| Reference code: | PT/FB/BL-2000-054.10 |
| Location: | Arquivo PCA - Pasta 3/2000
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Title:
| Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
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| Publication year: | 2004
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URL:
| http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/5%C2%BA_simposio.a111.html
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| Abstract/Results: | ABSTRACT:
Behavioural interventions including biofeedback represent an alternative or adjunctive therapeutic axis in the management of drug refractory epilepsy. Our previous study suggested that the modulation of the peripheral state of arousal as indexed by the Galvanic Skin Response (GSR) had considerable influence on cortical excitability, indicating the possible use of biofeedback in controlling seizure activity.
We investigated the effect of the GSR biofeedback training on seizure frequency in patients with treatment resistant epilepsy. Eighteen patients with drug refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n = 10) or to a sham control biofeedback group (n = 8). Patients received a total of 12 sessions over four weeks, representing either real GSR biofeedback training, where subjects were trained to decrease skin resistance using biofeedback, or sham training, where the feedback was unrelated to the subjects’ GSR. Biofeedback training significantly reduced patients’ seizure frequency in the active biofeedback group (p = 0.017), but not the control group (p>0.10). This was manifest as a significant between group difference in seizure reduction (p = 0.01). Our findings demonstrate that a behavioural intervention, GSR biofeedback training, may substantially reduce seizure frequency in drug refractory epilepsy, highlighting the potential therapeutic value of this method.
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| Accessibility: | Document does not exist in file
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Language:
| eng
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Author:
| Nagai, Y.
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Secondary author(s):
| Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
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Document type:
| Conference abstract
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Number of reproductions:
| 1
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Reference:
| Nagai, Y., Trimble, M. R., Fenwick, P., Goldstein, L., & Lumsden, J. (2004). Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 5th Symposium of Fundação Bial (pp. 306-307). Porto: Fundação Bial. |
| Indexed document: | No
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| Keywords: | Psychophysiology / Epilepsy / Galvanic skin response (GSR)
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