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BIAL Foundation
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TI:"Fear in action: Pavlovian threat learning shapes corticospinal excitability"
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DocumentFear in action: Pavlovian threat learning shapes corticospinal excitability2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-047
Location: BF-GMS
Title:
047 - Fear in action: How Pavlovian fear learning shapes goal-directed motor responses
Duration: 2021-03 - 2024-03
Researcher(s):
Francesca Starita, Giuseppe di Pellegrino
Institution(s): Centre for Studies and Research in Cognitive Neuroscience - CsrNC, Department of Psychology, University of Bologna (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Starita, F.
Secondary author(s):
di Pellegrino, G.
Number of reproductions:
1
Keywords:
Pavlovian learning / Goal-directed action / Motor cortex / Fear / Psychophysiology

Reference code: PT/FB/BL-2020-047.11
Location: BF-GMS
Title:
Fear in action: Pavlovian threat learning shapes corticospinal excitability
Publication year: 2022
URL:
https://www.sipf.it/resources/Documents/CONGRESSO%20NAZIONALE%202022/ABSTRACT%20CO/Betti%20Sonia.pdf
Abstract/Results: ABSTRACT:
Environmental stimuli may acquire fear-related properties through pairing with an aversive event, but the extent to which threat learning shapes the motor system response remains largely unexplored. In the present study, during Pavlovian threat learning, two different neutral stimuli (i.e., colored dots) acquired threat-related value by predicting an aversive shock to either the left (i.e., conditioned stimulus left, CS+L) or right (CS+R) arm. Another stimulus (i.e., CS-) never predicted shocks. We collected electrodermal activity to characterize changes in psychophysiological arousal between CSs. Additionally, changes in corticospinal excitability (CSE) were assessed by acquiring motor-evoked potentials (MEP) elicited by transcranial magnetic stimulation (TMS) delivered to the participant’s left primary motor cortex. We found increased skin conductance responses (SCRs) for CS+R and CS+L compared to the CS-, which did not distinguish the laterality of the upcoming shock. Conversely, a lateralized inhibitory effect emerged for corticospinal excitability. Indeed, we found a reduction in MEP amplitude for the CS+R, compared to the CS+L and the CS-. Our results show the motor system’s involvement in threat-related response learning, and highlight the existence of multiple, dissociable learning systems, namely a general non-lateralized autonomic system and a specific lateralized motor one.
Accessibility: Document exists in file
Language:
eng
Author:
Betti, S.
Secondary author(s):
Badioli, M., Garofalo, S., di Pellegrino, G., Starita, F.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Betti, S., Badioli, M., Garofalo, S., di Pellegrino, G., & Starita, F. (2022, 15-17 September). Fear in action: Pavlovian threat learning shapes corticospinal excitability [Conference presentation abstract]. Società Italiana di Psicofisiologia e Neuroscienze Cognitive (SIPF), Udine, Italy. https://www.sipf.it/resources/Documents/CONGRESSO%20NAZIONALE%202022/ABSTRACT%20CO/Betti%20Sonia.pdf
Indexed document: No
Keywords: Pavlovian threat learning / Corticospinal excitability / Motor system

Fear in action: Pavlovian threat learning shapes corticospinal excitability

Fear in action: Pavlovian threat learning shapes corticospinal excitability