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BIAL Foundation
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TI:"Age-related differences and sexual dimorphism in canine sleep spindles"
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DocumentAge-related differences and sexual dimorphism in canine sleep spindles2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-169
Location: BF-GMS
Title:
169 - The potential effect of behavioral stimulation on social competence in dogs (via endogenous oxytocin release)
Duration: 2017-01 - 2021-11
Researcher(s):
Anna Kis, József Topál, Alin Ciobica, Radu Lefter, Katinka Tóth
Institution(s): Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest (Hungary); Department of Animal Physiology and Behaviour "Alexandru Ioan Cuza" University, Iasi (Romania)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress Report
Final Report
Articles
Author: Kis, A.
Secondary author(s):
Topál, J., Ciobica, A., Lefter, R., Tóth, K.
Number of reproductions:
1
Keywords:
Dog (Canis familiaris) / Social stimutation / Oxytocin / Social cognition / Psychophysiology

Reference code: PT/FB/BL-2016-169.14
Location: BF-GMS
Title:
Age-related differences and sexual dimorphism in canine sleep spindles
Publication year: 2019
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626048/
Abstract/Results: ABSTRACT:
Non-REM bursts of activity in the sigma range (9–16?Hz) typical of sleep spindles predict learning in dogs, similar to humans and rats. Little is known, however, about the age-related changes in amplitude, density (spindles/minute) and frequency (waves/second) of canine spindles. We investigated a large sample (N?=?155) of intact and neutered pet dogs of both sexes, varying in breed and age, searching for spindles in segments of non-REM sleep. We recorded EEG from both a frontal midline electrode (Fz) and a central midline electrode (Cz) in 55.5% of the dogs, in the remaining animals only the Fz electrode was active (bipolar derivation). A similar topography was observed for fast (=13?Hz) spindle occurrence as in humans (fast spindle number, density on Cz?>?Fz). For fast spindles, density was higher in females, and increased with age. These effects were more pronounced among intact animals and on Fz. Slow spindle density declined and fast spindle frequency increased with age on Cz, while on Fz age-related amplitude decline was observed. The frequency of fast spindles on Fz and slow spindles on Cz was linked to both sex and neutering, suggesting modulation by sexual hormones. Intact females displayed higher frequencies than males and neutered females. Our findings support the argument that sigma bursts in the canine non-REM sleep are analogous to human sleep spindles, and suggest that slow and fast spindles display different trajectories related to age, of which an increase in frontal fast spindles is unique to dogs.
Accessibility: Document exists in file
Language:
eng
Author:
Iotchev, I. B.
Secondary author(s):
Kis, A., Turcsán, B., Tejeda Fernández de Lara, D. R., Reicher, V., Kubinyi, E.
Document type:
Article
Number of reproductions:
1
Percentiles:
76.49|1.22
Reference:
Iotchev, I. B., Kis, A., Turcsán, B., Tejeda Fernández de Lara, D. R., Reicher, V., & Kubinyi, E. (2019). Age-related differences and sexual dimorphism in canine sleep spindles. Scientific reports, 9(1), 10092. https://doi.org/10.1038/s41598-019-46434-y
2-year Impact Factor: 3.998|2019
Times cited: 31|2026-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Sleep spindles / non-REM sleep / Sexual hormones

Age-related diferences and sexual dimorphism in canine sleep spindles

Age-related diferences and sexual dimorphism in canine sleep spindles