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BIAL Foundation
TI:"Final report - A neuropsychological examination of orbitofrontal cortex function in eating disorders "
Selection Description
Type Title Begin End
DocumentFinal report - A neuropsychological examination of orbitofrontal cortex function in eating disorders 2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
BIAL Foundation Archive
Start date: 1994
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
2002 Grants
Start date: 2003-01 - 2009-11
21 caixas de arquivo

Reference code: PT/FB/BL-2002-088
Location: Arquivo PCA - Pasta 6/2002
088 - A neuropsychological examination of orbitofrontal cortex function in eating disorders
Duration: 2003-03 - 2004-09
Janet Treasure, Kate Tchanturia
Institution(s): Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Financial report and expenditure documents
Progress reports
Final report
Brochures (newsletters)
Language: eng
Related objects:
Author: Treasure, J.
Secondary author(s):
Tchanturia, K.
Number of reproductions:
Psychophysiology / Biopsychological problems / Mental health / Eating disorders / Cognitive processes / Decision-making

Reference code: PT/FB/BL-2002-088.01
Location: Arquivo PCA - Pasta 6/2002
Final report - A neuropsychological examination of orbitofrontal cortex function in eating disorders
Publication year: 2004
Abstract/Results: RESULTS:
Previous neuroimaging findings implicate an orbitofrontal cortical dysfunction in the pathogenesis of anorexia nervosa (Uher 2003). The orbitofrontal cortex is necessary for practical decision-making in humans and the Iowa Gambling task (IGT) became established as an instrument for investigation of decision making and orbitofrontal function (Bechara 2002).
Using the computerised IGT, we investigated the profile of decision making performance in anorexia nervosa female patients (n=29), male patients with anorexia (n=11) long term recovered participants (n=27), healthy control females (29), healthy males (N=25). Skin conductance response during the task was measured using the PSYLAB equipment.
As expected, the healthy control women made progressively more advantageous choices during the task. Patients with AN failed to show this learning effect and continued making disadvantageous choices throughout the task. Those recovered form AN, showed a normal learning curve and their performance was no worse than that of healthy controls in the IGT.
The impairment of decision-making in AN is replication of previous findings (Cavedini 2004). However, decision-making in women recovered form AN was not previously reported and may elucidate the role of this cognitive function in the pathogenesis and course of the illness. This pattern of results may suggest that impaired decision-making is either a state marker of AN and improvement in decision-making is part of the process of recovery or it may be that decision-making capacity is a positive prognostic factor which makes it possible to attain full recovery. To distinguish between these two distinct possibilities, longitudinal investigation is warranted.
Accessibility: Document exists in file
By permission
Treasure, J.
Secondary author(s):
Tchanturia, K.
Document type:
Final report
Number of reproductions:
Indexed document:
Keywords: Psychophysiology / Psychopathology / Eating disorders / Anorexia nervosa / Decision-making

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