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BIAL Foundation
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TI:"Final report - High-frequency oscillations and rhythmic slow activity during virtual navigation, REM sleep and wake-sleep transitions: Studies on intracranial recordings in humans"
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DocumentFinal report - High-frequency oscillations and rhythmic slow activity during virtual navigation, REM sleep and wake-sleep transitions: Studies on intracranial recordings in humans2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

Reference code: PT/FB/BL-2006-154
Location: Arquivo PCA - Pasta 5/2006
Title:
154 - High-frequency oscillations and rhythmic slow activity during virtual navigation, REM sleep and wake-sleep transitions: Studies on intracranial recordings in humans
Duration: 2008-01 - 2009-10
Researcher(s):
Péter Halász, Zsófia Clemens, Csaba Borbély, Daniel Fabó
Institution(s): Budapest-Bethel Epilepsy Center Foundation (BBEC), Budapest (Hungary)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Language: eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Sleep and dreams / Biopsychological problems / Diseases/Injuries / Epilepsy

Reference code: PT/FB/BL-2006-154.01
Location: Arquivo PCA - Pasta 5/2006
Title:
Final report - High-frequency oscillations and rhythmic slow activity during virtual navigation, REM sleep and wake-sleep transitions: Studies on intracranial recordings in humans
Publication year: 2009
URL:
http://www.bial.com/imagem/Bolsa15406_21022014.pdf
Abstract/Results: RESULTS:
This study relied on nine epilepsy surgery candidates implanted with foramen ovale electrodes. 1.5-3Hz rhythmic slow activity (RSA) was a predominant activity pattern during REM sleep in most patients. This activity was also found to be highly synchronous both intra- and interhemispherically. Positive half-waves of the 1.5–3Hz RSA were identified by a semi-automatic algorithm during REM sleep. High-frequency activity was assessed as root mean square (RMS) for 11 consecutive 20 Hz–wide frequency bands between 20 and 240Hz. Calculating individual spectra revealed a broad but definite peak in the high-frequency band in seven cases (hemispheres). Statistical analysis revealed a clear phase-coupling of high-frequency activity in all patients and for most of the high-frequency bands studied. This phase relation was similar across the high frequency bands within the same patient and hemisphere. This allowed us to use individually defined fixed intervals of 0.1 s to statistically compare RMS values corresponding to the peak and the trough of the triggered RMS curve. Typically the preferred phase occurred before the RSA peak used as trigger. In most cases modulation statistics exhibited a U-shaped curve with highest significance levels in the middle frequency bands (60–80Hz and 80–100Hz). Compared to these bands modulation generally weakened across both decreasing and increasing frequency ranges. Such a phase-coupling between delta and gamma activity is similar to that seen between theta and gamma in rodents. We consider this commonality to be an additional reason for regarding delta rather than theta as the human analogue of RSA in animals.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Halász, P.
Secondary author(s):
Clemens, Z., Borbély, C., Fabó, D.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Sleep / Epilepsy / Rhythmic slow activity

Final report - High-frequency oscillations and rhythmic slow activity during virtual navigation, REM sleep and wake-sleep transitions: Studies on intracranial recordings in humans

Final report - High-frequency oscillations and rhythmic slow activity during virtual navigation, REM sleep and wake-sleep transitions: Studies on intracranial recordings in humans