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DocumentIndependent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-096
Location: Arquivo PCA - Pasta 6/2002
Title:
096 - Face processing in 3-day-olds: an electrophysiological approach
Duration: 2003-01 - 2005-02
Researcher(s):
Olivier Pascalis, de Haan Michelle, Saachi Reza
Institution(s): Department of Psychology, The University of Sheffield (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Article
Language: eng
Author:
Pascalis, O.
Secondary author(s):
Haan, M., Saatchi, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Brain structure and function

Reference code: PT/FB/BL-2002-096.03
Location: Arquivo PCA - Pasta 6/2002
Title:
Independent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism
Publication year: 2009
URL:
http://www.sciencedirect.com/science/article/pii/S000632230800886X
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=294&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
BACKGROUND:
Individuals with autistic spectrum disorder (ASD) experience atypical visual perception, yet the etiology of this remains unknown. The aim of this study was to investigate the neural correlates of visual perception in individuals with and without ASD by carrying out a detailed analysis of the dynamic brain processes elicited by perception of a simple visual stimulus.
METHODS:
We investigated perception in 20 individuals with ASD and 20 control subjects with electroencephalography (EEG). Visual evoked potentials elicited by Gabor patches of varying spatial frequency and stimulus-induced changes in a- and ?-frequency bands of independent components were compared in those with and without ASD.
RESULTS:
By decomposing the EEG data into independent components, we identified several processes that contributed to the average event related potential recorded at the scalp. Differences between the ASD and control groups were found only in some of these processes. Specifically, in those components that were in or near the striate or extrastriate cortex, stimulus spatial frequency exerted a smaller effect on induced increases in a- and ?-band power, and time to peak a-band power was reduced, in the participants with ASD. Induced a-band power of components that were in or near the cingulate gyrus was increased in the participants with ASD, and the components that were in or near the parietal cortex did not differ between the two groups.
CONCLUSION:
Atypical processing is evident in individuals with ASD during perception of simple visual stimuli. The implications of these data for existing theories of atypical perception in ASD are discussed.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Milne, E.
Secondary author(s):
Scope, A., Pascalis, O., Buckley, D., Makeig, S.
Document type:
Article
Number of reproductions:
1
Reference:
Milne, E., Scope, A., Pascalis, O., Buckley, D., & Makeig, S. (2009). Independent Component Analysis Reveals Atypical Electroencephalographic Activity During Visual Perception in Individuals with Autism. Biological Psychiatry, 65(1), 22-30. https://doi.org/10.1016/j.biopsych.2008.07.017
2-year Impact Factor: 8.926|2009
Times cited: 104|2024-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Alpha power / Autism / Cingulate Gyrus / Gamma power / Perception / Spatial frequency / Visual cortex

Novo ficheiro

Novo ficheiro

DocumentPattern motion selectivity in population responses of area 182006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-015
Location: Arquivo PCA - Pasta 9/2002
Title:
015 - Bases psicofisiológicas dos fenómenos de consciência visual
Duration: 2003-01 - 2005-12
Researcher(s):
Miguel Castelo-Branco, Lajos Kozac, Mafalda Mendes, Vasco Forjaz, Manuela Guerreiro
Institution(s): Centro de Oftalmologia, Coimbra (Portugal)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: por
Author:
Castelo-Branco, M.
Secondary author(s):
Kozak, L., Mendes, M., Forjaz, V., Guerreiro, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Brain structure and function / Cognitive processes / Diseases/Injuries / Chromosomal abnormalities

Reference code: PT/FB/BL-2002-015.08
Location: Arquivo PCA - Pasta 9/2002
Title:
Pattern motion selectivity in population responses of area 18
Publication year: 2006
URL:
http://www.ncbi.nlm.nih.gov/pubmed/17074056
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=349&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
It is commonly believed that the complexity of visual stimuli represented by individual neurons increases towards higher cortical areas. However, even in early visual areas an individual neuron's response is influenced by stimuli presented outside its classical receptive field. Thus, it has been proven difficult to characterize the coding of complex stimuli at the level of single neurons. We therefore investigated population responses using optical imaging in cat area 18 to complex stimuli, plaids. Plaid stimuli are composed of two superimposed gratings moving in different directions. They may be perceived as either two separate surfaces or as a global pattern moving in intermediate direction to the components' direction of motion. We found that in addition to activity maps representing the individual components' motion, plaid stimuli produced activity distributions matching the predictions from a pattern-motion model in central area 18. Thereby, relative component- and pattern-like modulations followed the degree of psychophysical pattern bias in the stimulus. Thus, our results strongly indicate that area 18 exhibits a substantial response to pattern-motion signals at the population level suggesting the presence of intrinsic or extrinsic mechanisms that allow for integration of motion responses from far outside the classical receptive field.
Accessibility: Document does not exist in file
Language:
eng
Author:
Schmidt, K.
Secondary author(s):
Castelo-Branco, M., Goebel, R., Payne, B., Lomber, S., Galuske, R.
Document type:
Article
Number of reproductions:
1
Reference:
Schmidt, K., Castelo-Branco, M., Goebel, R., Payne, B., Lomber, S., & Galuske, R. (2006). Pattern motion selectivity in population responses of area 18. European Journal of Neuroscience, 24(8), 2363-2374. https://doi.org/10.1111/j.1460-9568.2006.05112.x
2-year Impact Factor: 3.709|2006
Times cited: 8|2024-02-05
Indexed document: Yes
Quartile: Q2
Keywords: Cat / Optical imaging / Second-order motion / Visual cortex

DocumentIndependent component analysis reveals atypical EEG activity during visual perception in individuals with autism2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-047
Location: Arquivo PCA - Pasta 3/2004
Title:
047 - A combined psychophysiological and electrophysiological approach to investigate low-level visual perception in autism
Duration: 2005-06 - 2006-10
Researcher(s):
Olivier Pascalis, Elizabeth Milne, David Buckley, Laurence Vigon
Institution(s): Department of Psychology, The University of Sheffield (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Poster
1 Article
Journal Cahiers de Psychologie Cognitive/ Current Psychology of Cognition
Language: eng
Author:
Pascalis, O.
Secondary author(s):
Milne, E., Buckley, D., Vigon, L.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Biopsychological problems / Childhood and adolescent disorders / Autism spectrum disorder (ASD) / Cognitive processes / Perception

Reference code: PT/FB/BL-2004-047.02
Location: Arquivo PCA - Pasta 3/2004
Title:
Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism
Publication year: 2009
URL:
http://www.biologicalpsychiatryjournal.com/article/S0006-3223(08)00886-X/abstract
Abstract/Results: ABSTRACT:
BACKGROUND:
Individuals with autistic spectrum disorder (ASD) experience atypical visual perception, yet the etiology of this remains unknown. The aim of this study was to investigate the neural correlates of visual perception in individuals with and without ASD by carrying out a detailed analysis of the dynamic brain processes elicited by perception of a simple visual stimulus.
METHODS:
We investigated perception in 20 individuals with ASD and 20 control subjects with electroencephalograph(EEG). Visual evoked potentials elicited by Gabor patches of varying spatial frequency and stimulus-induced changes in a- and ?-frequency bands of independent components were compared in those with and without ASD.
RESULTS:
By decomposing the EEG data into independent components, we identified several processes that contributed to the average event related potential recorded at the scalp. Differences between the ASD and control groups were found only in some of these processes. Specifically, in those components that were in or near the striate or extrastriate cortex, stimulus spatial frequency exerted a smaller effect on induced increases in a- and ?-band power, and time to peak a-band power was reduced, in the participants with ASD. Induced a-band power of components that were in or near the cingulate gyrus was increased in the participants with ASD, and the components that were in or near the parietal cortex did not differ between the two groups.
CONCLUSIONS:
Atypical processing is evident in individuals with ASD during perception of simple visual stimuli. The implications of these data for existing theories of atypical perception in ASD are discussed.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Milne, E.
Secondary author(s):
Scope, A., Pascalis, O., Buckley, D., Makeig, S.
Document type:
Article
Number of reproductions:
1
Reference:
Milne, E., Scope, A., Pascalis, O., Buckley, D., & Makeig, S. (2009). Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism. Biological Psychiatry, 65(1), 22-30. https://doi.org/10.1016/j.biopsych.2008.07.017
2-year Impact Factor: 8.926|2009
Times cited: 104|2024-02-05
Indexed document: Yes
Quartile: Q1
Keywords: Alpha power / Autism / Cingulate gyrus / Gamma power / Perception / Spatial frequency / Visual cortex

Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism

Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism

DocumentReproducibility of a rapid visual brain mapping protocol2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-016
Location: Arquivo PCA - Pasta 24/2004
Title:
016 - Perceptual memory in the human visual system
Duration: 2006-02 - 2010-04
Researcher(s):
Patrícia Margarida Piedade Figueiredo, Mafalda Cavalheiro Gomes Moreira Mendes, Maria Fátima Loureiro da Silva, João Abel Loureiro Marques Xavier, Carlos Gomes
Institution(s): Instituto Biofísico para a Investigação em Luz e Imagem (IBILI), Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Abstracts and posters
Informed consent forms
Review of the final report
Language: eng
Author:
Figueiredo, P.
Secondary author(s):
Mendes, M., Silva, M. F., Xavier, J., Gomes, C.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Cognitive processes / Memory / Learning / Perception / Biopsychological problems / Diseases/Injuries / Epilepsy

Reference code: PT/FB/BL-2004-016.05
Location: Arquivo PCA - Pasta 24/2004
Title:
Reproducibility of a rapid visual brain mapping protocol
Publication year: 2009
Accessibility:
Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Cruz, P.
Secondary author(s):
Teixeira, J., Figueiredo, P.
Document type:
Abstract
Number of reproductions:
1
Reference:
Cruz, P., Teixeira, J., & Figueiredo, P. (2009). Reproducibility of a rapid visual brain mapping protocol. NeuroImage, 47(Suppl. 1), S63. https://doi.org/10.1016/S1053-8119(09)70315-5
Indexed document: Yes
Keywords: Brain mapping / Visual cortex

Reproducibility of a rapid visual brain mapping protocol

Reproducibility of a rapid visual brain mapping protocol

DocumentModeling the top-down influences on the lateral interactions in the visual cortex2008

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-080
Location: Arquivo PCA - Pasta 19/2006
Title:
080 - Understanding the role of dendrites in cortical information processing
Duration: 2007-02 - 2010-02
Researcher(s):
Drazen Domijan, Mladenka Tkalcic, Mia Setic, Ana Prorokvic, Pavle Valerjev
Institution(s): Dep. of Psychology, Faculty of Arts and Sciences, University of Rijeka, Rijeka (Croatia)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
4 Book chapters
5 Articles
3 Conference papers
Language: eng
Author:
Domijan, D.
Secondary author(s):
Tkalcic, M., Šetic, M., Prorokvic, A., Valerjev, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes / Attention / Memory / Perception / Body structure and function / Vision

Reference code: PT/FB/BL-2006-080.05
Location: Arquivo PCA - Pasta 19/2006
Title:
Modeling the top-down influences on the lateral interactions in the visual cortex
Publication year: 2008
URL:
http://www.sciencedirect.com/science/article/pii/S0006899308013164
Abstract/Results: ABSTRACT:
Attention modulates the amount of excitatory and inhibitory lateral interactions in the visual cortex. A recurrent neural network is proposed to account for modulatory influence of top-down signals. In the model, two types of inhibitions are distinguished: dendritic and lateral inhibitions. Dendritic inhibition regulates the amount of impact that surrounding cells may exert on a target cell via the dendrites of excitatory neurons and the dendrites of subpopulation of inhibitory neurons mediating lateral inhibition. Attention increases the amount of dendritic inhibition and prevents contextual interactions, while it has no effect on the target cell when there is no surround input. Computer simulations showed that the proposed model is able to exhibit properties of attentional gating. In the condition of focused attention, neural activity in the presence of surrounding stimuli is restored to the level as when the target stimulus is presented alone. Moreover, the model is able to show contrast gain and response gain on the contrast sensitivity function depending on the strength of the dendritic inhibition.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Šetic, M.
Secondary author(s):
Domijan, D.
Document type:
Article
Number of reproductions:
1
Reference:
Šetic, M., & Domijan, D. (2008). Modeling the top-down influences on the lateral interactions in the visual cortex. Brain Research, 1225, 86-101. https://doi.org/10.1016/j.brainres.2008.05.076
2-year Impact Factor: 2.494|2008
Times cited: 3|2024-02-05
Indexed document: Yes
Quartile: Q3
Keywords: Attention / Contrast / Contour integration / Visual cortex / Dendritic inhibition

Modeling the top-down influences on the lateral interactions in the visual cortex

Modeling the top-down influences on the lateral interactions in the visual cortex

DocumentA neural model for attentional modulation of lateral interactions in the visual cortex2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-080
Location: Arquivo PCA - Pasta 19/2006
Title:
080 - Understanding the role of dendrites in cortical information processing
Duration: 2007-02 - 2010-02
Researcher(s):
Drazen Domijan, Mladenka Tkalcic, Mia Setic, Ana Prorokvic, Pavle Valerjev
Institution(s): Dep. of Psychology, Faculty of Arts and Sciences, University of Rijeka, Rijeka (Croatia)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
4 Book chapters
5 Articles
3 Conference papers
Language: eng
Author:
Domijan, D.
Secondary author(s):
Tkalcic, M., Šetic, M., Prorokvic, A., Valerjev, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Cognitive processes / Attention / Memory / Perception / Body structure and function / Vision

Reference code: PT/FB/BL-2006-080.09
Location: Arquivo PCA - Pasta 19/2006
Title:
A neural model for attentional modulation of lateral interactions in the visual cortex
Publication year: 2007
URL:
http://link.springer.com/chapter/10.1007%2F978-3-540-75555-5_5
Abstract/Results: ABSTRACT:
Neurophysiological investigations showed that attention influences neural responses in the visual cortex by modulating the amount of contextual interactions between cells. Attention acts as a gate that protects cells from lateral excitatory and inhibitory influences. A recurrent neural network based on dendritic inhibition is proposed to account for these findings. In the model, two types of inhibition are distinguished: dendritic and lateral inhibition. Dendritic inhibition regulates the amount of impact that surrounding cells may exert on a target cell via dendrites of excitatory neurons and dendrites of subpopulation of inhibitory neurons mediating lateral inhibition. Attention increases the amount of dendritic inhibition and prevents contextual interactions, while it has no effect on the target cell when there is no contextual input. Computer simulations showed that the proposed model reproduces the results of several studies about interaction between attention and horizontal connections in the visual cortex.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Šetic, M.
Secondary author(s):
Domijan, D.
Document type:
Conference paper
Number of reproductions:
1
Reference:
Šetic, M., & Domijan, D. (2007). A neural model for attentional modulation of lateral interactions in the visual cortex. In F. Mele, G. Ramella, S. Santillo, & F. Ventriglia (Eds.), Advances in brain, vision, and artificial intelligence, (pp. 42-51). Berlin, Germany: Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-75555-5_5
Times cited: 3|2024-02-05
Indexed document: Yes
Keywords: Attention / Contrast / Contour integration / Visual Cortex / Dendritic inhibition

A neural model for attentional modulation of lateral interactions in visual cortex

A neural model for attentional modulation of lateral interactions in visual cortex

DocumentMagnetic stimulation of visual cortex impairs perceptual learning2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-122
Location: BF-GMS
Title:
122 - Internal and External World in Parietal Cortex
Duration: 2015-02 - 2016-09
Researcher(s):
Paolo Capotosto
Institution(s): Department of Neuroscience, Imaging and Clinical Science, University "G. D'Annunzio", Chieti (Italy)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
2 Articles
Language: eng
Author:
Capotosto, P.
Number of reproductions:
1
Keywords:
Parietal cortex / Dorsal Attention Network / Default-Mode Network / EEG rhythms / Psychophysiology

Reference code: PT/FB/BL-2014-122.03
Location: BF-GMS
Title:
Magnetic stimulation of visual cortex impairs perceptual learning
Publication year: 2016
URL:
http://www.sciencedirect.com/science/article/pii/S1053811916304566
Abstract/Results: ABSTRACT:
The ability to learn and process visual stimuli more efficiently is important for survival. Previous neuroimaging studies have shown that perceptual learning on a shape identification task differently modulates activity in both frontal-parietal cortical regions and visual cortex (Sigman et al., 2005;Lewis et al., 2009). Specifically, fronto-parietal regions (i.e. intra parietal sulcus, pIPS) became less activated for trained as compared to untrained stimuli, while visual regions (i.e. V2d/V3 and LO) exhibited higher activation for familiar shape. Here, after the intensive training, we employed transcranial magnetic stimulation over both visual occipital and parietal regions, previously shown to be modulated, to investigate their causal role in learning the shape identification task. We report that interference with V2d/V3 and LO increased reaction times to learned stimuli as compared to pIPS and Sham control condition. Moreover, the impairment observed after stimulation over the two visual regions was positive correlated. These results strongly support the causal role of the visual network in the control of the perceptual learning.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Baldassare, L.
Secondary author(s):
Capotosto, P., Committeri, G., Corbetta, M.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Baldassarre, A., Capotosto, P., Committeri, G., & Corbetta, M. (2016). Magnetic stimulation of visual cortex impairs perceptual learning. Neuroimage, 143, 250-255. https://doi.org/10.1016/j.neuroimage.2016.08.063
2-year Impact Factor: 5.835|2016
Times cited: 14|2024-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Perceptual learning / Transcranial magnetic stimulation (TMS) / Visual cortex

DocumentVolitional modulation of primary visual cortex activity requires the basal ganglia2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-413
Location: BF-GMS
Title:
413 - The role of dopamine in behavioral exploration and action selection
Duration: 2015-03 - 2018-06
Researcher(s):
Aaron Christopher Koralek
Institution(s): Champalimaud Neuroscience Programme, Lisboa (Portugal)
Contents: Contents:
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Koralek, A. C.
Number of reproductions:
1
Keywords:
Dopamine / Action selection / Basal ganglia / In vivo imaging / Psychophysiology

Reference code: PT/FB/BL-2014-413.02
Location: BF-GMS
Title:
Volitional modulation of primary visual cortex activity requires the basal ganglia
Publication year: 2018
URL:
https://www.sciencedirect.com/science/article/pii/S089662731830076X#ack0010
Abstract/Results: ABSTRACT:
Animals acquire behaviors through instrumental conditioning. Brain-machine interfaces have used instrumental conditioning to reinforce patterns of neural activity directly, especially in frontal and motor cortices, which are a rich source of signals for voluntary action. However, evidence suggests that activity in primary sensory cortices may also reflect internally driven processes, instead of purely encoding antecedent stimuli. Here, we show that rats and mice can learn to produce arbitrary patterns of neural activity in their primary visual cortex to control an auditory cursor and obtain reward. Furthermore, learning was prevented when neurons in the dorsomedial striatum (DMS), which receives input from visual cortex, were optogenetically inhibited, but not during inhibition of nearby neurons in the dorsolateral striatum. After learning, DMS inhibition did not affect production of the rewarded patterns. These data demonstrate that cortico-basal ganglia circuits play a general role in learning to produce cortical activity that leads to desirable outcomes.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Neely, R.
Secondary author(s):
Koralek, A., Athalye, V. R., Costa, R. M., Carmena, J. M.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Neely, R., Koralek, A., Athalye, V. R., Costa, R. M., & Carmena, J. M. (2018). Volitional modulation of primary visual cortex activity requires the basal ganglia. Neuron, 97(6),1356–1368.e4. https://doi.org/10.1016/j.neuron.2018.01.051
2-year Impact Factor: 14.403|2018
Times cited: 25|2024-02-09
Indexed document: Yes
Quartile: Q1
Keywords: Brain-machine interface / Visual cortex / Striatum / Learning / Optogenetics / Instrumental conditioning

DocumentAge-related changes in cortical connectivity influence the neuromodulatory effects of transcranial electrical stimulation2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-277
Location: BF-GMS
Title:
277 - Cortical excitability and connectivity in the lifespan: a neurophysiological study
Duration: 2015-09 - 2019-06
Researcher(s):
Anna Fertonani, Cornelia Pirulli
Institution(s): IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Fertonani, A.
Secondary author(s):
Pirulli, C., Bollini, A.
Number of reproductions:
1
Keywords:
Aging / Neuroplasticity / Brain stimulation techniques / TMS-EEG / Psychophysiology

Reference code: PT/FB/BL-2014-277.03
Location: BF-GMS
Title:
Age-related changes in cortical connectivity influence the neuromodulatory effects of transcranial electrical stimulation
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0197458019302118
Abstract/Results: ABSTRACT:
Transcranial electrical stimulation (tES) is a potentially viable tool for boosting cognitive performance in aging. However, most knowledge on tES effects is based on studies involving young adults. Here, we applied tES (transcranial random noise stimulation [tRNS] as an effective stimulation and anodal transcranial direct current stimulation [atDCS] as a “control” stimulation) to the visual cortex during visual perceptual learning (VPL) in healthy young and older individuals. Moreover, we measured transcranial magnetic stimulation–evoked potentials to investigate the neurophysiological underpinnings of tES effects. We found that only the tRNS in the young, but not in the older, subjects modulated VPL, by decreasing performance. Transcranial magnetic stimulation–evoked potentials revealed age-related changes in connectivity, that is, a stronger activation of the prefrontal cortex after visual cortex stimulation, and a stronger modulation of the prefrontal cortex after VPL in the older subjects. These results may indicate that task performance in older adults relies on the recruitment of a wider network and a crucial contribution of the anterior portion of the brain, which may dramatically influence tES effects in aging.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Fertonani, A.
Secondary author(s):
Pirulli, C., Bollini, A., Miniussi, C., Bortoletto, M.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Fertonani, A., Pirulli, C., Bollini, A., Miniussi, C., & Bortoletto, M. (2019). Age-related changes in cortical connectivity influence the neuromodulatory effects of transcranial electrical stimulation. Neurobiology of Aging, 82, 77-87. https://doi.org/10.1016/j.neurobiolaging.2019.07.009
2-year Impact Factor: 4.347|2019
Impact factor notes: Impact factor not available yet for 2019
Times cited: 9|2024-02-12
Indexed document: Yes
Quartile: Q1
Keywords: Learning / TMS-EEG / Visual cortex / Connectivity / Plasticity / Noninvasive brain stimulation