT-I).
METHODS
It was investigated to what extent successfully tailored CBT-I modified the neural activity pattern observed before the intervention, when two insomnia patients were exposed to idiosyncratic stimuli pertaining to past/present and future concerns in an fMRI experiment.
RESULTS
Our findings suggested that successful CBT-I seems to normalize brain overactivity. This finding is enhanced by the visible attenuation of activity in brain regions implicated in self-referential processing and by the significant activation within visual areas across all experimental conditions.
CONCLUSION
It is likely that psychological treatment changes the brain’s function in insomnia. However, studies with larger sample sizes are needed to establish solid evidence.
Accessibility: Document exists in file
Language:
eng
Author:
Marques, D. R.
Secondary author(s):
Gomes, A. A., Clemente, V., Duarte, I. C., Caetano, G., Castelo-Branco, M.
Document type:
Article
Number of reproductions:
1
Reference:
Marques, D. R., Gomes, A. A., Clemente, V., Duarte, I. C., Caetano, G., & Castelo-Branco, M. (2019). Does cognitive-behavioral therapy for insomnia change the brain? A case series study. Sleep and Vigilance, 4, 35-42. https://doi.org/10.1007/s41782-019-00081-5
Indexed document: No
Keywords: Chronic insomnia / Cognitive-behavioral therapy for insomnia (CBT-I) / Default-mode network / Resting-state / Self / fMRI
DocumentThe effect of tailored cognitive-behavioral therapy for insomnia on brain’s resting-state networks2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-170
Location: Arquivo PCA - Pasta 10/2010
Title:
170 - The role of fusion of multisensory percepts in dynamic facial/body expressions: an fMRI study
Duration: 2011-04 - 2013-11
Researcher(s):
Gina Maria Costa Caetano, Miguel Castelo-Branco, Beatrice de Gelder, Gregor Philipak
Institution(s): Instituto Biomédico de Investigação de Luz e Imagem - IBILI-, Faculdade de Medicina, Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
1 Article
1 Master's thesis
Language: eng
Author:
Caetano, G.
Secondary author(s):
Castelo-Branco, M., Gelder, B., Philipiak, G.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Cognitive processes / Perception / Brain structure and function

Reference code: PT/FB/BL-2010-170.07
Location: Arquivo PCA - Pasta 9/2010
Title:
The effect of tailored cognitive-behavioral therapy for insomnia on brain’s resting-state networks
Publication year: 2020
URL:
https://link.springer.com/article/10.1007/s41782-020-00086-5
Abstract/Results: ABSTRACT:
Purpose
Insomnia is a highly prevalent disorder with important implications for health and well-being. It is well known the “hyperarousal hypothesis” in insomnia which assumes that patients present high levels of activation, in particular, cortical arousal.
Methods
A preliminary resting-state fMRI experiment comprising two non-medicated insomnia patients was performed to evaluate whether cognitive-behavioral therapy for insomnia (CBT-I) changes the activation patterns of the most known resting-state brain networks, particularly, the default-mode network (DMN).
Results
As main results, we found modifications in the anterior component of the DMN, in the visual network, and in the auditory network after successful CBT-I. The most notable result was a decreased activity in the medial prefrontal cortex from pre- to post-intervention.
Conclusion
Findings from this preliminary study suggest that psychological treatment may translate modifications in neural activity of insomnia patients.
Accessibility: Document does not exist in file
Language:
eng
Author:
Marques, D. R.
Secondary author(s):
Gomes, A. A., Clemente, V., Moutinho dos Santos, J., Duarte, I. C., Caetano, G., Castelo-Branco, M.
Document type:
Article
Number of reproductions:
1
Reference:
Marques, D. R., Gomes, A. A., Clemente, V., Moutinho dos Santos, J., Duarte, I. C., Caetano, G., & Castelo-Branco, M. (2020). The effect of tailored cognitive-behavioral therapy for insomnia on brain’s resting-state networks. Sleep and Vigilance, 4, 29-33. https://doi.org/10.1007/s41782-020-00086-5
Impact factor notes: N/A
Indexed document: No
Keywords: Chronic insomnia / Cognitive-behavioral therapy for insomnia (CBT-I) / Resting-state / Default-mode network / fMRI
DocumentThe prospective sense of agency is rooted in local and global properties of intrinsic functional brain networks2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-195
Location: BF-GMS
Title:
195 - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
Duration: 2017-04 - 2019-10
Researcher(s):
Sjoerd Ebisch, Mauro Gianni Perrucci
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Ebisch, S.
Secondary author(s):
Perrucci, M. G.
Number of reproductions:
1
Keywords:
Intrinsic self / Extrinsic self / Brain network interactions / Neuroimaging / Psychophysiology

Reference code: PT/FB/BL-2016-195.06
Location: BF-GMS
Title:
The prospective sense of agency is rooted in local and global properties of intrinsic functional brain networks
Publication year: 2020
URL:
https://www.mitpressjournals.org/doi/abs/10.1162/jocn_a_01590
Abstract/Results: ABSTRACT:
The sense of agency (SoA) refers to a constitutional aspect of the self describing the extent to which individuals feel in control over their actions and consequences thereof. Although the SoA has been associated with mental health and well-being, it is still unknown how interindividual variability in the SoA is embedded in the intrinsic brain organization. We hypothesized that the prospective component of an implicit SoA is associated with brain networks related to SoA and sensorimotor predictions on multiple spatial scales. We replicated previous findings by showing a significant prospective SoA as indicated by intentional binding effects. Then, using task-free fMRI and graph analysis, we analyzed associations between intentional binding effects and the intrinsic brain organization at regional, modular, and whole-brain scales. The results showed that intermodular connections of a frontoparietal module including the premotor cortex, supramarginal gyrus, and dorsal precuneus are associated with individual differences in prospective intentional binding. Notably, prospective intentional binding effects were also related to global brain modularity within a specific structural resolution range. These findings suggest that an implicit SoA generated through sensorimotor predictions relies on the intrinsic organization of the brain connectome on both local and global scales.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Di Plinio, S.
Secondary author(s):
Perrucci, M. G., Ebisch, S.
Document type:
Article
Number of reproductions:
1
Reference:
Di Plinio, S., Perrucci, M. G., & Ebisch, S. (2020). The prospective sense of agency is rooted in local and global properties of intrinsic functional brain networks. Journal of Cognitive Neuroscience, 32(9), 1764–1779. https://doi.org/10.1162/jocn_a_01590
2-year Impact Factor: 3.225|2020
Times cited: 11|2025-09-18
Indexed document: Yes
Quartile: Q2
Keywords: Intentional binding / Motor control / Resting-state / Modularity / Sense of agency
DocumentTemporal dynamics of intranasal oxytocin in human brain electrophysiology2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-292
Location: BF-GMS
Title:
292 - Oxytocin: On the psychophysiology of trust and cooperation
Duration: 2017-10 - 2023-11
Researcher(s):
Diana Prata, James Rilling, Manuel Lopes, Duarte Ferreira, Daniel Martins, Pedro Levy
Institution(s): FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências (Portugal); Emory University, Atlanta (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Prata, D.
Secondary author(s):
Rilling, J., Lopes, M., Ferreira, D. , Martins, D., Levy, P.
Number of reproductions:
1
Keywords:
Oxytocin / Mentalizing / Theory of mind / Dopamine / Psychophysiology

Reference code: PT/FB/BL-2016-292.11
Location: BF-GMS
Title:
Temporal dynamics of intranasal oxytocin in human brain electrophysiology
Publication year: 2022
URL:
https://academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhab404/6494709
Abstract/Results: ABSTRACT:
Oxytocin (OT) is a key modulator of human social cognition, popular in behavioral neuroscience. To adequately design and interpret intranasal OT (IN-OT) research, it is crucial to know for how long it affects human brain function once administered. However, this has been mostly deduced from peripheral body fluids studies, or uncommonly used dosages. We aimed to characterize IN-OT’s effects on human brain function using resting-state EEG microstates across a typical experimental session duration. Nineteen healthy males participated in a double-blind, placebo-controlled, within-subject, cross-over design of 24 IU of IN-OT in 12-min windows 15 min-to-1 h 42min after administration. We observed IN-OT effects on all microstates, across the observation span. During eyes-closed, IN-OT increased duration and contribution of A and contribution and occurrence of D, decreased duration and contribution of B and C; and increased transition probability C-to-B and C-to-D. In eyes-open, it increased A-to-C and A-to-D. As microstates A and D have been related to phonological auditory and attentional networks, respectively, we posit IN-OT may tune the brain for reception of external stimuli, particularly of social nature—tentatively supporting current neurocognitive hypotheses of OT. Moreover, we contrast our overall results against a comprehensive literature review of IN-OT time-course effects in the brain, highlighting comparability issues.
Accessibility: Document exists in file
Language:
eng
Author:
Zelenina, M.
Secondary author(s):
Kosilo, M., da Cruz, J., Antunes, M., Figueiredo, P., Mehta, M. A., Prata, D.
Document type:
Article
Number of reproductions:
1
Reference:
Zelenina, M., Kosilo, M., da Cruz, J., Antunes, M., Figueiredo, P., Mehta, M. A., & Prata, D. (2022). Temporal dynamics of intranasal oxytocin in human brain electrophysiology. Cerebral Cortex, 32(14), 3110-3126. https://doi.org/10.1093/cercor/bhab404
2-year Impact Factor: 3.700|2022
Times cited: 7|2025-09-24
Indexed document: Yes
Quartile: Q2
Keywords: Electroencephalography / Microstates / Oxytocin / Pharmacodynamics / Resting-state

Temporal dynamics of intranasal oxytocin in human brain electrophysiology

Temporal dynamics of intranasal oxytocin in human brain electrophysiology