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BIAL Foundation
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TI:"EEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation"
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DocumentEEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation2025

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-272
Location: BF-GMS
Title:
272 - Advancements on the aware mind-brain: New insights about the neural correlates of meditation states and traits
Duration: 2021-03 - 2024-09
Researcher(s):
Antonino Raffone, Vasil Kolev, Peter Malinowski, Juliana Yordanova, Roumen Kirov
Institution(s): Department of Psychology, “Sapienza” University of Rome (Italy); Bulgarian Academy of Sciences, Sofia (Bulgaria); Liverpool John Moores University (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Final Report
Articles
Language: eng
Author:
Raffone, A.
Secondary author(s):
Kolev, V., Malinowski, P., Yordanova, J., Kirov, R.
Number of reproductions:
3
Keywords:
Meditation / Awareness / Electroencephalography / Neuroplasticity / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2020-272.06
Location: BF-GMS
Title:
EEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation
Publication year: 2025
URL:
https://doi.org/10.1038/s41598-025-94223-7
Abstract/Results: ABSTRACT:
The experience of pain is a combined product of bottom-up and top-down influences mediated by attentional and emotional factors. Meditation states and traits are characterized by enhanced attention/emotion regulation and expanded self-awareness that can be expected to modify pain processing. The main objective of the present study was to explore the effects of long-term meditation on neural mechanisms of pain processing. EEG pain-related oscillations (PROs) were analysed in highly experienced practitioners and novices during a non-meditative resting state with respect to (a) local frequency-specific and temporal synchronizing characteristics to reflect mainly bottom-up mechanisms, (b) spatial synchronizing patterns to reflect the neural communication of noxious information, (c) pre-stimulus oscillations to reflect top-down mechanisms during pain expectancy, and (d) the P3b component of the pain-related potential to compare the emotional/cognitive reappraisal of pain events by expert and novice meditators. Main results demonstrated that in experienced (long-term) meditators as compared to non-experienced (short-term) meditators (1) the temporal and spatial synchronizations of multispectral (from theta-alpha to gamma) PROs were substantially suppressed at primary and secondary somatosensory regions contra-lateral to pain stimulation within 200 ms after noxious stimulus; (2) pre-stimulus alpha activity was significantly increased at the same regions, which predicted the suppressed synchronization of PROs in long-term meditators; (3) the decrease of the P3b component was non-significant. These novel observations provide evidence that even when subjected to pain outside of meditation, experienced meditators exhibit a pro-active top-down inhibition of somatosensory areas resulting in suppressed processing and communication of sensory information at early stages of painful input. The emotional/cognitive appraisal of pain is reduced but remains preserved revealing a capacity of experienced meditators to dissociate pro-active and reactive top-down processes during pain control.
Accessibility: Document exists in file
Language:
eng
Author:
Yordanova, J.
Secondary author(s):
Nicolardi, V., Malinowski, P., Simione, L., Aglioti, S. M., Raffone, A., Kolev, V.
Document type:
Article
Number of reproductions:
3
Percentiles:
0.00|0.00
Reference:
Yordanova, J., Nicolardi, V., Malinowski, P., Simione, L., Aglioti, S. M., Raffone, A., & Kolev, V. (2025). EEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation. Scientific Reports, 15(1), 10604. https://doi.org/10.1038/s41598-025-94223-7
2-year Impact Factor: 3.9|2024
Impact factor notes: Impact factor not available yet for 2025
Times cited: 0|2026-02-17
Indexed document: Yes
Quartile: Q1
Keywords: Pain / Meditation / EEG / Pain-related oscillations

EEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation

EEG oscillations reveal neuroplastic changes in pain processing associated with long-term meditation