Reference code: | PT/FB/BL-2006-154.03 |
Location: | Arquivo PCA - Pasta 5/2006
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Title:
| Interhemispheric propagation of seizures in mesial temporal lobe epilepsy
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Publication year: | 2009
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URL:
| http://www.ncbi.nlm.nih.gov/pubmed/19835273
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Abstract/Results: | ABSTRACT:
OBJECTIVES:
To investigate interhemispheric propagation of mesial temporal lobe epilepsy seizures in patients undergoing long-term video-EEG monitoring with combined scalp and foramen ovale electrodes.
AIM OF THE STUDY:
To reveal possible interhemispheric propagation patterns in mesial temporal lobe epilepsy, to improve presurgical evaluation of temporal epileptic patients.
METHODS:
Sixty-five seizures from 20 patients were analyzed. We defined two contralateral seizure propagation patterns: Type I for those seizures that spread to the contralateral foramen ovale electrodes earlier than to the contralateral scalp electrodes, and type II for the opposite.
PARTICIPANTS:
Twenty drug resistant epileptic patients were investigated in frame of their presurgical evaluation.
RESULTS:
The majority of seizures (80%) were classified as type I. Inter-foramen ovale electrode propagation time was significantly shorter for type I compared to type II seizures. Ninety percent of patients had either type I or type II seizures only. Patients with type I seizures significantly more often had mesiotemporal structural alterations evident on magnetic resonance imaging scans, and became more often seizure-free after surgery compared to patients with type II seizures whose surgical outcome was less favorable or surgery could not be indicated because of independent bilateral ictal seizure-onset.
CONCLUSIONS:
The two types of contralateral propagation patterns we are describing seem to represent two subtypes of mesial temporal lobe epilepsy with different morphological and prognostic features. The predominance of type I over type II seizures together with shorter propagation times for type I seizures indicate a role of a more direct and dominant interhemispheric pathway in mesial temporal lobe epilepsy.
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Accessibility: | Document does not exist in file
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Language:
| eng
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Author:
| Eross, L.
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Secondary author(s):
| Entz, L., Fabó, D., Jakus, R., Szucs, A., Rásonyi, G., Halász, P.
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Document type:
| Article
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Number of reproductions:
| 1
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Reference:
| Eross, L., Entz, L., Fabó, D., Jakus, R., Szucs, A., Rásonyi, G., ... Halász, P. (2009). Interhemispheric propagation of seizures in mesial temporal lobe epilepsy. Ideggyogyaszati Szemle-Clinical Neuroscience, 62(9-10), 319-325.
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2-year Impact Factor: | 0.236|2010
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Impact factor notes: | Impact factor computed since 2010
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Times cited: | 7|2024-02-05
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Indexed document: | Yes
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Quartile: | Q4
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Keywords: | Hippocampus / Epilepsy / Temporal lobe / Hippocampal commissure / Epilepsy surgery
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Interhemispheric propagation of seizures in mesial temporal lobe epilepsy |